data_AF-O43570-F1
#
_entry.id AF-O43570-F1
#
loop_
_atom_type.symbol
C 
N 
O 
S 
#
loop_
_audit_author.name
_audit_author.pdbx_ordinal
"Jumper, John"               1  
"Evans, Richard"             2  
"Pritzel, Alexander"         3  
"Green, Tim"                 4  
"Figurnov, Michael"          5  
"Ronneberger, Olaf"          6  
"Tunyasuvunakool, Kathryn"   7  
"Bates, Russ"                8  
"Zidek, Augustin"            9  
"Potapenko, Anna"            10 
"Bridgland, Alex"            11 
"Meyer, Clemens"             12 
"Kohl, Simon A. A."          13 
"Ballard, Andrew J."         14 
"Cowie, Andrew"              15 
"Romera-Paredes, Bernardino" 16 
"Nikolov, Stanislav"         17 
"Jain, Rishub"               18 
"Adler, Jonas"               19 
"Back, Trevor"               20 
"Petersen, Stig"             21 
"Reiman, David"              22 
"Clancy, Ellen"              23 
"Zielinski, Michal"          24 
"Steinegger, Martin"         25 
"Pacholska, Michalina"       26 
"Berghammer, Tamas"          27 
"Silver, David"              28 
"Vinyals, Oriol"             29 
"Senior, Andrew W."          30 
"Kavukcuoglu, Koray"         31 
"Kohli, Pushmeet"            32 
"Hassabis, Demis"            33 
#
_audit_conform.dict_location https://raw.githubusercontent.com/ihmwg/ModelCIF/master/dist/mmcif_ma.dic
_audit_conform.dict_name     mmcif_ma.dic
_audit_conform.dict_version  1.3.9
#
loop_
_chem_comp.formula
_chem_comp.formula_weight
_chem_comp.id
_chem_comp.mon_nstd_flag
_chem_comp.name
_chem_comp.pdbx_synonyms
_chem_comp.type
"C3 H7 N O2"    89.093  ALA y ALANINE         ? "L-PEPTIDE LINKING" 
"C6 H15 N4 O2"  175.209 ARG y ARGININE        ? "L-PEPTIDE LINKING" 
"C4 H8 N2 O3"   132.118 ASN y ASPARAGINE      ? "L-PEPTIDE LINKING" 
"C4 H7 N O4"    133.103 ASP y "ASPARTIC ACID" ? "L-PEPTIDE LINKING" 
"C3 H7 N O2 S"  121.158 CYS y CYSTEINE        ? "L-PEPTIDE LINKING" 
"C5 H10 N2 O3"  146.144 GLN y GLUTAMINE       ? "L-PEPTIDE LINKING" 
"C5 H9 N O4"    147.129 GLU y "GLUTAMIC ACID" ? "L-PEPTIDE LINKING" 
"C2 H5 N O2"    75.067  GLY y GLYCINE         ? "PEPTIDE LINKING"   
"C6 H10 N3 O2"  156.162 HIS y HISTIDINE       ? "L-PEPTIDE LINKING" 
"C6 H13 N O2"   131.173 ILE y ISOLEUCINE      ? "L-PEPTIDE LINKING" 
"C6 H13 N O2"   131.173 LEU y LEUCINE         ? "L-PEPTIDE LINKING" 
"C6 H15 N2 O2"  147.195 LYS y LYSINE          ? "L-PEPTIDE LINKING" 
"C5 H11 N O2 S" 149.211 MET y METHIONINE      ? "L-PEPTIDE LINKING" 
"C9 H11 N O2"   165.189 PHE y PHENYLALANINE   ? "L-PEPTIDE LINKING" 
"C5 H9 N O2"    115.130 PRO y PROLINE         ? "L-PEPTIDE LINKING" 
"C3 H7 N O3"    105.093 SER y SERINE          ? "L-PEPTIDE LINKING" 
"C4 H9 N O3"    119.119 THR y THREONINE       ? "L-PEPTIDE LINKING" 
"C11 H12 N2 O2" 204.225 TRP y TRYPTOPHAN      ? "L-PEPTIDE LINKING" 
"C9 H11 N O3"   181.189 TYR y TYROSINE        ? "L-PEPTIDE LINKING" 
"C5 H11 N O2"   117.146 VAL y VALINE          ? "L-PEPTIDE LINKING" 
#
_citation.book_publisher          ?
_citation.country                 UK
_citation.id                      1
_citation.journal_full            Nature
_citation.journal_id_ASTM         NATUAS
_citation.journal_id_CSD          0006
_citation.journal_id_ISSN         0028-0836
_citation.journal_volume          596
_citation.page_first              583
_citation.page_last               589
_citation.pdbx_database_id_DOI    10.1038/s41586-021-03819-2
_citation.pdbx_database_id_PubMed 34265844
_citation.title                   "Highly accurate protein structure prediction with AlphaFold"
_citation.year                    2021
#
loop_
_citation_author.citation_id
_citation_author.name
_citation_author.ordinal
1 "Jumper, John"               1  
1 "Evans, Richard"             2  
1 "Pritzel, Alexander"         3  
1 "Green, Tim"                 4  
1 "Figurnov, Michael"          5  
1 "Ronneberger, Olaf"          6  
1 "Tunyasuvunakool, Kathryn"   7  
1 "Bates, Russ"                8  
1 "Zidek, Augustin"            9  
1 "Potapenko, Anna"            10 
1 "Bridgland, Alex"            11 
1 "Meyer, Clemens"             12 
1 "Kohl, Simon A. A."          13 
1 "Ballard, Andrew J."         14 
1 "Cowie, Andrew"              15 
1 "Romera-Paredes, Bernardino" 16 
1 "Nikolov, Stanislav"         17 
1 "Jain, Rishub"               18 
1 "Adler, Jonas"               19 
1 "Back, Trevor"               20 
1 "Petersen, Stig"             21 
1 "Reiman, David"              22 
1 "Clancy, Ellen"              23 
1 "Zielinski, Michal"          24 
1 "Steinegger, Martin"         25 
1 "Pacholska, Michalina"       26 
1 "Berghammer, Tamas"          27 
1 "Silver, David"              28 
1 "Vinyals, Oriol"             29 
1 "Senior, Andrew W."          30 
1 "Kavukcuoglu, Koray"         31 
1 "Kohli, Pushmeet"            32 
1 "Hassabis, Demis"            33 
#
_database_2.database_code AF-O43570-F1
_database_2.database_id   AlphaFoldDB
#
_entity.details                  ?
_entity.formula_weight           ?
_entity.id                       1
_entity.pdbx_description         "Carbonic anhydrase 12"
_entity.pdbx_ec                  ?
_entity.pdbx_fragment            ?
_entity.pdbx_mutation            ?
_entity.pdbx_number_of_molecules 1
_entity.src_method               man
_entity.type                     polymer
#
_entity_poly.entity_id                    1
_entity_poly.nstd_linkage                 no
_entity_poly.nstd_monomer                 no
_entity_poly.pdbx_seq_one_letter_code     
;MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYN
LSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTA
SNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFR
NPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQVQVCTAAGLSLGIILSLALAGILGICIVV
VVSIWLFRRKSIKKGDNKGVIYKPATKMETEAHA
;
_entity_poly.pdbx_seq_one_letter_code_can 
;MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYN
LSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTA
SNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFR
NPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQVQVCTAAGLSLGIILSLALAGILGICIVV
VVSIWLFRRKSIKKGDNKGVIYKPATKMETEAHA
;
_entity_poly.pdbx_strand_id               A
_entity_poly.type                         polypeptide(L)
#
loop_
_entity_poly_seq.entity_id
_entity_poly_seq.hetero
_entity_poly_seq.mon_id
_entity_poly_seq.num
1 n MET 1   
1 n PRO 2   
1 n ARG 3   
1 n ARG 4   
1 n SER 5   
1 n LEU 6   
1 n HIS 7   
1 n ALA 8   
1 n ALA 9   
1 n ALA 10  
1 n VAL 11  
1 n LEU 12  
1 n LEU 13  
1 n LEU 14  
1 n VAL 15  
1 n ILE 16  
1 n LEU 17  
1 n LYS 18  
1 n GLU 19  
1 n GLN 20  
1 n PRO 21  
1 n SER 22  
1 n SER 23  
1 n PRO 24  
1 n ALA 25  
1 n PRO 26  
1 n VAL 27  
1 n ASN 28  
1 n GLY 29  
1 n SER 30  
1 n LYS 31  
1 n TRP 32  
1 n THR 33  
1 n TYR 34  
1 n PHE 35  
1 n GLY 36  
1 n PRO 37  
1 n ASP 38  
1 n GLY 39  
1 n GLU 40  
1 n ASN 41  
1 n SER 42  
1 n TRP 43  
1 n SER 44  
1 n LYS 45  
1 n LYS 46  
1 n TYR 47  
1 n PRO 48  
1 n SER 49  
1 n CYS 50  
1 n GLY 51  
1 n GLY 52  
1 n LEU 53  
1 n LEU 54  
1 n GLN 55  
1 n SER 56  
1 n PRO 57  
1 n ILE 58  
1 n ASP 59  
1 n LEU 60  
1 n HIS 61  
1 n SER 62  
1 n ASP 63  
1 n ILE 64  
1 n LEU 65  
1 n GLN 66  
1 n TYR 67  
1 n ASP 68  
1 n ALA 69  
1 n SER 70  
1 n LEU 71  
1 n THR 72  
1 n PRO 73  
1 n LEU 74  
1 n GLU 75  
1 n PHE 76  
1 n GLN 77  
1 n GLY 78  
1 n TYR 79  
1 n ASN 80  
1 n LEU 81  
1 n SER 82  
1 n ALA 83  
1 n ASN 84  
1 n LYS 85  
1 n GLN 86  
1 n PHE 87  
1 n LEU 88  
1 n LEU 89  
1 n THR 90  
1 n ASN 91  
1 n ASN 92  
1 n GLY 93  
1 n HIS 94  
1 n SER 95  
1 n VAL 96  
1 n LYS 97  
1 n LEU 98  
1 n ASN 99  
1 n LEU 100 
1 n PRO 101 
1 n SER 102 
1 n ASP 103 
1 n MET 104 
1 n HIS 105 
1 n ILE 106 
1 n GLN 107 
1 n GLY 108 
1 n LEU 109 
1 n GLN 110 
1 n SER 111 
1 n ARG 112 
1 n TYR 113 
1 n SER 114 
1 n ALA 115 
1 n THR 116 
1 n GLN 117 
1 n LEU 118 
1 n HIS 119 
1 n LEU 120 
1 n HIS 121 
1 n TRP 122 
1 n GLY 123 
1 n ASN 124 
1 n PRO 125 
1 n ASN 126 
1 n ASP 127 
1 n PRO 128 
1 n HIS 129 
1 n GLY 130 
1 n SER 131 
1 n GLU 132 
1 n HIS 133 
1 n THR 134 
1 n VAL 135 
1 n SER 136 
1 n GLY 137 
1 n GLN 138 
1 n HIS 139 
1 n PHE 140 
1 n ALA 141 
1 n ALA 142 
1 n GLU 143 
1 n LEU 144 
1 n HIS 145 
1 n ILE 146 
1 n VAL 147 
1 n HIS 148 
1 n TYR 149 
1 n ASN 150 
1 n SER 151 
1 n ASP 152 
1 n LEU 153 
1 n TYR 154 
1 n PRO 155 
1 n ASP 156 
1 n ALA 157 
1 n SER 158 
1 n THR 159 
1 n ALA 160 
1 n SER 161 
1 n ASN 162 
1 n LYS 163 
1 n SER 164 
1 n GLU 165 
1 n GLY 166 
1 n LEU 167 
1 n ALA 168 
1 n VAL 169 
1 n LEU 170 
1 n ALA 171 
1 n VAL 172 
1 n LEU 173 
1 n ILE 174 
1 n GLU 175 
1 n MET 176 
1 n GLY 177 
1 n SER 178 
1 n PHE 179 
1 n ASN 180 
1 n PRO 181 
1 n SER 182 
1 n TYR 183 
1 n ASP 184 
1 n LYS 185 
1 n ILE 186 
1 n PHE 187 
1 n SER 188 
1 n HIS 189 
1 n LEU 190 
1 n GLN 191 
1 n HIS 192 
1 n VAL 193 
1 n LYS 194 
1 n TYR 195 
1 n LYS 196 
1 n GLY 197 
1 n GLN 198 
1 n GLU 199 
1 n ALA 200 
1 n PHE 201 
1 n VAL 202 
1 n PRO 203 
1 n GLY 204 
1 n PHE 205 
1 n ASN 206 
1 n ILE 207 
1 n GLU 208 
1 n GLU 209 
1 n LEU 210 
1 n LEU 211 
1 n PRO 212 
1 n GLU 213 
1 n ARG 214 
1 n THR 215 
1 n ALA 216 
1 n GLU 217 
1 n TYR 218 
1 n TYR 219 
1 n ARG 220 
1 n TYR 221 
1 n ARG 222 
1 n GLY 223 
1 n SER 224 
1 n LEU 225 
1 n THR 226 
1 n THR 227 
1 n PRO 228 
1 n PRO 229 
1 n CYS 230 
1 n ASN 231 
1 n PRO 232 
1 n THR 233 
1 n VAL 234 
1 n LEU 235 
1 n TRP 236 
1 n THR 237 
1 n VAL 238 
1 n PHE 239 
1 n ARG 240 
1 n ASN 241 
1 n PRO 242 
1 n VAL 243 
1 n GLN 244 
1 n ILE 245 
1 n SER 246 
1 n GLN 247 
1 n GLU 248 
1 n GLN 249 
1 n LEU 250 
1 n LEU 251 
1 n ALA 252 
1 n LEU 253 
1 n GLU 254 
1 n THR 255 
1 n ALA 256 
1 n LEU 257 
1 n TYR 258 
1 n CYS 259 
1 n THR 260 
1 n HIS 261 
1 n MET 262 
1 n ASP 263 
1 n ASP 264 
1 n PRO 265 
1 n SER 266 
1 n PRO 267 
1 n ARG 268 
1 n GLU 269 
1 n MET 270 
1 n ILE 271 
1 n ASN 272 
1 n ASN 273 
1 n PHE 274 
1 n ARG 275 
1 n GLN 276 
1 n VAL 277 
1 n GLN 278 
1 n LYS 279 
1 n PHE 280 
1 n ASP 281 
1 n GLU 282 
1 n ARG 283 
1 n LEU 284 
1 n VAL 285 
1 n TYR 286 
1 n THR 287 
1 n SER 288 
1 n PHE 289 
1 n SER 290 
1 n GLN 291 
1 n VAL 292 
1 n GLN 293 
1 n VAL 294 
1 n CYS 295 
1 n THR 296 
1 n ALA 297 
1 n ALA 298 
1 n GLY 299 
1 n LEU 300 
1 n SER 301 
1 n LEU 302 
1 n GLY 303 
1 n ILE 304 
1 n ILE 305 
1 n LEU 306 
1 n SER 307 
1 n LEU 308 
1 n ALA 309 
1 n LEU 310 
1 n ALA 311 
1 n GLY 312 
1 n ILE 313 
1 n LEU 314 
1 n GLY 315 
1 n ILE 316 
1 n CYS 317 
1 n ILE 318 
1 n VAL 319 
1 n VAL 320 
1 n VAL 321 
1 n VAL 322 
1 n SER 323 
1 n ILE 324 
1 n TRP 325 
1 n LEU 326 
1 n PHE 327 
1 n ARG 328 
1 n ARG 329 
1 n LYS 330 
1 n SER 331 
1 n ILE 332 
1 n LYS 333 
1 n LYS 334 
1 n GLY 335 
1 n ASP 336 
1 n ASN 337 
1 n LYS 338 
1 n GLY 339 
1 n VAL 340 
1 n ILE 341 
1 n TYR 342 
1 n LYS 343 
1 n PRO 344 
1 n ALA 345 
1 n THR 346 
1 n LYS 347 
1 n MET 348 
1 n GLU 349 
1 n THR 350 
1 n GLU 351 
1 n ALA 352 
1 n HIS 353 
1 n ALA 354 
#
loop_
_ma_data.content_type
_ma_data.id
_ma_data.name
"model coordinates" 1 Model             
"input structure"   2 "Input structure" 
#
_ma_model_list.data_id          1
_ma_model_list.model_group_id   1
_ma_model_list.model_group_name "AlphaFold Monomer v2.0 model"
_ma_model_list.model_id         1
_ma_model_list.model_name       "Top ranked model"
_ma_model_list.model_type       "Ab initio model"
_ma_model_list.ordinal_id       1
#
loop_
_ma_protocol_step.method_type
_ma_protocol_step.ordinal_id
_ma_protocol_step.protocol_id
_ma_protocol_step.step_id
"coevolution MSA" 1 1 1 
"template search" 2 1 2 
modeling          3 1 3 
#
loop_
_ma_qa_metric.id
_ma_qa_metric.mode
_ma_qa_metric.name
_ma_qa_metric.software_group_id
_ma_qa_metric.type
1 global pLDDT 1 pLDDT 
2 local  pLDDT 1 pLDDT 
#
_ma_qa_metric_global.metric_id    1
_ma_qa_metric_global.metric_value 88.39
_ma_qa_metric_global.model_id     1
_ma_qa_metric_global.ordinal_id   1
#
loop_
_ma_qa_metric_local.label_asym_id
_ma_qa_metric_local.label_comp_id
_ma_qa_metric_local.label_seq_id
_ma_qa_metric_local.metric_id
_ma_qa_metric_local.metric_value
_ma_qa_metric_local.model_id
_ma_qa_metric_local.ordinal_id
A MET 1   2 38.46 1 1   
A PRO 2   2 50.96 1 2   
A ARG 3   2 42.22 1 3   
A ARG 4   2 47.96 1 4   
A SER 5   2 43.39 1 5   
A LEU 6   2 47.35 1 6   
A HIS 7   2 42.59 1 7   
A ALA 8   2 44.58 1 8   
A ALA 9   2 41.98 1 9   
A ALA 10  2 44.40 1 10  
A VAL 11  2 43.27 1 11  
A LEU 12  2 42.30 1 12  
A LEU 13  2 39.06 1 13  
A LEU 14  2 44.78 1 14  
A VAL 15  2 48.21 1 15  
A ILE 16  2 46.99 1 16  
A LEU 17  2 48.82 1 17  
A LYS 18  2 43.88 1 18  
A GLU 19  2 47.27 1 19  
A GLN 20  2 40.26 1 20  
A PRO 21  2 38.70 1 21  
A SER 22  2 38.49 1 22  
A SER 23  2 37.16 1 23  
A PRO 24  2 40.03 1 24  
A ALA 25  2 34.99 1 25  
A PRO 26  2 28.77 1 26  
A VAL 27  2 36.01 1 27  
A ASN 28  2 32.01 1 28  
A GLY 29  2 37.52 1 29  
A SER 30  2 57.67 1 30  
A LYS 31  2 83.36 1 31  
A TRP 32  2 96.07 1 32  
A THR 33  2 96.87 1 33  
A TYR 34  2 97.22 1 34  
A PHE 35  2 94.33 1 35  
A GLY 36  2 94.03 1 36  
A PRO 37  2 94.76 1 37  
A ASP 38  2 95.82 1 38  
A GLY 39  2 96.96 1 39  
A GLU 40  2 97.66 1 40  
A ASN 41  2 97.43 1 41  
A SER 42  2 97.29 1 42  
A TRP 43  2 97.94 1 43  
A SER 44  2 97.24 1 44  
A LYS 45  2 96.32 1 45  
A LYS 46  2 96.06 1 46  
A TYR 47  2 97.08 1 47  
A PRO 48  2 97.27 1 48  
A SER 49  2 97.41 1 49  
A CYS 50  2 97.91 1 50  
A GLY 51  2 96.86 1 51  
A GLY 52  2 95.59 1 52  
A LEU 53  2 95.71 1 53  
A LEU 54  2 97.32 1 54  
A GLN 55  2 98.53 1 55  
A SER 56  2 98.83 1 56  
A PRO 57  2 98.84 1 57  
A ILE 58  2 98.87 1 58  
A ASP 59  2 98.79 1 59  
A LEU 60  2 98.59 1 60  
A HIS 61  2 97.52 1 61  
A SER 62  2 95.25 1 62  
A ASP 63  2 95.79 1 63  
A ILE 64  2 97.25 1 64  
A LEU 65  2 98.02 1 65  
A GLN 66  2 97.97 1 66  
A TYR 67  2 98.18 1 67  
A ASP 68  2 97.99 1 68  
A ALA 69  2 97.17 1 69  
A SER 70  2 97.51 1 70  
A LEU 71  2 98.20 1 71  
A THR 72  2 97.36 1 72  
A PRO 73  2 98.26 1 73  
A LEU 74  2 98.37 1 74  
A GLU 75  2 98.40 1 75  
A PHE 76  2 98.62 1 76  
A GLN 77  2 98.59 1 77  
A GLY 78  2 98.35 1 78  
A TYR 79  2 98.55 1 79  
A ASN 80  2 98.59 1 80  
A LEU 81  2 98.38 1 81  
A SER 82  2 97.19 1 82  
A ALA 83  2 97.42 1 83  
A ASN 84  2 97.58 1 84  
A LYS 85  2 97.96 1 85  
A GLN 86  2 98.34 1 86  
A PHE 87  2 98.73 1 87  
A LEU 88  2 98.80 1 88  
A LEU 89  2 98.90 1 89  
A THR 90  2 98.79 1 90  
A ASN 91  2 98.67 1 91  
A ASN 92  2 97.89 1 92  
A GLY 93  2 97.84 1 93  
A HIS 94  2 98.09 1 94  
A SER 95  2 98.65 1 95  
A VAL 96  2 98.65 1 96  
A LYS 97  2 98.79 1 97  
A LEU 98  2 98.85 1 98  
A ASN 99  2 98.80 1 99  
A LEU 100 2 98.83 1 100 
A PRO 101 2 98.53 1 101 
A SER 102 2 98.26 1 102 
A ASP 103 2 97.82 1 103 
A MET 104 2 98.76 1 104 
A HIS 105 2 98.77 1 105 
A ILE 106 2 98.61 1 106 
A GLN 107 2 95.63 1 107 
A GLY 108 2 94.64 1 108 
A LEU 109 2 96.52 1 109 
A GLN 110 2 95.39 1 110 
A SER 111 2 97.32 1 111 
A ARG 112 2 98.11 1 112 
A TYR 113 2 98.80 1 113 
A SER 114 2 98.81 1 114 
A ALA 115 2 98.87 1 115 
A THR 116 2 98.76 1 116 
A GLN 117 2 98.79 1 117 
A LEU 118 2 98.89 1 118 
A HIS 119 2 98.91 1 119 
A LEU 120 2 98.90 1 120 
A HIS 121 2 98.92 1 121 
A TRP 122 2 98.85 1 122 
A GLY 123 2 98.53 1 123 
A ASN 124 2 98.49 1 124 
A PRO 125 2 98.26 1 125 
A ASN 126 2 97.97 1 126 
A ASP 127 2 97.37 1 127 
A PRO 128 2 97.16 1 128 
A HIS 129 2 98.45 1 129 
A GLY 130 2 98.56 1 130 
A SER 131 2 98.88 1 131 
A GLU 132 2 98.91 1 132 
A HIS 133 2 98.90 1 133 
A THR 134 2 98.88 1 134 
A VAL 135 2 98.64 1 135 
A SER 136 2 97.99 1 136 
A GLY 137 2 97.96 1 137 
A GLN 138 2 98.40 1 138 
A HIS 139 2 98.73 1 139 
A PHE 140 2 98.76 1 140 
A ALA 141 2 98.77 1 141 
A ALA 142 2 98.91 1 142 
A GLU 143 2 98.94 1 143 
A LEU 144 2 98.93 1 144 
A HIS 145 2 98.94 1 145 
A ILE 146 2 98.92 1 146 
A VAL 147 2 98.85 1 147 
A HIS 148 2 98.90 1 148 
A TYR 149 2 98.81 1 149 
A ASN 150 2 98.62 1 150 
A SER 151 2 98.36 1 151 
A ASP 152 2 98.07 1 152 
A LEU 153 2 98.09 1 153 
A TYR 154 2 98.34 1 154 
A PRO 155 2 97.68 1 155 
A ASP 156 2 98.19 1 156 
A ALA 157 2 97.88 1 157 
A SER 158 2 97.14 1 158 
A THR 159 2 97.56 1 159 
A ALA 160 2 98.05 1 160 
A SER 161 2 95.90 1 161 
A ASN 162 2 95.31 1 162 
A LYS 163 2 96.67 1 163 
A SER 164 2 94.09 1 164 
A GLU 165 2 94.54 1 165 
A GLY 166 2 97.78 1 166 
A LEU 167 2 98.75 1 167 
A ALA 168 2 98.83 1 168 
A VAL 169 2 98.87 1 169 
A LEU 170 2 98.92 1 170 
A ALA 171 2 98.94 1 171 
A VAL 172 2 98.94 1 172 
A LEU 173 2 98.92 1 173 
A ILE 174 2 98.93 1 174 
A GLU 175 2 98.71 1 175 
A MET 176 2 98.40 1 176 
A GLY 177 2 98.50 1 177 
A SER 178 2 98.27 1 178 
A PHE 179 2 98.73 1 179 
A ASN 180 2 98.73 1 180 
A PRO 181 2 98.70 1 181 
A SER 182 2 98.71 1 182 
A TYR 183 2 98.79 1 183 
A ASP 184 2 98.72 1 184 
A LYS 185 2 98.67 1 185 
A ILE 186 2 98.80 1 186 
A PHE 187 2 98.71 1 187 
A SER 188 2 98.39 1 188 
A HIS 189 2 98.67 1 189 
A LEU 190 2 98.71 1 190 
A GLN 191 2 97.93 1 191 
A HIS 192 2 98.46 1 192 
A VAL 193 2 98.69 1 193 
A LYS 194 2 98.69 1 194 
A TYR 195 2 98.67 1 195 
A LYS 196 2 98.25 1 196 
A GLY 197 2 97.74 1 197 
A GLN 198 2 98.61 1 198 
A GLU 199 2 98.74 1 199 
A ALA 200 2 98.69 1 200 
A PHE 201 2 98.68 1 201 
A VAL 202 2 98.70 1 202 
A PRO 203 2 98.52 1 203 
A GLY 204 2 98.65 1 204 
A PHE 205 2 98.80 1 205 
A ASN 206 2 98.69 1 206 
A ILE 207 2 98.82 1 207 
A GLU 208 2 98.65 1 208 
A GLU 209 2 98.62 1 209 
A LEU 210 2 98.85 1 210 
A LEU 211 2 98.83 1 211 
A PRO 212 2 98.62 1 212 
A GLU 213 2 97.38 1 213 
A ARG 214 2 97.62 1 214 
A THR 215 2 98.54 1 215 
A ALA 216 2 98.23 1 216 
A GLU 217 2 98.49 1 217 
A TYR 218 2 98.75 1 218 
A TYR 219 2 98.78 1 219 
A ARG 220 2 98.79 1 220 
A TYR 221 2 98.69 1 221 
A ARG 222 2 98.38 1 222 
A GLY 223 2 98.41 1 223 
A SER 224 2 98.53 1 224 
A LEU 225 2 98.21 1 225 
A THR 226 2 98.54 1 226 
A THR 227 2 97.71 1 227 
A PRO 228 2 97.61 1 228 
A PRO 229 2 97.16 1 229 
A CYS 230 2 98.07 1 230 
A ASN 231 2 97.83 1 231 
A PRO 232 2 97.85 1 232 
A THR 233 2 98.17 1 233 
A VAL 234 2 98.70 1 234 
A LEU 235 2 98.76 1 235 
A TRP 236 2 98.87 1 236 
A THR 237 2 98.93 1 237 
A VAL 238 2 98.92 1 238 
A PHE 239 2 98.87 1 239 
A ARG 240 2 98.54 1 240 
A ASN 241 2 98.59 1 241 
A PRO 242 2 98.74 1 242 
A VAL 243 2 98.85 1 243 
A GLN 244 2 98.84 1 244 
A ILE 245 2 98.84 1 245 
A SER 246 2 98.77 1 246 
A GLN 247 2 98.54 1 247 
A GLU 248 2 98.58 1 248 
A GLN 249 2 98.79 1 249 
A LEU 250 2 98.78 1 250 
A LEU 251 2 98.69 1 251 
A ALA 252 2 98.55 1 252 
A LEU 253 2 98.70 1 253 
A GLU 254 2 98.65 1 254 
A THR 255 2 98.51 1 255 
A ALA 256 2 98.51 1 256 
A LEU 257 2 98.73 1 257 
A TYR 258 2 98.50 1 258 
A CYS 259 2 97.49 1 259 
A THR 260 2 97.18 1 260 
A HIS 261 2 97.39 1 261 
A MET 262 2 97.14 1 262 
A ASP 263 2 96.65 1 263 
A ASP 264 2 96.25 1 264 
A PRO 265 2 96.62 1 265 
A SER 266 2 96.44 1 266 
A PRO 267 2 95.70 1 267 
A ARG 268 2 97.33 1 268 
A GLU 269 2 98.16 1 269 
A MET 270 2 98.57 1 270 
A ILE 271 2 98.59 1 271 
A ASN 272 2 98.55 1 272 
A ASN 273 2 98.64 1 273 
A PHE 274 2 98.75 1 274 
A ARG 275 2 98.73 1 275 
A GLN 276 2 98.59 1 276 
A VAL 277 2 98.71 1 277 
A GLN 278 2 98.58 1 278 
A LYS 279 2 97.75 1 279 
A PHE 280 2 96.97 1 280 
A ASP 281 2 88.44 1 281 
A GLU 282 2 93.38 1 282 
A ARG 283 2 97.37 1 283 
A LEU 284 2 97.76 1 284 
A VAL 285 2 98.62 1 285 
A TYR 286 2 98.54 1 286 
A THR 287 2 98.62 1 287 
A SER 288 2 98.18 1 288 
A PHE 289 2 97.27 1 289 
A SER 290 2 89.38 1 290 
A GLN 291 2 67.62 1 291 
A VAL 292 2 54.66 1 292 
A GLN 293 2 45.92 1 293 
A VAL 294 2 34.55 1 294 
A CYS 295 2 36.64 1 295 
A THR 296 2 35.54 1 296 
A ALA 297 2 40.16 1 297 
A ALA 298 2 45.22 1 298 
A GLY 299 2 50.19 1 299 
A LEU 300 2 57.42 1 300 
A SER 301 2 70.86 1 301 
A LEU 302 2 72.85 1 302 
A GLY 303 2 75.33 1 303 
A ILE 304 2 78.11 1 304 
A ILE 305 2 76.68 1 305 
A LEU 306 2 82.73 1 306 
A SER 307 2 85.27 1 307 
A LEU 308 2 87.01 1 308 
A ALA 309 2 87.18 1 309 
A LEU 310 2 90.23 1 310 
A ALA 311 2 91.21 1 311 
A GLY 312 2 90.33 1 312 
A ILE 313 2 91.99 1 313 
A LEU 314 2 92.43 1 314 
A GLY 315 2 90.60 1 315 
A ILE 316 2 92.10 1 316 
A CYS 317 2 91.70 1 317 
A ILE 318 2 91.58 1 318 
A VAL 319 2 90.86 1 319 
A VAL 320 2 92.02 1 320 
A VAL 321 2 91.07 1 321 
A VAL 322 2 90.73 1 322 
A SER 323 2 88.93 1 323 
A ILE 324 2 89.33 1 324 
A TRP 325 2 87.32 1 325 
A LEU 326 2 87.13 1 326 
A PHE 327 2 83.11 1 327 
A ARG 328 2 82.58 1 328 
A ARG 329 2 79.46 1 329 
A LYS 330 2 73.56 1 330 
A SER 331 2 62.03 1 331 
A ILE 332 2 62.08 1 332 
A LYS 333 2 57.59 1 333 
A LYS 334 2 53.79 1 334 
A GLY 335 2 53.03 1 335 
A ASP 336 2 53.67 1 336 
A ASN 337 2 51.04 1 337 
A LYS 338 2 48.65 1 338 
A GLY 339 2 43.13 1 339 
A VAL 340 2 47.48 1 340 
A ILE 341 2 55.76 1 341 
A TYR 342 2 48.47 1 342 
A LYS 343 2 56.87 1 343 
A PRO 344 2 51.87 1 344 
A ALA 345 2 44.75 1 345 
A THR 346 2 56.84 1 346 
A LYS 347 2 47.55 1 347 
A MET 348 2 53.30 1 348 
A GLU 349 2 54.85 1 349 
A THR 350 2 53.23 1 350 
A GLU 351 2 49.88 1 351 
A ALA 352 2 46.87 1 352 
A HIS 353 2 56.68 1 353 
A ALA 354 2 44.11 1 354 
#
_ma_software_group.group_id    1
_ma_software_group.ordinal_id  1
_ma_software_group.software_id 1
#
_ma_target_entity.data_id   1
_ma_target_entity.entity_id 1
_ma_target_entity.origin    "reference database"
#
_ma_target_entity_instance.asym_id   A
_ma_target_entity_instance.details   .
_ma_target_entity_instance.entity_id 1
#
_ma_target_ref_db_details.db_accession                 O43570
_ma_target_ref_db_details.db_code                      CAH12_HUMAN
_ma_target_ref_db_details.db_name                      UNP
_ma_target_ref_db_details.gene_name                    CA12
_ma_target_ref_db_details.ncbi_taxonomy_id             9606
_ma_target_ref_db_details.organism_scientific          "Homo sapiens"
_ma_target_ref_db_details.seq_db_align_begin           1
_ma_target_ref_db_details.seq_db_align_end             354
_ma_target_ref_db_details.seq_db_isoform               ?
_ma_target_ref_db_details.seq_db_sequence_checksum     9016216BF2CA6C0C
_ma_target_ref_db_details.seq_db_sequence_version_date 1998-06-01
_ma_target_ref_db_details.target_entity_id             1
#
loop_
_ma_template_details.ordinal_id
_ma_template_details.target_asym_id
_ma_template_details.template_auth_asym_id
_ma_template_details.template_data_id
_ma_template_details.template_entity_type
_ma_template_details.template_id
_ma_template_details.template_model_num
_ma_template_details.template_origin
_ma_template_details.template_trans_matrix_id
1 A A 2 polymer 1 1 "reference database" 1 
2 A A 2 polymer 2 1 "reference database" 1 
3 A A 2 polymer 3 1 "reference database" 1 
4 A A 2 polymer 4 1 "reference database" 1 
#
loop_
_ma_template_ref_db_details.db_accession_code
_ma_template_ref_db_details.db_name
_ma_template_ref_db_details.template_id
5CJF PDB 1 
4LU3 PDB 2 
6G7A PDB 3 
6G5L PDB 4 
#
_ma_template_trans_matrix.id               1
_ma_template_trans_matrix.rot_matrix[1][1] 1.0
_ma_template_trans_matrix.rot_matrix[1][2] 0.0
_ma_template_trans_matrix.rot_matrix[1][3] 0.0
_ma_template_trans_matrix.rot_matrix[2][1] 0.0
_ma_template_trans_matrix.rot_matrix[2][2] 1.0
_ma_template_trans_matrix.rot_matrix[2][3] 0.0
_ma_template_trans_matrix.rot_matrix[3][1] 0.0
_ma_template_trans_matrix.rot_matrix[3][2] 0.0
_ma_template_trans_matrix.rot_matrix[3][3] 1.0
_ma_template_trans_matrix.tr_vector[1]     0.0
_ma_template_trans_matrix.tr_vector[2]     0.0
_ma_template_trans_matrix.tr_vector[3]     0.0
#
loop_
_pdbx_audit_revision_details.data_content_type
_pdbx_audit_revision_details.description
_pdbx_audit_revision_details.ordinal
_pdbx_audit_revision_details.provider
_pdbx_audit_revision_details.revision_ordinal
_pdbx_audit_revision_details.type
"Structure model" ?                                                       1 repository 1 "Initial release" 
"Structure model" "Format fixes, new metadata, initial SwissProt release" 2 repository 2 Remediation       
"Structure model" "Format fixes, new metadata, initial UniProt release"   3 repository 3 Remediation       
#
loop_
_pdbx_audit_revision_history.data_content_type
_pdbx_audit_revision_history.major_revision
_pdbx_audit_revision_history.minor_revision
_pdbx_audit_revision_history.ordinal
_pdbx_audit_revision_history.revision_date
"Structure model" 1 0 1 2021-07-01 
"Structure model" 2 0 2 2021-12-09 
"Structure model" 3 0 3 2022-06-01 
#
loop_
_pdbx_data_usage.details
_pdbx_data_usage.id
_pdbx_data_usage.name
_pdbx_data_usage.type
_pdbx_data_usage.url
"Data in this file is available under a CC-BY-4.0 license." 1 CC-BY-4.0 license    https://creativecommons.org/licenses/by/4.0/ 
;ALPHAFOLD DATA, COPYRIGHT (2021) DEEPMIND TECHNOLOGIES LIMITED. THE INFORMATION
PROVIDED IS THEORETICAL MODELLING ONLY AND CAUTION SHOULD BE EXERCISED IN ITS
USE. IT IS PROVIDED "AS-IS" WITHOUT ANY WARRANTY OF ANY KIND, WHETHER EXPRESSED
OR IMPLIED. NO WARRANTY IS GIVEN THAT USE OF THE INFORMATION SHALL NOT INFRINGE
THE RIGHTS OF ANY THIRD PARTY. DISCLAIMER: THE INFORMATION IS NOT INTENDED TO BE
A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT, AND DOES
NOT CONSTITUTE MEDICAL OR OTHER PROFESSIONAL ADVICE. IT IS AVAILABLE FOR
ACADEMIC AND COMMERCIAL PURPOSES, UNDER CC-BY 4.0 LICENCE.
;
2 ?         disclaimer ?                                            
#
_pdbx_database_status.entry_id                      AF-O43570-F1
_pdbx_database_status.recvd_initial_deposition_date 2022-06-01
_pdbx_database_status.status_code                   REL
#
loop_
_pdbx_poly_seq_scheme.asym_id
_pdbx_poly_seq_scheme.auth_seq_num
_pdbx_poly_seq_scheme.entity_id
_pdbx_poly_seq_scheme.hetero
_pdbx_poly_seq_scheme.mon_id
_pdbx_poly_seq_scheme.pdb_ins_code
_pdbx_poly_seq_scheme.pdb_mon_id
_pdbx_poly_seq_scheme.pdb_seq_num
_pdbx_poly_seq_scheme.pdb_strand_id
_pdbx_poly_seq_scheme.seq_id
A 1   1 n MET . MET 1   A 1   
A 2   1 n PRO . PRO 2   A 2   
A 3   1 n ARG . ARG 3   A 3   
A 4   1 n ARG . ARG 4   A 4   
A 5   1 n SER . SER 5   A 5   
A 6   1 n LEU . LEU 6   A 6   
A 7   1 n HIS . HIS 7   A 7   
A 8   1 n ALA . ALA 8   A 8   
A 9   1 n ALA . ALA 9   A 9   
A 10  1 n ALA . ALA 10  A 10  
A 11  1 n VAL . VAL 11  A 11  
A 12  1 n LEU . LEU 12  A 12  
A 13  1 n LEU . LEU 13  A 13  
A 14  1 n LEU . LEU 14  A 14  
A 15  1 n VAL . VAL 15  A 15  
A 16  1 n ILE . ILE 16  A 16  
A 17  1 n LEU . LEU 17  A 17  
A 18  1 n LYS . LYS 18  A 18  
A 19  1 n GLU . GLU 19  A 19  
A 20  1 n GLN . GLN 20  A 20  
A 21  1 n PRO . PRO 21  A 21  
A 22  1 n SER . SER 22  A 22  
A 23  1 n SER . SER 23  A 23  
A 24  1 n PRO . PRO 24  A 24  
A 25  1 n ALA . ALA 25  A 25  
A 26  1 n PRO . PRO 26  A 26  
A 27  1 n VAL . VAL 27  A 27  
A 28  1 n ASN . ASN 28  A 28  
A 29  1 n GLY . GLY 29  A 29  
A 30  1 n SER . SER 30  A 30  
A 31  1 n LYS . LYS 31  A 31  
A 32  1 n TRP . TRP 32  A 32  
A 33  1 n THR . THR 33  A 33  
A 34  1 n TYR . TYR 34  A 34  
A 35  1 n PHE . PHE 35  A 35  
A 36  1 n GLY . GLY 36  A 36  
A 37  1 n PRO . PRO 37  A 37  
A 38  1 n ASP . ASP 38  A 38  
A 39  1 n GLY . GLY 39  A 39  
A 40  1 n GLU . GLU 40  A 40  
A 41  1 n ASN . ASN 41  A 41  
A 42  1 n SER . SER 42  A 42  
A 43  1 n TRP . TRP 43  A 43  
A 44  1 n SER . SER 44  A 44  
A 45  1 n LYS . LYS 45  A 45  
A 46  1 n LYS . LYS 46  A 46  
A 47  1 n TYR . TYR 47  A 47  
A 48  1 n PRO . PRO 48  A 48  
A 49  1 n SER . SER 49  A 49  
A 50  1 n CYS . CYS 50  A 50  
A 51  1 n GLY . GLY 51  A 51  
A 52  1 n GLY . GLY 52  A 52  
A 53  1 n LEU . LEU 53  A 53  
A 54  1 n LEU . LEU 54  A 54  
A 55  1 n GLN . GLN 55  A 55  
A 56  1 n SER . SER 56  A 56  
A 57  1 n PRO . PRO 57  A 57  
A 58  1 n ILE . ILE 58  A 58  
A 59  1 n ASP . ASP 59  A 59  
A 60  1 n LEU . LEU 60  A 60  
A 61  1 n HIS . HIS 61  A 61  
A 62  1 n SER . SER 62  A 62  
A 63  1 n ASP . ASP 63  A 63  
A 64  1 n ILE . ILE 64  A 64  
A 65  1 n LEU . LEU 65  A 65  
A 66  1 n GLN . GLN 66  A 66  
A 67  1 n TYR . TYR 67  A 67  
A 68  1 n ASP . ASP 68  A 68  
A 69  1 n ALA . ALA 69  A 69  
A 70  1 n SER . SER 70  A 70  
A 71  1 n LEU . LEU 71  A 71  
A 72  1 n THR . THR 72  A 72  
A 73  1 n PRO . PRO 73  A 73  
A 74  1 n LEU . LEU 74  A 74  
A 75  1 n GLU . GLU 75  A 75  
A 76  1 n PHE . PHE 76  A 76  
A 77  1 n GLN . GLN 77  A 77  
A 78  1 n GLY . GLY 78  A 78  
A 79  1 n TYR . TYR 79  A 79  
A 80  1 n ASN . ASN 80  A 80  
A 81  1 n LEU . LEU 81  A 81  
A 82  1 n SER . SER 82  A 82  
A 83  1 n ALA . ALA 83  A 83  
A 84  1 n ASN . ASN 84  A 84  
A 85  1 n LYS . LYS 85  A 85  
A 86  1 n GLN . GLN 86  A 86  
A 87  1 n PHE . PHE 87  A 87  
A 88  1 n LEU . LEU 88  A 88  
A 89  1 n LEU . LEU 89  A 89  
A 90  1 n THR . THR 90  A 90  
A 91  1 n ASN . ASN 91  A 91  
A 92  1 n ASN . ASN 92  A 92  
A 93  1 n GLY . GLY 93  A 93  
A 94  1 n HIS . HIS 94  A 94  
A 95  1 n SER . SER 95  A 95  
A 96  1 n VAL . VAL 96  A 96  
A 97  1 n LYS . LYS 97  A 97  
A 98  1 n LEU . LEU 98  A 98  
A 99  1 n ASN . ASN 99  A 99  
A 100 1 n LEU . LEU 100 A 100 
A 101 1 n PRO . PRO 101 A 101 
A 102 1 n SER . SER 102 A 102 
A 103 1 n ASP . ASP 103 A 103 
A 104 1 n MET . MET 104 A 104 
A 105 1 n HIS . HIS 105 A 105 
A 106 1 n ILE . ILE 106 A 106 
A 107 1 n GLN . GLN 107 A 107 
A 108 1 n GLY . GLY 108 A 108 
A 109 1 n LEU . LEU 109 A 109 
A 110 1 n GLN . GLN 110 A 110 
A 111 1 n SER . SER 111 A 111 
A 112 1 n ARG . ARG 112 A 112 
A 113 1 n TYR . TYR 113 A 113 
A 114 1 n SER . SER 114 A 114 
A 115 1 n ALA . ALA 115 A 115 
A 116 1 n THR . THR 116 A 116 
A 117 1 n GLN . GLN 117 A 117 
A 118 1 n LEU . LEU 118 A 118 
A 119 1 n HIS . HIS 119 A 119 
A 120 1 n LEU . LEU 120 A 120 
A 121 1 n HIS . HIS 121 A 121 
A 122 1 n TRP . TRP 122 A 122 
A 123 1 n GLY . GLY 123 A 123 
A 124 1 n ASN . ASN 124 A 124 
A 125 1 n PRO . PRO 125 A 125 
A 126 1 n ASN . ASN 126 A 126 
A 127 1 n ASP . ASP 127 A 127 
A 128 1 n PRO . PRO 128 A 128 
A 129 1 n HIS . HIS 129 A 129 
A 130 1 n GLY . GLY 130 A 130 
A 131 1 n SER . SER 131 A 131 
A 132 1 n GLU . GLU 132 A 132 
A 133 1 n HIS . HIS 133 A 133 
A 134 1 n THR . THR 134 A 134 
A 135 1 n VAL . VAL 135 A 135 
A 136 1 n SER . SER 136 A 136 
A 137 1 n GLY . GLY 137 A 137 
A 138 1 n GLN . GLN 138 A 138 
A 139 1 n HIS . HIS 139 A 139 
A 140 1 n PHE . PHE 140 A 140 
A 141 1 n ALA . ALA 141 A 141 
A 142 1 n ALA . ALA 142 A 142 
A 143 1 n GLU . GLU 143 A 143 
A 144 1 n LEU . LEU 144 A 144 
A 145 1 n HIS . HIS 145 A 145 
A 146 1 n ILE . ILE 146 A 146 
A 147 1 n VAL . VAL 147 A 147 
A 148 1 n HIS . HIS 148 A 148 
A 149 1 n TYR . TYR 149 A 149 
A 150 1 n ASN . ASN 150 A 150 
A 151 1 n SER . SER 151 A 151 
A 152 1 n ASP . ASP 152 A 152 
A 153 1 n LEU . LEU 153 A 153 
A 154 1 n TYR . TYR 154 A 154 
A 155 1 n PRO . PRO 155 A 155 
A 156 1 n ASP . ASP 156 A 156 
A 157 1 n ALA . ALA 157 A 157 
A 158 1 n SER . SER 158 A 158 
A 159 1 n THR . THR 159 A 159 
A 160 1 n ALA . ALA 160 A 160 
A 161 1 n SER . SER 161 A 161 
A 162 1 n ASN . ASN 162 A 162 
A 163 1 n LYS . LYS 163 A 163 
A 164 1 n SER . SER 164 A 164 
A 165 1 n GLU . GLU 165 A 165 
A 166 1 n GLY . GLY 166 A 166 
A 167 1 n LEU . LEU 167 A 167 
A 168 1 n ALA . ALA 168 A 168 
A 169 1 n VAL . VAL 169 A 169 
A 170 1 n LEU . LEU 170 A 170 
A 171 1 n ALA . ALA 171 A 171 
A 172 1 n VAL . VAL 172 A 172 
A 173 1 n LEU . LEU 173 A 173 
A 174 1 n ILE . ILE 174 A 174 
A 175 1 n GLU . GLU 175 A 175 
A 176 1 n MET . MET 176 A 176 
A 177 1 n GLY . GLY 177 A 177 
A 178 1 n SER . SER 178 A 178 
A 179 1 n PHE . PHE 179 A 179 
A 180 1 n ASN . ASN 180 A 180 
A 181 1 n PRO . PRO 181 A 181 
A 182 1 n SER . SER 182 A 182 
A 183 1 n TYR . TYR 183 A 183 
A 184 1 n ASP . ASP 184 A 184 
A 185 1 n LYS . LYS 185 A 185 
A 186 1 n ILE . ILE 186 A 186 
A 187 1 n PHE . PHE 187 A 187 
A 188 1 n SER . SER 188 A 188 
A 189 1 n HIS . HIS 189 A 189 
A 190 1 n LEU . LEU 190 A 190 
A 191 1 n GLN . GLN 191 A 191 
A 192 1 n HIS . HIS 192 A 192 
A 193 1 n VAL . VAL 193 A 193 
A 194 1 n LYS . LYS 194 A 194 
A 195 1 n TYR . TYR 195 A 195 
A 196 1 n LYS . LYS 196 A 196 
A 197 1 n GLY . GLY 197 A 197 
A 198 1 n GLN . GLN 198 A 198 
A 199 1 n GLU . GLU 199 A 199 
A 200 1 n ALA . ALA 200 A 200 
A 201 1 n PHE . PHE 201 A 201 
A 202 1 n VAL . VAL 202 A 202 
A 203 1 n PRO . PRO 203 A 203 
A 204 1 n GLY . GLY 204 A 204 
A 205 1 n PHE . PHE 205 A 205 
A 206 1 n ASN . ASN 206 A 206 
A 207 1 n ILE . ILE 207 A 207 
A 208 1 n GLU . GLU 208 A 208 
A 209 1 n GLU . GLU 209 A 209 
A 210 1 n LEU . LEU 210 A 210 
A 211 1 n LEU . LEU 211 A 211 
A 212 1 n PRO . PRO 212 A 212 
A 213 1 n GLU . GLU 213 A 213 
A 214 1 n ARG . ARG 214 A 214 
A 215 1 n THR . THR 215 A 215 
A 216 1 n ALA . ALA 216 A 216 
A 217 1 n GLU . GLU 217 A 217 
A 218 1 n TYR . TYR 218 A 218 
A 219 1 n TYR . TYR 219 A 219 
A 220 1 n ARG . ARG 220 A 220 
A 221 1 n TYR . TYR 221 A 221 
A 222 1 n ARG . ARG 222 A 222 
A 223 1 n GLY . GLY 223 A 223 
A 224 1 n SER . SER 224 A 224 
A 225 1 n LEU . LEU 225 A 225 
A 226 1 n THR . THR 226 A 226 
A 227 1 n THR . THR 227 A 227 
A 228 1 n PRO . PRO 228 A 228 
A 229 1 n PRO . PRO 229 A 229 
A 230 1 n CYS . CYS 230 A 230 
A 231 1 n ASN . ASN 231 A 231 
A 232 1 n PRO . PRO 232 A 232 
A 233 1 n THR . THR 233 A 233 
A 234 1 n VAL . VAL 234 A 234 
A 235 1 n LEU . LEU 235 A 235 
A 236 1 n TRP . TRP 236 A 236 
A 237 1 n THR . THR 237 A 237 
A 238 1 n VAL . VAL 238 A 238 
A 239 1 n PHE . PHE 239 A 239 
A 240 1 n ARG . ARG 240 A 240 
A 241 1 n ASN . ASN 241 A 241 
A 242 1 n PRO . PRO 242 A 242 
A 243 1 n VAL . VAL 243 A 243 
A 244 1 n GLN . GLN 244 A 244 
A 245 1 n ILE . ILE 245 A 245 
A 246 1 n SER . SER 246 A 246 
A 247 1 n GLN . GLN 247 A 247 
A 248 1 n GLU . GLU 248 A 248 
A 249 1 n GLN . GLN 249 A 249 
A 250 1 n LEU . LEU 250 A 250 
A 251 1 n LEU . LEU 251 A 251 
A 252 1 n ALA . ALA 252 A 252 
A 253 1 n LEU . LEU 253 A 253 
A 254 1 n GLU . GLU 254 A 254 
A 255 1 n THR . THR 255 A 255 
A 256 1 n ALA . ALA 256 A 256 
A 257 1 n LEU . LEU 257 A 257 
A 258 1 n TYR . TYR 258 A 258 
A 259 1 n CYS . CYS 259 A 259 
A 260 1 n THR . THR 260 A 260 
A 261 1 n HIS . HIS 261 A 261 
A 262 1 n MET . MET 262 A 262 
A 263 1 n ASP . ASP 263 A 263 
A 264 1 n ASP . ASP 264 A 264 
A 265 1 n PRO . PRO 265 A 265 
A 266 1 n SER . SER 266 A 266 
A 267 1 n PRO . PRO 267 A 267 
A 268 1 n ARG . ARG 268 A 268 
A 269 1 n GLU . GLU 269 A 269 
A 270 1 n MET . MET 270 A 270 
A 271 1 n ILE . ILE 271 A 271 
A 272 1 n ASN . ASN 272 A 272 
A 273 1 n ASN . ASN 273 A 273 
A 274 1 n PHE . PHE 274 A 274 
A 275 1 n ARG . ARG 275 A 275 
A 276 1 n GLN . GLN 276 A 276 
A 277 1 n VAL . VAL 277 A 277 
A 278 1 n GLN . GLN 278 A 278 
A 279 1 n LYS . LYS 279 A 279 
A 280 1 n PHE . PHE 280 A 280 
A 281 1 n ASP . ASP 281 A 281 
A 282 1 n GLU . GLU 282 A 282 
A 283 1 n ARG . ARG 283 A 283 
A 284 1 n LEU . LEU 284 A 284 
A 285 1 n VAL . VAL 285 A 285 
A 286 1 n TYR . TYR 286 A 286 
A 287 1 n THR . THR 287 A 287 
A 288 1 n SER . SER 288 A 288 
A 289 1 n PHE . PHE 289 A 289 
A 290 1 n SER . SER 290 A 290 
A 291 1 n GLN . GLN 291 A 291 
A 292 1 n VAL . VAL 292 A 292 
A 293 1 n GLN . GLN 293 A 293 
A 294 1 n VAL . VAL 294 A 294 
A 295 1 n CYS . CYS 295 A 295 
A 296 1 n THR . THR 296 A 296 
A 297 1 n ALA . ALA 297 A 297 
A 298 1 n ALA . ALA 298 A 298 
A 299 1 n GLY . GLY 299 A 299 
A 300 1 n LEU . LEU 300 A 300 
A 301 1 n SER . SER 301 A 301 
A 302 1 n LEU . LEU 302 A 302 
A 303 1 n GLY . GLY 303 A 303 
A 304 1 n ILE . ILE 304 A 304 
A 305 1 n ILE . ILE 305 A 305 
A 306 1 n LEU . LEU 306 A 306 
A 307 1 n SER . SER 307 A 307 
A 308 1 n LEU . LEU 308 A 308 
A 309 1 n ALA . ALA 309 A 309 
A 310 1 n LEU . LEU 310 A 310 
A 311 1 n ALA . ALA 311 A 311 
A 312 1 n GLY . GLY 312 A 312 
A 313 1 n ILE . ILE 313 A 313 
A 314 1 n LEU . LEU 314 A 314 
A 315 1 n GLY . GLY 315 A 315 
A 316 1 n ILE . ILE 316 A 316 
A 317 1 n CYS . CYS 317 A 317 
A 318 1 n ILE . ILE 318 A 318 
A 319 1 n VAL . VAL 319 A 319 
A 320 1 n VAL . VAL 320 A 320 
A 321 1 n VAL . VAL 321 A 321 
A 322 1 n VAL . VAL 322 A 322 
A 323 1 n SER . SER 323 A 323 
A 324 1 n ILE . ILE 324 A 324 
A 325 1 n TRP . TRP 325 A 325 
A 326 1 n LEU . LEU 326 A 326 
A 327 1 n PHE . PHE 327 A 327 
A 328 1 n ARG . ARG 328 A 328 
A 329 1 n ARG . ARG 329 A 329 
A 330 1 n LYS . LYS 330 A 330 
A 331 1 n SER . SER 331 A 331 
A 332 1 n ILE . ILE 332 A 332 
A 333 1 n LYS . LYS 333 A 333 
A 334 1 n LYS . LYS 334 A 334 
A 335 1 n GLY . GLY 335 A 335 
A 336 1 n ASP . ASP 336 A 336 
A 337 1 n ASN . ASN 337 A 337 
A 338 1 n LYS . LYS 338 A 338 
A 339 1 n GLY . GLY 339 A 339 
A 340 1 n VAL . VAL 340 A 340 
A 341 1 n ILE . ILE 341 A 341 
A 342 1 n TYR . TYR 342 A 342 
A 343 1 n LYS . LYS 343 A 343 
A 344 1 n PRO . PRO 344 A 344 
A 345 1 n ALA . ALA 345 A 345 
A 346 1 n THR . THR 346 A 346 
A 347 1 n LYS . LYS 347 A 347 
A 348 1 n MET . MET 348 A 348 
A 349 1 n GLU . GLU 349 A 349 
A 350 1 n THR . THR 350 A 350 
A 351 1 n GLU . GLU 351 A 351 
A 352 1 n ALA . ALA 352 A 352 
A 353 1 n HIS . HIS 353 A 353 
A 354 1 n ALA . ALA 354 A 354 
#
loop_
_software.classification
_software.date
_software.description
_software.name
_software.pdbx_ordinal
_software.type
_software.version
other ? "Structure prediction" AlphaFold 1 package v2.0 
other ? "Secondary structure"  dssp      2 library 4    
#
_struct_asym.entity_id 1
_struct_asym.id        A
#
loop_
_struct_conf.beg_auth_asym_id
_struct_conf.beg_auth_comp_id
_struct_conf.beg_auth_seq_id
_struct_conf.beg_label_asym_id
_struct_conf.beg_label_comp_id
_struct_conf.beg_label_seq_id
_struct_conf.conf_type_id
_struct_conf.end_auth_asym_id
_struct_conf.end_auth_comp_id
_struct_conf.end_auth_seq_id
_struct_conf.end_label_asym_id
_struct_conf.end_label_comp_id
_struct_conf.end_label_seq_id
_struct_conf.id
_struct_conf.pdbx_beg_PDB_ins_code
_struct_conf.pdbx_end_PDB_ins_code
A SER 23  A SER 23  HELX_LH_PP_P A PRO 26  A PRO 26  HELX_LH_PP_P1 ? ? 
A GLY 29  A GLY 29  TURN_TY1_P   A SER 30  A SER 30  TURN_TY1_P1   ? ? 
A TYR 34  A TYR 34  BEND         A GLY 36  A GLY 36  BEND1         ? ? 
A PRO 37  A PRO 37  TURN_TY1_P   A ASP 38  A ASP 38  TURN_TY1_P2   ? ? 
A GLY 39  A GLY 39  BEND         A GLY 39  A GLY 39  BEND2         ? ? 
A GLU 40  A GLU 40  HELX_RH_3T_P A LYS 45  A LYS 45  HELX_RH_3T_P1 ? ? 
A LYS 46  A LYS 46  TURN_TY1_P   A LYS 46  A LYS 46  TURN_TY1_P3   ? ? 
A PRO 48  A PRO 48  HELX_RH_3T_P A GLY 51  A GLY 51  HELX_RH_3T_P2 ? ? 
A GLY 52  A GLY 52  BEND         A LEU 54  A LEU 54  BEND3         ? ? 
A SER 56  A SER 56  BEND         A SER 56  A SER 56  BEND4         ? ? 
A ASP 59  A ASP 59  STRN         A LEU 60  A LEU 60  STRN1         ? ? 
A SER 62  A SER 62  HELX_RH_3T_P A ILE 64  A ILE 64  HELX_RH_3T_P3 ? ? 
A LEU 65  A LEU 65  STRN         A TYR 67  A TYR 67  STRN2         ? ? 
A ALA 69  A ALA 69  TURN_TY1_P   A SER 70  A SER 70  TURN_TY1_P4   ? ? 
A THR 72  A THR 72  HELX_LH_PP_P A LEU 74  A LEU 74  HELX_LH_PP_P2 ? ? 
A GLU 75  A GLU 75  STRN         A GLN 77  A GLN 77  STRN3         ? ? 
A GLY 78  A GLY 78  TURN_TY1_P   A GLY 78  A GLY 78  TURN_TY1_P5   ? ? 
A ASN 80  A ASN 80  STRN         A ASN 80  A ASN 80  STRN4         ? ? 
A ALA 83  A ALA 83  TURN_TY1_P   A ASN 84  A ASN 84  TURN_TY1_P6   ? ? 
A LYS 85  A LYS 85  BEND         A LYS 85  A LYS 85  BEND5         ? ? 
A GLN 86  A GLN 86  STRN         A ASN 91  A ASN 91  STRN5         ? ? 
A GLY 93  A GLY 93  BEND         A SER 95  A SER 95  BEND6         ? ? 
A VAL 96  A VAL 96  STRN         A ASN 99  A ASN 99  STRN6         ? ? 
A SER 102 A SER 102 TURN_TY1_P   A ASP 103 A ASP 103 TURN_TY1_P7   ? ? 
A HIS 105 A HIS 105 STRN         A GLN 107 A GLN 107 STRN7         ? ? 
A GLY 108 A GLY 108 BEND         A SER 111 A SER 111 BEND7         ? ? 
A TYR 113 A TYR 113 STRN         A TRP 122 A TRP 122 STRN8         ? ? 
A ASN 124 A ASN 124 STRN         A ASN 124 A ASN 124 STRN9         ? ? 
A PRO 125 A PRO 125 TURN_TY1_P   A ASN 126 A ASN 126 TURN_TY1_P8   ? ? 
A ASP 127 A ASP 127 STRN         A ASP 127 A ASP 127 STRN10        ? ? 
A GLU 132 A GLU 132 BEND         A HIS 133 A HIS 133 BEND8         ? ? 
A THR 134 A THR 134 STRN         A VAL 135 A VAL 135 STRN11        ? ? 
A SER 136 A SER 136 TURN_TY1_P   A GLY 137 A GLY 137 TURN_TY1_P9   ? ? 
A GLN 138 A GLN 138 STRN         A HIS 139 A HIS 139 STRN12        ? ? 
A PHE 140 A PHE 140 HELX_LH_PP_P A PHE 140 A PHE 140 HELX_LH_PP_P3 ? ? 
A ALA 141 A ALA 141 BEND         A ALA 141 A ALA 141 BEND9         ? ? 
A ALA 142 A ALA 142 STRN         A ASN 150 A ASN 150 STRN13        ? ? 
A SER 151 A SER 151 TURN_TY1_P   A LEU 153 A LEU 153 TURN_TY1_P10  ? ? 
A PRO 155 A PRO 155 BEND         A ASP 156 A ASP 156 BEND10        ? ? 
A ALA 157 A ALA 157 HELX_RH_AL_P A ALA 160 A ALA 160 HELX_RH_AL_P1 ? ? 
A SER 161 A SER 161 TURN_TY1_P   A ASN 162 A ASN 162 TURN_TY1_P11  ? ? 
A LYS 163 A LYS 163 BEND         A LYS 163 A LYS 163 BEND11        ? ? 
A SER 164 A SER 164 TURN_TY1_P   A GLU 165 A GLU 165 TURN_TY1_P12  ? ? 
A LEU 167 A LEU 167 STRN         A MET 176 A MET 176 STRN14        ? ? 
A SER 178 A SER 178 BEND         A SER 178 A SER 178 BEND12        ? ? 
A PRO 181 A PRO 181 HELX_RH_AL_P A PHE 187 A PHE 187 HELX_RH_AL_P2 ? ? 
A SER 188 A SER 188 TURN_TY1_P   A HIS 189 A HIS 189 TURN_TY1_P13  ? ? 
A LEU 190 A LEU 190 HELX_RH_3T_P A VAL 193 A VAL 193 HELX_RH_3T_P4 ? ? 
A TYR 195 A TYR 195 BEND         A TYR 195 A TYR 195 BEND13        ? ? 
A LYS 196 A LYS 196 TURN_TY1_P   A GLY 197 A GLY 197 TURN_TY1_P14  ? ? 
A GLU 199 A GLU 199 STRN         A PRO 203 A PRO 203 STRN15        ? ? 
A ASN 206 A ASN 206 STRN         A ASN 206 A ASN 206 STRN16        ? ? 
A ILE 207 A ILE 207 HELX_RH_3T_P A LEU 210 A LEU 210 HELX_RH_3T_P5 ? ? 
A LEU 211 A LEU 211 BEND         A LEU 211 A LEU 211 BEND14        ? ? 
A PRO 212 A PRO 212 HELX_LH_PP_P A PRO 212 A PRO 212 HELX_LH_PP_P4 ? ? 
A GLU 213 A GLU 213 BEND         A GLU 213 A GLU 213 BEND15        ? ? 
A THR 215 A THR 215 TURN_TY1_P   A ALA 216 A ALA 216 TURN_TY1_P15  ? ? 
A TYR 218 A TYR 218 STRN         A GLY 223 A GLY 223 STRN17        ? ? 
A THR 226 A THR 226 BEND         A THR 227 A THR 227 BEND16        ? ? 
A PRO 228 A PRO 228 TURN_TY1_P   A PRO 229 A PRO 229 TURN_TY1_P16  ? ? 
A PRO 232 A PRO 232 BEND         A PRO 232 A PRO 232 BEND17        ? ? 
A VAL 234 A VAL 234 STRN         A PHE 239 A PHE 239 STRN18        ? ? 
A ARG 240 A ARG 240 BEND         A ASN 241 A ASN 241 BEND18        ? ? 
A PRO 242 A PRO 242 HELX_LH_PP_P A PRO 242 A PRO 242 HELX_LH_PP_P5 ? ? 
A VAL 243 A VAL 243 STRN         A ILE 245 A ILE 245 STRN19        ? ? 
A GLN 247 A GLN 247 HELX_RH_AL_P A THR 255 A THR 255 HELX_RH_AL_P3 ? ? 
A ALA 256 A ALA 256 BEND         A ALA 256 A ALA 256 BEND19        ? ? 
A TYR 258 A TYR 258 STRN         A TYR 258 A TYR 258 STRN20        ? ? 
A CYS 259 A CYS 259 BEND         A THR 260 A THR 260 BEND20        ? ? 
A MET 262 A MET 262 TURN_TY1_P   A ASP 263 A ASP 263 TURN_TY1_P17  ? ? 
A PRO 265 A PRO 265 BEND         A SER 266 A SER 266 BEND21        ? ? 
A GLU 269 A GLU 269 STRN         A GLU 269 A GLU 269 STRN21        ? ? 
A ARG 275 A ARG 275 HELX_LH_PP_P A LYS 279 A LYS 279 HELX_LH_PP_P6 ? ? 
A ASP 281 A ASP 281 TURN_TY1_P   A GLU 282 A GLU 282 TURN_TY1_P18  ? ? 
A VAL 285 A VAL 285 STRN         A THR 287 A THR 287 STRN22        ? ? 
A SER 288 A SER 288 BEND         A PHE 289 A PHE 289 BEND22        ? ? 
A ALA 297 A ALA 297 BEND         A GLY 299 A GLY 299 BEND23        ? ? 
A LEU 302 A LEU 302 HELX_RH_AL_P A GLY 335 A GLY 335 HELX_RH_AL_P4 ? ? 
A ASP 336 A ASP 336 TURN_TY1_P   A ASN 337 A ASN 337 TURN_TY1_P19  ? ? 
A LYS 338 A LYS 338 BEND         A LYS 338 A LYS 338 BEND24        ? ? 
A TYR 342 A TYR 342 HELX_LH_PP_P A PRO 344 A PRO 344 HELX_LH_PP_P7 ? ? 
A GLU 349 A GLU 349 HELX_LH_PP_P A GLU 351 A GLU 351 HELX_LH_PP_P8 ? ? 
#
loop_
_struct_conf_type.criteria
_struct_conf_type.id
DSSP HELX_LH_PP_P 
DSSP TURN_TY1_P   
DSSP BEND         
DSSP HELX_RH_3T_P 
DSSP STRN         
DSSP HELX_RH_AL_P 
#
_struct_ref.db_code                  CAH12_HUMAN
_struct_ref.db_name                  UNP
_struct_ref.entity_id                1
_struct_ref.id                       1
_struct_ref.pdbx_align_begin         1
_struct_ref.pdbx_align_end           354
_struct_ref.pdbx_db_accession        O43570
_struct_ref.pdbx_db_isoform          ?
_struct_ref.pdbx_seq_one_letter_code 
;MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYN
LSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTA
SNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFR
NPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQVQVCTAAGLSLGIILSLALAGILGICIVV
VVSIWLFRRKSIKKGDNKGVIYKPATKMETEAHA
;
#
_struct_ref_seq.align_id                    1
_struct_ref_seq.db_align_beg                1
_struct_ref_seq.db_align_end                354
_struct_ref_seq.pdbx_PDB_id_code            AF-O43570-F1
_struct_ref_seq.pdbx_auth_seq_align_beg     1
_struct_ref_seq.pdbx_auth_seq_align_end     354
_struct_ref_seq.pdbx_db_accession           O43570
_struct_ref_seq.pdbx_db_align_beg_ins_code  ?
_struct_ref_seq.pdbx_db_align_end_ins_code  ?
_struct_ref_seq.pdbx_seq_align_beg_ins_code ?
_struct_ref_seq.pdbx_seq_align_end_ins_code ?
_struct_ref_seq.pdbx_strand_id              A
_struct_ref_seq.ref_id                      1
_struct_ref_seq.seq_align_beg               1
_struct_ref_seq.seq_align_end               354
#
loop_
_atom_site.group_PDB
_atom_site.id
_atom_site.type_symbol
_atom_site.label_atom_id
_atom_site.label_alt_id
_atom_site.label_comp_id
_atom_site.label_asym_id
_atom_site.label_entity_id
_atom_site.label_seq_id
_atom_site.pdbx_PDB_ins_code
_atom_site.Cartn_x
_atom_site.Cartn_y
_atom_site.Cartn_z
_atom_site.occupancy
_atom_site.B_iso_or_equiv
_atom_site.pdbx_formal_charge
_atom_site.auth_seq_id
_atom_site.auth_comp_id
_atom_site.auth_asym_id
_atom_site.auth_atom_id
_atom_site.pdbx_PDB_model_num
_atom_site.pdbx_sifts_xref_db_acc
_atom_site.pdbx_sifts_xref_db_name
_atom_site.pdbx_sifts_xref_db_num
_atom_site.pdbx_sifts_xref_db_res
ATOM 1    N N   . MET A 1 1   ? 58.458  67.367  -18.964 1.0 38.46 ? 1   MET A N   1 O43570 UNP 1   M 
ATOM 2    C CA  . MET A 1 1   ? 57.794  67.750  -17.692 1.0 38.46 ? 1   MET A CA  1 O43570 UNP 1   M 
ATOM 3    C C   . MET A 1 1   ? 56.442  68.371  -18.047 1.0 38.46 ? 1   MET A C   1 O43570 UNP 1   M 
ATOM 4    C CB  . MET A 1 1   ? 58.626  68.818  -16.950 1.0 38.46 ? 1   MET A CB  1 O43570 UNP 1   M 
ATOM 5    O O   . MET A 1 1   ? 56.471  69.134  -19.002 1.0 38.46 ? 1   MET A O   1 O43570 UNP 1   M 
ATOM 6    C CG  . MET A 1 1   ? 59.986  68.346  -16.418 1.0 38.46 ? 1   MET A CG  1 O43570 UNP 1   M 
ATOM 7    S SD  . MET A 1 1   ? 60.867  69.674  -15.555 1.0 38.46 ? 1   MET A SD  1 O43570 UNP 1   M 
ATOM 8    C CE  . MET A 1 1   ? 62.303  68.789  -14.885 1.0 38.46 ? 1   MET A CE  1 O43570 UNP 1   M 
ATOM 9    N N   . PRO A 1 2   ? 55.295  68.138  -17.373 1.0 50.96 ? 2   PRO A N   1 O43570 UNP 2   P 
ATOM 10   C CA  . PRO A 1 2   ? 54.945  67.192  -16.308 1.0 50.96 ? 2   PRO A CA  1 O43570 UNP 2   P 
ATOM 11   C C   . PRO A 1 2   ? 53.736  66.260  -16.633 1.0 50.96 ? 2   PRO A C   1 O43570 UNP 2   P 
ATOM 12   C CB  . PRO A 1 2   ? 54.579  68.130  -15.150 1.0 50.96 ? 2   PRO A CB  1 O43570 UNP 2   P 
ATOM 13   O O   . PRO A 1 2   ? 52.926  66.526  -17.511 1.0 50.96 ? 2   PRO A O   1 O43570 UNP 2   P 
ATOM 14   C CG  . PRO A 1 2   ? 53.914  69.329  -15.840 1.0 50.96 ? 2   PRO A CG  1 O43570 UNP 2   P 
ATOM 15   C CD  . PRO A 1 2   ? 54.315  69.217  -17.311 1.0 50.96 ? 2   PRO A CD  1 O43570 UNP 2   P 
ATOM 16   N N   . ARG A 1 3   ? 53.654  65.168  -15.856 1.0 42.22 ? 3   ARG A N   1 O43570 UNP 3   R 
ATOM 17   C CA  . ARG A 1 3   ? 52.479  64.421  -15.343 1.0 42.22 ? 3   ARG A CA  1 O43570 UNP 3   R 
ATOM 18   C C   . ARG A 1 3   ? 51.211  64.299  -16.212 1.0 42.22 ? 3   ARG A C   1 O43570 UNP 3   R 
ATOM 19   C CB  . ARG A 1 3   ? 52.090  65.024  -13.974 1.0 42.22 ? 3   ARG A CB  1 O43570 UNP 3   R 
ATOM 20   O O   . ARG A 1 3   ? 50.385  65.206  -16.228 1.0 42.22 ? 3   ARG A O   1 O43570 UNP 3   R 
ATOM 21   C CG  . ARG A 1 3   ? 53.161  64.827  -12.889 1.0 42.22 ? 3   ARG A CG  1 O43570 UNP 3   R 
ATOM 22   C CD  . ARG A 1 3   ? 52.726  65.465  -11.563 1.0 42.22 ? 3   ARG A CD  1 O43570 UNP 3   R 
ATOM 23   N NE  . ARG A 1 3   ? 53.688  65.171  -10.482 1.0 42.22 ? 3   ARG A NE  1 O43570 UNP 3   R 
ATOM 24   N NH1 . ARG A 1 3   ? 52.642  66.349  -8.803  1.0 42.22 ? 3   ARG A NH1 1 O43570 UNP 3   R 
ATOM 25   N NH2 . ARG A 1 3   ? 54.502  65.207  -8.353  1.0 42.22 ? 3   ARG A NH2 1 O43570 UNP 3   R 
ATOM 26   C CZ  . ARG A 1 3   ? 53.606  65.578  -9.224  1.0 42.22 ? 3   ARG A CZ  1 O43570 UNP 3   R 
ATOM 27   N N   . ARG A 1 4   ? 50.936  63.080  -16.703 1.0 47.96 ? 4   ARG A N   1 O43570 UNP 4   R 
ATOM 28   C CA  . ARG A 1 4   ? 49.563  62.555  -16.811 1.0 47.96 ? 4   ARG A CA  1 O43570 UNP 4   R 
ATOM 29   C C   . ARG A 1 4   ? 49.478  61.105  -16.332 1.0 47.96 ? 4   ARG A C   1 O43570 UNP 4   R 
ATOM 30   C CB  . ARG A 1 4   ? 48.960  62.737  -18.214 1.0 47.96 ? 4   ARG A CB  1 O43570 UNP 4   R 
ATOM 31   O O   . ARG A 1 4   ? 50.280  60.258  -16.706 1.0 47.96 ? 4   ARG A O   1 O43570 UNP 4   R 
ATOM 32   C CG  . ARG A 1 4   ? 48.433  64.170  -18.396 1.0 47.96 ? 4   ARG A CG  1 O43570 UNP 4   R 
ATOM 33   C CD  . ARG A 1 4   ? 47.586  64.327  -19.658 1.0 47.96 ? 4   ARG A CD  1 O43570 UNP 4   R 
ATOM 34   N NE  . ARG A 1 4   ? 46.932  65.650  -19.684 1.0 47.96 ? 4   ARG A NE  1 O43570 UNP 4   R 
ATOM 35   N NH1 . ARG A 1 4   ? 45.855  65.405  -21.695 1.0 47.96 ? 4   ARG A NH1 1 O43570 UNP 4   R 
ATOM 36   N NH2 . ARG A 1 4   ? 45.552  67.269  -20.509 1.0 47.96 ? 4   ARG A NH2 1 O43570 UNP 4   R 
ATOM 37   C CZ  . ARG A 1 4   ? 46.120  66.101  -20.625 1.0 47.96 ? 4   ARG A CZ  1 O43570 UNP 4   R 
ATOM 38   N N   . SER A 1 5   ? 48.509  60.925  -15.444 1.0 43.39 ? 5   SER A N   1 O43570 UNP 5   S 
ATOM 39   C CA  . SER A 1 5   ? 48.025  59.708  -14.800 1.0 43.39 ? 5   SER A CA  1 O43570 UNP 5   S 
ATOM 40   C C   . SER A 1 5   ? 47.683  58.611  -15.815 1.0 43.39 ? 5   SER A C   1 O43570 UNP 5   S 
ATOM 41   C CB  . SER A 1 5   ? 46.757  60.135  -14.040 1.0 43.39 ? 5   SER A CB  1 O43570 UNP 5   S 
ATOM 42   O O   . SER A 1 5   ? 46.969  58.874  -16.781 1.0 43.39 ? 5   SER A O   1 O43570 UNP 5   S 
ATOM 43   O OG  . SER A 1 5   ? 46.032  59.026  -13.583 1.0 43.39 ? 5   SER A OG  1 O43570 UNP 5   S 
ATOM 44   N N   . LEU A 1 6   ? 48.175  57.394  -15.568 1.0 47.35 ? 6   LEU A N   1 O43570 UNP 6   L 
ATOM 45   C CA  . LEU A 1 6   ? 47.723  56.160  -16.209 1.0 47.35 ? 6   LEU A CA  1 O43570 UNP 6   L 
ATOM 46   C C   . LEU A 1 6   ? 46.844  55.409  -15.202 1.0 47.35 ? 6   LEU A C   1 O43570 UNP 6   L 
ATOM 47   C CB  . LEU A 1 6   ? 48.939  55.337  -16.683 1.0 47.35 ? 6   LEU A CB  1 O43570 UNP 6   L 
ATOM 48   O O   . LEU A 1 6   ? 47.335  54.763  -14.278 1.0 47.35 ? 6   LEU A O   1 O43570 UNP 6   L 
ATOM 49   C CG  . LEU A 1 6   ? 49.438  55.750  -18.082 1.0 47.35 ? 6   LEU A CG  1 O43570 UNP 6   L 
ATOM 50   C CD1 . LEU A 1 6   ? 50.913  55.390  -18.260 1.0 47.35 ? 6   LEU A CD1 1 O43570 UNP 6   L 
ATOM 51   C CD2 . LEU A 1 6   ? 48.641  55.052  -19.187 1.0 47.35 ? 6   LEU A CD2 1 O43570 UNP 6   L 
ATOM 52   N N   . HIS A 1 7   ? 45.533  55.553  -15.375 1.0 42.59 ? 7   HIS A N   1 O43570 UNP 7   H 
ATOM 53   C CA  . HIS A 1 7   ? 44.543  54.588  -14.909 1.0 42.59 ? 7   HIS A CA  1 O43570 UNP 7   H 
ATOM 54   C C   . HIS A 1 7   ? 44.467  53.410  -15.893 1.0 42.59 ? 7   HIS A C   1 O43570 UNP 7   H 
ATOM 55   C CB  . HIS A 1 7   ? 43.170  55.280  -14.791 1.0 42.59 ? 7   HIS A CB  1 O43570 UNP 7   H 
ATOM 56   O O   . HIS A 1 7   ? 44.841  53.566  -17.053 1.0 42.59 ? 7   HIS A O   1 O43570 UNP 7   H 
ATOM 57   C CG  . HIS A 1 7   ? 42.998  56.123  -13.553 1.0 42.59 ? 7   HIS A CG  1 O43570 UNP 7   H 
ATOM 58   C CD2 . HIS A 1 7   ? 42.407  57.356  -13.477 1.0 42.59 ? 7   HIS A CD2 1 O43570 UNP 7   H 
ATOM 59   N ND1 . HIS A 1 7   ? 43.316  55.749  -12.266 1.0 42.59 ? 7   HIS A ND1 1 O43570 UNP 7   H 
ATOM 60   C CE1 . HIS A 1 7   ? 42.937  56.735  -11.439 1.0 42.59 ? 7   HIS A CE1 1 O43570 UNP 7   H 
ATOM 61   N NE2 . HIS A 1 7   ? 42.393  57.745  -12.133 1.0 42.59 ? 7   HIS A NE2 1 O43570 UNP 7   H 
ATOM 62   N N   . ALA A 1 8   ? 43.872  52.305  -15.426 1.0 44.58 ? 8   ALA A N   1 O43570 UNP 8   A 
ATOM 63   C CA  . ALA A 1 8   ? 43.561  51.047  -16.123 1.0 44.58 ? 8   ALA A CA  1 O43570 UNP 8   A 
ATOM 64   C C   . ALA A 1 8   ? 44.645  49.960  -15.968 1.0 44.58 ? 8   ALA A C   1 O43570 UNP 8   A 
ATOM 65   C CB  . ALA A 1 8   ? 43.159  51.290  -17.589 1.0 44.58 ? 8   ALA A CB  1 O43570 UNP 8   A 
ATOM 66   O O   . ALA A 1 8   ? 45.818  50.207  -16.197 1.0 44.58 ? 8   ALA A O   1 O43570 UNP 8   A 
ATOM 67   N N   . ALA A 1 9   ? 44.348  48.721  -15.588 1.0 41.98 ? 9   ALA A N   1 O43570 UNP 9   A 
ATOM 68   C CA  . ALA A 1 9   ? 43.091  48.084  -15.223 1.0 41.98 ? 9   ALA A CA  1 O43570 UNP 9   A 
ATOM 69   C C   . ALA A 1 9   ? 43.422  46.890  -14.313 1.0 41.98 ? 9   ALA A C   1 O43570 UNP 9   A 
ATOM 70   C CB  . ALA A 1 9   ? 42.386  47.605  -16.500 1.0 41.98 ? 9   ALA A CB  1 O43570 UNP 9   A 
ATOM 71   O O   . ALA A 1 9   ? 44.353  46.135  -14.593 1.0 41.98 ? 9   ALA A O   1 O43570 UNP 9   A 
ATOM 72   N N   . ALA A 1 10  ? 42.668  46.722  -13.226 1.0 44.40 ? 10  ALA A N   1 O43570 UNP 10  A 
ATOM 73   C CA  . ALA A 1 10  ? 42.715  45.516  -12.413 1.0 44.40 ? 10  ALA A CA  1 O43570 UNP 10  A 
ATOM 74   C C   . ALA A 1 10  ? 41.961  44.402  -13.151 1.0 44.40 ? 10  ALA A C   1 O43570 UNP 10  A 
ATOM 75   C CB  . ALA A 1 10  ? 42.131  45.815  -11.026 1.0 44.40 ? 10  ALA A CB  1 O43570 UNP 10  A 
ATOM 76   O O   . ALA A 1 10  ? 40.757  44.499  -13.384 1.0 44.40 ? 10  ALA A O   1 O43570 UNP 10  A 
ATOM 77   N N   . VAL A 1 11  ? 42.693  43.364  -13.547 1.0 43.27 ? 11  VAL A N   1 O43570 UNP 11  V 
ATOM 78   C CA  . VAL A 1 11  ? 42.154  42.137  -14.136 1.0 43.27 ? 11  VAL A CA  1 O43570 UNP 11  V 
ATOM 79   C C   . VAL A 1 11  ? 41.495  41.332  -13.016 1.0 43.27 ? 11  VAL A C   1 O43570 UNP 11  V 
ATOM 80   C CB  . VAL A 1 11  ? 43.282  41.355  -14.845 1.0 43.27 ? 11  VAL A CB  1 O43570 UNP 11  V 
ATOM 81   O O   . VAL A 1 11  ? 42.175  40.716  -12.199 1.0 43.27 ? 11  VAL A O   1 O43570 UNP 11  V 
ATOM 82   C CG1 . VAL A 1 11  ? 42.806  40.008  -15.400 1.0 43.27 ? 11  VAL A CG1 1 O43570 UNP 11  V 
ATOM 83   C CG2 . VAL A 1 11  ? 43.847  42.170  -16.020 1.0 43.27 ? 11  VAL A CG2 1 O43570 UNP 11  V 
ATOM 84   N N   . LEU A 1 12  ? 40.163  41.371  -12.954 1.0 42.30 ? 12  LEU A N   1 O43570 UNP 12  L 
ATOM 85   C CA  . LEU A 1 12  ? 39.366  40.522  -12.073 1.0 42.30 ? 12  LEU A CA  1 O43570 UNP 12  L 
ATOM 86   C C   . LEU A 1 12  ? 39.164  39.167  -12.768 1.0 42.30 ? 12  LEU A C   1 O43570 UNP 12  L 
ATOM 87   C CB  . LEU A 1 12  ? 38.046  41.245  -11.728 1.0 42.30 ? 12  LEU A CB  1 O43570 UNP 12  L 
ATOM 88   O O   . LEU A 1 12  ? 38.401  39.057  -13.727 1.0 42.30 ? 12  LEU A O   1 O43570 UNP 12  L 
ATOM 89   C CG  . LEU A 1 12  ? 37.287  40.631  -10.535 1.0 42.30 ? 12  LEU A CG  1 O43570 UNP 12  L 
ATOM 90   C CD1 . LEU A 1 12  ? 37.966  40.965  -9.202  1.0 42.30 ? 12  LEU A CD1 1 O43570 UNP 12  L 
ATOM 91   C CD2 . LEU A 1 12  ? 35.861  41.182  -10.480 1.0 42.30 ? 12  LEU A CD2 1 O43570 UNP 12  L 
ATOM 92   N N   . LEU A 1 13  ? 39.887  38.146  -12.303 1.0 39.06 ? 13  LEU A N   1 O43570 UNP 13  L 
ATOM 93   C CA  . LEU A 1 13  ? 39.702  36.756  -12.718 1.0 39.06 ? 13  LEU A CA  1 O43570 UNP 13  L 
ATOM 94   C C   . LEU A 1 13  ? 38.340  36.256  -12.197 1.0 39.06 ? 13  LEU A C   1 O43570 UNP 13  L 
ATOM 95   C CB  . LEU A 1 13  ? 40.873  35.880  -12.199 1.0 39.06 ? 13  LEU A CB  1 O43570 UNP 13  L 
ATOM 96   O O   . LEU A 1 13  ? 38.194  35.920  -11.024 1.0 39.06 ? 13  LEU A O   1 O43570 UNP 13  L 
ATOM 97   C CG  . LEU A 1 13  ? 41.724  35.226  -13.305 1.0 39.06 ? 13  LEU A CG  1 O43570 UNP 13  L 
ATOM 98   C CD1 . LEU A 1 13  ? 42.907  36.114  -13.696 1.0 39.06 ? 13  LEU A CD1 1 O43570 UNP 13  L 
ATOM 99   C CD2 . LEU A 1 13  ? 42.274  33.880  -12.833 1.0 39.06 ? 13  LEU A CD2 1 O43570 UNP 13  L 
ATOM 100  N N   . LEU A 1 14  ? 37.338  36.210  -13.074 1.0 44.78 ? 14  LEU A N   1 O43570 UNP 14  L 
ATOM 101  C CA  . LEU A 1 14  ? 36.078  35.508  -12.834 1.0 44.78 ? 14  LEU A CA  1 O43570 UNP 14  L 
ATOM 102  C C   . LEU A 1 14  ? 36.305  34.006  -13.038 1.0 44.78 ? 14  LEU A C   1 O43570 UNP 14  L 
ATOM 103  C CB  . LEU A 1 14  ? 34.982  36.086  -13.752 1.0 44.78 ? 14  LEU A CB  1 O43570 UNP 14  L 
ATOM 104  O O   . LEU A 1 14  ? 36.411  33.519  -14.164 1.0 44.78 ? 14  LEU A O   1 O43570 UNP 14  L 
ATOM 105  C CG  . LEU A 1 14  ? 34.192  37.225  -13.076 1.0 44.78 ? 14  LEU A CG  1 O43570 UNP 14  L 
ATOM 106  C CD1 . LEU A 1 14  ? 33.686  38.229  -14.109 1.0 44.78 ? 14  LEU A CD1 1 O43570 UNP 14  L 
ATOM 107  C CD2 . LEU A 1 14  ? 32.986  36.667  -12.315 1.0 44.78 ? 14  LEU A CD2 1 O43570 UNP 14  L 
ATOM 108  N N   . VAL A 1 15  ? 36.388  33.273  -11.928 1.0 48.21 ? 15  VAL A N   1 O43570 UNP 15  V 
ATOM 109  C CA  . VAL A 1 15  ? 36.322  31.810  -11.902 1.0 48.21 ? 15  VAL A CA  1 O43570 UNP 15  V 
ATOM 110  C C   . VAL A 1 15  ? 34.890  31.408  -12.251 1.0 48.21 ? 15  VAL A C   1 O43570 UNP 15  V 
ATOM 111  C CB  . VAL A 1 15  ? 36.768  31.260  -10.529 1.0 48.21 ? 15  VAL A CB  1 O43570 UNP 15  V 
ATOM 112  O O   . VAL A 1 15  ? 33.992  31.450  -11.414 1.0 48.21 ? 15  VAL A O   1 O43570 UNP 15  V 
ATOM 113  C CG1 . VAL A 1 15  ? 36.607  29.737  -10.425 1.0 48.21 ? 15  VAL A CG1 1 O43570 UNP 15  V 
ATOM 114  C CG2 . VAL A 1 15  ? 38.249  31.588  -10.281 1.0 48.21 ? 15  VAL A CG2 1 O43570 UNP 15  V 
ATOM 115  N N   . ILE A 1 16  ? 34.672  31.043  -13.513 1.0 46.99 ? 16  ILE A N   1 O43570 UNP 16  I 
ATOM 116  C CA  . ILE A 1 16  ? 33.432  30.414  -13.969 1.0 46.99 ? 16  ILE A CA  1 O43570 UNP 16  I 
ATOM 117  C C   . ILE A 1 16  ? 33.476  28.956  -13.504 1.0 46.99 ? 16  ILE A C   1 O43570 UNP 16  I 
ATOM 118  C CB  . ILE A 1 16  ? 33.245  30.575  -15.499 1.0 46.99 ? 16  ILE A CB  1 O43570 UNP 16  I 
ATOM 119  O O   . ILE A 1 16  ? 34.015  28.082  -14.186 1.0 46.99 ? 16  ILE A O   1 O43570 UNP 16  I 
ATOM 120  C CG1 . ILE A 1 16  ? 33.234  32.074  -15.890 1.0 46.99 ? 16  ILE A CG1 1 O43570 UNP 16  I 
ATOM 121  C CG2 . ILE A 1 16  ? 31.939  29.891  -15.958 1.0 46.99 ? 16  ILE A CG2 1 O43570 UNP 16  I 
ATOM 122  C CD1 . ILE A 1 16  ? 33.152  32.339  -17.399 1.0 46.99 ? 16  ILE A CD1 1 O43570 UNP 16  I 
ATOM 123  N N   . LEU A 1 17  ? 32.919  28.696  -12.320 1.0 48.82 ? 17  LEU A N   1 O43570 UNP 17  L 
ATOM 124  C CA  . LEU A 1 17  ? 32.464  27.363  -11.942 1.0 48.82 ? 17  LEU A CA  1 O43570 UNP 17  L 
ATOM 125  C C   . LEU A 1 17  ? 31.338  26.990  -12.910 1.0 48.82 ? 17  LEU A C   1 O43570 UNP 17  L 
ATOM 126  C CB  . LEU A 1 17  ? 32.010  27.364  -10.466 1.0 48.82 ? 17  LEU A CB  1 O43570 UNP 17  L 
ATOM 127  O O   . LEU A 1 17  ? 30.208  27.451  -12.783 1.0 48.82 ? 17  LEU A O   1 O43570 UNP 17  L 
ATOM 128  C CG  . LEU A 1 17  ? 33.162  27.050  -9.490  1.0 48.82 ? 17  LEU A CG  1 O43570 UNP 17  L 
ATOM 129  C CD1 . LEU A 1 17  ? 32.953  27.746  -8.148  1.0 48.82 ? 17  LEU A CD1 1 O43570 UNP 17  L 
ATOM 130  C CD2 . LEU A 1 17  ? 33.271  25.543  -9.241  1.0 48.82 ? 17  LEU A CD2 1 O43570 UNP 17  L 
ATOM 131  N N   . LYS A 1 18  ? 31.673  26.190  -13.927 1.0 43.88 ? 18  LYS A N   1 O43570 UNP 18  K 
ATOM 132  C CA  . LYS A 1 18  ? 30.683  25.447  -14.706 1.0 43.88 ? 18  LYS A CA  1 O43570 UNP 18  K 
ATOM 133  C C   . LYS A 1 18  ? 30.005  24.467  -13.750 1.0 43.88 ? 18  LYS A C   1 O43570 UNP 18  K 
ATOM 134  C CB  . LYS A 1 18  ? 31.347  24.710  -15.886 1.0 43.88 ? 18  LYS A CB  1 O43570 UNP 18  K 
ATOM 135  O O   . LYS A 1 18  ? 30.484  23.349  -13.575 1.0 43.88 ? 18  LYS A O   1 O43570 UNP 18  K 
ATOM 136  C CG  . LYS A 1 18  ? 31.552  25.587  -17.128 1.0 43.88 ? 18  LYS A CG  1 O43570 UNP 18  K 
ATOM 137  C CD  . LYS A 1 18  ? 32.196  24.758  -18.250 1.0 43.88 ? 18  LYS A CD  1 O43570 UNP 18  K 
ATOM 138  C CE  . LYS A 1 18  ? 32.216  25.541  -19.567 1.0 43.88 ? 18  LYS A CE  1 O43570 UNP 18  K 
ATOM 139  N NZ  . LYS A 1 18  ? 32.821  24.743  -20.663 1.0 43.88 ? 18  LYS A NZ  1 O43570 UNP 18  K 
ATOM 140  N N   . GLU A 1 19  ? 28.912  24.894  -13.128 1.0 47.27 ? 19  GLU A N   1 O43570 UNP 19  E 
ATOM 141  C CA  . GLU A 1 19  ? 27.908  23.976  -12.603 1.0 47.27 ? 19  GLU A CA  1 O43570 UNP 19  E 
ATOM 142  C C   . GLU A 1 19  ? 27.471  23.096  -13.774 1.0 47.27 ? 19  GLU A C   1 O43570 UNP 19  E 
ATOM 143  C CB  . GLU A 1 19  ? 26.726  24.743  -11.986 1.0 47.27 ? 19  GLU A CB  1 O43570 UNP 19  E 
ATOM 144  O O   . GLU A 1 19  ? 26.891  23.565  -14.756 1.0 47.27 ? 19  GLU A O   1 O43570 UNP 19  E 
ATOM 145  C CG  . GLU A 1 19  ? 27.079  25.236  -10.573 1.0 47.27 ? 19  GLU A CG  1 O43570 UNP 19  E 
ATOM 146  C CD  . GLU A 1 19  ? 25.968  26.066  -9.912  1.0 47.27 ? 19  GLU A CD  1 O43570 UNP 19  E 
ATOM 147  O OE1 . GLU A 1 19  ? 25.965  26.110  -8.662  1.0 47.27 ? 19  GLU A OE1 1 O43570 UNP 19  E 
ATOM 148  O OE2 . GLU A 1 19  ? 25.161  26.672  -10.652 1.0 47.27 ? 19  GLU A OE2 1 O43570 UNP 19  E 
ATOM 149  N N   . GLN A 1 20  ? 27.862  21.821  -13.725 1.0 40.26 ? 20  GLN A N   1 O43570 UNP 20  Q 
ATOM 150  C CA  . GLN A 1 20  ? 27.318  20.835  -14.639 1.0 40.26 ? 20  GLN A CA  1 O43570 UNP 20  Q 
ATOM 151  C C   . GLN A 1 20  ? 25.805  20.819  -14.420 1.0 40.26 ? 20  GLN A C   1 O43570 UNP 20  Q 
ATOM 152  C CB  . GLN A 1 20  ? 27.894  19.437  -14.368 1.0 40.26 ? 20  GLN A CB  1 O43570 UNP 20  Q 
ATOM 153  O O   . GLN A 1 20  ? 25.379  20.589  -13.286 1.0 40.26 ? 20  GLN A O   1 O43570 UNP 20  Q 
ATOM 154  C CG  . GLN A 1 20  ? 29.320  19.257  -14.897 1.0 40.26 ? 20  GLN A CG  1 O43570 UNP 20  Q 
ATOM 155  C CD  . GLN A 1 20  ? 29.759  17.799  -14.793 1.0 40.26 ? 20  GLN A CD  1 O43570 UNP 20  Q 
ATOM 156  N NE2 . GLN A 1 20  ? 30.161  17.170  -15.877 1.0 40.26 ? 20  GLN A NE2 1 O43570 UNP 20  Q 
ATOM 157  O OE1 . GLN A 1 20  ? 29.742  17.184  -13.743 1.0 40.26 ? 20  GLN A OE1 1 O43570 UNP 20  Q 
ATOM 158  N N   . PRO A 1 21  ? 24.985  21.027  -15.463 1.0 38.70 ? 21  PRO A N   1 O43570 UNP 21  P 
ATOM 159  C CA  . PRO A 1 21  ? 23.570  20.751  -15.341 1.0 38.70 ? 21  PRO A CA  1 O43570 UNP 21  P 
ATOM 160  C C   . PRO A 1 21  ? 23.462  19.259  -15.036 1.0 38.70 ? 21  PRO A C   1 O43570 UNP 21  P 
ATOM 161  C CB  . PRO A 1 21  ? 22.947  21.175  -16.673 1.0 38.70 ? 21  PRO A CB  1 O43570 UNP 21  P 
ATOM 162  O O   . PRO A 1 21  ? 23.856  18.418  -15.851 1.0 38.70 ? 21  PRO A O   1 O43570 UNP 21  P 
ATOM 163  C CG  . PRO A 1 21  ? 24.095  21.059  -17.675 1.0 38.70 ? 21  PRO A CG  1 O43570 UNP 21  P 
ATOM 164  C CD  . PRO A 1 21  ? 25.346  21.328  -16.840 1.0 38.70 ? 21  PRO A CD  1 O43570 UNP 21  P 
ATOM 165  N N   . SER A 1 22  ? 22.995  18.931  -13.832 1.0 38.49 ? 22  SER A N   1 O43570 UNP 22  S 
ATOM 166  C CA  . SER A 1 22  ? 22.576  17.583  -13.488 1.0 38.49 ? 22  SER A CA  1 O43570 UNP 22  S 
ATOM 167  C C   . SER A 1 22  ? 21.488  17.201  -14.486 1.0 38.49 ? 22  SER A C   1 O43570 UNP 22  S 
ATOM 168  C CB  . SER A 1 22  ? 22.097  17.516  -12.029 1.0 38.49 ? 22  SER A CB  1 O43570 UNP 22  S 
ATOM 169  O O   . SER A 1 22  ? 20.338  17.620  -14.387 1.0 38.49 ? 22  SER A O   1 O43570 UNP 22  S 
ATOM 170  O OG  . SER A 1 22  ? 21.297  18.632  -11.689 1.0 38.49 ? 22  SER A OG  1 O43570 UNP 22  S 
ATOM 171  N N   . SER A 1 23  ? 21.877  16.451  -15.519 1.0 37.16 ? 23  SER A N   1 O43570 UNP 23  S 
ATOM 172  C CA  . SER A 1 23  ? 20.906  15.819  -16.402 1.0 37.16 ? 23  SER A CA  1 O43570 UNP 23  S 
ATOM 173  C C   . SER A 1 23  ? 19.999  14.966  -15.521 1.0 37.16 ? 23  SER A C   1 O43570 UNP 23  S 
ATOM 174  C CB  . SER A 1 23  ? 21.581  14.934  -17.451 1.0 37.16 ? 23  SER A CB  1 O43570 UNP 23  S 
ATOM 175  O O   . SER A 1 23  ? 20.525  14.183  -14.719 1.0 37.16 ? 23  SER A O   1 O43570 UNP 23  S 
ATOM 176  O OG  . SER A 1 23  ? 22.090  15.740  -18.492 1.0 37.16 ? 23  SER A OG  1 O43570 UNP 23  S 
ATOM 177  N N   . PRO A 1 24  ? 18.665  15.085  -15.633 1.0 40.03 ? 24  PRO A N   1 O43570 UNP 24  P 
ATOM 178  C CA  . PRO A 1 24  ? 17.796  14.103  -15.018 1.0 40.03 ? 24  PRO A CA  1 O43570 UNP 24  P 
ATOM 179  C C   . PRO A 1 24  ? 18.222  12.746  -15.577 1.0 40.03 ? 24  PRO A C   1 O43570 UNP 24  P 
ATOM 180  C CB  . PRO A 1 24  ? 16.368  14.513  -15.385 1.0 40.03 ? 24  PRO A CB  1 O43570 UNP 24  P 
ATOM 181  O O   . PRO A 1 24  ? 18.397  12.591  -16.790 1.0 40.03 ? 24  PRO A O   1 O43570 UNP 24  P 
ATOM 182  C CG  . PRO A 1 24  ? 16.539  15.302  -16.682 1.0 40.03 ? 24  PRO A CG  1 O43570 UNP 24  P 
ATOM 183  C CD  . PRO A 1 24  ? 17.920  15.938  -16.546 1.0 40.03 ? 24  PRO A CD  1 O43570 UNP 24  P 
ATOM 184  N N   . ALA A 1 25  ? 18.476  11.790  -14.681 1.0 34.99 ? 25  ALA A N   1 O43570 UNP 25  A 
ATOM 185  C CA  . ALA A 1 25  ? 18.758  10.421  -15.078 1.0 34.99 ? 25  ALA A CA  1 O43570 UNP 25  A 
ATOM 186  C C   . ALA A 1 25  ? 17.689  9.989   -16.097 1.0 34.99 ? 25  ALA A C   1 O43570 UNP 25  A 
ATOM 187  C CB  . ALA A 1 25  ? 18.764  9.526   -13.834 1.0 34.99 ? 25  ALA A CB  1 O43570 UNP 25  A 
ATOM 188  O O   . ALA A 1 25  ? 16.513  10.322  -15.905 1.0 34.99 ? 25  ALA A O   1 O43570 UNP 25  A 
ATOM 189  N N   . PRO A 1 26  ? 18.071  9.295   -17.184 1.0 28.77 ? 26  PRO A N   1 O43570 UNP 26  P 
ATOM 190  C CA  . PRO A 1 26  ? 17.111  8.872   -18.187 1.0 28.77 ? 26  PRO A CA  1 O43570 UNP 26  P 
ATOM 191  C C   . PRO A 1 26  ? 15.994  8.114   -17.477 1.0 28.77 ? 26  PRO A C   1 O43570 UNP 26  P 
ATOM 192  C CB  . PRO A 1 26  ? 17.891  8.003   -19.180 1.0 28.77 ? 26  PRO A CB  1 O43570 UNP 26  P 
ATOM 193  O O   . PRO A 1 26  ? 16.268  7.257   -16.630 1.0 28.77 ? 26  PRO A O   1 O43570 UNP 26  P 
ATOM 194  C CG  . PRO A 1 26  ? 19.099  7.524   -18.375 1.0 28.77 ? 26  PRO A CG  1 O43570 UNP 26  P 
ATOM 195  C CD  . PRO A 1 26  ? 19.363  8.675   -17.408 1.0 28.77 ? 26  PRO A CD  1 O43570 UNP 26  P 
ATOM 196  N N   . VAL A 1 27  ? 14.748  8.462   -17.803 1.0 36.01 ? 27  VAL A N   1 O43570 UNP 27  V 
ATOM 197  C CA  . VAL A 1 27  ? 13.544  7.755   -17.364 1.0 36.01 ? 27  VAL A CA  1 O43570 UNP 27  V 
ATOM 198  C C   . VAL A 1 27  ? 13.637  6.335   -17.916 1.0 36.01 ? 27  VAL A C   1 O43570 UNP 27  V 
ATOM 199  C CB  . VAL A 1 27  ? 12.262  8.484   -17.833 1.0 36.01 ? 27  VAL A CB  1 O43570 UNP 27  V 
ATOM 200  O O   . VAL A 1 27  ? 13.102  6.011   -18.969 1.0 36.01 ? 27  VAL A O   1 O43570 UNP 27  V 
ATOM 201  C CG1 . VAL A 1 27  ? 10.989  7.783   -17.335 1.0 36.01 ? 27  VAL A CG1 1 O43570 UNP 27  V 
ATOM 202  C CG2 . VAL A 1 27  ? 12.222  9.929   -17.316 1.0 36.01 ? 27  VAL A CG2 1 O43570 UNP 27  V 
ATOM 203  N N   . ASN A 1 28  ? 14.368  5.469   -17.219 1.0 32.01 ? 28  ASN A N   1 O43570 UNP 28  N 
ATOM 204  C CA  . ASN A 1 28  ? 14.355  4.032   -17.430 1.0 32.01 ? 28  ASN A CA  1 O43570 UNP 28  N 
ATOM 205  C C   . ASN A 1 28  ? 13.060  3.535   -16.767 1.0 32.01 ? 28  ASN A C   1 O43570 UNP 28  N 
ATOM 206  C CB  . ASN A 1 28  ? 15.687  3.433   -16.917 1.0 32.01 ? 28  ASN A CB  1 O43570 UNP 28  N 
ATOM 207  O O   . ASN A 1 28  ? 13.064  2.966   -15.672 1.0 32.01 ? 28  ASN A O   1 O43570 UNP 28  N 
ATOM 208  C CG  . ASN A 1 28  ? 16.341  2.471   -17.896 1.0 32.01 ? 28  ASN A CG  1 O43570 UNP 28  N 
ATOM 209  N ND2 . ASN A 1 28  ? 17.533  2.010   -17.598 1.0 32.01 ? 28  ASN A ND2 1 O43570 UNP 28  N 
ATOM 210  O OD1 . ASN A 1 28  ? 15.839  2.127   -18.945 1.0 32.01 ? 28  ASN A OD1 1 O43570 UNP 28  N 
ATOM 211  N N   . GLY A 1 29  ? 11.940  3.932   -17.378 1.0 37.52 ? 29  GLY A N   1 O43570 UNP 29  G 
ATOM 212  C CA  . GLY A 1 29  ? 10.588  3.787   -16.864 1.0 37.52 ? 29  GLY A CA  1 O43570 UNP 29  G 
ATOM 213  C C   . GLY A 1 29  ? 10.235  2.317   -16.688 1.0 37.52 ? 29  GLY A C   1 O43570 UNP 29  G 
ATOM 214  O O   . GLY A 1 29  ? 10.238  1.553   -17.651 1.0 37.52 ? 29  GLY A O   1 O43570 UNP 29  G 
ATOM 215  N N   . SER A 1 30  ? 9.925   1.939   -15.445 1.0 57.67 ? 30  SER A N   1 O43570 UNP 30  S 
ATOM 216  C CA  . SER A 1 30  ? 9.345   0.641   -15.064 1.0 57.67 ? 30  SER A CA  1 O43570 UNP 30  S 
ATOM 217  C C   . SER A 1 30  ? 10.266  -0.585  -15.147 1.0 57.67 ? 30  SER A C   1 O43570 UNP 30  S 
ATOM 218  C CB  . SER A 1 30  ? 8.061   0.388   -15.862 1.0 57.67 ? 30  SER A CB  1 O43570 UNP 30  S 
ATOM 219  O O   . SER A 1 30  ? 9.836   -1.629  -15.633 1.0 57.67 ? 30  SER A O   1 O43570 UNP 30  S 
ATOM 220  O OG  . SER A 1 30  ? 7.176   1.484   -15.825 1.0 57.67 ? 30  SER A OG  1 O43570 UNP 30  S 
ATOM 221  N N   . LYS A 1 31  ? 11.525  -0.520  -14.681 1.0 83.36 ? 31  LYS A N   1 O43570 UNP 31  K 
ATOM 222  C CA  . LYS A 1 31  ? 12.341  -1.754  -14.601 1.0 83.36 ? 31  LYS A CA  1 O43570 UNP 31  K 
ATOM 223  C C   . LYS A 1 31  ? 11.891  -2.702  -13.476 1.0 83.36 ? 31  LYS A C   1 O43570 UNP 31  K 
ATOM 224  C CB  . LYS A 1 31  ? 13.853  -1.455  -14.544 1.0 83.36 ? 31  LYS A CB  1 O43570 UNP 31  K 
ATOM 225  O O   . LYS A 1 31  ? 12.040  -3.911  -13.603 1.0 83.36 ? 31  LYS A O   1 O43570 UNP 31  K 
ATOM 226  C CG  . LYS A 1 31  ? 14.609  -2.757  -14.872 1.0 83.36 ? 31  LYS A CG  1 O43570 UNP 31  K 
ATOM 227  C CD  . LYS A 1 31  ? 16.135  -2.705  -14.856 1.0 83.36 ? 31  LYS A CD  1 O43570 UNP 31  K 
ATOM 228  C CE  . LYS A 1 31  ? 16.554  -4.134  -15.231 1.0 83.36 ? 31  LYS A CE  1 O43570 UNP 31  K 
ATOM 229  N NZ  . LYS A 1 31  ? 17.982  -4.446  -15.005 1.0 83.36 ? 31  LYS A NZ  1 O43570 UNP 31  K 
ATOM 230  N N   . TRP A 1 32  ? 11.396  -2.168  -12.364 1.0 96.07 ? 32  TRP A N   1 O43570 UNP 32  W 
ATOM 231  C CA  . TRP A 1 32  ? 11.033  -2.982  -11.205 1.0 96.07 ? 32  TRP A CA  1 O43570 UNP 32  W 
ATOM 232  C C   . TRP A 1 32  ? 9.777   -3.820  -11.471 1.0 96.07 ? 32  TRP A C   1 O43570 UNP 32  W 
ATOM 233  C CB  . TRP A 1 32  ? 10.893  -2.077  -9.981  1.0 96.07 ? 32  TRP A CB  1 O43570 UNP 32  W 
ATOM 234  O O   . TRP A 1 32  ? 8.954   -3.491  -12.318 1.0 96.07 ? 32  TRP A O   1 O43570 UNP 32  W 
ATOM 235  C CG  . TRP A 1 32  ? 9.784   -1.078  -10.057 1.0 96.07 ? 32  TRP A CG  1 O43570 UNP 32  W 
ATOM 236  C CD1 . TRP A 1 32  ? 9.884   0.218   -10.434 1.0 96.07 ? 32  TRP A CD1 1 O43570 UNP 32  W 
ATOM 237  C CD2 . TRP A 1 32  ? 8.389   -1.280  -9.684  1.0 96.07 ? 32  TRP A CD2 1 O43570 UNP 32  W 
ATOM 238  C CE2 . TRP A 1 32  ? 7.686   -0.054  -9.876  1.0 96.07 ? 32  TRP A CE2 1 O43570 UNP 32  W 
ATOM 239  C CE3 . TRP A 1 32  ? 7.666   -2.362  -9.145  1.0 96.07 ? 32  TRP A CE3 1 O43570 UNP 32  W 
ATOM 240  N NE1 . TRP A 1 32  ? 8.644   0.821   -10.338 1.0 96.07 ? 32  TRP A NE1 1 O43570 UNP 32  W 
ATOM 241  C CH2 . TRP A 1 32  ? 5.639   -1.005  -9.019  1.0 96.07 ? 32  TRP A CH2 1 O43570 UNP 32  W 
ATOM 242  C CZ2 . TRP A 1 32  ? 6.330   0.093   -9.557  1.0 96.07 ? 32  TRP A CZ2 1 O43570 UNP 32  W 
ATOM 243  C CZ3 . TRP A 1 32  ? 6.310   -2.222  -8.813  1.0 96.07 ? 32  TRP A CZ3 1 O43570 UNP 32  W 
ATOM 244  N N   . THR A 1 33  ? 9.637   -4.924  -10.752 1.0 96.87 ? 33  THR A N   1 O43570 UNP 33  T 
ATOM 245  C CA  . THR A 1 33  ? 8.503   -5.853  -10.858 1.0 96.87 ? 33  THR A CA  1 O43570 UNP 33  T 
ATOM 246  C C   . THR A 1 33  ? 8.141   -6.371  -9.468  1.0 96.87 ? 33  THR A C   1 O43570 UNP 33  T 
ATOM 247  C CB  . THR A 1 33  ? 8.856   -7.029  -11.785 1.0 96.87 ? 33  THR A CB  1 O43570 UNP 33  T 
ATOM 248  O O   . THR A 1 33  ? 8.888   -6.132  -8.521  1.0 96.87 ? 33  THR A O   1 O43570 UNP 33  T 
ATOM 249  C CG2 . THR A 1 33  ? 9.155   -6.625  -13.230 1.0 96.87 ? 33  THR A CG2 1 O43570 UNP 33  T 
ATOM 250  O OG1 . THR A 1 33  ? 10.005  -7.672  -11.315 1.0 96.87 ? 33  THR A OG1 1 O43570 UNP 33  T 
ATOM 251  N N   . TYR A 1 34  ? 7.030   -7.095  -9.337  1.0 97.22 ? 34  TYR A N   1 O43570 UNP 34  Y 
ATOM 252  C CA  . TYR A 1 34  ? 6.688   -7.814  -8.101  1.0 97.22 ? 34  TYR A CA  1 O43570 UNP 34  Y 
ATOM 253  C C   . TYR A 1 34  ? 7.292   -9.229  -8.050  1.0 97.22 ? 34  TYR A C   1 O43570 UNP 34  Y 
ATOM 254  C CB  . TYR A 1 34  ? 5.164   -7.821  -7.937  1.0 97.22 ? 34  TYR A CB  1 O43570 UNP 34  Y 
ATOM 255  O O   . TYR A 1 34  ? 7.441   -9.802  -6.978  1.0 97.22 ? 34  TYR A O   1 O43570 UNP 34  Y 
ATOM 256  C CG  . TYR A 1 34  ? 4.609   -6.453  -7.589  1.0 97.22 ? 34  TYR A CG  1 O43570 UNP 34  Y 
ATOM 257  C CD1 . TYR A 1 34  ? 4.529   -6.069  -6.237  1.0 97.22 ? 34  TYR A CD1 1 O43570 UNP 34  Y 
ATOM 258  C CD2 . TYR A 1 34  ? 4.163   -5.572  -8.596  1.0 97.22 ? 34  TYR A CD2 1 O43570 UNP 34  Y 
ATOM 259  C CE1 . TYR A 1 34  ? 4.001   -4.814  -5.885  1.0 97.22 ? 34  TYR A CE1 1 O43570 UNP 34  Y 
ATOM 260  C CE2 . TYR A 1 34  ? 3.619   -4.320  -8.244  1.0 97.22 ? 34  TYR A CE2 1 O43570 UNP 34  Y 
ATOM 261  O OH  . TYR A 1 34  ? 3.000   -2.743  -6.548  1.0 97.22 ? 34  TYR A OH  1 O43570 UNP 34  Y 
ATOM 262  C CZ  . TYR A 1 34  ? 3.538   -3.940  -6.887  1.0 97.22 ? 34  TYR A CZ  1 O43570 UNP 34  Y 
ATOM 263  N N   . PHE A 1 35  ? 7.727   -9.779  -9.190  1.0 94.33 ? 35  PHE A N   1 O43570 UNP 35  F 
ATOM 264  C CA  . PHE A 1 35  ? 8.194   -11.163 -9.307  1.0 94.33 ? 35  PHE A CA  1 O43570 UNP 35  F 
ATOM 265  C C   . PHE A 1 35  ? 9.539   -11.291 -10.028 1.0 94.33 ? 35  PHE A C   1 O43570 UNP 35  F 
ATOM 266  C CB  . PHE A 1 35  ? 7.123   -12.000 -10.013 1.0 94.33 ? 35  PHE A CB  1 O43570 UNP 35  F 
ATOM 267  O O   . PHE A 1 35  ? 9.914   -10.472 -10.860 1.0 94.33 ? 35  PHE A O   1 O43570 UNP 35  F 
ATOM 268  C CG  . PHE A 1 35  ? 6.790   -11.551 -11.424 1.0 94.33 ? 35  PHE A CG  1 O43570 UNP 35  F 
ATOM 269  C CD1 . PHE A 1 35  ? 5.772   -10.602 -11.621 1.0 94.33 ? 35  PHE A CD1 1 O43570 UNP 35  F 
ATOM 270  C CD2 . PHE A 1 35  ? 7.438   -12.127 -12.535 1.0 94.33 ? 35  PHE A CD2 1 O43570 UNP 35  F 
ATOM 271  C CE1 . PHE A 1 35  ? 5.359   -10.270 -12.918 1.0 94.33 ? 35  PHE A CE1 1 O43570 UNP 35  F 
ATOM 272  C CE2 . PHE A 1 35  ? 7.018   -11.805 -13.838 1.0 94.33 ? 35  PHE A CE2 1 O43570 UNP 35  F 
ATOM 273  C CZ  . PHE A 1 35  ? 5.950   -10.904 -14.018 1.0 94.33 ? 35  PHE A CZ  1 O43570 UNP 35  F 
ATOM 274  N N   . GLY A 1 36  ? 10.255  -12.383 -9.760  1.0 94.03 ? 36  GLY A N   1 O43570 UNP 36  G 
ATOM 275  C CA  . GLY A 1 36  ? 11.521  -12.680 -10.427 1.0 94.03 ? 36  GLY A CA  1 O43570 UNP 36  G 
ATOM 276  C C   . GLY A 1 36  ? 12.693  -11.803 -9.950  1.0 94.03 ? 36  GLY A C   1 O43570 UNP 36  G 
ATOM 277  O O   . GLY A 1 36  ? 12.674  -11.283 -8.832  1.0 94.03 ? 36  GLY A O   1 O43570 UNP 36  G 
ATOM 278  N N   . PRO A 1 37  ? 13.761  -11.659 -10.758 1.0 94.76 ? 37  PRO A N   1 O43570 UNP 37  P 
ATOM 279  C CA  . PRO A 1 37  ? 15.024  -11.057 -10.318 1.0 94.76 ? 37  PRO A CA  1 O43570 UNP 37  P 
ATOM 280  C C   . PRO A 1 37  ? 14.932  -9.554  -10.012 1.0 94.76 ? 37  PRO A C   1 O43570 UNP 37  P 
ATOM 281  C CB  . PRO A 1 37  ? 16.014  -11.342 -11.453 1.0 94.76 ? 37  PRO A CB  1 O43570 UNP 37  P 
ATOM 282  O O   . PRO A 1 37  ? 15.691  -9.061  -9.173  1.0 94.76 ? 37  PRO A O   1 O43570 UNP 37  P 
ATOM 283  C CG  . PRO A 1 37  ? 15.125  -11.477 -12.689 1.0 94.76 ? 37  PRO A CG  1 O43570 UNP 37  P 
ATOM 284  C CD  . PRO A 1 37  ? 13.867  -12.134 -12.130 1.0 94.76 ? 37  PRO A CD  1 O43570 UNP 37  P 
ATOM 285  N N   . ASP A 1 38  ? 13.999  -8.844  -10.652 1.0 95.82 ? 38  ASP A N   1 O43570 UNP 38  D 
ATOM 286  C CA  . ASP A 1 38  ? 13.690  -7.429  -10.411 1.0 95.82 ? 38  ASP A CA  1 O43570 UNP 38  D 
ATOM 287  C C   . ASP A 1 38  ? 12.481  -7.261  -9.449  1.0 95.82 ? 38  ASP A C   1 O43570 UNP 38  D 
ATOM 288  C CB  . ASP A 1 38  ? 13.525  -6.690  -11.762 1.0 95.82 ? 38  ASP A CB  1 O43570 UNP 38  D 
ATOM 289  O O   . ASP A 1 38  ? 11.849  -6.202  -9.427  1.0 95.82 ? 38  ASP A O   1 O43570 UNP 38  D 
ATOM 290  C CG  . ASP A 1 38  ? 14.824  -6.530  -12.584 1.0 95.82 ? 38  ASP A CG  1 O43570 UNP 38  D 
ATOM 291  O OD1 . ASP A 1 38  ? 15.839  -6.018  -12.047 1.0 95.82 ? 38  ASP A OD1 1 O43570 UNP 38  D 
ATOM 292  O OD2 . ASP A 1 38  ? 14.824  -6.817  -13.802 1.0 95.82 ? 38  ASP A OD2 1 O43570 UNP 38  D 
ATOM 293  N N   . GLY A 1 39  ? 12.144  -8.314  -8.685  1.0 96.96 ? 39  GLY A N   1 O43570 UNP 39  G 
ATOM 294  C CA  . GLY A 1 39  ? 11.082  -8.363  -7.669  1.0 96.96 ? 39  GLY A CA  1 O43570 UNP 39  G 
ATOM 295  C C   . GLY A 1 39  ? 11.356  -7.506  -6.425  1.0 96.96 ? 39  GLY A C   1 O43570 UNP 39  G 
ATOM 296  O O   . GLY A 1 39  ? 12.434  -6.917  -6.295  1.0 96.96 ? 39  GLY A O   1 O43570 UNP 39  G 
ATOM 297  N N   . GLU A 1 40  ? 10.417  -7.474  -5.472  1.0 97.66 ? 40  GLU A N   1 O43570 UNP 40  E 
ATOM 298  C CA  . GLU A 1 40  ? 10.477  -6.567  -4.309  1.0 97.66 ? 40  GLU A CA  1 O43570 UNP 40  E 
ATOM 299  C C   . GLU A 1 40  ? 11.740  -6.697  -3.446  1.0 97.66 ? 40  GLU A C   1 O43570 UNP 40  E 
ATOM 300  C CB  . GLU A 1 40  ? 9.193   -6.650  -3.478  1.0 97.66 ? 40  GLU A CB  1 O43570 UNP 40  E 
ATOM 301  O O   . GLU A 1 40  ? 12.338  -5.692  -3.055  1.0 97.66 ? 40  GLU A O   1 O43570 UNP 40  E 
ATOM 302  C CG  . GLU A 1 40  ? 8.997   -7.994  -2.770  1.0 97.66 ? 40  GLU A CG  1 O43570 UNP 40  E 
ATOM 303  C CD  . GLU A 1 40  ? 7.777   -7.895  -1.863  1.0 97.66 ? 40  GLU A CD  1 O43570 UNP 40  E 
ATOM 304  O OE1 . GLU A 1 40  ? 6.681   -8.258  -2.327  1.0 97.66 ? 40  GLU A OE1 1 O43570 UNP 40  E 
ATOM 305  O OE2 . GLU A 1 40  ? 7.939   -7.385  -0.733  1.0 97.66 ? 40  GLU A OE2 1 O43570 UNP 40  E 
ATOM 306  N N   . ASN A 1 41  ? 12.248  -7.921  -3.277  1.0 97.43 ? 41  ASN A N   1 O43570 UNP 41  N 
ATOM 307  C CA  . ASN A 1 41  ? 13.497  -8.197  -2.557  1.0 97.43 ? 41  ASN A CA  1 O43570 UNP 41  N 
ATOM 308  C C   . ASN A 1 41  ? 14.739  -7.565  -3.220  1.0 97.43 ? 41  ASN A C   1 O43570 UNP 41  N 
ATOM 309  C CB  . ASN A 1 41  ? 13.652  -9.724  -2.436  1.0 97.43 ? 41  ASN A CB  1 O43570 UNP 41  N 
ATOM 310  O O   . ASN A 1 41  ? 15.792  -7.441  -2.594  1.0 97.43 ? 41  ASN A O   1 O43570 UNP 41  N 
ATOM 311  C CG  . ASN A 1 41  ? 12.628  -10.340 -1.498  1.0 97.43 ? 41  ASN A CG  1 O43570 UNP 41  N 
ATOM 312  N ND2 . ASN A 1 41  ? 12.248  -11.578 -1.705  1.0 97.43 ? 41  ASN A ND2 1 O43570 UNP 41  N 
ATOM 313  O OD1 . ASN A 1 41  ? 12.174  -9.728  -0.555  1.0 97.43 ? 41  ASN A OD1 1 O43570 UNP 41  N 
ATOM 314  N N   . SER A 1 42  ? 14.641  -7.168  -4.492  1.0 97.29 ? 42  SER A N   1 O43570 UNP 42  S 
ATOM 315  C CA  . SER A 1 42  ? 15.702  -6.505  -5.254  1.0 97.29 ? 42  SER A CA  1 O43570 UNP 42  S 
ATOM 316  C C   . SER A 1 42  ? 15.520  -4.988  -5.365  1.0 97.29 ? 42  SER A C   1 O43570 UNP 42  S 
ATOM 317  C CB  . SER A 1 42  ? 15.788  -7.106  -6.662  1.0 97.29 ? 42  SER A CB  1 O43570 UNP 42  S 
ATOM 318  O O   . SER A 1 42  ? 16.434  -4.323  -5.861  1.0 97.29 ? 42  SER A O   1 O43570 UNP 42  S 
ATOM 319  O OG  . SER A 1 42  ? 16.529  -8.316  -6.698  1.0 97.29 ? 42  SER A OG  1 O43570 UNP 42  S 
ATOM 320  N N   . TRP A 1 43  ? 14.394  -4.409  -4.929  1.0 97.94 ? 43  TRP A N   1 O43570 UNP 43  W 
ATOM 321  C CA  . TRP A 1 43  ? 14.104  -2.987  -5.161  1.0 97.94 ? 43  TRP A CA  1 O43570 UNP 43  W 
ATOM 322  C C   . TRP A 1 43  ? 15.146  -2.058  -4.534  1.0 97.94 ? 43  TRP A C   1 O43570 UNP 43  W 
ATOM 323  C CB  . TRP A 1 43  ? 12.708  -2.642  -4.641  1.0 97.94 ? 43  TRP A CB  1 O43570 UNP 43  W 
ATOM 324  O O   . TRP A 1 43  ? 15.585  -1.104  -5.182  1.0 97.94 ? 43  TRP A O   1 O43570 UNP 43  W 
ATOM 325  C CG  . TRP A 1 43  ? 11.539  -3.195  -5.396  1.0 97.94 ? 43  TRP A CG  1 O43570 UNP 43  W 
ATOM 326  C CD1 . TRP A 1 43  ? 11.557  -3.921  -6.541  1.0 97.94 ? 43  TRP A CD1 1 O43570 UNP 43  W 
ATOM 327  C CD2 . TRP A 1 43  ? 10.133  -3.102  -5.014  1.0 97.94 ? 43  TRP A CD2 1 O43570 UNP 43  W 
ATOM 328  C CE2 . TRP A 1 43  ? 9.347   -3.776  -5.995  1.0 97.94 ? 43  TRP A CE2 1 O43570 UNP 43  W 
ATOM 329  C CE3 . TRP A 1 43  ? 9.454   -2.557  -3.905  1.0 97.94 ? 43  TRP A CE3 1 O43570 UNP 43  W 
ATOM 330  N NE1 . TRP A 1 43  ? 10.266  -4.260  -6.896  1.0 97.94 ? 43  TRP A NE1 1 O43570 UNP 43  W 
ATOM 331  C CH2 . TRP A 1 43  ? 7.310   -3.350  -4.776  1.0 97.94 ? 43  TRP A CH2 1 O43570 UNP 43  W 
ATOM 332  C CZ2 . TRP A 1 43  ? 7.959   -3.913  -5.886  1.0 97.94 ? 43  TRP A CZ2 1 O43570 UNP 43  W 
ATOM 333  C CZ3 . TRP A 1 43  ? 8.058   -2.677  -3.795  1.0 97.94 ? 43  TRP A CZ3 1 O43570 UNP 43  W 
ATOM 334  N N   . SER A 1 44  ? 15.630  -2.379  -3.331  1.0 97.24 ? 44  SER A N   1 O43570 UNP 44  S 
ATOM 335  C CA  . SER A 1 44  ? 16.625  -1.576  -2.602  1.0 97.24 ? 44  SER A CA  1 O43570 UNP 44  S 
ATOM 336  C C   . SER A 1 44  ? 17.947  -1.376  -3.356  1.0 97.24 ? 44  SER A C   1 O43570 UNP 44  S 
ATOM 337  C CB  . SER A 1 44  ? 16.881  -2.188  -1.224  1.0 97.24 ? 44  SER A CB  1 O43570 UNP 44  S 
ATOM 338  O O   . SER A 1 44  ? 18.636  -0.386  -3.120  1.0 97.24 ? 44  SER A O   1 O43570 UNP 44  S 
ATOM 339  O OG  . SER A 1 44  ? 17.380  -3.502  -1.375  1.0 97.24 ? 44  SER A OG  1 O43570 UNP 44  S 
ATOM 340  N N   . LYS A 1 45  ? 18.277  -2.245  -4.327  1.0 96.32 ? 45  LYS A N   1 O43570 UNP 45  K 
ATOM 341  C CA  . LYS A 1 45  ? 19.484  -2.125  -5.168  1.0 96.32 ? 45  LYS A CA  1 O43570 UNP 45  K 
ATOM 342  C C   . LYS A 1 45  ? 19.490  -0.856  -6.021  1.0 96.32 ? 45  LYS A C   1 O43570 UNP 45  K 
ATOM 343  C CB  . LYS A 1 45  ? 19.604  -3.339  -6.103  1.0 96.32 ? 45  LYS A CB  1 O43570 UNP 45  K 
ATOM 344  O O   . LYS A 1 45  ? 20.551  -0.297  -6.279  1.0 96.32 ? 45  LYS A O   1 O43570 UNP 45  K 
ATOM 345  C CG  . LYS A 1 45  ? 19.808  -4.666  -5.358  1.0 96.32 ? 45  LYS A CG  1 O43570 UNP 45  K 
ATOM 346  C CD  . LYS A 1 45  ? 19.739  -5.841  -6.341  1.0 96.32 ? 45  LYS A CD  1 O43570 UNP 45  K 
ATOM 347  C CE  . LYS A 1 45  ? 19.928  -7.162  -5.588  1.0 96.32 ? 45  LYS A CE  1 O43570 UNP 45  K 
ATOM 348  N NZ  . LYS A 1 45  ? 19.450  -8.319  -6.384  1.0 96.32 ? 45  LYS A NZ  1 O43570 UNP 45  K 
ATOM 349  N N   . LYS A 1 46  ? 18.318  -0.435  -6.505  1.0 96.06 ? 46  LYS A N   1 O43570 UNP 46  K 
ATOM 350  C CA  . LYS A 1 46  ? 18.149  0.773   -7.335  1.0 96.06 ? 46  LYS A CA  1 O43570 UNP 46  K 
ATOM 351  C C   . LYS A 1 46  ? 17.397  1.886   -6.622  1.0 96.06 ? 46  LYS A C   1 O43570 UNP 46  K 
ATOM 352  C CB  . LYS A 1 46  ? 17.434  0.422   -8.640  1.0 96.06 ? 46  LYS A CB  1 O43570 UNP 46  K 
ATOM 353  O O   . LYS A 1 46  ? 17.538  3.046   -6.995  1.0 96.06 ? 46  LYS A O   1 O43570 UNP 46  K 
ATOM 354  C CG  . LYS A 1 46  ? 18.326  -0.401  -9.575  1.0 96.06 ? 46  LYS A CG  1 O43570 UNP 46  K 
ATOM 355  C CD  . LYS A 1 46  ? 17.698  -0.421  -10.969 1.0 96.06 ? 46  LYS A CD  1 O43570 UNP 46  K 
ATOM 356  C CE  . LYS A 1 46  ? 18.650  -1.076  -11.967 1.0 96.06 ? 46  LYS A CE  1 O43570 UNP 46  K 
ATOM 357  N NZ  . LYS A 1 46  ? 18.313  -0.643  -13.342 1.0 96.06 ? 46  LYS A NZ  1 O43570 UNP 46  K 
ATOM 358  N N   . TYR A 1 47  ? 16.620  1.530   -5.608  1.0 97.08 ? 47  TYR A N   1 O43570 UNP 47  Y 
ATOM 359  C CA  . TYR A 1 47  ? 15.760  2.429   -4.858  1.0 97.08 ? 47  TYR A CA  1 O43570 UNP 47  Y 
ATOM 360  C C   . TYR A 1 47  ? 16.068  2.268   -3.366  1.0 97.08 ? 47  TYR A C   1 O43570 UNP 47  Y 
ATOM 361  C CB  . TYR A 1 47  ? 14.306  2.101   -5.214  1.0 97.08 ? 47  TYR A CB  1 O43570 UNP 47  Y 
ATOM 362  O O   . TYR A 1 47  ? 15.342  1.561   -2.669  1.0 97.08 ? 47  TYR A O   1 O43570 UNP 47  Y 
ATOM 363  C CG  . TYR A 1 47  ? 14.022  2.121   -6.702  1.0 97.08 ? 47  TYR A CG  1 O43570 UNP 47  Y 
ATOM 364  C CD1 . TYR A 1 47  ? 13.840  3.346   -7.369  1.0 97.08 ? 47  TYR A CD1 1 O43570 UNP 47  Y 
ATOM 365  C CD2 . TYR A 1 47  ? 13.922  0.909   -7.416  1.0 97.08 ? 47  TYR A CD2 1 O43570 UNP 47  Y 
ATOM 366  C CE1 . TYR A 1 47  ? 13.524  3.363   -8.741  1.0 97.08 ? 47  TYR A CE1 1 O43570 UNP 47  Y 
ATOM 367  C CE2 . TYR A 1 47  ? 13.615  0.921   -8.789  1.0 97.08 ? 47  TYR A CE2 1 O43570 UNP 47  Y 
ATOM 368  O OH  . TYR A 1 47  ? 13.096  2.155   -10.774 1.0 97.08 ? 47  TYR A OH  1 O43570 UNP 47  Y 
ATOM 369  C CZ  . TYR A 1 47  ? 13.405  2.148   -9.450  1.0 97.08 ? 47  TYR A CZ  1 O43570 UNP 47  Y 
ATOM 370  N N   . PRO A 1 48  ? 17.158  2.879   -2.858  1.0 97.27 ? 48  PRO A N   1 O43570 UNP 48  P 
ATOM 371  C CA  . PRO A 1 48  ? 17.660  2.611   -1.508  1.0 97.27 ? 48  PRO A CA  1 O43570 UNP 48  P 
ATOM 372  C C   . PRO A 1 48  ? 16.624  2.792   -0.395  1.0 97.27 ? 48  PRO A C   1 O43570 UNP 48  P 
ATOM 373  C CB  . PRO A 1 48  ? 18.847  3.561   -1.324  1.0 97.27 ? 48  PRO A CB  1 O43570 UNP 48  P 
ATOM 374  O O   . PRO A 1 48  ? 16.644  2.044   0.579   1.0 97.27 ? 48  PRO A O   1 O43570 UNP 48  P 
ATOM 375  C CG  . PRO A 1 48  ? 19.378  3.723   -2.745  1.0 97.27 ? 48  PRO A CG  1 O43570 UNP 48  P 
ATOM 376  C CD  . PRO A 1 48  ? 18.102  3.725   -3.580  1.0 97.27 ? 48  PRO A CD  1 O43570 UNP 48  P 
ATOM 377  N N   . SER A 1 49  ? 15.674  3.722   -0.553  1.0 97.41 ? 49  SER A N   1 O43570 UNP 49  S 
ATOM 378  C CA  . SER A 1 49  ? 14.594  3.920   0.421   1.0 97.41 ? 49  SER A CA  1 O43570 UNP 49  S 
ATOM 379  C C   . SER A 1 49  ? 13.716  2.679   0.612   1.0 97.41 ? 49  SER A C   1 O43570 UNP 49  S 
ATOM 380  C CB  . SER A 1 49  ? 13.712  5.112   0.042   1.0 97.41 ? 49  SER A CB  1 O43570 UNP 49  S 
ATOM 381  O O   . SER A 1 49  ? 13.162  2.535   1.691   1.0 97.41 ? 49  SER A O   1 O43570 UNP 49  S 
ATOM 382  O OG  . SER A 1 49  ? 14.481  6.294   -0.107  1.0 97.41 ? 49  SER A OG  1 O43570 UNP 49  S 
ATOM 383  N N   . CYS A 1 50  ? 13.651  1.744   -0.346  1.0 97.91 ? 50  CYS A N   1 O43570 UNP 50  C 
ATOM 384  C CA  . CYS A 1 50  ? 12.898  0.493   -0.194  1.0 97.91 ? 50  CYS A CA  1 O43570 UNP 50  C 
ATOM 385  C C   . CYS A 1 50  ? 13.465  -0.442  0.886   1.0 97.91 ? 50  CYS A C   1 O43570 UNP 50  C 
ATOM 386  C CB  . CYS A 1 50  ? 12.806  -0.236  -1.543  1.0 97.91 ? 50  CYS A CB  1 O43570 UNP 50  C 
ATOM 387  O O   . CYS A 1 50  ? 12.745  -1.310  1.365   1.0 97.91 ? 50  CYS A O   1 O43570 UNP 50  C 
ATOM 388  S SG  . CYS A 1 50  ? 12.000  0.685   -2.883  1.0 97.91 ? 50  CYS A SG  1 O43570 UNP 50  C 
ATOM 389  N N   . GLY A 1 51  ? 14.735  -0.272  1.271   1.0 96.86 ? 51  GLY A N   1 O43570 UNP 51  G 
ATOM 390  C CA  . GLY A 1 51  ? 15.339  -0.925  2.441   1.0 96.86 ? 51  GLY A CA  1 O43570 UNP 51  G 
ATOM 391  C C   . GLY A 1 51  ? 15.511  0.020   3.635   1.0 96.86 ? 51  GLY A C   1 O43570 UNP 51  G 
ATOM 392  O O   . GLY A 1 51  ? 16.302  -0.269  4.528   1.0 96.86 ? 51  GLY A O   1 O43570 UNP 51  G 
ATOM 393  N N   . GLY A 1 52  ? 14.860  1.185   3.597   1.0 95.59 ? 52  GLY A N   1 O43570 UNP 52  G 
ATOM 394  C CA  . GLY A 1 52  ? 14.978  2.237   4.599   1.0 95.59 ? 52  GLY A CA  1 O43570 UNP 52  G 
ATOM 395  C C   . GLY A 1 52  ? 13.971  2.110   5.740   1.0 95.59 ? 52  GLY A C   1 O43570 UNP 52  G 
ATOM 396  O O   . GLY A 1 52  ? 13.380  1.062   5.982   1.0 95.59 ? 52  GLY A O   1 O43570 UNP 52  G 
ATOM 397  N N   . LEU A 1 53  ? 13.777  3.221   6.451   1.0 95.71 ? 53  LEU A N   1 O43570 UNP 53  L 
ATOM 398  C CA  . LEU A 1 53  ? 12.833  3.327   7.562   1.0 95.71 ? 53  LEU A CA  1 O43570 UNP 53  L 
ATOM 399  C C   . LEU A 1 53  ? 11.401  3.579   7.068   1.0 95.71 ? 53  LEU A C   1 O43570 UNP 53  L 
ATOM 400  C CB  . LEU A 1 53  ? 13.300  4.442   8.520   1.0 95.71 ? 53  LEU A CB  1 O43570 UNP 53  L 
ATOM 401  O O   . LEU A 1 53  ? 11.185  3.959   5.916   1.0 95.71 ? 53  LEU A O   1 O43570 UNP 53  L 
ATOM 402  C CG  . LEU A 1 53  ? 14.720  4.255   9.089   1.0 95.71 ? 53  LEU A CG  1 O43570 UNP 53  L 
ATOM 403  C CD1 . LEU A 1 53  ? 15.079  5.456   9.963   1.0 95.71 ? 53  LEU A CD1 1 O43570 UNP 53  L 
ATOM 404  C CD2 . LEU A 1 53  ? 14.846  2.984   9.929   1.0 95.71 ? 53  LEU A CD2 1 O43570 UNP 53  L 
ATOM 405  N N   . LEU A 1 54  ? 10.437  3.418   7.982   1.0 97.32 ? 54  LEU A N   1 O43570 UNP 54  L 
ATOM 406  C CA  . LEU A 1 54  ? 9.019   3.750   7.786   1.0 97.32 ? 54  LEU A CA  1 O43570 UNP 54  L 
ATOM 407  C C   . LEU A 1 54  ? 8.402   3.104   6.535   1.0 97.32 ? 54  LEU A C   1 O43570 UNP 54  L 
ATOM 408  C CB  . LEU A 1 54  ? 8.808   5.280   7.820   1.0 97.32 ? 54  LEU A CB  1 O43570 UNP 54  L 
ATOM 409  O O   . LEU A 1 54  ? 7.613   3.740   5.844   1.0 97.32 ? 54  LEU A O   1 O43570 UNP 54  L 
ATOM 410  C CG  . LEU A 1 54  ? 9.320   6.020   9.064   1.0 97.32 ? 54  LEU A CG  1 O43570 UNP 54  L 
ATOM 411  C CD1 . LEU A 1 54  ? 9.088   7.521   8.897   1.0 97.32 ? 54  LEU A CD1 1 O43570 UNP 54  L 
ATOM 412  C CD2 . LEU A 1 54  ? 8.595   5.568   10.330  1.0 97.32 ? 54  LEU A CD2 1 O43570 UNP 54  L 
ATOM 413  N N   . GLN A 1 55  ? 8.777   1.862   6.227   1.0 98.53 ? 55  GLN A N   1 O43570 UNP 55  Q 
ATOM 414  C CA  . GLN A 1 55  ? 8.244   1.164   5.062   1.0 98.53 ? 55  GLN A CA  1 O43570 UNP 55  Q 
ATOM 415  C C   . GLN A 1 55  ? 6.781   0.743   5.255   1.0 98.53 ? 55  GLN A C   1 O43570 UNP 55  Q 
ATOM 416  C CB  . GLN A 1 55  ? 9.146   -0.015  4.665   1.0 98.53 ? 55  GLN A CB  1 O43570 UNP 55  Q 
ATOM 417  O O   . GLN A 1 55  ? 6.333   0.484   6.372   1.0 98.53 ? 55  GLN A O   1 O43570 UNP 55  Q 
ATOM 418  C CG  . GLN A 1 55  ? 10.528  0.421   4.163   1.0 98.53 ? 55  GLN A CG  1 O43570 UNP 55  Q 
ATOM 419  C CD  . GLN A 1 55  ? 10.421  1.238   2.883   1.0 98.53 ? 55  GLN A CD  1 O43570 UNP 55  Q 
ATOM 420  N NE2 . GLN A 1 55  ? 10.526  2.548   2.967   1.0 98.53 ? 55  GLN A NE2 1 O43570 UNP 55  Q 
ATOM 421  O OE1 . GLN A 1 55  ? 10.194  0.705   1.803   1.0 98.53 ? 55  GLN A OE1 1 O43570 UNP 55  Q 
ATOM 422  N N   . SER A 1 56  ? 6.077   0.682   4.129   1.0 98.83 ? 56  SER A N   1 O43570 UNP 56  S 
ATOM 423  C CA  . SER A 1 56  ? 4.700   0.211   3.961   1.0 98.83 ? 56  SER A CA  1 O43570 UNP 56  S 
ATOM 424  C C   . SER A 1 56  ? 4.648   -0.874  2.871   1.0 98.83 ? 56  SER A C   1 O43570 UNP 56  S 
ATOM 425  C CB  . SER A 1 56  ? 3.815   1.394   3.553   1.0 98.83 ? 56  SER A CB  1 O43570 UNP 56  S 
ATOM 426  O O   . SER A 1 56  ? 5.534   -0.879  1.998   1.0 98.83 ? 56  SER A O   1 O43570 UNP 56  S 
ATOM 427  O OG  . SER A 1 56  ? 3.744   2.346   4.598   1.0 98.83 ? 56  SER A OG  1 O43570 UNP 56  S 
ATOM 428  N N   . PRO A 1 57  ? 3.626   -1.753  2.860   1.0 98.84 ? 57  PRO A N   1 O43570 UNP 57  P 
ATOM 429  C CA  . PRO A 1 57  ? 2.492   -1.843  3.797   1.0 98.84 ? 57  PRO A CA  1 O43570 UNP 57  P 
ATOM 430  C C   . PRO A 1 57  ? 2.865   -2.537  5.117   1.0 98.84 ? 57  PRO A C   1 O43570 UNP 57  P 
ATOM 431  C CB  . PRO A 1 57  ? 1.442   -2.646  3.030   1.0 98.84 ? 57  PRO A CB  1 O43570 UNP 57  P 
ATOM 432  O O   . PRO A 1 57  ? 4.003   -2.964  5.290   1.0 98.84 ? 57  PRO A O   1 O43570 UNP 57  P 
ATOM 433  C CG  . PRO A 1 57  ? 2.307   -3.644  2.261   1.0 98.84 ? 57  PRO A CG  1 O43570 UNP 57  P 
ATOM 434  C CD  . PRO A 1 57  ? 3.499   -2.792  1.846   1.0 98.84 ? 57  PRO A CD  1 O43570 UNP 57  P 
ATOM 435  N N   . ILE A 1 58  ? 1.925   -2.633  6.060   1.0 98.87 ? 58  ILE A N   1 O43570 UNP 58  I 
ATOM 436  C CA  . ILE A 1 58  ? 2.113   -3.268  7.379   1.0 98.87 ? 58  ILE A CA  1 O43570 UNP 58  I 
ATOM 437  C C   . ILE A 1 58  ? 0.904   -4.138  7.740   1.0 98.87 ? 58  ILE A C   1 O43570 UNP 58  I 
ATOM 438  C CB  . ILE A 1 58  ? 2.388   -2.215  8.482   1.0 98.87 ? 58  ILE A CB  1 O43570 UNP 58  I 
ATOM 439  O O   . ILE A 1 58  ? -0.174  -3.966  7.165   1.0 98.87 ? 58  ILE A O   1 O43570 UNP 58  I 
ATOM 440  C CG1 . ILE A 1 58  ? 1.174   -1.290  8.732   1.0 98.87 ? 58  ILE A CG1 1 O43570 UNP 58  I 
ATOM 441  C CG2 . ILE A 1 58  ? 3.649   -1.409  8.124   1.0 98.87 ? 58  ILE A CG2 1 O43570 UNP 58  I 
ATOM 442  C CD1 . ILE A 1 58  ? 1.334   -0.342  9.925   1.0 98.87 ? 58  ILE A CD1 1 O43570 UNP 58  I 
ATOM 443  N N   . ASP A 1 59  ? 1.075   -5.030  8.713   1.0 98.79 ? 59  ASP A N   1 O43570 UNP 59  D 
ATOM 444  C CA  . ASP A 1 59  ? -0.049  -5.699  9.373   1.0 98.79 ? 59  ASP A CA  1 O43570 UNP 59  D 
ATOM 445  C C   . ASP A 1 59  ? -0.658  -4.799  10.456  1.0 98.79 ? 59  ASP A C   1 O43570 UNP 59  D 
ATOM 446  C CB  . ASP A 1 59  ? 0.389   -7.059  9.938   1.0 98.79 ? 59  ASP A CB  1 O43570 UNP 59  D 
ATOM 447  O O   . ASP A 1 59  ? 0.050   -4.224  11.282  1.0 98.79 ? 59  ASP A O   1 O43570 UNP 59  D 
ATOM 448  C CG  . ASP A 1 59  ? -0.753  -7.816  10.636  1.0 98.79 ? 59  ASP A CG  1 O43570 UNP 59  D 
ATOM 449  O OD1 . ASP A 1 59  ? -1.943  -7.615  10.297  1.0 98.79 ? 59  ASP A OD1 1 O43570 UNP 59  D 
ATOM 450  O OD2 . ASP A 1 59  ? -0.453  -8.607  11.553  1.0 98.79 ? 59  ASP A OD2 1 O43570 UNP 59  D 
ATOM 451  N N   . LEU A 1 60  ? -1.981  -4.668  10.439  1.0 98.59 ? 60  LEU A N   1 O43570 UNP 60  L 
ATOM 452  C CA  . LEU A 1 60  ? -2.779  -3.903  11.389  1.0 98.59 ? 60  LEU A CA  1 O43570 UNP 60  L 
ATOM 453  C C   . LEU A 1 60  ? -3.369  -4.869  12.426  1.0 98.59 ? 60  LEU A C   1 O43570 UNP 60  L 
ATOM 454  C CB  . LEU A 1 60  ? -3.860  -3.109  10.626  1.0 98.59 ? 60  LEU A CB  1 O43570 UNP 60  L 
ATOM 455  O O   . LEU A 1 60  ? -4.495  -5.353  12.286  1.0 98.59 ? 60  LEU A O   1 O43570 UNP 60  L 
ATOM 456  C CG  . LEU A 1 60  ? -3.345  -2.210  9.485   1.0 98.59 ? 60  LEU A CG  1 O43570 UNP 60  L 
ATOM 457  C CD1 . LEU A 1 60  ? -4.531  -1.595  8.745   1.0 98.59 ? 60  LEU A CD1 1 O43570 UNP 60  L 
ATOM 458  C CD2 . LEU A 1 60  ? -2.476  -1.062  9.998   1.0 98.59 ? 60  LEU A CD2 1 O43570 UNP 60  L 
ATOM 459  N N   . HIS A 1 61  ? -2.610  -5.154  13.483  1.0 97.52 ? 61  HIS A N   1 O43570 UNP 61  H 
ATOM 460  C CA  . HIS A 1 61  ? -2.984  -6.110  14.531  1.0 97.52 ? 61  HIS A CA  1 O43570 UNP 61  H 
ATOM 461  C C   . HIS A 1 61  ? -3.115  -5.447  15.907  1.0 97.52 ? 61  HIS A C   1 O43570 UNP 61  H 
ATOM 462  C CB  . HIS A 1 61  ? -1.971  -7.257  14.552  1.0 97.52 ? 61  HIS A CB  1 O43570 UNP 61  H 
ATOM 463  O O   . HIS A 1 61  ? -2.473  -4.437  16.178  1.0 97.52 ? 61  HIS A O   1 O43570 UNP 61  H 
ATOM 464  C CG  . HIS A 1 61  ? -0.585  -6.833  14.967  1.0 97.52 ? 61  HIS A CG  1 O43570 UNP 61  H 
ATOM 465  C CD2 . HIS A 1 61  ? 0.517   -6.741  14.159  1.0 97.52 ? 61  HIS A CD2 1 O43570 UNP 61  H 
ATOM 466  N ND1 . HIS A 1 61  ? -0.175  -6.512  16.241  1.0 97.52 ? 61  HIS A ND1 1 O43570 UNP 61  H 
ATOM 467  C CE1 . HIS A 1 61  ? 1.139   -6.253  16.202  1.0 97.52 ? 61  HIS A CE1 1 O43570 UNP 61  H 
ATOM 468  N NE2 . HIS A 1 61  ? 1.605   -6.365  14.954  1.0 97.52 ? 61  HIS A NE2 1 O43570 UNP 61  H 
ATOM 469  N N   . SER A 1 62  ? -3.916  -6.038  16.801  1.0 95.25 ? 62  SER A N   1 O43570 UNP 62  S 
ATOM 470  C CA  . SER A 1 62  ? -4.310  -5.460  18.101  1.0 95.25 ? 62  SER A CA  1 O43570 UNP 62  S 
ATOM 471  C C   . SER A 1 62  ? -3.167  -4.865  18.924  1.0 95.25 ? 62  SER A C   1 O43570 UNP 62  S 
ATOM 472  C CB  . SER A 1 62  ? -5.013  -6.522  18.956  1.0 95.25 ? 62  SER A CB  1 O43570 UNP 62  S 
ATOM 473  O O   . SER A 1 62  ? -3.333  -3.791  19.492  1.0 95.25 ? 62  SER A O   1 O43570 UNP 62  S 
ATOM 474  O OG  . SER A 1 62  ? -4.261  -7.725  19.028  1.0 95.25 ? 62  SER A OG  1 O43570 UNP 62  S 
ATOM 475  N N   . ASP A 1 63  ? -2.017  -5.535  18.965  1.0 95.79 ? 63  ASP A N   1 O43570 UNP 63  D 
ATOM 476  C CA  . ASP A 1 63  ? -0.925  -5.201  19.891  1.0 95.79 ? 63  ASP A CA  1 O43570 UNP 63  D 
ATOM 477  C C   . ASP A 1 63  ? -0.238  -3.857  19.597  1.0 95.79 ? 63  ASP A C   1 O43570 UNP 63  D 
ATOM 478  C CB  . ASP A 1 63  ? 0.107   -6.341  19.903  1.0 95.79 ? 63  ASP A CB  1 O43570 UNP 63  D 
ATOM 479  O O   . ASP A 1 63  ? 0.421   -3.305  20.475  1.0 95.79 ? 63  ASP A O   1 O43570 UNP 63  D 
ATOM 480  C CG  . ASP A 1 63  ? -0.482  -7.716  20.238  1.0 95.79 ? 63  ASP A CG  1 O43570 UNP 63  D 
ATOM 481  O OD1 . ASP A 1 63  ? -1.658  -7.778  20.676  1.0 95.79 ? 63  ASP A OD1 1 O43570 UNP 63  D 
ATOM 482  O OD2 . ASP A 1 63  ? 0.233   -8.709  19.994  1.0 95.79 ? 63  ASP A OD2 1 O43570 UNP 63  D 
ATOM 483  N N   . ILE A 1 64  ? -0.405  -3.315  18.386  1.0 97.25 ? 64  ILE A N   1 O43570 UNP 64  I 
ATOM 484  C CA  . ILE A 1 64  ? 0.156   -2.015  17.982  1.0 97.25 ? 64  ILE A CA  1 O43570 UNP 64  I 
ATOM 485  C C   . ILE A 1 64  ? -0.910  -0.925  17.824  1.0 97.25 ? 64  ILE A C   1 O43570 UNP 64  I 
ATOM 486  C CB  . ILE A 1 64  ? 1.010   -2.149  16.702  1.0 97.25 ? 64  ILE A CB  1 O43570 UNP 64  I 
ATOM 487  O O   . ILE A 1 64  ? -0.570  0.211   17.485  1.0 97.25 ? 64  ILE A O   1 O43570 UNP 64  I 
ATOM 488  C CG1 . ILE A 1 64  ? 0.172   -2.687  15.521  1.0 97.25 ? 64  ILE A CG1 1 O43570 UNP 64  I 
ATOM 489  C CG2 . ILE A 1 64  ? 2.260   -2.995  16.993  1.0 97.25 ? 64  ILE A CG2 1 O43570 UNP 64  I 
ATOM 490  C CD1 . ILE A 1 64  ? 0.873   -2.578  14.167  1.0 97.25 ? 64  ILE A CD1 1 O43570 UNP 64  I 
ATOM 491  N N   . LEU A 1 65  ? -2.193  -1.247  18.027  1.0 98.02 ? 65  LEU A N   1 O43570 UNP 65  L 
ATOM 492  C CA  . LEU A 1 65  ? -3.284  -0.290  17.850  1.0 98.02 ? 65  LEU A CA  1 O43570 UNP 65  L 
ATOM 493  C C   . LEU A 1 65  ? -3.474  0.551   19.110  1.0 98.02 ? 65  LEU A C   1 O43570 UNP 65  L 
ATOM 494  C CB  . LEU A 1 65  ? -4.601  -0.983  17.460  1.0 98.02 ? 65  LEU A CB  1 O43570 UNP 65  L 
ATOM 495  O O   . LEU A 1 65  ? -3.707  0.026   20.196  1.0 98.02 ? 65  LEU A O   1 O43570 UNP 65  L 
ATOM 496  C CG  . LEU A 1 65  ? -4.529  -1.809  16.171  1.0 98.02 ? 65  LEU A CG  1 O43570 UNP 65  L 
ATOM 497  C CD1 . LEU A 1 65  ? -5.882  -2.429  15.859  1.0 98.02 ? 65  LEU A CD1 1 O43570 UNP 65  L 
ATOM 498  C CD2 . LEU A 1 65  ? -4.024  -1.038  14.959  1.0 98.02 ? 65  LEU A CD2 1 O43570 UNP 65  L 
ATOM 499  N N   . GLN A 1 66  ? -3.461  1.872   18.948  1.0 97.97 ? 66  GLN A N   1 O43570 UNP 66  Q 
ATOM 500  C CA  . GLN A 1 66  ? -3.755  2.811   20.025  1.0 97.97 ? 66  GLN A CA  1 O43570 UNP 66  Q 
ATOM 501  C C   . GLN A 1 66  ? -4.875  3.763   19.610  1.0 97.97 ? 66  GLN A C   1 O43570 UNP 66  Q 
ATOM 502  C CB  . GLN A 1 66  ? -2.469  3.543   20.434  1.0 97.97 ? 66  GLN A CB  1 O43570 UNP 66  Q 
ATOM 503  O O   . GLN A 1 66  ? -4.792  4.416   18.572  1.0 97.97 ? 66  GLN A O   1 O43570 UNP 66  Q 
ATOM 504  C CG  . GLN A 1 66  ? -2.700  4.360   21.712  1.0 97.97 ? 66  GLN A CG  1 O43570 UNP 66  Q 
ATOM 505  C CD  . GLN A 1 66  ? -1.426  5.015   22.225  1.0 97.97 ? 66  GLN A CD  1 O43570 UNP 66  Q 
ATOM 506  N NE2 . GLN A 1 66  ? -1.347  6.327   22.230  1.0 97.97 ? 66  GLN A NE2 1 O43570 UNP 66  Q 
ATOM 507  O OE1 . GLN A 1 66  ? -0.488  4.373   22.658  1.0 97.97 ? 66  GLN A OE1 1 O43570 UNP 66  Q 
ATOM 508  N N   . TYR A 1 67  ? -5.932  3.861   20.415  1.0 98.18 ? 67  TYR A N   1 O43570 UNP 67  Y 
ATOM 509  C CA  . TYR A 1 67  ? -6.986  4.846   20.176  1.0 98.18 ? 67  TYR A CA  1 O43570 UNP 67  Y 
ATOM 510  C C   . TYR A 1 67  ? -6.451  6.270   20.367  1.0 98.18 ? 67  TYR A C   1 O43570 UNP 67  Y 
ATOM 511  C CB  . TYR A 1 67  ? -8.194  4.568   21.074  1.0 98.18 ? 67  TYR A CB  1 O43570 UNP 67  Y 
ATOM 512  O O   . TYR A 1 67  ? -5.790  6.562   21.366  1.0 98.18 ? 67  TYR A O   1 O43570 UNP 67  Y 
ATOM 513  C CG  . TYR A 1 67  ? -9.277  5.625   20.966  1.0 98.18 ? 67  TYR A CG  1 O43570 UNP 67  Y 
ATOM 514  C CD1 . TYR A 1 67  ? -9.593  6.432   22.077  1.0 98.18 ? 67  TYR A CD1 1 O43570 UNP 67  Y 
ATOM 515  C CD2 . TYR A 1 67  ? -9.931  5.839   19.738  1.0 98.18 ? 67  TYR A CD2 1 O43570 UNP 67  Y 
ATOM 516  C CE1 . TYR A 1 67  ? -10.572 7.439   21.966  1.0 98.18 ? 67  TYR A CE1 1 O43570 UNP 67  Y 
ATOM 517  C CE2 . TYR A 1 67  ? -10.907 6.845   19.624  1.0 98.18 ? 67  TYR A CE2 1 O43570 UNP 67  Y 
ATOM 518  O OH  . TYR A 1 67  ? -12.176 8.614   20.619  1.0 98.18 ? 67  TYR A OH  1 O43570 UNP 67  Y 
ATOM 519  C CZ  . TYR A 1 67  ? -11.231 7.646   20.734  1.0 98.18 ? 67  TYR A CZ  1 O43570 UNP 67  Y 
ATOM 520  N N   . ASP A 1 68  ? -6.764  7.152   19.421  1.0 97.99 ? 68  ASP A N   1 O43570 UNP 68  D 
ATOM 521  C CA  . ASP A 1 68  ? -6.410  8.566   19.459  1.0 97.99 ? 68  ASP A CA  1 O43570 UNP 68  D 
ATOM 522  C C   . ASP A 1 68  ? -7.642  9.421   19.144  1.0 97.99 ? 68  ASP A C   1 O43570 UNP 68  D 
ATOM 523  C CB  . ASP A 1 68  ? -5.243  8.829   18.501  1.0 97.99 ? 68  ASP A CB  1 O43570 UNP 68  D 
ATOM 524  O O   . ASP A 1 68  ? -8.082  9.528   18.001  1.0 97.99 ? 68  ASP A O   1 O43570 UNP 68  D 
ATOM 525  C CG  . ASP A 1 68  ? -4.743  10.277  18.544  1.0 97.99 ? 68  ASP A CG  1 O43570 UNP 68  D 
ATOM 526  O OD1 . ASP A 1 68  ? -5.388  11.135  19.197  1.0 97.99 ? 68  ASP A OD1 1 O43570 UNP 68  D 
ATOM 527  O OD2 . ASP A 1 68  ? -3.701  10.545  17.917  1.0 97.99 ? 68  ASP A OD2 1 O43570 UNP 68  D 
ATOM 528  N N   . ALA A 1 69  ? -8.186  10.061  20.181  1.0 97.17 ? 69  ALA A N   1 O43570 UNP 69  A 
ATOM 529  C CA  . ALA A 1 69  ? -9.367  10.913  20.076  1.0 97.17 ? 69  ALA A CA  1 O43570 UNP 69  A 
ATOM 530  C C   . ALA A 1 69  ? -9.138  12.194  19.249  1.0 97.17 ? 69  ALA A C   1 O43570 UNP 69  A 
ATOM 531  C CB  . ALA A 1 69  ? -9.835  11.249  21.498  1.0 97.17 ? 69  ALA A CB  1 O43570 UNP 69  A 
ATOM 532  O O   . ALA A 1 69  ? -10.105 12.881  18.924  1.0 97.17 ? 69  ALA A O   1 O43570 UNP 69  A 
ATOM 533  N N   . SER A 1 70  ? -7.887  12.541  18.917  1.0 97.51 ? 70  SER A N   1 O43570 UNP 70  S 
ATOM 534  C CA  . SER A 1 70  ? -7.586  13.658  18.013  1.0 97.51 ? 70  SER A CA  1 O43570 UNP 70  S 
ATOM 535  C C   . SER A 1 70  ? -7.875  13.328  16.543  1.0 97.51 ? 70  SER A C   1 O43570 UNP 70  S 
ATOM 536  C CB  . SER A 1 70  ? -6.137  14.122  18.191  1.0 97.51 ? 70  SER A CB  1 O43570 UNP 70  S 
ATOM 537  O O   . SER A 1 70  ? -8.005  14.237  15.719  1.0 97.51 ? 70  SER A O   1 O43570 UNP 70  S 
ATOM 538  O OG  . SER A 1 70  ? -5.213  13.242  17.591  1.0 97.51 ? 70  SER A OG  1 O43570 UNP 70  S 
ATOM 539  N N   . LEU A 1 71  ? -8.025  12.040  16.208  1.0 98.20 ? 71  LEU A N   1 O43570 UNP 71  L 
ATOM 540  C CA  . LEU A 1 71  ? -8.369  11.570  14.870  1.0 98.20 ? 71  LEU A CA  1 O43570 UNP 71  L 
ATOM 541  C C   . LEU A 1 71  ? -9.861  11.765  14.592  1.0 98.20 ? 71  LEU A C   1 O43570 UNP 71  L 
ATOM 542  C CB  . LEU A 1 71  ? -7.929  10.110  14.704  1.0 98.20 ? 71  LEU A CB  1 O43570 UNP 71  L 
ATOM 543  O O   . LEU A 1 71  ? -10.691 10.885  14.803  1.0 98.20 ? 71  LEU A O   1 O43570 UNP 71  L 
ATOM 544  C CG  . LEU A 1 71  ? -6.416  9.877   14.809  1.0 98.20 ? 71  LEU A CG  1 O43570 UNP 71  L 
ATOM 545  C CD1 . LEU A 1 71  ? -6.137  8.398   14.549  1.0 98.20 ? 71  LEU A CD1 1 O43570 UNP 71  L 
ATOM 546  C CD2 . LEU A 1 71  ? -5.612  10.696  13.796  1.0 98.20 ? 71  LEU A CD2 1 O43570 UNP 71  L 
ATOM 547  N N   . THR A 1 72  ? -10.188 12.953  14.098  1.0 97.36 ? 72  THR A N   1 O43570 UNP 72  T 
ATOM 548  C CA  . THR A 1 72  ? -11.544 13.342  13.698  1.0 97.36 ? 72  THR A CA  1 O43570 UNP 72  T 
ATOM 549  C C   . THR A 1 72  ? -11.893 12.837  12.290  1.0 97.36 ? 72  THR A C   1 O43570 UNP 72  T 
ATOM 550  C CB  . THR A 1 72  ? -11.729 14.862  13.819  1.0 97.36 ? 72  THR A CB  1 O43570 UNP 72  T 
ATOM 551  O O   . THR A 1 72  ? -10.997 12.431  11.539  1.0 97.36 ? 72  THR A O   1 O43570 UNP 72  T 
ATOM 552  C CG2 . THR A 1 72  ? -11.647 15.323  15.275  1.0 97.36 ? 72  THR A CG2 1 O43570 UNP 72  T 
ATOM 553  O OG1 . THR A 1 72  ? -10.736 15.563  13.114  1.0 97.36 ? 72  THR A OG1 1 O43570 UNP 72  T 
ATOM 554  N N   . PRO A 1 73  ? -13.185 12.803  11.911  1.0 98.26 ? 73  PRO A N   1 O43570 UNP 73  P 
ATOM 555  C CA  . PRO A 1 73  ? -13.591 12.421  10.562  1.0 98.26 ? 73  PRO A CA  1 O43570 UNP 73  P 
ATOM 556  C C   . PRO A 1 73  ? -12.902 13.276  9.493   1.0 98.26 ? 73  PRO A C   1 O43570 UNP 73  P 
ATOM 557  C CB  . PRO A 1 73  ? -15.113 12.583  10.519  1.0 98.26 ? 73  PRO A CB  1 O43570 UNP 73  P 
ATOM 558  O O   . PRO A 1 73  ? -12.791 14.492  9.640   1.0 98.26 ? 73  PRO A O   1 O43570 UNP 73  P 
ATOM 559  C CG  . PRO A 1 73  ? -15.519 12.411  11.982  1.0 98.26 ? 73  PRO A CG  1 O43570 UNP 73  P 
ATOM 560  C CD  . PRO A 1 73  ? -14.360 13.061  12.732  1.0 98.26 ? 73  PRO A CD  1 O43570 UNP 73  P 
ATOM 561  N N   . LEU A 1 74  ? -12.451 12.630  8.419   1.0 98.37 ? 74  LEU A N   1 O43570 UNP 74  L 
ATOM 562  C CA  . LEU A 1 74  ? -11.959 13.332  7.238   1.0 98.37 ? 74  LEU A CA  1 O43570 UNP 74  L 
ATOM 563  C C   . LEU A 1 74  ? -13.138 13.843  6.410   1.0 98.37 ? 74  LEU A C   1 O43570 UNP 74  L 
ATOM 564  C CB  . LEU A 1 74  ? -11.057 12.413  6.399   1.0 98.37 ? 74  LEU A CB  1 O43570 UNP 74  L 
ATOM 565  O O   . LEU A 1 74  ? -14.181 13.196  6.331   1.0 98.37 ? 74  LEU A O   1 O43570 UNP 74  L 
ATOM 566  C CG  . LEU A 1 74  ? -9.790  11.914  7.113   1.0 98.37 ? 74  LEU A CG  1 O43570 UNP 74  L 
ATOM 567  C CD1 . LEU A 1 74  ? -8.974  11.062  6.140   1.0 98.37 ? 74  LEU A CD1 1 O43570 UNP 74  L 
ATOM 568  C CD2 . LEU A 1 74  ? -8.903  13.060  7.609   1.0 98.37 ? 74  LEU A CD2 1 O43570 UNP 74  L 
ATOM 569  N N   . GLU A 1 75  ? -12.939 14.978  5.756   1.0 98.40 ? 75  GLU A N   1 O43570 UNP 75  E 
ATOM 570  C CA  . GLU A 1 75  ? -13.892 15.551  4.813   1.0 98.40 ? 75  GLU A CA  1 O43570 UNP 75  E 
ATOM 571  C C   . GLU A 1 75  ? -13.347 15.410  3.385   1.0 98.40 ? 75  GLU A C   1 O43570 UNP 75  E 
ATOM 572  C CB  . GLU A 1 75  ? -14.138 17.019  5.169   1.0 98.40 ? 75  GLU A CB  1 O43570 UNP 75  E 
ATOM 573  O O   . GLU A 1 75  ? -12.216 15.811  3.091   1.0 98.40 ? 75  GLU A O   1 O43570 UNP 75  E 
ATOM 574  C CG  . GLU A 1 75  ? -14.937 17.266  6.451   1.0 98.40 ? 75  GLU A CG  1 O43570 UNP 75  E 
ATOM 575  C CD  . GLU A 1 75  ? -15.038 18.781  6.686   1.0 98.40 ? 75  GLU A CD  1 O43570 UNP 75  E 
ATOM 576  O OE1 . GLU A 1 75  ? -14.291 19.307  7.543   1.0 98.40 ? 75  GLU A OE1 1 O43570 UNP 75  E 
ATOM 577  O OE2 . GLU A 1 75  ? -15.808 19.433  5.942   1.0 98.40 ? 75  GLU A OE2 1 O43570 UNP 75  E 
ATOM 578  N N   . PHE A 1 76  ? -14.159 14.851  2.487   1.0 98.62 ? 76  PHE A N   1 O43570 UNP 76  F 
ATOM 579  C CA  . PHE A 1 76  ? -13.779 14.542  1.107   1.0 98.62 ? 76  PHE A CA  1 O43570 UNP 76  F 
ATOM 580  C C   . PHE A 1 76  ? -14.322 15.609  0.148   1.0 98.62 ? 76  PHE A C   1 O43570 UNP 76  F 
ATOM 581  C CB  . PHE A 1 76  ? -14.264 13.124  0.770   1.0 98.62 ? 76  PHE A CB  1 O43570 UNP 76  F 
ATOM 582  O O   . PHE A 1 76  ? -15.435 15.518  -0.368  1.0 98.62 ? 76  PHE A O   1 O43570 UNP 76  F 
ATOM 583  C CG  . PHE A 1 76  ? -13.862 12.069  1.780   1.0 98.62 ? 76  PHE A CG  1 O43570 UNP 76  F 
ATOM 584  C CD1 . PHE A 1 76  ? -12.506 11.747  1.985   1.0 98.62 ? 76  PHE A CD1 1 O43570 UNP 76  F 
ATOM 585  C CD2 . PHE A 1 76  ? -14.852 11.442  2.554   1.0 98.62 ? 76  PHE A CD2 1 O43570 UNP 76  F 
ATOM 586  C CE1 . PHE A 1 76  ? -12.145 10.813  2.974   1.0 98.62 ? 76  PHE A CE1 1 O43570 UNP 76  F 
ATOM 587  C CE2 . PHE A 1 76  ? -14.491 10.509  3.537   1.0 98.62 ? 76  PHE A CE2 1 O43570 UNP 76  F 
ATOM 588  C CZ  . PHE A 1 76  ? -13.139 10.195  3.752   1.0 98.62 ? 76  PHE A CZ  1 O43570 UNP 76  F 
ATOM 589  N N   . GLN A 1 77  ? -13.552 16.673  -0.086  1.0 98.59 ? 77  GLN A N   1 O43570 UNP 77  Q 
ATOM 590  C CA  . GLN A 1 77  ? -14.010 17.810  -0.887  1.0 98.59 ? 77  GLN A CA  1 O43570 UNP 77  Q 
ATOM 591  C C   . GLN A 1 77  ? -13.693 17.622  -2.371  1.0 98.59 ? 77  GLN A C   1 O43570 UNP 77  Q 
ATOM 592  C CB  . GLN A 1 77  ? -13.442 19.127  -0.350  1.0 98.59 ? 77  GLN A CB  1 O43570 UNP 77  Q 
ATOM 593  O O   . GLN A 1 77  ? -12.589 17.237  -2.745  1.0 98.59 ? 77  GLN A O   1 O43570 UNP 77  Q 
ATOM 594  C CG  . GLN A 1 77  ? -13.960 19.433  1.065   1.0 98.59 ? 77  GLN A CG  1 O43570 UNP 77  Q 
ATOM 595  C CD  . GLN A 1 77  ? -13.792 20.891  1.490   1.0 98.59 ? 77  GLN A CD  1 O43570 UNP 77  Q 
ATOM 596  N NE2 . GLN A 1 77  ? -14.182 21.222  2.702   1.0 98.59 ? 77  GLN A NE2 1 O43570 UNP 77  Q 
ATOM 597  O OE1 . GLN A 1 77  ? -13.369 21.769  0.749   1.0 98.59 ? 77  GLN A OE1 1 O43570 UNP 77  Q 
ATOM 598  N N   . GLY A 1 78  ? -14.666 17.909  -3.240  1.0 98.35 ? 78  GLY A N   1 O43570 UNP 78  G 
ATOM 599  C CA  . GLY A 1 78  ? -14.497 17.782  -4.694  1.0 98.35 ? 78  GLY A CA  1 O43570 UNP 78  G 
ATOM 600  C C   . GLY A 1 78  ? -14.454 16.337  -5.208  1.0 98.35 ? 78  GLY A C   1 O43570 UNP 78  G 
ATOM 601  O O   . GLY A 1 78  ? -14.067 16.119  -6.349  1.0 98.35 ? 78  GLY A O   1 O43570 UNP 78  G 
ATOM 602  N N   . TYR A 1 79  ? -14.856 15.351  -4.395  1.0 98.55 ? 79  TYR A N   1 O43570 UNP 79  Y 
ATOM 603  C CA  . TYR A 1 79  ? -14.888 13.934  -4.789  1.0 98.55 ? 79  TYR A CA  1 O43570 UNP 79  Y 
ATOM 604  C C   . TYR A 1 79  ? -16.005 13.623  -5.795  1.0 98.55 ? 79  TYR A C   1 O43570 UNP 79  Y 
ATOM 605  C CB  . TYR A 1 79  ? -15.027 13.056  -3.535  1.0 98.55 ? 79  TYR A CB  1 O43570 UNP 79  Y 
ATOM 606  O O   . TYR A 1 79  ? -15.875 12.692  -6.589  1.0 98.55 ? 79  TYR A O   1 O43570 UNP 79  Y 
ATOM 607  C CG  . TYR A 1 79  ? -13.718 12.713  -2.844  1.0 98.55 ? 79  TYR A CG  1 O43570 UNP 79  Y 
ATOM 608  C CD1 . TYR A 1 79  ? -13.453 11.375  -2.486  1.0 98.55 ? 79  TYR A CD1 1 O43570 UNP 79  Y 
ATOM 609  C CD2 . TYR A 1 79  ? -12.768 13.711  -2.539  1.0 98.55 ? 79  TYR A CD2 1 O43570 UNP 79  Y 
ATOM 610  C CE1 . TYR A 1 79  ? -12.243 11.033  -1.857  1.0 98.55 ? 79  TYR A CE1 1 O43570 UNP 79  Y 
ATOM 611  C CE2 . TYR A 1 79  ? -11.547 13.373  -1.928  1.0 98.55 ? 79  TYR A CE2 1 O43570 UNP 79  Y 
ATOM 612  O OH  . TYR A 1 79  ? -10.096 11.678  -1.044  1.0 98.55 ? 79  TYR A OH  1 O43570 UNP 79  Y 
ATOM 613  C CZ  . TYR A 1 79  ? -11.284 12.029  -1.591  1.0 98.55 ? 79  TYR A CZ  1 O43570 UNP 79  Y 
ATOM 614  N N   . ASN A 1 80  ? -17.077 14.422  -5.814  1.0 98.59 ? 80  ASN A N   1 O43570 UNP 80  N 
ATOM 615  C CA  . ASN A 1 80  ? -18.130 14.330  -6.822  1.0 98.59 ? 80  ASN A CA  1 O43570 UNP 80  N 
ATOM 616  C C   . ASN A 1 80  ? -17.690 14.981  -8.142  1.0 98.59 ? 80  ASN A C   1 O43570 UNP 80  N 
ATOM 617  C CB  . ASN A 1 80  ? -19.450 14.867  -6.256  1.0 98.59 ? 80  ASN A CB  1 O43570 UNP 80  N 
ATOM 618  O O   . ASN A 1 80  ? -17.977 16.153  -8.405  1.0 98.59 ? 80  ASN A O   1 O43570 UNP 80  N 
ATOM 619  C CG  . ASN A 1 80  ? -20.628 14.515  -7.151  1.0 98.59 ? 80  ASN A CG  1 O43570 UNP 80  N 
ATOM 620  N ND2 . ASN A 1 80  ? -21.800 15.005  -6.830  1.0 98.59 ? 80  ASN A ND2 1 O43570 UNP 80  N 
ATOM 621  O OD1 . ASN A 1 80  ? -20.537 13.782  -8.121  1.0 98.59 ? 80  ASN A OD1 1 O43570 UNP 80  N 
ATOM 622  N N   . LEU A 1 81  ? -16.944 14.228  -8.953  1.0 98.38 ? 81  LEU A N   1 O43570 UNP 81  L 
ATOM 623  C CA  . LEU A 1 81  ? -16.379 14.721  -10.204 1.0 98.38 ? 81  LEU A CA  1 O43570 UNP 81  L 
ATOM 624  C C   . LEU A 1 81  ? -17.475 14.959  -11.249 1.0 98.38 ? 81  LEU A C   1 O43570 UNP 81  L 
ATOM 625  C CB  . LEU A 1 81  ? -15.318 13.746  -10.741 1.0 98.38 ? 81  LEU A CB  1 O43570 UNP 81  L 
ATOM 626  O O   . LEU A 1 81  ? -18.381 14.152  -11.435 1.0 98.38 ? 81  LEU A O   1 O43570 UNP 81  L 
ATOM 627  C CG  . LEU A 1 81  ? -14.169 13.415  -9.772  1.0 98.38 ? 81  LEU A CG  1 O43570 UNP 81  L 
ATOM 628  C CD1 . LEU A 1 81  ? -13.231 12.394  -10.415 1.0 98.38 ? 81  LEU A CD1 1 O43570 UNP 81  L 
ATOM 629  C CD2 . LEU A 1 81  ? -13.355 14.655  -9.409  1.0 98.38 ? 81  LEU A CD2 1 O43570 UNP 81  L 
ATOM 630  N N   . SER A 1 82  ? -17.356 16.059  -11.994 1.0 97.19 ? 82  SER A N   1 O43570 UNP 82  S 
ATOM 631  C CA  . SER A 1 82  ? -18.314 16.401  -13.050 1.0 97.19 ? 82  SER A CA  1 O43570 UNP 82  S 
ATOM 632  C C   . SER A 1 82  ? -18.363 15.329  -14.141 1.0 97.19 ? 82  SER A C   1 O43570 UNP 82  S 
ATOM 633  C CB  . SER A 1 82  ? -17.943 17.751  -13.667 1.0 97.19 ? 82  SER A CB  1 O43570 UNP 82  S 
ATOM 634  O O   . SER A 1 82  ? -17.356 15.086  -14.804 1.0 97.19 ? 82  SER A O   1 O43570 UNP 82  S 
ATOM 635  O OG  . SER A 1 82  ? -18.847 18.109  -14.698 1.0 97.19 ? 82  SER A OG  1 O43570 UNP 82  S 
ATOM 636  N N   . ALA A 1 83  ? -19.549 14.776  -14.405 1.0 97.42 ? 83  ALA A N   1 O43570 UNP 83  A 
ATOM 637  C CA  . ALA A 1 83  ? -19.783 13.819  -15.493 1.0 97.42 ? 83  ALA A CA  1 O43570 UNP 83  A 
ATOM 638  C C   . ALA A 1 83  ? -19.469 14.381  -16.896 1.0 97.42 ? 83  ALA A C   1 O43570 UNP 83  A 
ATOM 639  C CB  . ALA A 1 83  ? -21.237 13.340  -15.395 1.0 97.42 ? 83  ALA A CB  1 O43570 UNP 83  A 
ATOM 640  O O   . ALA A 1 83  ? -19.270 13.621  -17.839 1.0 97.42 ? 83  ALA A O   1 O43570 UNP 83  A 
ATOM 641  N N   . ASN A 1 84  ? -19.380 15.711  -17.036 1.0 97.58 ? 84  ASN A N   1 O43570 UNP 84  N 
ATOM 642  C CA  . ASN A 1 84  ? -18.976 16.383  -18.276 1.0 97.58 ? 84  ASN A CA  1 O43570 UNP 84  N 
ATOM 643  C C   . ASN A 1 84  ? -17.449 16.453  -18.462 1.0 97.58 ? 84  ASN A C   1 O43570 UNP 84  N 
ATOM 644  C CB  . ASN A 1 84  ? -19.585 17.795  -18.296 1.0 97.58 ? 84  ASN A CB  1 O43570 UNP 84  N 
ATOM 645  O O   . ASN A 1 84  ? -16.977 16.899  -19.507 1.0 97.58 ? 84  ASN A O   1 O43570 UNP 84  N 
ATOM 646  C CG  . ASN A 1 84  ? -21.101 17.786  -18.341 1.0 97.58 ? 84  ASN A CG  1 O43570 UNP 84  N 
ATOM 647  N ND2 . ASN A 1 84  ? -21.748 18.685  -17.639 1.0 97.58 ? 84  ASN A ND2 1 O43570 UNP 84  N 
ATOM 648  O OD1 . ASN A 1 84  ? -21.733 16.990  -19.008 1.0 97.58 ? 84  ASN A OD1 1 O43570 UNP 84  N 
ATOM 649  N N   . LYS A 1 85  ? -16.667 16.070  -17.447 1.0 97.96 ? 85  LYS A N   1 O43570 UNP 85  K 
ATOM 650  C CA  . LYS A 1 85  ? -15.211 15.932  -17.529 1.0 97.96 ? 85  LYS A CA  1 O43570 UNP 85  K 
ATOM 651  C C   . LYS A 1 85  ? -14.838 14.467  -17.735 1.0 97.96 ? 85  LYS A C   1 O43570 UNP 85  K 
ATOM 652  C CB  . LYS A 1 85  ? -14.536 16.503  -16.274 1.0 97.96 ? 85  LYS A CB  1 O43570 UNP 85  K 
ATOM 653  O O   . LYS A 1 85  ? -15.528 13.563  -17.273 1.0 97.96 ? 85  LYS A O   1 O43570 UNP 85  K 
ATOM 654  C CG  . LYS A 1 85  ? -14.431 18.036  -16.287 1.0 97.96 ? 85  LYS A CG  1 O43570 UNP 85  K 
ATOM 655  C CD  . LYS A 1 85  ? -13.663 18.506  -15.038 1.0 97.96 ? 85  LYS A CD  1 O43570 UNP 85  K 
ATOM 656  C CE  . LYS A 1 85  ? -13.001 19.876  -15.228 1.0 97.96 ? 85  LYS A CE  1 O43570 UNP 85  K 
ATOM 657  N NZ  . LYS A 1 85  ? -12.171 20.235  -14.042 1.0 97.96 ? 85  LYS A NZ  1 O43570 UNP 85  K 
ATOM 658  N N   . GLN A 1 86  ? -13.712 14.257  -18.405 1.0 98.34 ? 86  GLN A N   1 O43570 UNP 86  Q 
ATOM 659  C CA  . GLN A 1 86  ? -13.103 12.948  -18.600 1.0 98.34 ? 86  GLN A CA  1 O43570 UNP 86  Q 
ATOM 660  C C   . GLN A 1 86  ? -11.780 12.868  -17.842 1.0 98.34 ? 86  GLN A C   1 O43570 UNP 86  Q 
ATOM 661  C CB  . GLN A 1 86  ? -12.896 12.690  -20.095 1.0 98.34 ? 86  GLN A CB  1 O43570 UNP 86  Q 
ATOM 662  O O   . GLN A 1 86  ? -11.019 13.837  -17.804 1.0 98.34 ? 86  GLN A O   1 O43570 UNP 86  Q 
ATOM 663  C CG  . GLN A 1 86  ? -14.223 12.454  -20.830 1.0 98.34 ? 86  GLN A CG  1 O43570 UNP 86  Q 
ATOM 664  C CD  . GLN A 1 86  ? -14.020 12.133  -22.307 1.0 98.34 ? 86  GLN A CD  1 O43570 UNP 86  Q 
ATOM 665  N NE2 . GLN A 1 86  ? -14.904 11.369  -22.910 1.0 98.34 ? 86  GLN A NE2 1 O43570 UNP 86  Q 
ATOM 666  O OE1 . GLN A 1 86  ? -13.081 12.561  -22.954 1.0 98.34 ? 86  GLN A OE1 1 O43570 UNP 86  Q 
ATOM 667  N N   . PHE A 1 87  ? -11.509 11.703  -17.267 1.0 98.73 ? 87  PHE A N   1 O43570 UNP 87  F 
ATOM 668  C CA  . PHE A 1 87  ? -10.323 11.413  -16.472 1.0 98.73 ? 87  PHE A CA  1 O43570 UNP 87  F 
ATOM 669  C C   . PHE A 1 87  ? -9.528  10.284  -17.124 1.0 98.73 ? 87  PHE A C   1 O43570 UNP 87  F 
ATOM 670  C CB  . PHE A 1 87  ? -10.754 11.093  -15.037 1.0 98.73 ? 87  PHE A CB  1 O43570 UNP 87  F 
ATOM 671  O O   . PHE A 1 87  ? -10.104 9.325   -17.638 1.0 98.73 ? 87  PHE A O   1 O43570 UNP 87  F 
ATOM 672  C CG  . PHE A 1 87  ? -11.408 12.281  -14.364 1.0 98.73 ? 87  PHE A CG  1 O43570 UNP 87  F 
ATOM 673  C CD1 . PHE A 1 87  ? -10.611 13.272  -13.767 1.0 98.73 ? 87  PHE A CD1 1 O43570 UNP 87  F 
ATOM 674  C CD2 . PHE A 1 87  ? -12.803 12.456  -14.437 1.0 98.73 ? 87  PHE A CD2 1 O43570 UNP 87  F 
ATOM 675  C CE1 . PHE A 1 87  ? -11.207 14.438  -13.262 1.0 98.73 ? 87  PHE A CE1 1 O43570 UNP 87  F 
ATOM 676  C CE2 . PHE A 1 87  ? -13.396 13.622  -13.923 1.0 98.73 ? 87  PHE A CE2 1 O43570 UNP 87  F 
ATOM 677  C CZ  . PHE A 1 87  ? -12.599 14.610  -13.323 1.0 98.73 ? 87  PHE A CZ  1 O43570 UNP 87  F 
ATOM 678  N N   . LEU A 1 88  ? -8.204  10.430  -17.151 1.0 98.80 ? 88  LEU A N   1 O43570 UNP 88  L 
ATOM 679  C CA  . LEU A 1 88  ? -7.313  9.513   -17.858 1.0 98.80 ? 88  LEU A CA  1 O43570 UNP 88  L 
ATOM 680  C C   . LEU A 1 88  ? -7.063  8.259   -17.017 1.0 98.80 ? 88  LEU A C   1 O43570 UNP 88  L 
ATOM 681  C CB  . LEU A 1 88  ? -6.005  10.250  -18.193 1.0 98.80 ? 88  LEU A CB  1 O43570 UNP 88  L 
ATOM 682  O O   . LEU A 1 88  ? -6.461  8.347   -15.945 1.0 98.80 ? 88  LEU A O   1 O43570 UNP 88  L 
ATOM 683  C CG  . LEU A 1 88  ? -5.078  9.471   -19.143 1.0 98.80 ? 88  LEU A CG  1 O43570 UNP 88  L 
ATOM 684  C CD1 . LEU A 1 88  ? -5.685  9.398   -20.544 1.0 98.80 ? 88  LEU A CD1 1 O43570 UNP 88  L 
ATOM 685  C CD2 . LEU A 1 88  ? -3.734  10.195  -19.217 1.0 98.80 ? 88  LEU A CD2 1 O43570 UNP 88  L 
ATOM 686  N N   . LEU A 1 89  ? -7.511  7.112   -17.514 1.0 98.90 ? 89  LEU A N   1 O43570 UNP 89  L 
ATOM 687  C CA  . LEU A 1 89  ? -7.187  5.787   -17.005 1.0 98.90 ? 89  LEU A CA  1 O43570 UNP 89  L 
ATOM 688  C C   . LEU A 1 89  ? -5.993  5.243   -17.789 1.0 98.90 ? 89  LEU A C   1 O43570 UNP 89  L 
ATOM 689  C CB  . LEU A 1 89  ? -8.420  4.882   -17.158 1.0 98.90 ? 89  LEU A CB  1 O43570 UNP 89  L 
ATOM 690  O O   . LEU A 1 89  ? -6.030  5.211   -19.015 1.0 98.90 ? 89  LEU A O   1 O43570 UNP 89  L 
ATOM 691  C CG  . LEU A 1 89  ? -8.321  3.540   -16.411 1.0 98.90 ? 89  LEU A CG  1 O43570 UNP 89  L 
ATOM 692  C CD1 . LEU A 1 89  ? -8.490  3.753   -14.906 1.0 98.90 ? 89  LEU A CD1 1 O43570 UNP 89  L 
ATOM 693  C CD2 . LEU A 1 89  ? -9.428  2.599   -16.881 1.0 98.90 ? 89  LEU A CD2 1 O43570 UNP 89  L 
ATOM 694  N N   . THR A 1 90  ? -4.955  4.789   -17.100 1.0 98.79 ? 90  THR A N   1 O43570 UNP 90  T 
ATOM 695  C CA  . THR A 1 90  ? -3.721  4.296   -17.719 1.0 98.79 ? 90  THR A CA  1 O43570 UNP 90  T 
ATOM 696  C C   . THR A 1 90  ? -3.322  2.968   -17.095 1.0 98.79 ? 90  THR A C   1 O43570 UNP 90  T 
ATOM 697  C CB  . THR A 1 90  ? -2.569  5.299   -17.533 1.0 98.79 ? 90  THR A CB  1 O43570 UNP 90  T 
ATOM 698  O O   . THR A 1 90  ? -3.256  2.851   -15.870 1.0 98.79 ? 90  THR A O   1 O43570 UNP 90  T 
ATOM 699  C CG2 . THR A 1 90  ? -1.307  4.912   -18.304 1.0 98.79 ? 90  THR A CG2 1 O43570 UNP 90  T 
ATOM 700  O OG1 . THR A 1 90  ? -2.906  6.607   -17.930 1.0 98.79 ? 90  THR A OG1 1 O43570 UNP 90  T 
ATOM 701  N N   . ASN A 1 91  ? -2.955  1.992   -17.922 1.0 98.67 ? 91  ASN A N   1 O43570 UNP 91  N 
ATOM 702  C CA  . ASN A 1 91  ? -2.165  0.851   -17.465 1.0 98.67 ? 91  ASN A CA  1 O43570 UNP 91  N 
ATOM 703  C C   . ASN A 1 91  ? -0.683  1.234   -17.512 1.0 98.67 ? 91  ASN A C   1 O43570 UNP 91  N 
ATOM 704  C CB  . ASN A 1 91  ? -2.533  -0.376  -18.304 1.0 98.67 ? 91  ASN A CB  1 O43570 UNP 91  N 
ATOM 705  O O   . ASN A 1 91  ? -0.094  1.396   -18.581 1.0 98.67 ? 91  ASN A O   1 O43570 UNP 91  N 
ATOM 706  C CG  . ASN A 1 91  ? -1.683  -1.607  -18.042 1.0 98.67 ? 91  ASN A CG  1 O43570 UNP 91  N 
ATOM 707  N ND2 . ASN A 1 91  ? -2.130  -2.749  -18.494 1.0 98.67 ? 91  ASN A ND2 1 O43570 UNP 91  N 
ATOM 708  O OD1 . ASN A 1 91  ? -0.605  -1.555  -17.468 1.0 98.67 ? 91  ASN A OD1 1 O43570 UNP 91  N 
ATOM 709  N N   . ASN A 1 92  ? -0.064  1.395   -16.344 1.0 97.89 ? 92  ASN A N   1 O43570 UNP 92  N 
ATOM 710  C CA  . ASN A 1 92  ? 1.341   1.807   -16.241 1.0 97.89 ? 92  ASN A CA  1 O43570 UNP 92  N 
ATOM 711  C C   . ASN A 1 92  ? 2.327   0.619   -16.189 1.0 97.89 ? 92  ASN A C   1 O43570 UNP 92  N 
ATOM 712  C CB  . ASN A 1 92  ? 1.485   2.796   -15.071 1.0 97.89 ? 92  ASN A CB  1 O43570 UNP 92  N 
ATOM 713  O O   . ASN A 1 92  ? 3.529   0.823   -16.011 1.0 97.89 ? 92  ASN A O   1 O43570 UNP 92  N 
ATOM 714  C CG  . ASN A 1 92  ? 1.271   2.160   -13.709 1.0 97.89 ? 92  ASN A CG  1 O43570 UNP 92  N 
ATOM 715  N ND2 . ASN A 1 92  ? 1.132   2.945   -12.669 1.0 97.89 ? 92  ASN A ND2 1 O43570 UNP 92  N 
ATOM 716  O OD1 . ASN A 1 92  ? 1.247   0.955   -13.549 1.0 97.89 ? 92  ASN A OD1 1 O43570 UNP 92  N 
ATOM 717  N N   . GLY A 1 93  ? 1.833   -0.612  -16.345 1.0 97.84 ? 93  GLY A N   1 O43570 UNP 93  G 
ATOM 718  C CA  . GLY A 1 93  ? 2.605   -1.850  -16.249 1.0 97.84 ? 93  GLY A CA  1 O43570 UNP 93  G 
ATOM 719  C C   . GLY A 1 93  ? 2.771   -2.399  -14.828 1.0 97.84 ? 93  GLY A C   1 O43570 UNP 93  G 
ATOM 720  O O   . GLY A 1 93  ? 3.375   -3.456  -14.670 1.0 97.84 ? 93  GLY A O   1 O43570 UNP 93  G 
ATOM 721  N N   . HIS A 1 94  ? 2.243   -1.710  -13.815 1.0 98.09 ? 94  HIS A N   1 O43570 UNP 94  H 
ATOM 722  C CA  . HIS A 1 94  ? 2.283   -2.119  -12.404 1.0 98.09 ? 94  HIS A CA  1 O43570 UNP 94  H 
ATOM 723  C C   . HIS A 1 94  ? 0.898   -2.111  -11.746 1.0 98.09 ? 94  HIS A C   1 O43570 UNP 94  H 
ATOM 724  C CB  . HIS A 1 94  ? 3.214   -1.173  -11.635 1.0 98.09 ? 94  HIS A CB  1 O43570 UNP 94  H 
ATOM 725  O O   . HIS A 1 94  ? 0.654   -2.862  -10.809 1.0 98.09 ? 94  HIS A O   1 O43570 UNP 94  H 
ATOM 726  C CG  . HIS A 1 94  ? 4.580   -1.028  -12.251 1.0 98.09 ? 94  HIS A CG  1 O43570 UNP 94  H 
ATOM 727  C CD2 . HIS A 1 94  ? 5.076   0.080   -12.880 1.0 98.09 ? 94  HIS A CD2 1 O43570 UNP 94  H 
ATOM 728  N ND1 . HIS A 1 94  ? 5.545   -2.000  -12.318 1.0 98.09 ? 94  HIS A ND1 1 O43570 UNP 94  H 
ATOM 729  C CE1 . HIS A 1 94  ? 6.597   -1.489  -12.973 1.0 98.09 ? 94  HIS A CE1 1 O43570 UNP 94  H 
ATOM 730  N NE2 . HIS A 1 94  ? 6.367   -0.213  -13.331 1.0 98.09 ? 94  HIS A NE2 1 O43570 UNP 94  H 
ATOM 731  N N   . SER A 1 95  ? 0.001   -1.252  -12.224 1.0 98.65 ? 95  SER A N   1 O43570 UNP 95  S 
ATOM 732  C CA  . SER A 1 95  ? -1.396  -1.166  -11.817 1.0 98.65 ? 95  SER A CA  1 O43570 UNP 95  S 
ATOM 733  C C   . SER A 1 95  ? -2.205  -0.469  -12.921 1.0 98.65 ? 95  SER A C   1 O43570 UNP 95  S 
ATOM 734  C CB  . SER A 1 95  ? -1.486  -0.411  -10.483 1.0 98.65 ? 95  SER A CB  1 O43570 UNP 95  S 
ATOM 735  O O   . SER A 1 95  ? -1.650  0.071   -13.890 1.0 98.65 ? 95  SER A O   1 O43570 UNP 95  S 
ATOM 736  O OG  . SER A 1 95  ? -2.815  -0.390  -10.018 1.0 98.65 ? 95  SER A OG  1 O43570 UNP 95  S 
ATOM 737  N N   . VAL A 1 96  ? -3.524  -0.447  -12.753 1.0 98.65 ? 96  VAL A N   1 O43570 UNP 96  V 
ATOM 738  C CA  . VAL A 1 96  ? -4.415  0.478   -13.447 1.0 98.65 ? 96  VAL A CA  1 O43570 UNP 96  V 
ATOM 739  C C   . VAL A 1 96  ? -4.584  1.737   -12.598 1.0 98.65 ? 96  VAL A C   1 O43570 UNP 96  V 
ATOM 740  C CB  . VAL A 1 96  ? -5.743  -0.202  -13.809 1.0 98.65 ? 96  VAL A CB  1 O43570 UNP 96  V 
ATOM 741  O O   . VAL A 1 96  ? -4.926  1.671   -11.420 1.0 98.65 ? 96  VAL A O   1 O43570 UNP 96  V 
ATOM 742  C CG1 . VAL A 1 96  ? -6.557  -0.682  -12.600 1.0 98.65 ? 96  VAL A CG1 1 O43570 UNP 96  V 
ATOM 743  C CG2 . VAL A 1 96  ? -6.583  0.750   -14.657 1.0 98.65 ? 96  VAL A CG2 1 O43570 UNP 96  V 
ATOM 744  N N   . LYS A 1 97  ? -4.314  2.899   -13.194 1.0 98.79 ? 97  LYS A N   1 O43570 UNP 97  K 
ATOM 745  C CA  . LYS A 1 97  ? -4.285  4.191   -12.506 1.0 98.79 ? 97  LYS A CA  1 O43570 UNP 97  K 
ATOM 746  C C   . LYS A 1 97  ? -5.251  5.167   -13.164 1.0 98.79 ? 97  LYS A C   1 O43570 UNP 97  K 
ATOM 747  C CB  . LYS A 1 97  ? -2.845  4.715   -12.526 1.0 98.79 ? 97  LYS A CB  1 O43570 UNP 97  K 
ATOM 748  O O   . LYS A 1 97  ? -5.126  5.414   -14.360 1.0 98.79 ? 97  LYS A O   1 O43570 UNP 97  K 
ATOM 749  C CG  . LYS A 1 97  ? -2.698  6.045   -11.768 1.0 98.79 ? 97  LYS A CG  1 O43570 UNP 97  K 
ATOM 750  C CD  . LYS A 1 97  ? -1.398  6.784   -12.101 1.0 98.79 ? 97  LYS A CD  1 O43570 UNP 97  K 
ATOM 751  C CE  . LYS A 1 97  ? -1.416  7.204   -13.577 1.0 98.79 ? 97  LYS A CE  1 O43570 UNP 97  K 
ATOM 752  N NZ  . LYS A 1 97  ? -0.457  8.289   -13.866 1.0 98.79 ? 97  LYS A NZ  1 O43570 UNP 97  K 
ATOM 753  N N   . LEU A 1 98  ? -6.141  5.776   -12.388 1.0 98.85 ? 98  LEU A N   1 O43570 UNP 98  L 
ATOM 754  C CA  . LEU A 1 98  ? -7.003  6.874   -12.825 1.0 98.85 ? 98  LEU A CA  1 O43570 UNP 98  L 
ATOM 755  C C   . LEU A 1 98  ? -6.431  8.201   -12.317 1.0 98.85 ? 98  LEU A C   1 O43570 UNP 98  L 
ATOM 756  C CB  . LEU A 1 98  ? -8.428  6.619   -12.307 1.0 98.85 ? 98  LEU A CB  1 O43570 UNP 98  L 
ATOM 757  O O   . LEU A 1 98  ? -6.262  8.378   -11.112 1.0 98.85 ? 98  LEU A O   1 O43570 UNP 98  L 
ATOM 758  C CG  . LEU A 1 98  ? -9.475  7.657   -12.747 1.0 98.85 ? 98  LEU A CG  1 O43570 UNP 98  L 
ATOM 759  C CD1 . LEU A 1 98  ? -9.725  7.594   -14.254 1.0 98.85 ? 98  LEU A CD1 1 O43570 UNP 98  L 
ATOM 760  C CD2 . LEU A 1 98  ? -10.797 7.393   -12.029 1.0 98.85 ? 98  LEU A CD2 1 O43570 UNP 98  L 
ATOM 761  N N   . ASN A 1 99  ? -6.128  9.138   -13.213 1.0 98.80 ? 99  ASN A N   1 O43570 UNP 99  N 
ATOM 762  C CA  . ASN A 1 99  ? -5.701  10.482  -12.823 1.0 98.80 ? 99  ASN A CA  1 O43570 UNP 99  N 
ATOM 763  C C   . ASN A 1 99  ? -6.876  11.257  -12.209 1.0 98.80 ? 99  ASN A C   1 O43570 UNP 99  N 
ATOM 764  C CB  . ASN A 1 99  ? -5.126  11.235  -14.031 1.0 98.80 ? 99  ASN A CB  1 O43570 UNP 99  N 
ATOM 765  O O   . ASN A 1 99  ? -7.972  11.280  -12.768 1.0 98.80 ? 99  ASN A O   1 O43570 UNP 99  N 
ATOM 766  C CG  . ASN A 1 99  ? -3.750  10.778  -14.493 1.0 98.80 ? 99  ASN A CG  1 O43570 UNP 99  N 
ATOM 767  N ND2 . ASN A 1 99  ? -3.293  11.350  -15.584 1.0 98.80 ? 99  ASN A ND2 1 O43570 UNP 99  N 
ATOM 768  O OD1 . ASN A 1 99  ? -3.046  9.962   -13.906 1.0 98.80 ? 99  ASN A OD1 1 O43570 UNP 99  N 
ATOM 769  N N   . LEU A 1 100 ? -6.621  11.941  -11.096 1.0 98.83 ? 100 LEU A N   1 O43570 UNP 100 L 
ATOM 770  C CA  . LEU A 1 100 ? -7.599  12.751  -10.372 1.0 98.83 ? 100 LEU A CA  1 O43570 UNP 100 L 
ATOM 771  C C   . LEU A 1 100 ? -7.199  14.229  -10.420 1.0 98.83 ? 100 LEU A C   1 O43570 UNP 100 L 
ATOM 772  C CB  . LEU A 1 100 ? -7.719  12.252  -8.926  1.0 98.83 ? 100 LEU A CB  1 O43570 UNP 100 L 
ATOM 773  O O   . LEU A 1 100 ? -6.008  14.536  -10.529 1.0 98.83 ? 100 LEU A O   1 O43570 UNP 100 L 
ATOM 774  C CG  . LEU A 1 100 ? -8.268  10.821  -8.798  1.0 98.83 ? 100 LEU A CG  1 O43570 UNP 100 L 
ATOM 775  C CD1 . LEU A 1 100 ? -8.174  10.408  -7.334  1.0 98.83 ? 100 LEU A CD1 1 O43570 UNP 100 L 
ATOM 776  C CD2 . LEU A 1 100 ? -9.723  10.707  -9.258  1.0 98.83 ? 100 LEU A CD2 1 O43570 UNP 100 L 
ATOM 777  N N   . PRO A 1 101 ? -8.164  15.158  -10.374 1.0 98.53 ? 101 PRO A N   1 O43570 UNP 101 P 
ATOM 778  C CA  . PRO A 1 101 ? -7.866  16.570  -10.513 1.0 98.53 ? 101 PRO A CA  1 O43570 UNP 101 P 
ATOM 779  C C   . PRO A 1 101 ? -7.510  17.187  -9.151  1.0 98.53 ? 101 PRO A C   1 O43570 UNP 101 P 
ATOM 780  C CB  . PRO A 1 101 ? -9.137  17.117  -11.141 1.0 98.53 ? 101 PRO A CB  1 O43570 UNP 101 P 
ATOM 781  O O   . PRO A 1 101 ? -7.996  16.751  -8.112  1.0 98.53 ? 101 PRO A O   1 O43570 UNP 101 P 
ATOM 782  C CG  . PRO A 1 101 ? -10.228 16.361  -10.375 1.0 98.53 ? 101 PRO A CG  1 O43570 UNP 101 P 
ATOM 783  C CD  . PRO A 1 101 ? -9.605  14.967  -10.202 1.0 98.53 ? 101 PRO A CD  1 O43570 UNP 101 P 
ATOM 784  N N   . SER A 1 102 ? -6.671  18.223  -9.142  1.0 98.26 ? 102 SER A N   1 O43570 UNP 102 S 
ATOM 785  C CA  . SER A 1 102 ? -6.149  18.813  -7.900  1.0 98.26 ? 102 SER A CA  1 O43570 UNP 102 S 
ATOM 786  C C   . SER A 1 102 ? -7.163  19.661  -7.118  1.0 98.26 ? 102 SER A C   1 O43570 UNP 102 S 
ATOM 787  C CB  . SER A 1 102 ? -4.898  19.638  -8.216  1.0 98.26 ? 102 SER A CB  1 O43570 UNP 102 S 
ATOM 788  O O   . SER A 1 102 ? -6.855  20.101  -6.018  1.0 98.26 ? 102 SER A O   1 O43570 UNP 102 S 
ATOM 789  O OG  . SER A 1 102 ? -5.220  20.682  -9.122  1.0 98.26 ? 102 SER A OG  1 O43570 UNP 102 S 
ATOM 790  N N   . ASP A 1 103 ? -8.351  19.942  -7.665  1.0 97.82 ? 103 ASP A N   1 O43570 UNP 103 D 
ATOM 791  C CA  . ASP A 1 103 ? -9.456  20.560  -6.916  1.0 97.82 ? 103 ASP A CA  1 O43570 UNP 103 D 
ATOM 792  C C   . ASP A 1 103 ? -10.138 19.576  -5.949  1.0 97.82 ? 103 ASP A C   1 O43570 UNP 103 D 
ATOM 793  C CB  . ASP A 1 103 ? -10.460 21.238  -7.874  1.0 97.82 ? 103 ASP A CB  1 O43570 UNP 103 D 
ATOM 794  O O   . ASP A 1 103 ? -10.699 19.998  -4.933  1.0 97.82 ? 103 ASP A O   1 O43570 UNP 103 D 
ATOM 795  C CG  . ASP A 1 103 ? -11.049 20.344  -8.977  1.0 97.82 ? 103 ASP A CG  1 O43570 UNP 103 D 
ATOM 796  O OD1 . ASP A 1 103 ? -10.254 19.691  -9.685  1.0 97.82 ? 103 ASP A OD1 1 O43570 UNP 103 D 
ATOM 797  O OD2 . ASP A 1 103 ? -12.273 20.411  -9.226  1.0 97.82 ? 103 ASP A OD2 1 O43570 UNP 103 D 
ATOM 798  N N   . MET A 1 104 ? -10.024 18.270  -6.211  1.0 98.76 ? 104 MET A N   1 O43570 UNP 104 M 
ATOM 799  C CA  . MET A 1 104 ? -10.395 17.209  -5.276  1.0 98.76 ? 104 MET A CA  1 O43570 UNP 104 M 
ATOM 800  C C   . MET A 1 104 ? -9.344  17.124  -4.161  1.0 98.76 ? 104 MET A C   1 O43570 UNP 104 M 
ATOM 801  C CB  . MET A 1 104 ? -10.515 15.897  -6.064  1.0 98.76 ? 104 MET A CB  1 O43570 UNP 104 M 
ATOM 802  O O   . MET A 1 104 ? -8.155  17.011  -4.448  1.0 98.76 ? 104 MET A O   1 O43570 UNP 104 M 
ATOM 803  C CG  . MET A 1 104 ? -10.866 14.680  -5.214  1.0 98.76 ? 104 MET A CG  1 O43570 UNP 104 M 
ATOM 804  S SD  . MET A 1 104 ? -10.775 13.146  -6.174  1.0 98.76 ? 104 MET A SD  1 O43570 UNP 104 M 
ATOM 805  C CE  . MET A 1 104 ? -10.757 11.942  -4.828  1.0 98.76 ? 104 MET A CE  1 O43570 UNP 104 M 
ATOM 806  N N   . HIS A 1 105 ? -9.743  17.180  -2.889  1.0 98.77 ? 105 HIS A N   1 O43570 UNP 105 H 
ATOM 807  C CA  . HIS A 1 105 ? -8.803  17.191  -1.765  1.0 98.77 ? 105 HIS A CA  1 O43570 UNP 105 H 
ATOM 808  C C   . HIS A 1 105 ? -9.403  16.660  -0.459  1.0 98.77 ? 105 HIS A C   1 O43570 UNP 105 H 
ATOM 809  C CB  . HIS A 1 105 ? -8.242  18.612  -1.573  1.0 98.77 ? 105 HIS A CB  1 O43570 UNP 105 H 
ATOM 810  O O   . HIS A 1 105 ? -10.619 16.612  -0.277  1.0 98.77 ? 105 HIS A O   1 O43570 UNP 105 H 
ATOM 811  C CG  . HIS A 1 105 ? -9.254  19.640  -1.149  1.0 98.77 ? 105 HIS A CG  1 O43570 UNP 105 H 
ATOM 812  C CD2 . HIS A 1 105 ? -9.459  20.098  0.125   1.0 98.77 ? 105 HIS A CD2 1 O43570 UNP 105 H 
ATOM 813  N ND1 . HIS A 1 105 ? -10.100 20.336  -1.982  1.0 98.77 ? 105 HIS A ND1 1 O43570 UNP 105 H 
ATOM 814  C CE1 . HIS A 1 105 ? -10.793 21.202  -1.224  1.0 98.77 ? 105 HIS A CE1 1 O43570 UNP 105 H 
ATOM 815  N NE2 . HIS A 1 105 ? -10.400 21.129  0.060   1.0 98.77 ? 105 HIS A NE2 1 O43570 UNP 105 H 
ATOM 816  N N   . ILE A 1 106 ? -8.523  16.285  0.470   1.0 98.61 ? 106 ILE A N   1 O43570 UNP 106 I 
ATOM 817  C CA  . ILE A 1 106 ? -8.878  15.933  1.847   1.0 98.61 ? 106 ILE A CA  1 O43570 UNP 106 I 
ATOM 818  C C   . ILE A 1 106 ? -8.778  17.179  2.724   1.0 98.61 ? 106 ILE A C   1 O43570 UNP 106 I 
ATOM 819  C CB  . ILE A 1 106 ? -7.979  14.802  2.389   1.0 98.61 ? 106 ILE A CB  1 O43570 UNP 106 I 
ATOM 820  O O   . ILE A 1 106 ? -7.761  17.880  2.713   1.0 98.61 ? 106 ILE A O   1 O43570 UNP 106 I 
ATOM 821  C CG1 . ILE A 1 106 ? -8.156  13.513  1.561   1.0 98.61 ? 106 ILE A CG1 1 O43570 UNP 106 I 
ATOM 822  C CG2 . ILE A 1 106 ? -8.285  14.509  3.873   1.0 98.61 ? 106 ILE A CG2 1 O43570 UNP 106 I 
ATOM 823  C CD1 . ILE A 1 106 ? -7.000  12.530  1.773   1.0 98.61 ? 106 ILE A CD1 1 O43570 UNP 106 I 
ATOM 824  N N   . GLN A 1 107 ? -9.812  17.392  3.529   1.0 95.63 ? 107 GLN A N   1 O43570 UNP 107 Q 
ATOM 825  C CA  . GLN A 1 107 ? -9.840  18.327  4.646   1.0 95.63 ? 107 GLN A CA  1 O43570 UNP 107 Q 
ATOM 826  C C   . GLN A 1 107 ? -9.902  17.528  5.970   1.0 95.63 ? 107 GLN A C   1 O43570 UNP 107 Q 
ATOM 827  C CB  . GLN A 1 107 ? -11.001 19.304  4.389   1.0 95.63 ? 107 GLN A CB  1 O43570 UNP 107 Q 
ATOM 828  O O   . GLN A 1 107 ? -10.367 16.388  5.999   1.0 95.63 ? 107 GLN A O   1 O43570 UNP 107 Q 
ATOM 829  C CG  . GLN A 1 107 ? -11.158 20.441  5.406   1.0 95.63 ? 107 GLN A CG  1 O43570 UNP 107 Q 
ATOM 830  C CD  . GLN A 1 107 ? -10.136 21.559  5.224   1.0 95.63 ? 107 GLN A CD  1 O43570 UNP 107 Q 
ATOM 831  N NE2 . GLN A 1 107 ? -10.052 22.473  6.163   1.0 95.63 ? 107 GLN A NE2 1 O43570 UNP 107 Q 
ATOM 832  O OE1 . GLN A 1 107 ? -9.400  21.650  4.252   1.0 95.63 ? 107 GLN A OE1 1 O43570 UNP 107 Q 
ATOM 833  N N   . GLY A 1 108 ? -9.361  18.088  7.059   1.0 94.64 ? 108 GLY A N   1 O43570 UNP 108 G 
ATOM 834  C CA  . GLY A 1 108 ? -9.245  17.414  8.368   1.0 94.64 ? 108 GLY A CA  1 O43570 UNP 108 G 
ATOM 835  C C   . GLY A 1 108 ? -7.827  16.938  8.722   1.0 94.64 ? 108 GLY A C   1 O43570 UNP 108 G 
ATOM 836  O O   . GLY A 1 108 ? -7.591  16.434  9.818   1.0 94.64 ? 108 GLY A O   1 O43570 UNP 108 G 
ATOM 837  N N   . LEU A 1 109 ? -6.860  17.129  7.820   1.0 96.52 ? 109 LEU A N   1 O43570 UNP 109 L 
ATOM 838  C CA  . LEU A 1 109 ? -5.426  17.007  8.103   1.0 96.52 ? 109 LEU A CA  1 O43570 UNP 109 L 
ATOM 839  C C   . LEU A 1 109 ? -4.817  18.393  8.387   1.0 96.52 ? 109 LEU A C   1 O43570 UNP 109 L 
ATOM 840  C CB  . LEU A 1 109 ? -4.735  16.282  6.930   1.0 96.52 ? 109 LEU A CB  1 O43570 UNP 109 L 
ATOM 841  O O   . LEU A 1 109 ? -5.455  19.416  8.155   1.0 96.52 ? 109 LEU A O   1 O43570 UNP 109 L 
ATOM 842  C CG  . LEU A 1 109 ? -5.274  14.867  6.635   1.0 96.52 ? 109 LEU A CG  1 O43570 UNP 109 L 
ATOM 843  C CD1 . LEU A 1 109 ? -4.520  14.271  5.446   1.0 96.52 ? 109 LEU A CD1 1 O43570 UNP 109 L 
ATOM 844  C CD2 . LEU A 1 109 ? -5.123  13.924  7.832   1.0 96.52 ? 109 LEU A CD2 1 O43570 UNP 109 L 
ATOM 845  N N   . GLN A 1 110 ? -3.573  18.435  8.880   1.0 95.39 ? 110 GLN A N   1 O43570 UNP 110 Q 
ATOM 846  C CA  . GLN A 1 110 ? -2.885  19.696  9.205   1.0 95.39 ? 110 GLN A CA  1 O43570 UNP 110 Q 
ATOM 847  C C   . GLN A 1 110 ? -2.686  20.619  7.987   1.0 95.39 ? 110 GLN A C   1 O43570 UNP 110 Q 
ATOM 848  C CB  . GLN A 1 110 ? -1.533  19.361  9.858   1.0 95.39 ? 110 GLN A CB  1 O43570 UNP 110 Q 
ATOM 849  O O   . GLN A 1 110 ? -2.698  21.838  8.133   1.0 95.39 ? 110 GLN A O   1 O43570 UNP 110 Q 
ATOM 850  C CG  . GLN A 1 110 ? -0.773  20.616  10.320  1.0 95.39 ? 110 GLN A CG  1 O43570 UNP 110 Q 
ATOM 851  C CD  . GLN A 1 110 ? 0.520   20.300  11.060  1.0 95.39 ? 110 GLN A CD  1 O43570 UNP 110 Q 
ATOM 852  N NE2 . GLN A 1 110 ? 1.263   21.305  11.467  1.0 95.39 ? 110 GLN A NE2 1 O43570 UNP 110 Q 
ATOM 853  O OE1 . GLN A 1 110 ? 0.883   19.165  11.311  1.0 95.39 ? 110 GLN A OE1 1 O43570 UNP 110 Q 
ATOM 854  N N   . SER A 1 111 ? -2.510  20.035  6.804   1.0 97.32 ? 111 SER A N   1 O43570 UNP 111 S 
ATOM 855  C CA  . SER A 1 111 ? -2.437  20.736  5.519   1.0 97.32 ? 111 SER A CA  1 O43570 UNP 111 S 
ATOM 856  C C   . SER A 1 111 ? -3.524  20.213  4.592   1.0 97.32 ? 111 SER A C   1 O43570 UNP 111 S 
ATOM 857  C CB  . SER A 1 111 ? -1.076  20.528  4.845   1.0 97.32 ? 111 SER A CB  1 O43570 UNP 111 S 
ATOM 858  O O   . SER A 1 111 ? -4.025  19.100  4.780   1.0 97.32 ? 111 SER A O   1 O43570 UNP 111 S 
ATOM 859  O OG  . SER A 1 111 ? -0.015  20.973  5.667   1.0 97.32 ? 111 SER A OG  1 O43570 UNP 111 S 
ATOM 860  N N   . ARG A 1 112 ? -3.841  20.974  3.547   1.0 98.11 ? 112 ARG A N   1 O43570 UNP 112 R 
ATOM 861  C CA  . ARG A 1 112 ? -4.635  20.478  2.428   1.0 98.11 ? 112 ARG A CA  1 O43570 UNP 112 R 
ATOM 862  C C   . ARG A 1 112 ? -3.829  19.462  1.621   1.0 98.11 ? 112 ARG A C   1 O43570 UNP 112 R 
ATOM 863  C CB  . ARG A 1 112 ? -5.085  21.667  1.574   1.0 98.11 ? 112 ARG A CB  1 O43570 UNP 112 R 
ATOM 864  O O   . ARG A 1 112 ? -2.742  19.762  1.122   1.0 98.11 ? 112 ARG A O   1 O43570 UNP 112 R 
ATOM 865  C CG  . ARG A 1 112 ? -5.874  21.203  0.345   1.0 98.11 ? 112 ARG A CG  1 O43570 UNP 112 R 
ATOM 866  C CD  . ARG A 1 112 ? -6.451  22.397  -0.412  1.0 98.11 ? 112 ARG A CD  1 O43570 UNP 112 R 
ATOM 867  N NE  . ARG A 1 112 ? -7.671  22.891  0.247   1.0 98.11 ? 112 ARG A NE  1 O43570 UNP 112 R 
ATOM 868  N NH1 . ARG A 1 112 ? -7.991  24.750  -1.045  1.0 98.11 ? 112 ARG A NH1 1 O43570 UNP 112 R 
ATOM 869  N NH2 . ARG A 1 112 ? -9.554  24.123  0.436   1.0 98.11 ? 112 ARG A NH2 1 O43570 UNP 112 R 
ATOM 870  C CZ  . ARG A 1 112 ? -8.394  23.926  -0.118  1.0 98.11 ? 112 ARG A CZ  1 O43570 UNP 112 R 
ATOM 871  N N   . TYR A 1 113 ? -4.407  18.276  1.438   1.0 98.80 ? 113 TYR A N   1 O43570 UNP 113 Y 
ATOM 872  C CA  . TYR A 1 113 ? -3.858  17.241  0.564   1.0 98.80 ? 113 TYR A CA  1 O43570 UNP 113 Y 
ATOM 873  C C   . TYR A 1 113 ? -4.737  17.089  -0.675  1.0 98.80 ? 113 TYR A C   1 O43570 UNP 113 Y 
ATOM 874  C CB  . TYR A 1 113 ? -3.674  15.928  1.330   1.0 98.80 ? 113 TYR A CB  1 O43570 UNP 113 Y 
ATOM 875  O O   . TYR A 1 113 ? -5.841  16.553  -0.593  1.0 98.80 ? 113 TYR A O   1 O43570 UNP 113 Y 
ATOM 876  C CG  . TYR A 1 113 ? -2.471  15.920  2.247   1.0 98.80 ? 113 TYR A CG  1 O43570 UNP 113 Y 
ATOM 877  C CD1 . TYR A 1 113 ? -1.260  15.324  1.841   1.0 98.80 ? 113 TYR A CD1 1 O43570 UNP 113 Y 
ATOM 878  C CD2 . TYR A 1 113 ? -2.570  16.511  3.517   1.0 98.80 ? 113 TYR A CD2 1 O43570 UNP 113 Y 
ATOM 879  C CE1 . TYR A 1 113 ? -0.161  15.298  2.722   1.0 98.80 ? 113 TYR A CE1 1 O43570 UNP 113 Y 
ATOM 880  C CE2 . TYR A 1 113 ? -1.469  16.513  4.389   1.0 98.80 ? 113 TYR A CE2 1 O43570 UNP 113 Y 
ATOM 881  O OH  . TYR A 1 113 ? 0.785   15.866  4.858   1.0 98.80 ? 113 TYR A OH  1 O43570 UNP 113 Y 
ATOM 882  C CZ  . TYR A 1 113 ? -0.265  15.893  3.997   1.0 98.80 ? 113 TYR A CZ  1 O43570 UNP 113 Y 
ATOM 883  N N   . SER A 1 114 ? -4.246  17.566  -1.817  1.0 98.81 ? 114 SER A N   1 O43570 UNP 114 S 
ATOM 884  C CA  . SER A 1 114 ? -4.955  17.537  -3.100  1.0 98.81 ? 114 SER A CA  1 O43570 UNP 114 S 
ATOM 885  C C   . SER A 1 114 ? -4.711  16.222  -3.836  1.0 98.81 ? 114 SER A C   1 O43570 UNP 114 S 
ATOM 886  C CB  . SER A 1 114 ? -4.555  18.732  -3.964  1.0 98.81 ? 114 SER A CB  1 O43570 UNP 114 S 
ATOM 887  O O   . SER A 1 114 ? -3.603  15.687  -3.811  1.0 98.81 ? 114 SER A O   1 O43570 UNP 114 S 
ATOM 888  O OG  . SER A 1 114 ? -4.940  19.935  -3.321  1.0 98.81 ? 114 SER A OG  1 O43570 UNP 114 S 
ATOM 889  N N   . ALA A 1 115 ? -5.742  15.679  -4.474  1.0 98.87 ? 115 ALA A N   1 O43570 UNP 115 A 
ATOM 890  C CA  . ALA A 1 115 ? -5.691  14.408  -5.177  1.0 98.87 ? 115 ALA A CA  1 O43570 UNP 115 A 
ATOM 891  C C   . ALA A 1 115 ? -4.789  14.493  -6.414  1.0 98.87 ? 115 ALA A C   1 O43570 UNP 115 A 
ATOM 892  C CB  . ALA A 1 115 ? -7.115  13.973  -5.540  1.0 98.87 ? 115 ALA A CB  1 O43570 UNP 115 A 
ATOM 893  O O   . ALA A 1 115 ? -4.629  15.544  -7.036  1.0 98.87 ? 115 ALA A O   1 O43570 UNP 115 A 
ATOM 894  N N   . THR A 1 116 ? -4.195  13.360  -6.780  1.0 98.76 ? 116 THR A N   1 O43570 UNP 116 T 
ATOM 895  C CA  . THR A 1 116 ? -3.416  13.231  -8.020  1.0 98.76 ? 116 THR A CA  1 O43570 UNP 116 T 
ATOM 896  C C   . THR A 1 116 ? -3.806  11.999  -8.824  1.0 98.76 ? 116 THR A C   1 O43570 UNP 116 T 
ATOM 897  C CB  . THR A 1 116 ? -1.906  13.279  -7.725  1.0 98.76 ? 116 THR A CB  1 O43570 UNP 116 T 
ATOM 898  O O   . THR A 1 116 ? -3.888  12.070  -10.051 1.0 98.76 ? 116 THR A O   1 O43570 UNP 116 T 
ATOM 899  C CG2 . THR A 1 116 ? -1.416  12.288  -6.664  1.0 98.76 ? 116 THR A CG2 1 O43570 UNP 116 T 
ATOM 900  O OG1 . THR A 1 116 ? -1.162  13.042  -8.898  1.0 98.76 ? 116 THR A OG1 1 O43570 UNP 116 T 
ATOM 901  N N   . GLN A 1 117 ? -4.070  10.872  -8.164  1.0 98.79 ? 117 GLN A N   1 O43570 UNP 117 Q 
ATOM 902  C CA  . GLN A 1 117 ? -4.468  9.631   -8.820  1.0 98.79 ? 117 GLN A CA  1 O43570 UNP 117 Q 
ATOM 903  C C   . GLN A 1 117 ? -5.076  8.646   -7.823  1.0 98.79 ? 117 GLN A C   1 O43570 UNP 117 Q 
ATOM 904  C CB  . GLN A 1 117 ? -3.265  9.009   -9.564  1.0 98.79 ? 117 GLN A CB  1 O43570 UNP 117 Q 
ATOM 905  O O   . GLN A 1 117 ? -4.828  8.756   -6.622  1.0 98.79 ? 117 GLN A O   1 O43570 UNP 117 Q 
ATOM 906  C CG  . GLN A 1 117 ? -2.018  8.679   -8.714  1.0 98.79 ? 117 GLN A CG  1 O43570 UNP 117 Q 
ATOM 907  C CD  . GLN A 1 117 ? -1.997  7.266   -8.140  1.0 98.79 ? 117 GLN A CD  1 O43570 UNP 117 Q 
ATOM 908  N NE2 . GLN A 1 117 ? -0.847  6.747   -7.774  1.0 98.79 ? 117 GLN A NE2 1 O43570 UNP 117 Q 
ATOM 909  O OE1 . GLN A 1 117 ? -2.989  6.579   -8.035  1.0 98.79 ? 117 GLN A OE1 1 O43570 UNP 117 Q 
ATOM 910  N N   . LEU A 1 118 ? -5.821  7.670   -8.334  1.0 98.89 ? 118 LEU A N   1 O43570 UNP 118 L 
ATOM 911  C CA  . LEU A 1 118 ? -6.104  6.426   -7.625  1.0 98.89 ? 118 LEU A CA  1 O43570 UNP 118 L 
ATOM 912  C C   . LEU A 1 118 ? -5.614  5.210   -8.420  1.0 98.89 ? 118 LEU A C   1 O43570 UNP 118 L 
ATOM 913  C CB  . LEU A 1 118 ? -7.580  6.365   -7.198  1.0 98.89 ? 118 LEU A CB  1 O43570 UNP 118 L 
ATOM 914  O O   . LEU A 1 118 ? -5.502  5.279   -9.647  1.0 98.89 ? 118 LEU A O   1 O43570 UNP 118 L 
ATOM 915  C CG  . LEU A 1 118 ? -8.626  6.362   -8.332  1.0 98.89 ? 118 LEU A CG  1 O43570 UNP 118 L 
ATOM 916  C CD1 . LEU A 1 118 ? -8.797  4.999   -9.015  1.0 98.89 ? 118 LEU A CD1 1 O43570 UNP 118 L 
ATOM 917  C CD2 . LEU A 1 118 ? -10.001 6.728   -7.771  1.0 98.89 ? 118 LEU A CD2 1 O43570 UNP 118 L 
ATOM 918  N N   . HIS A 1 119 ? -5.314  4.111   -7.731  1.0 98.91 ? 119 HIS A N   1 O43570 UNP 119 H 
ATOM 919  C CA  . HIS A 1 119 ? -4.881  2.843   -8.329  1.0 98.91 ? 119 HIS A CA  1 O43570 UNP 119 H 
ATOM 920  C C   . HIS A 1 119 ? -5.208  1.652   -7.419  1.0 98.91 ? 119 HIS A C   1 O43570 UNP 119 H 
ATOM 921  C CB  . HIS A 1 119 ? -3.382  2.898   -8.663  1.0 98.91 ? 119 HIS A CB  1 O43570 UNP 119 H 
ATOM 922  O O   . HIS A 1 119 ? -5.586  1.849   -6.265  1.0 98.91 ? 119 HIS A O   1 O43570 UNP 119 H 
ATOM 923  C CG  . HIS A 1 119 ? -2.473  3.057   -7.472  1.0 98.91 ? 119 HIS A CG  1 O43570 UNP 119 H 
ATOM 924  C CD2 . HIS A 1 119 ? -1.596  2.138   -6.963  1.0 98.91 ? 119 HIS A CD2 1 O43570 UNP 119 H 
ATOM 925  N ND1 . HIS A 1 119 ? -2.347  4.197   -6.717  1.0 98.91 ? 119 HIS A ND1 1 O43570 UNP 119 H 
ATOM 926  C CE1 . HIS A 1 119 ? -1.420  3.976   -5.773  1.0 98.91 ? 119 HIS A CE1 1 O43570 UNP 119 H 
ATOM 927  N NE2 . HIS A 1 119 ? -0.884  2.766   -5.936  1.0 98.91 ? 119 HIS A NE2 1 O43570 UNP 119 H 
ATOM 928  N N   . LEU A 1 120 ? -5.098  0.429   -7.946  1.0 98.90 ? 120 LEU A N   1 O43570 UNP 120 L 
ATOM 929  C CA  . LEU A 1 120 ? -5.471  -0.796  -7.230  1.0 98.90 ? 120 LEU A CA  1 O43570 UNP 120 L 
ATOM 930  C C   . LEU A 1 120 ? -4.319  -1.805  -7.124  1.0 98.90 ? 120 LEU A C   1 O43570 UNP 120 L 
ATOM 931  C CB  . LEU A 1 120 ? -6.715  -1.458  -7.859  1.0 98.90 ? 120 LEU A CB  1 O43570 UNP 120 L 
ATOM 932  O O   . LEU A 1 120 ? -3.450  -1.869  -7.996  1.0 98.90 ? 120 LEU A O   1 O43570 UNP 120 L 
ATOM 933  C CG  . LEU A 1 120 ? -7.979  -0.578  -7.894  1.0 98.90 ? 120 LEU A CG  1 O43570 UNP 120 L 
ATOM 934  C CD1 . LEU A 1 120 ? -8.151  0.121   -9.249  1.0 98.90 ? 120 LEU A CD1 1 O43570 UNP 120 L 
ATOM 935  C CD2 . LEU A 1 120 ? -9.226  -1.433  -7.662  1.0 98.90 ? 120 LEU A CD2 1 O43570 UNP 120 L 
ATOM 936  N N   . HIS A 1 121 ? -4.384  -2.639  -6.095  1.0 98.92 ? 121 HIS A N   1 O43570 UNP 121 H 
ATOM 937  C CA  . HIS A 1 121 ? -3.540  -3.811  -5.869  1.0 98.92 ? 121 HIS A CA  1 O43570 UNP 121 H 
ATOM 938  C C   . HIS A 1 121 ? -4.436  -5.043  -5.710  1.0 98.92 ? 121 HIS A C   1 O43570 UNP 121 H 
ATOM 939  C CB  . HIS A 1 121 ? -2.689  -3.571  -4.620  1.0 98.92 ? 121 HIS A CB  1 O43570 UNP 121 H 
ATOM 940  O O   . HIS A 1 121 ? -5.496  -4.940  -5.093  1.0 98.92 ? 121 HIS A O   1 O43570 UNP 121 H 
ATOM 941  C CG  . HIS A 1 121 ? -1.777  -2.381  -4.765  1.0 98.92 ? 121 HIS A CG  1 O43570 UNP 121 H 
ATOM 942  C CD2 . HIS A 1 121 ? -2.048  -1.076  -4.453  1.0 98.92 ? 121 HIS A CD2 1 O43570 UNP 121 H 
ATOM 943  N ND1 . HIS A 1 121 ? -0.513  -2.410  -5.289  1.0 98.92 ? 121 HIS A ND1 1 O43570 UNP 121 H 
ATOM 944  C CE1 . HIS A 1 121 ? -0.021  -1.167  -5.286  1.0 98.92 ? 121 HIS A CE1 1 O43570 UNP 121 H 
ATOM 945  N NE2 . HIS A 1 121 ? -0.937  -0.311  -4.824  1.0 98.92 ? 121 HIS A NE2 1 O43570 UNP 121 H 
ATOM 946  N N   . TRP A 1 122 ? -4.061  -6.173  -6.306  1.0 98.85 ? 122 TRP A N   1 O43570 UNP 122 W 
ATOM 947  C CA  . TRP A 1 122 ? -4.848  -7.405  -6.297  1.0 98.85 ? 122 TRP A CA  1 O43570 UNP 122 W 
ATOM 948  C C   . TRP A 1 122 ? -3.972  -8.657  -6.425  1.0 98.85 ? 122 TRP A C   1 O43570 UNP 122 W 
ATOM 949  C CB  . TRP A 1 122 ? -5.897  -7.359  -7.418  1.0 98.85 ? 122 TRP A CB  1 O43570 UNP 122 W 
ATOM 950  O O   . TRP A 1 122 ? -2.781  -8.603  -6.756  1.0 98.85 ? 122 TRP A O   1 O43570 UNP 122 W 
ATOM 951  C CG  . TRP A 1 122 ? -5.345  -7.265  -8.807  1.0 98.85 ? 122 TRP A CG  1 O43570 UNP 122 W 
ATOM 952  C CD1 . TRP A 1 122 ? -5.006  -8.310  -9.594  1.0 98.85 ? 122 TRP A CD1 1 O43570 UNP 122 W 
ATOM 953  C CD2 . TRP A 1 122 ? -5.029  -6.067  -9.578  1.0 98.85 ? 122 TRP A CD2 1 O43570 UNP 122 W 
ATOM 954  C CE2 . TRP A 1 122 ? -4.529  -6.473  -10.848 1.0 98.85 ? 122 TRP A CE2 1 O43570 UNP 122 W 
ATOM 955  C CE3 . TRP A 1 122 ? -5.113  -4.677  -9.336  1.0 98.85 ? 122 TRP A CE3 1 O43570 UNP 122 W 
ATOM 956  N NE1 . TRP A 1 122 ? -4.530  -7.845  -10.802 1.0 98.85 ? 122 TRP A NE1 1 O43570 UNP 122 W 
ATOM 957  C CH2 . TRP A 1 122 ? -4.248  -4.180  -11.565 1.0 98.85 ? 122 TRP A CH2 1 O43570 UNP 122 W 
ATOM 958  C CZ2 . TRP A 1 122 ? -4.151  -5.555  -11.833 1.0 98.85 ? 122 TRP A CZ2 1 O43570 UNP 122 W 
ATOM 959  C CZ3 . TRP A 1 122 ? -4.723  -3.743  -10.317 1.0 98.85 ? 122 TRP A CZ3 1 O43570 UNP 122 W 
ATOM 960  N N   . GLY A 1 123 ? -4.587  -9.802  -6.130  1.0 98.53 ? 123 GLY A N   1 O43570 UNP 123 G 
ATOM 961  C CA  . GLY A 1 123 ? -3.949  -11.113 -6.149  1.0 98.53 ? 123 GLY A CA  1 O43570 UNP 123 G 
ATOM 962  C C   . GLY A 1 123 ? -3.995  -11.759 -7.528  1.0 98.53 ? 123 GLY A C   1 O43570 UNP 123 G 
ATOM 963  O O   . GLY A 1 123 ? -3.630  -11.157 -8.543  1.0 98.53 ? 123 GLY A O   1 O43570 UNP 123 G 
ATOM 964  N N   . ASN A 1 124 ? -4.413  -13.018 -7.556  1.0 98.49 ? 124 ASN A N   1 O43570 UNP 124 N 
ATOM 965  C CA  . ASN A 1 124 ? -4.646  -13.777 -8.777  1.0 98.49 ? 124 ASN A CA  1 O43570 UNP 124 N 
ATOM 966  C C   . ASN A 1 124 ? -5.795  -14.777 -8.557  1.0 98.49 ? 124 ASN A C   1 O43570 UNP 124 N 
ATOM 967  C CB  . ASN A 1 124 ? -3.336  -14.482 -9.177  1.0 98.49 ? 124 ASN A CB  1 O43570 UNP 124 N 
ATOM 968  O O   . ASN A 1 124 ? -6.051  -15.140 -7.412  1.0 98.49 ? 124 ASN A O   1 O43570 UNP 124 N 
ATOM 969  C CG  . ASN A 1 124 ? -2.985  -15.638 -8.265  1.0 98.49 ? 124 ASN A CG  1 O43570 UNP 124 N 
ATOM 970  N ND2 . ASN A 1 124 ? -2.220  -15.404 -7.226  1.0 98.49 ? 124 ASN A ND2 1 O43570 UNP 124 N 
ATOM 971  O OD1 . ASN A 1 124 ? -3.380  -16.767 -8.503  1.0 98.49 ? 124 ASN A OD1 1 O43570 UNP 124 N 
ATOM 972  N N   . PRO A 1 125 ? -6.408  -15.339 -9.614  1.0 98.26 ? 125 PRO A N   1 O43570 UNP 125 P 
ATOM 973  C CA  . PRO A 1 125 ? -7.592  -16.187 -9.447  1.0 98.26 ? 125 PRO A CA  1 O43570 UNP 125 P 
ATOM 974  C C   . PRO A 1 125 ? -7.372  -17.476 -8.636  1.0 98.26 ? 125 PRO A C   1 O43570 UNP 125 P 
ATOM 975  C CB  . PRO A 1 125 ? -8.058  -16.503 -10.872 1.0 98.26 ? 125 PRO A CB  1 O43570 UNP 125 P 
ATOM 976  O O   . PRO A 1 125 ? -8.337  -18.059 -8.145  1.0 98.26 ? 125 PRO A O   1 O43570 UNP 125 P 
ATOM 977  C CG  . PRO A 1 125 ? -7.535  -15.324 -11.690 1.0 98.26 ? 125 PRO A CG  1 O43570 UNP 125 P 
ATOM 978  C CD  . PRO A 1 125 ? -6.195  -15.037 -11.023 1.0 98.26 ? 125 PRO A CD  1 O43570 UNP 125 P 
ATOM 979  N N   . ASN A 1 126 ? -6.125  -17.953 -8.504  1.0 97.97 ? 126 ASN A N   1 O43570 UNP 126 N 
ATOM 980  C CA  . ASN A 1 126 ? -5.807  -19.134 -7.690  1.0 97.97 ? 126 ASN A CA  1 O43570 UNP 126 N 
ATOM 981  C C   . ASN A 1 126 ? -5.568  -18.794 -6.210  1.0 97.97 ? 126 ASN A C   1 O43570 UNP 126 N 
ATOM 982  C CB  . ASN A 1 126 ? -4.578  -19.860 -8.260  1.0 97.97 ? 126 ASN A CB  1 O43570 UNP 126 N 
ATOM 983  O O   . ASN A 1 126 ? -5.636  -19.689 -5.371  1.0 97.97 ? 126 ASN A O   1 O43570 UNP 126 N 
ATOM 984  C CG  . ASN A 1 126 ? -4.733  -20.295 -9.701  1.0 97.97 ? 126 ASN A CG  1 O43570 UNP 126 N 
ATOM 985  N ND2 . ASN A 1 126 ? -3.807  -19.922 -10.552 1.0 97.97 ? 126 ASN A ND2 1 O43570 UNP 126 N 
ATOM 986  O OD1 . ASN A 1 126 ? -5.657  -20.990 -10.088 1.0 97.97 ? 126 ASN A OD1 1 O43570 UNP 126 N 
ATOM 987  N N   . ASP A 1 127 ? -5.261  -17.533 -5.903  1.0 97.37 ? 127 ASP A N   1 O43570 UNP 127 D 
ATOM 988  C CA  . ASP A 1 127 ? -5.042  -17.004 -4.555  1.0 97.37 ? 127 ASP A CA  1 O43570 UNP 127 D 
ATOM 989  C C   . ASP A 1 127 ? -5.553  -15.545 -4.504  1.0 97.37 ? 127 ASP A C   1 O43570 UNP 127 D 
ATOM 990  C CB  . ASP A 1 127 ? -3.556  -17.140 -4.182  1.0 97.37 ? 127 ASP A CB  1 O43570 UNP 127 D 
ATOM 991  O O   . ASP A 1 127 ? -4.768  -14.599 -4.664  1.0 97.37 ? 127 ASP A O   1 O43570 UNP 127 D 
ATOM 992  C CG  . ASP A 1 127 ? -3.271  -16.829 -2.708  1.0 97.37 ? 127 ASP A CG  1 O43570 UNP 127 D 
ATOM 993  O OD1 . ASP A 1 127 ? -4.243  -16.649 -1.940  1.0 97.37 ? 127 ASP A OD1 1 O43570 UNP 127 D 
ATOM 994  O OD2 . ASP A 1 127 ? -2.069  -16.847 -2.360  1.0 97.37 ? 127 ASP A OD2 1 O43570 UNP 127 D 
ATOM 995  N N   . PRO A 1 128 ? -6.885  -15.347 -4.395  1.0 97.16 ? 128 PRO A N   1 O43570 UNP 128 P 
ATOM 996  C CA  . PRO A 1 128 ? -7.547  -14.050 -4.560  1.0 97.16 ? 128 PRO A CA  1 O43570 UNP 128 P 
ATOM 997  C C   . PRO A 1 128 ? -7.463  -13.202 -3.279  1.0 97.16 ? 128 PRO A C   1 O43570 UNP 128 P 
ATOM 998  C CB  . PRO A 1 128 ? -8.974  -14.396 -5.001  1.0 97.16 ? 128 PRO A CB  1 O43570 UNP 128 P 
ATOM 999  O O   . PRO A 1 128 ? -8.470  -12.725 -2.756  1.0 97.16 ? 128 PRO A O   1 O43570 UNP 128 P 
ATOM 1000 C CG  . PRO A 1 128 ? -9.248  -15.687 -4.235  1.0 97.16 ? 128 PRO A CG  1 O43570 UNP 128 P 
ATOM 1001 C CD  . PRO A 1 128 ? -7.896  -16.396 -4.284  1.0 97.16 ? 128 PRO A CD  1 O43570 UNP 128 P 
ATOM 1002 N N   . HIS A 1 129 ? -6.248  -13.055 -2.747  1.0 98.45 ? 129 HIS A N   1 O43570 UNP 129 H 
ATOM 1003 C CA  . HIS A 1 129 ? -5.915  -12.359 -1.504  1.0 98.45 ? 129 HIS A CA  1 O43570 UNP 129 H 
ATOM 1004 C C   . HIS A 1 129 ? -4.725  -11.414 -1.736  1.0 98.45 ? 129 HIS A C   1 O43570 UNP 129 H 
ATOM 1005 C CB  . HIS A 1 129 ? -5.606  -13.399 -0.414  1.0 98.45 ? 129 HIS A CB  1 O43570 UNP 129 H 
ATOM 1006 O O   . HIS A 1 129 ? -3.594  -11.730 -1.373  1.0 98.45 ? 129 HIS A O   1 O43570 UNP 129 H 
ATOM 1007 C CG  . HIS A 1 129 ? -6.787  -14.232 0.004   1.0 98.45 ? 129 HIS A CG  1 O43570 UNP 129 H 
ATOM 1008 C CD2 . HIS A 1 129 ? -7.045  -15.525 -0.364  1.0 98.45 ? 129 HIS A CD2 1 O43570 UNP 129 H 
ATOM 1009 N ND1 . HIS A 1 129 ? -7.790  -13.840 0.859   1.0 98.45 ? 129 HIS A ND1 1 O43570 UNP 129 H 
ATOM 1010 C CE1 . HIS A 1 129 ? -8.642  -14.869 0.988   1.0 98.45 ? 129 HIS A CE1 1 O43570 UNP 129 H 
ATOM 1011 N NE2 . HIS A 1 129 ? -8.231  -15.925 0.269   1.0 98.45 ? 129 HIS A NE2 1 O43570 UNP 129 H 
ATOM 1012 N N   . GLY A 1 130 ? -4.957  -10.266 -2.382  1.0 98.56 ? 130 GLY A N   1 O43570 UNP 130 G 
ATOM 1013 C CA  . GLY A 1 130 ? -3.887  -9.345  -2.783  1.0 98.56 ? 130 GLY A CA  1 O43570 UNP 130 G 
ATOM 1014 C C   . GLY A 1 130 ? -4.057  -7.895  -2.349  1.0 98.56 ? 130 GLY A C   1 O43570 UNP 130 G 
ATOM 1015 O O   . GLY A 1 130 ? -3.654  -6.994  -3.086  1.0 98.56 ? 130 GLY A O   1 O43570 UNP 130 G 
ATOM 1016 N N   . SER A 1 131 ? -4.641  -7.642  -1.175  1.0 98.88 ? 131 SER A N   1 O43570 UNP 131 S 
ATOM 1017 C CA  . SER A 1 131 ? -4.454  -6.349  -0.503  1.0 98.88 ? 131 SER A CA  1 O43570 UNP 131 S 
ATOM 1018 C C   . SER A 1 131 ? -2.989  -6.133  -0.113  1.0 98.88 ? 131 SER A C   1 O43570 UNP 131 S 
ATOM 1019 C CB  . SER A 1 131 ? -5.367  -6.216  0.715   1.0 98.88 ? 131 SER A CB  1 O43570 UNP 131 S 
ATOM 1020 O O   . SER A 1 131 ? -2.238  -7.091  0.041   1.0 98.88 ? 131 SER A O   1 O43570 UNP 131 S 
ATOM 1021 O OG  . SER A 1 131 ? -4.984  -7.075  1.776   1.0 98.88 ? 131 SER A OG  1 O43570 UNP 131 S 
ATOM 1022 N N   . GLU A 1 132 ? -2.565  -4.888  0.084   1.0 98.91 ? 132 GLU A N   1 O43570 UNP 132 E 
ATOM 1023 C CA  . GLU A 1 132 ? -1.207  -4.593  0.551   1.0 98.91 ? 132 GLU A CA  1 O43570 UNP 132 E 
ATOM 1024 C C   . GLU A 1 132 ? -1.151  -4.619  2.083   1.0 98.91 ? 132 GLU A C   1 O43570 UNP 132 E 
ATOM 1025 C CB  . GLU A 1 132 ? -0.739  -3.239  -0.008  1.0 98.91 ? 132 GLU A CB  1 O43570 UNP 132 E 
ATOM 1026 O O   . GLU A 1 132 ? -0.349  -5.336  2.683   1.0 98.91 ? 132 GLU A O   1 O43570 UNP 132 E 
ATOM 1027 C CG  . GLU A 1 132 ? -0.647  -3.205  -1.539  1.0 98.91 ? 132 GLU A CG  1 O43570 UNP 132 E 
ATOM 1028 C CD  . GLU A 1 132 ? 0.570   -2.402  -1.999  1.0 98.91 ? 132 GLU A CD  1 O43570 UNP 132 E 
ATOM 1029 O OE1 . GLU A 1 132 ? 1.605   -3.003  -2.377  1.0 98.91 ? 132 GLU A OE1 1 O43570 UNP 132 E 
ATOM 1030 O OE2 . GLU A 1 132 ? 0.512   -1.162  -1.914  1.0 98.91 ? 132 GLU A OE2 1 O43570 UNP 132 E 
ATOM 1031 N N   . HIS A 1 133 ? -2.032  -3.859  2.737   1.0 98.90 ? 133 HIS A N   1 O43570 UNP 133 H 
ATOM 1032 C CA  . HIS A 1 133 ? -2.229  -3.940  4.176   1.0 98.90 ? 133 HIS A CA  1 O43570 UNP 133 H 
ATOM 1033 C C   . HIS A 1 133 ? -2.959  -5.231  4.534   1.0 98.90 ? 133 HIS A C   1 O43570 UNP 133 H 
ATOM 1034 C CB  . HIS A 1 133 ? -2.990  -2.716  4.701   1.0 98.90 ? 133 HIS A CB  1 O43570 UNP 133 H 
ATOM 1035 O O   . HIS A 1 133 ? -3.839  -5.707  3.812   1.0 98.90 ? 133 HIS A O   1 O43570 UNP 133 H 
ATOM 1036 C CG  . HIS A 1 133 ? -2.216  -1.437  4.556   1.0 98.90 ? 133 HIS A CG  1 O43570 UNP 133 H 
ATOM 1037 C CD2 . HIS A 1 133 ? -1.346  -0.895  5.459   1.0 98.90 ? 133 HIS A CD2 1 O43570 UNP 133 H 
ATOM 1038 N ND1 . HIS A 1 133 ? -2.233  -0.613  3.461   1.0 98.90 ? 133 HIS A ND1 1 O43570 UNP 133 H 
ATOM 1039 C CE1 . HIS A 1 133 ? -1.389  0.400   3.682   1.0 98.90 ? 133 HIS A CE1 1 O43570 UNP 133 H 
ATOM 1040 N NE2 . HIS A 1 133 ? -0.823  0.280   4.898   1.0 98.90 ? 133 HIS A NE2 1 O43570 UNP 133 H 
ATOM 1041 N N   . THR A 1 134 ? -2.621  -5.762  5.702   1.0 98.88 ? 134 THR A N   1 O43570 UNP 134 T 
ATOM 1042 C CA  . THR A 1 134 ? -3.349  -6.873  6.320   1.0 98.88 ? 134 THR A CA  1 O43570 UNP 134 T 
ATOM 1043 C C   . THR A 1 134 ? -3.974  -6.413  7.625   1.0 98.88 ? 134 THR A C   1 O43570 UNP 134 T 
ATOM 1044 C CB  . THR A 1 134 ? -2.463  -8.108  6.520   1.0 98.88 ? 134 THR A CB  1 O43570 UNP 134 T 
ATOM 1045 O O   . THR A 1 134 ? -3.554  -5.412  8.209   1.0 98.88 ? 134 THR A O   1 O43570 UNP 134 T 
ATOM 1046 C CG2 . THR A 1 134 ? -1.958  -8.654  5.195   1.0 98.88 ? 134 THR A CG2 1 O43570 UNP 134 T 
ATOM 1047 O OG1 . THR A 1 134 ? -1.312  -7.812  7.252   1.0 98.88 ? 134 THR A OG1 1 O43570 UNP 134 T 
ATOM 1048 N N   . VAL A 1 135 ? -5.011  -7.116  8.072   1.0 98.64 ? 135 VAL A N   1 O43570 UNP 135 V 
ATOM 1049 C CA  . VAL A 1 135 ? -5.608  -6.902  9.393   1.0 98.64 ? 135 VAL A CA  1 O43570 UNP 135 V 
ATOM 1050 C C   . VAL A 1 135 ? -5.510  -8.204  10.165  1.0 98.64 ? 135 VAL A C   1 O43570 UNP 135 V 
ATOM 1051 C CB  . VAL A 1 135 ? -7.059  -6.392  9.302   1.0 98.64 ? 135 VAL A CB  1 O43570 UNP 135 V 
ATOM 1052 O O   . VAL A 1 135 ? -6.146  -9.192  9.803   1.0 98.64 ? 135 VAL A O   1 O43570 UNP 135 V 
ATOM 1053 C CG1 . VAL A 1 135 ? -7.666  -6.176  10.697  1.0 98.64 ? 135 VAL A CG1 1 O43570 UNP 135 V 
ATOM 1054 C CG2 . VAL A 1 135 ? -7.143  -5.054  8.554   1.0 98.64 ? 135 VAL A CG2 1 O43570 UNP 135 V 
ATOM 1055 N N   . SER A 1 136 ? -4.723  -8.207  11.241  1.0 97.99 ? 136 SER A N   1 O43570 UNP 136 S 
ATOM 1056 C CA  . SER A 1 136 ? -4.465  -9.404  12.055  1.0 97.99 ? 136 SER A CA  1 O43570 UNP 136 S 
ATOM 1057 C C   . SER A 1 136 ? -3.923  -10.573 11.213  1.0 97.99 ? 136 SER A C   1 O43570 UNP 136 S 
ATOM 1058 C CB  . SER A 1 136 ? -5.707  -9.771  12.881  1.0 97.99 ? 136 SER A CB  1 O43570 UNP 136 S 
ATOM 1059 O O   . SER A 1 136 ? -4.383  -11.713 11.318  1.0 97.99 ? 136 SER A O   1 O43570 UNP 136 S 
ATOM 1060 O OG  . SER A 1 136 ? -6.173  -8.636  13.594  1.0 97.99 ? 136 SER A OG  1 O43570 UNP 136 S 
ATOM 1061 N N   . GLY A 1 137 ? -2.974  -10.261 10.326  1.0 97.96 ? 137 GLY A N   1 O43570 UNP 137 G 
ATOM 1062 C CA  . GLY A 1 137 ? -2.305  -11.191 9.418   1.0 97.96 ? 137 GLY A CA  1 O43570 UNP 137 G 
ATOM 1063 C C   . GLY A 1 137 ? -3.153  -11.688 8.245   1.0 97.96 ? 137 GLY A C   1 O43570 UNP 137 G 
ATOM 1064 O O   . GLY A 1 137 ? -2.716  -12.588 7.533   1.0 97.96 ? 137 GLY A O   1 O43570 UNP 137 G 
ATOM 1065 N N   . GLN A 1 138 ? -4.358  -11.147 8.043   1.0 98.40 ? 138 GLN A N   1 O43570 UNP 138 Q 
ATOM 1066 C CA  . GLN A 1 138 ? -5.245  -11.538 6.946   1.0 98.40 ? 138 GLN A CA  1 O43570 UNP 138 Q 
ATOM 1067 C C   . GLN A 1 138 ? -5.226  -10.501 5.823   1.0 98.40 ? 138 GLN A C   1 O43570 UNP 138 Q 
ATOM 1068 C CB  . GLN A 1 138 ? -6.677  -11.769 7.452   1.0 98.40 ? 138 GLN A CB  1 O43570 UNP 138 Q 
ATOM 1069 O O   . GLN A 1 138 ? -5.463  -9.313  6.059   1.0 98.40 ? 138 GLN A O   1 O43570 UNP 138 Q 
ATOM 1070 C CG  . GLN A 1 138 ? -6.778  -12.800 8.586   1.0 98.40 ? 138 GLN A CG  1 O43570 UNP 138 Q 
ATOM 1071 C CD  . GLN A 1 138 ? -6.175  -14.151 8.218   1.0 98.40 ? 138 GLN A CD  1 O43570 UNP 138 Q 
ATOM 1072 N NE2 . GLN A 1 138 ? -5.224  -14.643 8.980   1.0 98.40 ? 138 GLN A NE2 1 O43570 UNP 138 Q 
ATOM 1073 O OE1 . GLN A 1 138 ? -6.541  -14.787 7.245   1.0 98.40 ? 138 GLN A OE1 1 O43570 UNP 138 Q 
ATOM 1074 N N   . HIS A 1 139 ? -4.976  -10.970 4.602   1.0 98.73 ? 139 HIS A N   1 O43570 UNP 139 H 
ATOM 1075 C CA  . HIS A 1 139 ? -5.163  -10.190 3.384   1.0 98.73 ? 139 HIS A CA  1 O43570 UNP 139 H 
ATOM 1076 C C   . HIS A 1 139 ? -6.644  -10.114 3.000   1.0 98.73 ? 139 HIS A C   1 O43570 UNP 139 H 
ATOM 1077 C CB  . HIS A 1 139 ? -4.330  -10.786 2.239   1.0 98.73 ? 139 HIS A CB  1 O43570 UNP 139 H 
ATOM 1078 O O   . HIS A 1 139 ? -7.404  -11.074 3.148   1.0 98.73 ? 139 HIS A O   1 O43570 UNP 139 H 
ATOM 1079 C CG  . HIS A 1 139 ? -2.883  -10.376 2.270   1.0 98.73 ? 139 HIS A CG  1 O43570 UNP 139 H 
ATOM 1080 C CD2 . HIS A 1 139 ? -1.829  -11.077 2.791   1.0 98.73 ? 139 HIS A CD2 1 O43570 UNP 139 H 
ATOM 1081 N ND1 . HIS A 1 139 ? -2.366  -9.212  1.758   1.0 98.73 ? 139 HIS A ND1 1 O43570 UNP 139 H 
ATOM 1082 C CE1 . HIS A 1 139 ? -1.042  -9.207  1.960   1.0 98.73 ? 139 HIS A CE1 1 O43570 UNP 139 H 
ATOM 1083 N NE2 . HIS A 1 139 ? -0.663  -10.322 2.604   1.0 98.73 ? 139 HIS A NE2 1 O43570 UNP 139 H 
ATOM 1084 N N   . PHE A 1 140 ? -7.020  -8.969  2.445   1.0 98.76 ? 140 PHE A N   1 O43570 UNP 140 F 
ATOM 1085 C CA  . PHE A 1 140 ? -8.260  -8.763  1.706   1.0 98.76 ? 140 PHE A CA  1 O43570 UNP 140 F 
ATOM 1086 C C   . PHE A 1 140 ? -8.033  -9.098  0.224   1.0 98.76 ? 140 PHE A C   1 O43570 UNP 140 F 
ATOM 1087 C CB  . PHE A 1 140 ? -8.752  -7.330  1.954   1.0 98.76 ? 140 PHE A CB  1 O43570 UNP 140 F 
ATOM 1088 O O   . PHE A 1 140 ? -6.898  -9.314  -0.205  1.0 98.76 ? 140 PHE A O   1 O43570 UNP 140 F 
ATOM 1089 C CG  . PHE A 1 140 ? -9.297  -7.122  3.349   1.0 98.76 ? 140 PHE A CG  1 O43570 UNP 140 F 
ATOM 1090 C CD1 . PHE A 1 140 ? -10.686 -7.087  3.560   1.0 98.76 ? 140 PHE A CD1 1 O43570 UNP 140 F 
ATOM 1091 C CD2 . PHE A 1 140 ? -8.421  -6.994  4.443   1.0 98.76 ? 140 PHE A CD2 1 O43570 UNP 140 F 
ATOM 1092 C CE1 . PHE A 1 140 ? -11.200 -6.936  4.859   1.0 98.76 ? 140 PHE A CE1 1 O43570 UNP 140 F 
ATOM 1093 C CE2 . PHE A 1 140 ? -8.936  -6.854  5.741   1.0 98.76 ? 140 PHE A CE2 1 O43570 UNP 140 F 
ATOM 1094 C CZ  . PHE A 1 140 ? -10.324 -6.808  5.950   1.0 98.76 ? 140 PHE A CZ  1 O43570 UNP 140 F 
ATOM 1095 N N   . ALA A 1 141 ? -9.104  -9.172  -0.567  1.0 98.77 ? 141 ALA A N   1 O43570 UNP 141 A 
ATOM 1096 C CA  . ALA A 1 141 ? -9.011  -9.597  -1.963  1.0 98.77 ? 141 ALA A CA  1 O43570 UNP 141 A 
ATOM 1097 C C   . ALA A 1 141 ? -8.207  -8.611  -2.823  1.0 98.77 ? 141 ALA A C   1 O43570 UNP 141 A 
ATOM 1098 C CB  . ALA A 1 141 ? -10.424 -9.820  -2.514  1.0 98.77 ? 141 ALA A CB  1 O43570 UNP 141 A 
ATOM 1099 O O   . ALA A 1 141 ? -7.367  -9.011  -3.631  1.0 98.77 ? 141 ALA A O   1 O43570 UNP 141 A 
ATOM 1100 N N   . ALA A 1 142 ? -8.429  -7.318  -2.600  1.0 98.91 ? 142 ALA A N   1 O43570 UNP 142 A 
ATOM 1101 C CA  . ALA A 1 142 ? -7.729  -6.230  -3.265  1.0 98.91 ? 142 ALA A CA  1 O43570 UNP 142 A 
ATOM 1102 C C   . ALA A 1 142 ? -7.630  -5.005  -2.341  1.0 98.91 ? 142 ALA A C   1 O43570 UNP 142 A 
ATOM 1103 C CB  . ALA A 1 142 ? -8.469  -5.935  -4.584  1.0 98.91 ? 142 ALA A CB  1 O43570 UNP 142 A 
ATOM 1104 O O   . ALA A 1 142 ? -8.204  -4.971  -1.248  1.0 98.91 ? 142 ALA A O   1 O43570 UNP 142 A 
ATOM 1105 N N   . GLU A 1 143 ? -6.914  -3.978  -2.784  1.0 98.94 ? 143 GLU A N   1 O43570 UNP 143 E 
ATOM 1106 C CA  . GLU A 1 143 ? -6.820  -2.696  -2.088  1.0 98.94 ? 143 GLU A CA  1 O43570 UNP 143 E 
ATOM 1107 C C   . GLU A 1 143 ? -6.810  -1.532  -3.081  1.0 98.94 ? 143 GLU A C   1 O43570 UNP 143 E 
ATOM 1108 C CB  . GLU A 1 143 ? -5.584  -2.704  -1.183  1.0 98.94 ? 143 GLU A CB  1 O43570 UNP 143 E 
ATOM 1109 O O   . GLU A 1 143 ? -6.066  -1.541  -4.060  1.0 98.94 ? 143 GLU A O   1 O43570 UNP 143 E 
ATOM 1110 C CG  . GLU A 1 143 ? -5.551  -1.527  -0.199  1.0 98.94 ? 143 GLU A CG  1 O43570 UNP 143 E 
ATOM 1111 C CD  . GLU A 1 143 ? -4.421  -1.685  0.825   1.0 98.94 ? 143 GLU A CD  1 O43570 UNP 143 E 
ATOM 1112 O OE1 . GLU A 1 143 ? -3.824  -0.665  1.237   1.0 98.94 ? 143 GLU A OE1 1 O43570 UNP 143 E 
ATOM 1113 O OE2 . GLU A 1 143 ? -4.121  -2.825  1.226   1.0 98.94 ? 143 GLU A OE2 1 O43570 UNP 143 E 
ATOM 1114 N N   . LEU A 1 144 ? -7.647  -0.525  -2.833  1.0 98.93 ? 144 LEU A N   1 O43570 UNP 144 L 
ATOM 1115 C CA  . LEU A 1 144 ? -7.671  0.737   -3.574  1.0 98.93 ? 144 LEU A CA  1 O43570 UNP 144 L 
ATOM 1116 C C   . LEU A 1 144 ? -6.871  1.789   -2.807  1.0 98.93 ? 144 LEU A C   1 O43570 UNP 144 L 
ATOM 1117 C CB  . LEU A 1 144 ? -9.136  1.162   -3.796  1.0 98.93 ? 144 LEU A CB  1 O43570 UNP 144 L 
ATOM 1118 O O   . LEU A 1 144 ? -7.132  2.025   -1.628  1.0 98.93 ? 144 LEU A O   1 O43570 UNP 144 L 
ATOM 1119 C CG  . LEU A 1 144 ? -9.357  2.635   -4.199  1.0 98.93 ? 144 LEU A CG  1 O43570 UNP 144 L 
ATOM 1120 C CD1 . LEU A 1 144 ? -8.913  2.893   -5.636  1.0 98.93 ? 144 LEU A CD1 1 O43570 UNP 144 L 
ATOM 1121 C CD2 . LEU A 1 144 ? -10.834 3.005   -4.103  1.0 98.93 ? 144 LEU A CD2 1 O43570 UNP 144 L 
ATOM 1122 N N   . HIS A 1 145 ? -5.970  2.486   -3.495  1.0 98.94 ? 145 HIS A N   1 O43570 UNP 145 H 
ATOM 1123 C CA  . HIS A 1 145 ? -5.245  3.644   -2.973  1.0 98.94 ? 145 HIS A CA  1 O43570 UNP 145 H 
ATOM 1124 C C   . HIS A 1 145 ? -5.669  4.920   -3.687  1.0 98.94 ? 145 HIS A C   1 O43570 UNP 145 H 
ATOM 1125 C CB  . HIS A 1 145 ? -3.740  3.436   -3.146  1.0 98.94 ? 145 HIS A CB  1 O43570 UNP 145 H 
ATOM 1126 O O   . HIS A 1 145 ? -5.519  5.024   -4.902  1.0 98.94 ? 145 HIS A O   1 O43570 UNP 145 H 
ATOM 1127 C CG  . HIS A 1 145 ? -3.125  2.406   -2.245  1.0 98.94 ? 145 HIS A CG  1 O43570 UNP 145 H 
ATOM 1128 C CD2 . HIS A 1 145 ? -3.743  1.674   -1.275  1.0 98.94 ? 145 HIS A CD2 1 O43570 UNP 145 H 
ATOM 1129 N ND1 . HIS A 1 145 ? -1.783  2.055   -2.292  1.0 98.94 ? 145 HIS A ND1 1 O43570 UNP 145 H 
ATOM 1130 C CE1 . HIS A 1 145 ? -1.641  1.049   -1.419  1.0 98.94 ? 145 HIS A CE1 1 O43570 UNP 145 H 
ATOM 1131 N NE2 . HIS A 1 145 ? -2.791  0.828   -0.770  1.0 98.94 ? 145 HIS A NE2 1 O43570 UNP 145 H 
ATOM 1132 N N   . ILE A 1 146 ? -6.122  5.924   -2.932  1.0 98.92 ? 146 ILE A N   1 O43570 UNP 146 I 
ATOM 1133 C CA  . ILE A 1 146 ? -6.369  7.286   -3.429  1.0 98.92 ? 146 ILE A CA  1 O43570 UNP 146 I 
ATOM 1134 C C   . ILE A 1 146 ? -5.240  8.192   -2.935  1.0 98.92 ? 146 ILE A C   1 O43570 UNP 146 I 
ATOM 1135 C CB  . ILE A 1 146 ? -7.761  7.822   -3.032  1.0 98.92 ? 146 ILE A CB  1 O43570 UNP 146 I 
ATOM 1136 O O   . ILE A 1 146 ? -5.141  8.515   -1.746  1.0 98.92 ? 146 ILE A O   1 O43570 UNP 146 I 
ATOM 1137 C CG1 . ILE A 1 146 ? -8.878  6.785   -3.293  1.0 98.92 ? 146 ILE A CG1 1 O43570 UNP 146 I 
ATOM 1138 C CG2 . ILE A 1 146 ? -8.035  9.125   -3.810  1.0 98.92 ? 146 ILE A CG2 1 O43570 UNP 146 I 
ATOM 1139 C CD1 . ILE A 1 146 ? -10.274 7.279   -2.905  1.0 98.92 ? 146 ILE A CD1 1 O43570 UNP 146 I 
ATOM 1140 N N   . VAL A 1 147 ? -4.367  8.589   -3.857  1.0 98.85 ? 147 VAL A N   1 O43570 UNP 147 V 
ATOM 1141 C CA  . VAL A 1 147 ? -3.124  9.304   -3.569  1.0 98.85 ? 147 VAL A CA  1 O43570 UNP 147 V 
ATOM 1142 C C   . VAL A 1 147 ? -3.341  10.807  -3.653  1.0 98.85 ? 147 VAL A C   1 O43570 UNP 147 V 
ATOM 1143 C CB  . VAL A 1 147 ? -1.982  8.859   -4.500  1.0 98.85 ? 147 VAL A CB  1 O43570 UNP 147 V 
ATOM 1144 O O   . VAL A 1 147 ? -3.780  11.340  -4.677  1.0 98.85 ? 147 VAL A O   1 O43570 UNP 147 V 
ATOM 1145 C CG1 . VAL A 1 147 ? -0.643  9.490   -4.085  1.0 98.85 ? 147 VAL A CG1 1 O43570 UNP 147 V 
ATOM 1146 C CG2 . VAL A 1 147 ? -1.813  7.334   -4.490  1.0 98.85 ? 147 VAL A CG2 1 O43570 UNP 147 V 
ATOM 1147 N N   . HIS A 1 148 ? -2.956  11.488  -2.580  1.0 98.90 ? 148 HIS A N   1 O43570 UNP 148 H 
ATOM 1148 C CA  . HIS A 1 148 ? -2.975  12.934  -2.453  1.0 98.90 ? 148 HIS A CA  1 O43570 UNP 148 H 
ATOM 1149 C C   . HIS A 1 148 ? -1.580  13.460  -2.113  1.0 98.90 ? 148 HIS A C   1 O43570 UNP 148 H 
ATOM 1150 C CB  . HIS A 1 148 ? -3.983  13.357  -1.378  1.0 98.90 ? 148 HIS A CB  1 O43570 UNP 148 H 
ATOM 1151 O O   . HIS A 1 148 ? -0.756  12.749  -1.533  1.0 98.90 ? 148 HIS A O   1 O43570 UNP 148 H 
ATOM 1152 C CG  . HIS A 1 148 ? -5.375  12.820  -1.557  1.0 98.90 ? 148 HIS A CG  1 O43570 UNP 148 H 
ATOM 1153 C CD2 . HIS A 1 148 ? -6.483  13.542  -1.905  1.0 98.90 ? 148 HIS A CD2 1 O43570 UNP 148 H 
ATOM 1154 N ND1 . HIS A 1 148 ? -5.782  11.522  -1.349  1.0 98.90 ? 148 HIS A ND1 1 O43570 UNP 148 H 
ATOM 1155 C CE1 . HIS A 1 148 ? -7.099  11.464  -1.583  1.0 98.90 ? 148 HIS A CE1 1 O43570 UNP 148 H 
ATOM 1156 N NE2 . HIS A 1 148 ? -7.573  12.672  -1.929  1.0 98.90 ? 148 HIS A NE2 1 O43570 UNP 148 H 
ATOM 1157 N N   . TYR A 1 149 ? -1.323  14.723  -2.435  1.0 98.81 ? 149 TYR A N   1 O43570 UNP 149 Y 
ATOM 1158 C CA  . TYR A 1 149 ? -0.088  15.422  -2.102  1.0 98.81 ? 149 TYR A CA  1 O43570 UNP 149 Y 
ATOM 1159 C C   . TYR A 1 149 ? -0.373  16.723  -1.359  1.0 98.81 ? 149 TYR A C   1 O43570 UNP 149 Y 
ATOM 1160 C CB  . TYR A 1 149 ? 0.740   15.670  -3.364  1.0 98.81 ? 149 TYR A CB  1 O43570 UNP 149 Y 
ATOM 1161 O O   . TYR A 1 149 ? -1.415  17.343  -1.561  1.0 98.81 ? 149 TYR A O   1 O43570 UNP 149 Y 
ATOM 1162 C CG  . TYR A 1 149 ? 0.213   16.771  -4.266  1.0 98.81 ? 149 TYR A CG  1 O43570 UNP 149 Y 
ATOM 1163 C CD1 . TYR A 1 149 ? -0.854  16.513  -5.148  1.0 98.81 ? 149 TYR A CD1 1 O43570 UNP 149 Y 
ATOM 1164 C CD2 . TYR A 1 149 ? 0.776   18.062  -4.204  1.0 98.81 ? 149 TYR A CD2 1 O43570 UNP 149 Y 
ATOM 1165 C CE1 . TYR A 1 149 ? -1.350  17.537  -5.976  1.0 98.81 ? 149 TYR A CE1 1 O43570 UNP 149 Y 
ATOM 1166 C CE2 . TYR A 1 149 ? 0.287   19.085  -5.037  1.0 98.81 ? 149 TYR A CE2 1 O43570 UNP 149 Y 
ATOM 1167 O OH  . TYR A 1 149 ? -1.217  19.798  -6.762  1.0 98.81 ? 149 TYR A OH  1 O43570 UNP 149 Y 
ATOM 1168 C CZ  . TYR A 1 149 ? -0.773  18.823  -5.929  1.0 98.81 ? 149 TYR A CZ  1 O43570 UNP 149 Y 
ATOM 1169 N N   . ASN A 1 150 ? 0.555   17.142  -0.502  1.0 98.62 ? 150 ASN A N   1 O43570 UNP 150 N 
ATOM 1170 C CA  . ASN A 1 150 ? 0.424   18.375  0.262   1.0 98.62 ? 150 ASN A CA  1 O43570 UNP 150 N 
ATOM 1171 C C   . ASN A 1 150 ? 0.564   19.596  -0.657  1.0 98.62 ? 150 ASN A C   1 O43570 UNP 150 N 
ATOM 1172 C CB  . ASN A 1 150 ? 1.446   18.345  1.399   1.0 98.62 ? 150 ASN A CB  1 O43570 UNP 150 N 
ATOM 1173 O O   . ASN A 1 150 ? 1.673   19.998  -1.015  1.0 98.62 ? 150 ASN A O   1 O43570 UNP 150 N 
ATOM 1174 C CG  . ASN A 1 150 ? 1.275   19.484  2.380   1.0 98.62 ? 150 ASN A CG  1 O43570 UNP 150 N 
ATOM 1175 N ND2 . ASN A 1 150 ? 1.680   19.264  3.607   1.0 98.62 ? 150 ASN A ND2 1 O43570 UNP 150 N 
ATOM 1176 O OD1 . ASN A 1 150 ? 0.779   20.553  2.062   1.0 98.62 ? 150 ASN A OD1 1 O43570 UNP 150 N 
ATOM 1177 N N   . SER A 1 151 ? -0.575  20.166  -1.043  1.0 98.36 ? 151 SER A N   1 O43570 UNP 151 S 
ATOM 1178 C CA  . SER A 1 151 ? -0.655  21.287  -1.982  1.0 98.36 ? 151 SER A CA  1 O43570 UNP 151 S 
ATOM 1179 C C   . SER A 1 151 ? -0.415  22.645  -1.327  1.0 98.36 ? 151 SER A C   1 O43570 UNP 151 S 
ATOM 1180 C CB  . SER A 1 151 ? -2.007  21.277  -2.693  1.0 98.36 ? 151 SER A CB  1 O43570 UNP 151 S 
ATOM 1181 O O   . SER A 1 151 ? -0.238  23.630  -2.038  1.0 98.36 ? 151 SER A O   1 O43570 UNP 151 S 
ATOM 1182 O OG  . SER A 1 151 ? -3.071  21.229  -1.754  1.0 98.36 ? 151 SER A OG  1 O43570 UNP 151 S 
ATOM 1183 N N   . ASP A 1 152 ? -0.402  22.711  0.007   1.0 98.07 ? 152 ASP A N   1 O43570 UNP 152 D 
ATOM 1184 C CA  . ASP A 1 152 ? -0.026  23.936  0.721   1.0 98.07 ? 152 ASP A CA  1 O43570 UNP 152 D 
ATOM 1185 C C   . ASP A 1 152 ? 1.494   24.149  0.685   1.0 98.07 ? 152 ASP A C   1 O43570 UNP 152 D 
ATOM 1186 C CB  . ASP A 1 152 ? -0.510  23.882  2.179   1.0 98.07 ? 152 ASP A CB  1 O43570 UNP 152 D 
ATOM 1187 O O   . ASP A 1 152 ? 1.967   25.284  0.668   1.0 98.07 ? 152 ASP A O   1 O43570 UNP 152 D 
ATOM 1188 C CG  . ASP A 1 152 ? -2.032  23.893  2.340   1.0 98.07 ? 152 ASP A CG  1 O43570 UNP 152 D 
ATOM 1189 O OD1 . ASP A 1 152 ? -2.744  24.349  1.416   1.0 98.07 ? 152 ASP A OD1 1 O43570 UNP 152 D 
ATOM 1190 O OD2 . ASP A 1 152 ? -2.487  23.422  3.408   1.0 98.07 ? 152 ASP A OD2 1 O43570 UNP 152 D 
ATOM 1191 N N   . LEU A 1 153 ? 2.266   23.054  0.665   1.0 98.09 ? 153 LEU A N   1 O43570 UNP 153 L 
ATOM 1192 C CA  . LEU A 1 153 ? 3.730   23.092  0.709   1.0 98.09 ? 153 LEU A CA  1 O43570 UNP 153 L 
ATOM 1193 C C   . LEU A 1 153 ? 4.396   22.856  -0.649  1.0 98.09 ? 153 LEU A C   1 O43570 UNP 153 L 
ATOM 1194 C CB  . LEU A 1 153 ? 4.231   22.059  1.732   1.0 98.09 ? 153 LEU A CB  1 O43570 UNP 153 L 
ATOM 1195 O O   . LEU A 1 153 ? 5.502   23.353  -0.879  1.0 98.09 ? 153 LEU A O   1 O43570 UNP 153 L 
ATOM 1196 C CG  . LEU A 1 153 ? 3.745   22.273  3.177   1.0 98.09 ? 153 LEU A CG  1 O43570 UNP 153 L 
ATOM 1197 C CD1 . LEU A 1 153 ? 4.431   21.250  4.084   1.0 98.09 ? 153 LEU A CD1 1 O43570 UNP 153 L 
ATOM 1198 C CD2 . LEU A 1 153 ? 4.066   23.672  3.712   1.0 98.09 ? 153 LEU A CD2 1 O43570 UNP 153 L 
ATOM 1199 N N   . TYR A 1 154 ? 3.768   22.082  -1.537  1.0 98.34 ? 154 TYR A N   1 O43570 UNP 154 Y 
ATOM 1200 C CA  . TYR A 1 154 ? 4.395   21.618  -2.773  1.0 98.34 ? 154 TYR A CA  1 O43570 UNP 154 Y 
ATOM 1201 C C   . TYR A 1 154 ? 3.516   21.888  -3.999  1.0 98.34 ? 154 TYR A C   1 O43570 UNP 154 Y 
ATOM 1202 C CB  . TYR A 1 154 ? 4.761   20.132  -2.641  1.0 98.34 ? 154 TYR A CB  1 O43570 UNP 154 Y 
ATOM 1203 O O   . TYR A 1 154 ? 2.299   21.725  -3.931  1.0 98.34 ? 154 TYR A O   1 O43570 UNP 154 Y 
ATOM 1204 C CG  . TYR A 1 154 ? 5.583   19.817  -1.402  1.0 98.34 ? 154 TYR A CG  1 O43570 UNP 154 Y 
ATOM 1205 C CD1 . TYR A 1 154 ? 6.780   20.518  -1.164  1.0 98.34 ? 154 TYR A CD1 1 O43570 UNP 154 Y 
ATOM 1206 C CD2 . TYR A 1 154 ? 5.094   18.919  -0.432  1.0 98.34 ? 154 TYR A CD2 1 O43570 UNP 154 Y 
ATOM 1207 C CE1 . TYR A 1 154 ? 7.462   20.358  0.052   1.0 98.34 ? 154 TYR A CE1 1 O43570 UNP 154 Y 
ATOM 1208 C CE2 . TYR A 1 154 ? 5.807   18.714  0.767   1.0 98.34 ? 154 TYR A CE2 1 O43570 UNP 154 Y 
ATOM 1209 O OH  . TYR A 1 154 ? 7.664   19.309  2.178   1.0 98.34 ? 154 TYR A OH  1 O43570 UNP 154 Y 
ATOM 1210 C CZ  . TYR A 1 154 ? 6.986   19.444  1.012   1.0 98.34 ? 154 TYR A CZ  1 O43570 UNP 154 Y 
ATOM 1211 N N   . PRO A 1 155 ? 4.116   22.268  -5.144  1.0 97.68 ? 155 PRO A N   1 O43570 UNP 155 P 
ATOM 1212 C CA  . PRO A 1 155 ? 3.360   22.638  -6.342  1.0 97.68 ? 155 PRO A CA  1 O43570 UNP 155 P 
ATOM 1213 C C   . PRO A 1 155 ? 2.657   21.445  -7.005  1.0 97.68 ? 155 PRO A C   1 O43570 UNP 155 P 
ATOM 1214 C CB  . PRO A 1 155 ? 4.396   23.273  -7.277  1.0 97.68 ? 155 PRO A CB  1 O43570 UNP 155 P 
ATOM 1215 O O   . PRO A 1 155 ? 1.603   21.607  -7.614  1.0 97.68 ? 155 PRO A O   1 O43570 UNP 155 P 
ATOM 1216 C CG  . PRO A 1 155 ? 5.714   22.614  -6.871  1.0 97.68 ? 155 PRO A CG  1 O43570 UNP 155 P 
ATOM 1217 C CD  . PRO A 1 155 ? 5.547   22.438  -5.365  1.0 97.68 ? 155 PRO A CD  1 O43570 UNP 155 P 
ATOM 1218 N N   . ASP A 1 156 ? 3.223   20.246  -6.880  1.0 98.19 ? 156 ASP A N   1 O43570 UNP 156 D 
ATOM 1219 C CA  . ASP A 1 156 ? 2.736   19.033  -7.529  1.0 98.19 ? 156 ASP A CA  1 O43570 UNP 156 D 
ATOM 1220 C C   . ASP A 1 156 ? 3.169   17.769  -6.765  1.0 98.19 ? 156 ASP A C   1 O43570 UNP 156 D 
ATOM 1221 C CB  . ASP A 1 156 ? 3.224   19.005  -8.991  1.0 98.19 ? 156 ASP A CB  1 O43570 UNP 156 D 
ATOM 1222 O O   . ASP A 1 156 ? 4.093   17.788  -5.941  1.0 98.19 ? 156 ASP A O   1 O43570 UNP 156 D 
ATOM 1223 C CG  . ASP A 1 156 ? 4.749   19.023  -9.097  1.0 98.19 ? 156 ASP A CG  1 O43570 UNP 156 D 
ATOM 1224 O OD1 . ASP A 1 156 ? 5.365   17.993  -8.741  1.0 98.19 ? 156 ASP A OD1 1 O43570 UNP 156 D 
ATOM 1225 O OD2 . ASP A 1 156 ? 5.329   20.054  -9.486  1.0 98.19 ? 156 ASP A OD2 1 O43570 UNP 156 D 
ATOM 1226 N N   . ALA A 1 157 ? 2.511   16.646  -7.067  1.0 97.88 ? 157 ALA A N   1 O43570 UNP 157 A 
ATOM 1227 C CA  . ALA A 1 157 ? 2.770   15.362  -6.421  1.0 97.88 ? 157 ALA A CA  1 O43570 UNP 157 A 
ATOM 1228 C C   . ALA A 1 157 ? 4.189   14.821  -6.671  1.0 97.88 ? 157 ALA A C   1 O43570 UNP 157 A 
ATOM 1229 C CB  . ALA A 1 157 ? 1.714   14.360  -6.901  1.0 97.88 ? 157 ALA A CB  1 O43570 UNP 157 A 
ATOM 1230 O O   . ALA A 1 157 ? 4.751   14.167  -5.793  1.0 97.88 ? 157 ALA A O   1 O43570 UNP 157 A 
ATOM 1231 N N   . SER A 1 158 ? 4.793   15.108  -7.831  1.0 97.14 ? 158 SER A N   1 O43570 UNP 158 S 
ATOM 1232 C CA  . SER A 1 158 ? 6.158   14.661  -8.146  1.0 97.14 ? 158 SER A CA  1 O43570 UNP 158 S 
ATOM 1233 C C   . SER A 1 158 ? 7.192   15.372  -7.277  1.0 97.14 ? 158 SER A C   1 O43570 UNP 158 S 
ATOM 1234 C CB  . SER A 1 158 ? 6.486   14.926  -9.618  1.0 97.14 ? 158 SER A CB  1 O43570 UNP 158 S 
ATOM 1235 O O   . SER A 1 158 ? 8.193   14.779  -6.881  1.0 97.14 ? 158 SER A O   1 O43570 UNP 158 S 
ATOM 1236 O OG  . SER A 1 158 ? 7.746   14.360  -9.930  1.0 97.14 ? 158 SER A OG  1 O43570 UNP 158 S 
ATOM 1237 N N   . THR A 1 159 ? 6.961   16.647  -6.981  1.0 97.56 ? 159 THR A N   1 O43570 UNP 159 T 
ATOM 1238 C CA  . THR A 1 159 ? 7.788   17.442  -6.082  1.0 97.56 ? 159 THR A CA  1 O43570 UNP 159 T 
ATOM 1239 C C   . THR A 1 159 ? 7.544   17.027  -4.638  1.0 97.56 ? 159 THR A C   1 O43570 UNP 159 T 
ATOM 1240 C CB  . THR A 1 159 ? 7.508   18.938  -6.283  1.0 97.56 ? 159 THR A CB  1 O43570 UNP 159 T 
ATOM 1241 O O   . THR A 1 159 ? 8.493   16.977  -3.859  1.0 97.56 ? 159 THR A O   1 O43570 UNP 159 T 
ATOM 1242 C CG2 . THR A 1 159 ? 8.405   19.815  -5.403  1.0 97.56 ? 159 THR A CG2 1 O43570 UNP 159 T 
ATOM 1243 O OG1 . THR A 1 159 ? 7.816   19.292  -7.607  1.0 97.56 ? 159 THR A OG1 1 O43570 UNP 159 T 
ATOM 1244 N N   . ALA A 1 160 ? 6.305   16.718  -4.268  1.0 98.05 ? 160 ALA A N   1 O43570 UNP 160 A 
ATOM 1245 C CA  . ALA A 1 160 ? 5.952   16.329  -2.910  1.0 98.05 ? 160 ALA A CA  1 O43570 UNP 160 A 
ATOM 1246 C C   . ALA A 1 160 ? 6.456   14.926  -2.528  1.0 98.05 ? 160 ALA A C   1 O43570 UNP 160 A 
ATOM 1247 C CB  . ALA A 1 160 ? 4.433   16.405  -2.800  1.0 98.05 ? 160 ALA A CB  1 O43570 UNP 160 A 
ATOM 1248 O O   . ALA A 1 160 ? 6.825   14.705  -1.377  1.0 98.05 ? 160 ALA A O   1 O43570 UNP 160 A 
ATOM 1249 N N   . SER A 1 161 ? 6.512   13.980  -3.474  1.0 95.90 ? 161 SER A N   1 O43570 UNP 161 S 
ATOM 1250 C CA  . SER A 1 161 ? 6.695   12.546  -3.188  1.0 95.90 ? 161 SER A CA  1 O43570 UNP 161 S 
ATOM 1251 C C   . SER A 1 161 ? 7.957   12.193  -2.400  1.0 95.90 ? 161 SER A C   1 O43570 UNP 161 S 
ATOM 1252 C CB  . SER A 1 161 ? 6.691   11.728  -4.483  1.0 95.90 ? 161 SER A CB  1 O43570 UNP 161 S 
ATOM 1253 O O   . SER A 1 161 ? 7.968   11.192  -1.687  1.0 95.90 ? 161 SER A O   1 O43570 UNP 161 S 
ATOM 1254 O OG  . SER A 1 161 ? 7.869   11.968  -5.229  1.0 95.90 ? 161 SER A OG  1 O43570 UNP 161 S 
ATOM 1255 N N   . ASN A 1 162 ? 9.007   13.012  -2.481  1.0 95.31 ? 162 ASN A N   1 O43570 UNP 162 N 
ATOM 1256 C CA  . ASN A 1 162 ? 10.267  12.809  -1.770  1.0 95.31 ? 162 ASN A CA  1 O43570 UNP 162 N 
ATOM 1257 C C   . ASN A 1 162 ? 10.507  13.800  -0.619  1.0 95.31 ? 162 ASN A C   1 O43570 UNP 162 N 
ATOM 1258 C CB  . ASN A 1 162 ? 11.415  12.756  -2.788  1.0 95.31 ? 162 ASN A CB  1 O43570 UNP 162 N 
ATOM 1259 O O   . ASN A 1 162 ? 11.635  13.900  -0.135  1.0 95.31 ? 162 ASN A O   1 O43570 UNP 162 N 
ATOM 1260 C CG  . ASN A 1 162 ? 11.779  14.084  -3.441  1.0 95.31 ? 162 ASN A CG  1 O43570 UNP 162 N 
ATOM 1261 N ND2 . ASN A 1 162 ? 12.779  14.055  -4.289  1.0 95.31 ? 162 ASN A ND2 1 O43570 UNP 162 N 
ATOM 1262 O OD1 . ASN A 1 162 ? 11.218  15.152  -3.232  1.0 95.31 ? 162 ASN A OD1 1 O43570 UNP 162 N 
ATOM 1263 N N   . LYS A 1 163 ? 9.475   14.535  -0.186  1.0 96.67 ? 163 LYS A N   1 O43570 UNP 163 K 
ATOM 1264 C CA  . LYS A 1 163 ? 9.573   15.571  0.848   1.0 96.67 ? 163 LYS A CA  1 O43570 UNP 163 K 
ATOM 1265 C C   . LYS A 1 163 ? 8.757   15.231  2.092   1.0 96.67 ? 163 LYS A C   1 O43570 UNP 163 K 
ATOM 1266 C CB  . LYS A 1 163 ? 9.191   16.940  0.269   1.0 96.67 ? 163 LYS A CB  1 O43570 UNP 163 K 
ATOM 1267 O O   . LYS A 1 163 ? 7.841   14.411  2.065   1.0 96.67 ? 163 LYS A O   1 O43570 UNP 163 K 
ATOM 1268 C CG  . LYS A 1 163 ? 10.135  17.346  -0.867  1.0 96.67 ? 163 LYS A CG  1 O43570 UNP 163 K 
ATOM 1269 C CD  . LYS A 1 163 ? 9.853   18.765  -1.367  1.0 96.67 ? 163 LYS A CD  1 O43570 UNP 163 K 
ATOM 1270 C CE  . LYS A 1 163 ? 10.840  19.207  -2.451  1.0 96.67 ? 163 LYS A CE  1 O43570 UNP 163 K 
ATOM 1271 N NZ  . LYS A 1 163 ? 10.823  18.269  -3.597  1.0 96.67 ? 163 LYS A NZ  1 O43570 UNP 163 K 
ATOM 1272 N N   . SER A 1 164 ? 9.141   15.857  3.203   1.0 94.09 ? 164 SER A N   1 O43570 UNP 164 S 
ATOM 1273 C CA  . SER A 1 164 ? 8.454   15.714  4.487   1.0 94.09 ? 164 SER A CA  1 O43570 UNP 164 S 
ATOM 1274 C C   . SER A 1 164 ? 6.985   16.093  4.346   1.0 94.09 ? 164 SER A C   1 O43570 UNP 164 S 
ATOM 1275 C CB  . SER A 1 164 ? 9.106   16.616  5.534   1.0 94.09 ? 164 SER A CB  1 O43570 UNP 164 S 
ATOM 1276 O O   . SER A 1 164 ? 6.679   17.105  3.734   1.0 94.09 ? 164 SER A O   1 O43570 UNP 164 S 
ATOM 1277 O OG  . SER A 1 164 ? 8.531   16.374  6.800   1.0 94.09 ? 164 SER A OG  1 O43570 UNP 164 S 
ATOM 1278 N N   . GLU A 1 165 ? 6.085   15.291  4.915   1.0 94.54 ? 165 GLU A N   1 O43570 UNP 165 E 
ATOM 1279 C CA  . GLU A 1 165 ? 4.635   15.525  4.802   1.0 94.54 ? 165 GLU A CA  1 O43570 UNP 165 E 
ATOM 1280 C C   . GLU A 1 165 ? 4.156   15.662  3.348   1.0 94.54 ? 165 GLU A C   1 O43570 UNP 165 E 
ATOM 1281 C CB  . GLU A 1 165 ? 4.203   16.712  5.677   1.0 94.54 ? 165 GLU A CB  1 O43570 UNP 165 E 
ATOM 1282 O O   . GLU A 1 165 ? 3.223   16.399  3.051   1.0 94.54 ? 165 GLU A O   1 O43570 UNP 165 E 
ATOM 1283 C CG  . GLU A 1 165 ? 4.773   16.620  7.093   1.0 94.54 ? 165 GLU A CG  1 O43570 UNP 165 E 
ATOM 1284 C CD  . GLU A 1 165 ? 3.915   17.442  8.043   1.0 94.54 ? 165 GLU A CD  1 O43570 UNP 165 E 
ATOM 1285 O OE1 . GLU A 1 165 ? 3.166   16.772  8.797   1.0 94.54 ? 165 GLU A OE1 1 O43570 UNP 165 E 
ATOM 1286 O OE2 . GLU A 1 165 ? 3.998   18.684  7.977   1.0 94.54 ? 165 GLU A OE2 1 O43570 UNP 165 E 
ATOM 1287 N N   . GLY A 1 166 ? 4.841   14.976  2.431   1.0 97.78 ? 166 GLY A N   1 O43570 UNP 166 G 
ATOM 1288 C CA  . GLY A 1 166 ? 4.620   15.104  1.001   1.0 97.78 ? 166 GLY A CA  1 O43570 UNP 166 G 
ATOM 1289 C C   . GLY A 1 166 ? 3.303   14.508  0.534   1.0 97.78 ? 166 GLY A C   1 O43570 UNP 166 G 
ATOM 1290 O O   . GLY A 1 166 ? 2.616   15.116  -0.283  1.0 97.78 ? 166 GLY A O   1 O43570 UNP 166 G 
ATOM 1291 N N   . LEU A 1 167 ? 2.944   13.329  1.043   1.0 98.75 ? 167 LEU A N   1 O43570 UNP 167 L 
ATOM 1292 C CA  . LEU A 1 167 ? 1.819   12.548  0.540   1.0 98.75 ? 167 LEU A CA  1 O43570 UNP 167 L 
ATOM 1293 C C   . LEU A 1 167 ? 0.863   12.134  1.660   1.0 98.75 ? 167 LEU A C   1 O43570 UNP 167 L 
ATOM 1294 C CB  . LEU A 1 167 ? 2.346   11.317  -0.221  1.0 98.75 ? 167 LEU A CB  1 O43570 UNP 167 L 
ATOM 1295 O O   . LEU A 1 167 ? 1.273   11.888  2.794   1.0 98.75 ? 167 LEU A O   1 O43570 UNP 167 L 
ATOM 1296 C CG  . LEU A 1 167 ? 3.265   11.611  -1.423  1.0 98.75 ? 167 LEU A CG  1 O43570 UNP 167 L 
ATOM 1297 C CD1 . LEU A 1 167 ? 3.747   10.286  -2.020  1.0 98.75 ? 167 LEU A CD1 1 O43570 UNP 167 L 
ATOM 1298 C CD2 . LEU A 1 167 ? 2.575   12.407  -2.532  1.0 98.75 ? 167 LEU A CD2 1 O43570 UNP 167 L 
ATOM 1299 N N   . ALA A 1 168 ? -0.409  11.986  1.306   1.0 98.83 ? 168 ALA A N   1 O43570 UNP 168 A 
ATOM 1300 C CA  . ALA A 1 168 ? -1.408  11.297  2.110   1.0 98.83 ? 168 ALA A CA  1 O43570 UNP 168 A 
ATOM 1301 C C   . ALA A 1 168 ? -2.146  10.301  1.215   1.0 98.83 ? 168 ALA A C   1 O43570 UNP 168 A 
ATOM 1302 C CB  . ALA A 1 168 ? -2.358  12.301  2.772   1.0 98.83 ? 168 ALA A CB  1 O43570 UNP 168 A 
ATOM 1303 O O   . ALA A 1 168 ? -2.559  10.647  0.107   1.0 98.83 ? 168 ALA A O   1 O43570 UNP 168 A 
ATOM 1304 N N   . VAL A 1 169 ? -2.292  9.063   1.678   1.0 98.87 ? 169 VAL A N   1 O43570 UNP 169 V 
ATOM 1305 C CA  . VAL A 1 169 ? -2.973  8.010   0.916   1.0 98.87 ? 169 VAL A CA  1 O43570 UNP 169 V 
ATOM 1306 C C   . VAL A 1 169 ? -4.145  7.493   1.732   1.0 98.87 ? 169 VAL A C   1 O43570 UNP 169 V 
ATOM 1307 C CB  . VAL A 1 169 ? -2.017  6.884   0.479   1.0 98.87 ? 169 VAL A CB  1 O43570 UNP 169 V 
ATOM 1308 O O   . VAL A 1 169 ? -3.988  7.146   2.905   1.0 98.87 ? 169 VAL A O   1 O43570 UNP 169 V 
ATOM 1309 C CG1 . VAL A 1 169 ? -2.766  5.819   -0.333  1.0 98.87 ? 169 VAL A CG1 1 O43570 UNP 169 V 
ATOM 1310 C CG2 . VAL A 1 169 ? -0.902  7.427   -0.429  1.0 98.87 ? 169 VAL A CG2 1 O43570 UNP 169 V 
ATOM 1311 N N   . LEU A 1 170 ? -5.316  7.459   1.097   1.0 98.92 ? 170 LEU A N   1 O43570 UNP 170 L 
ATOM 1312 C CA  . LEU A 1 170 ? -6.475  6.734   1.601   1.0 98.92 ? 170 LEU A CA  1 O43570 UNP 170 L 
ATOM 1313 C C   . LEU A 1 170 ? -6.435  5.317   1.037   1.0 98.92 ? 170 LEU A C   1 O43570 UNP 170 L 
ATOM 1314 C CB  . LEU A 1 170 ? -7.783  7.427   1.195   1.0 98.92 ? 170 LEU A CB  1 O43570 UNP 170 L 
ATOM 1315 O O   . LEU A 1 170 ? -6.365  5.158   -0.181  1.0 98.92 ? 170 LEU A O   1 O43570 UNP 170 L 
ATOM 1316 C CG  . LEU A 1 170 ? -7.915  8.901   1.592   1.0 98.92 ? 170 LEU A CG  1 O43570 UNP 170 L 
ATOM 1317 C CD1 . LEU A 1 170 ? -9.290  9.409   1.168   1.0 98.92 ? 170 LEU A CD1 1 O43570 UNP 170 L 
ATOM 1318 C CD2 . LEU A 1 170 ? -7.746  9.122   3.094   1.0 98.92 ? 170 LEU A CD2 1 O43570 UNP 170 L 
ATOM 1319 N N   . ALA A 1 171 ? -6.483  4.317   1.907   1.0 98.94 ? 171 ALA A N   1 O43570 UNP 171 A 
ATOM 1320 C CA  . ALA A 1 171 ? -6.519  2.912   1.539   1.0 98.94 ? 171 ALA A CA  1 O43570 UNP 171 A 
ATOM 1321 C C   . ALA A 1 171 ? -7.882  2.308   1.881   1.0 98.94 ? 171 ALA A C   1 O43570 UNP 171 A 
ATOM 1322 C CB  . ALA A 1 171 ? -5.373  2.176   2.227   1.0 98.94 ? 171 ALA A CB  1 O43570 UNP 171 A 
ATOM 1323 O O   . ALA A 1 171 ? -8.345  2.396   3.023   1.0 98.94 ? 171 ALA A O   1 O43570 UNP 171 A 
ATOM 1324 N N   . VAL A 1 172 ? -8.508  1.690   0.883   1.0 98.94 ? 172 VAL A N   1 O43570 UNP 172 V 
ATOM 1325 C CA  . VAL A 1 172 ? -9.768  0.958   1.012   1.0 98.94 ? 172 VAL A CA  1 O43570 UNP 172 V 
ATOM 1326 C C   . VAL A 1 172 ? -9.483  -0.517  0.767   1.0 98.94 ? 172 VAL A C   1 O43570 UNP 172 V 
ATOM 1327 C CB  . VAL A 1 172 ? -10.835 1.477   0.031   1.0 98.94 ? 172 VAL A CB  1 O43570 UNP 172 V 
ATOM 1328 O O   . VAL A 1 172 ? -9.079  -0.900  -0.331  1.0 98.94 ? 172 VAL A O   1 O43570 UNP 172 V 
ATOM 1329 C CG1 . VAL A 1 172 ? -12.147 0.712   0.213   1.0 98.94 ? 172 VAL A CG1 1 O43570 UNP 172 V 
ATOM 1330 C CG2 . VAL A 1 172 ? -11.109 2.977   0.178   1.0 98.94 ? 172 VAL A CG2 1 O43570 UNP 172 V 
ATOM 1331 N N   . LEU A 1 173 ? -9.707  -1.334  1.791   1.0 98.92 ? 173 LEU A N   1 O43570 UNP 173 L 
ATOM 1332 C CA  . LEU A 1 173 ? -9.639  -2.788  1.694   1.0 98.92 ? 173 LEU A CA  1 O43570 UNP 173 L 
ATOM 1333 C C   . LEU A 1 173 ? -10.876 -3.299  0.940   1.0 98.92 ? 173 LEU A C   1 O43570 UNP 173 L 
ATOM 1334 C CB  . LEU A 1 173 ? -9.531  -3.371  3.115   1.0 98.92 ? 173 LEU A CB  1 O43570 UNP 173 L 
ATOM 1335 O O   . LEU A 1 173 ? -11.986 -2.819  1.170   1.0 98.92 ? 173 LEU A O   1 O43570 UNP 173 L 
ATOM 1336 C CG  . LEU A 1 173 ? -8.260  -2.933  3.874   1.0 98.92 ? 173 LEU A CG  1 O43570 UNP 173 L 
ATOM 1337 C CD1 . LEU A 1 173 ? -8.363  -3.301  5.352   1.0 98.92 ? 173 LEU A CD1 1 O43570 UNP 173 L 
ATOM 1338 C CD2 . LEU A 1 173 ? -6.999  -3.570  3.291   1.0 98.92 ? 173 LEU A CD2 1 O43570 UNP 173 L 
ATOM 1339 N N   . ILE A 1 174 ? -10.692 -4.248  0.027   1.0 98.93 ? 174 ILE A N   1 O43570 UNP 174 I 
ATOM 1340 C CA  . ILE A 1 174 ? -11.757 -4.760  -0.843  1.0 98.93 ? 174 ILE A CA  1 O43570 UNP 174 I 
ATOM 1341 C C   . ILE A 1 174 ? -11.924 -6.254  -0.591  1.0 98.93 ? 174 ILE A C   1 O43570 UNP 174 I 
ATOM 1342 C CB  . ILE A 1 174 ? -11.440 -4.471  -2.327  1.0 98.93 ? 174 ILE A CB  1 O43570 UNP 174 I 
ATOM 1343 O O   . ILE A 1 174 ? -10.968 -7.017  -0.716  1.0 98.93 ? 174 ILE A O   1 O43570 UNP 174 I 
ATOM 1344 C CG1 . ILE A 1 174 ? -11.234 -2.962  -2.602  1.0 98.93 ? 174 ILE A CG1 1 O43570 UNP 174 I 
ATOM 1345 C CG2 . ILE A 1 174 ? -12.554 -5.040  -3.224  1.0 98.93 ? 174 ILE A CG2 1 O43570 UNP 174 I 
ATOM 1346 C CD1 . ILE A 1 174 ? -10.646 -2.654  -3.982  1.0 98.93 ? 174 ILE A CD1 1 O43570 UNP 174 I 
ATOM 1347 N N   . GLU A 1 175 ? -13.139 -6.687  -0.279  1.0 98.71 ? 175 GLU A N   1 O43570 UNP 175 E 
ATOM 1348 C CA  . GLU A 1 175 ? -13.502 -8.098  -0.146  1.0 98.71 ? 175 GLU A CA  1 O43570 UNP 175 E 
ATOM 1349 C C   . GLU A 1 175 ? -14.489 -8.532  -1.239  1.0 98.71 ? 175 GLU A C   1 O43570 UNP 175 E 
ATOM 1350 C CB  . GLU A 1 175 ? -14.000 -8.397  1.281   1.0 98.71 ? 175 GLU A CB  1 O43570 UNP 175 E 
ATOM 1351 O O   . GLU A 1 175 ? -15.144 -7.715  -1.893  1.0 98.71 ? 175 GLU A O   1 O43570 UNP 175 E 
ATOM 1352 C CG  . GLU A 1 175 ? -15.376 -7.788  1.586   1.0 98.71 ? 175 GLU A CG  1 O43570 UNP 175 E 
ATOM 1353 C CD  . GLU A 1 175 ? -15.857 -7.964  3.036   1.0 98.71 ? 175 GLU A CD  1 O43570 UNP 175 E 
ATOM 1354 O OE1 . GLU A 1 175 ? -17.068 -7.708  3.265   1.0 98.71 ? 175 GLU A OE1 1 O43570 UNP 175 E 
ATOM 1355 O OE2 . GLU A 1 175 ? -15.037 -8.317  3.913   1.0 98.71 ? 175 GLU A OE2 1 O43570 UNP 175 E 
ATOM 1356 N N   . MET A 1 176 ? -14.603 -9.842  -1.444  1.0 98.40 ? 176 MET A N   1 O43570 UNP 176 M 
ATOM 1357 C CA  . MET A 1 176 ? -15.610 -10.405 -2.338  1.0 98.40 ? 176 MET A CA  1 O43570 UNP 176 M 
ATOM 1358 C C   . MET A 1 176 ? -16.986 -10.384 -1.659  1.0 98.40 ? 176 MET A C   1 O43570 UNP 176 M 
ATOM 1359 C CB  . MET A 1 176 ? -15.190 -11.820 -2.744  1.0 98.40 ? 176 MET A CB  1 O43570 UNP 176 M 
ATOM 1360 O O   . MET A 1 176 ? -17.129 -10.804 -0.512  1.0 98.40 ? 176 MET A O   1 O43570 UNP 176 M 
ATOM 1361 C CG  . MET A 1 176 ? -16.053 -12.380 -3.880  1.0 98.40 ? 176 MET A CG  1 O43570 UNP 176 M 
ATOM 1362 S SD  . MET A 1 176 ? -15.733 -14.126 -4.253  1.0 98.40 ? 176 MET A SD  1 O43570 UNP 176 M 
ATOM 1363 C CE  . MET A 1 176 ? -14.012 -14.051 -4.813  1.0 98.40 ? 176 MET A CE  1 O43570 UNP 176 M 
ATOM 1364 N N   . GLY A 1 177 ? -18.011 -9.932  -2.375  1.0 98.50 ? 177 GLY A N   1 O43570 UNP 177 G 
ATOM 1365 C CA  . GLY A 1 177 ? -19.379 -9.857  -1.877  1.0 98.50 ? 177 GLY A CA  1 O43570 UNP 177 G 
ATOM 1366 C C   . GLY A 1 177 ? -20.361 -9.397  -2.952  1.0 98.50 ? 177 GLY A C   1 O43570 UNP 177 G 
ATOM 1367 O O   . GLY A 1 177 ? -20.437 -9.985  -4.029  1.0 98.50 ? 177 GLY A O   1 O43570 UNP 177 G 
ATOM 1368 N N   . SER A 1 178 ? -21.148 -8.364  -2.653  1.0 98.27 ? 178 SER A N   1 O43570 UNP 178 S 
ATOM 1369 C CA  . SER A 1 178 ? -22.152 -7.834  -3.587  1.0 98.27 ? 178 SER A CA  1 O43570 UNP 178 S 
ATOM 1370 C C   . SER A 1 178 ? -21.519 -7.116  -4.786  1.0 98.27 ? 178 SER A C   1 O43570 UNP 178 S 
ATOM 1371 C CB  . SER A 1 178 ? -23.108 -6.884  -2.863  1.0 98.27 ? 178 SER A CB  1 O43570 UNP 178 S 
ATOM 1372 O O   . SER A 1 178 ? -20.472 -6.484  -4.658  1.0 98.27 ? 178 SER A O   1 O43570 UNP 178 S 
ATOM 1373 O OG  . SER A 1 178 ? -23.740 -7.556  -1.789  1.0 98.27 ? 178 SER A OG  1 O43570 UNP 178 S 
ATOM 1374 N N   . PHE A 1 179 ? -22.188 -7.155  -5.945  1.0 98.73 ? 179 PHE A N   1 O43570 UNP 179 F 
ATOM 1375 C CA  . PHE A 1 179 ? -21.813 -6.325  -7.094  1.0 98.73 ? 179 PHE A CA  1 O43570 UNP 179 F 
ATOM 1376 C C   . PHE A 1 179 ? -21.804 -4.845  -6.708  1.0 98.73 ? 179 PHE A C   1 O43570 UNP 179 F 
ATOM 1377 C CB  . PHE A 1 179 ? -22.763 -6.566  -8.277  1.0 98.73 ? 179 PHE A CB  1 O43570 UNP 179 F 
ATOM 1378 O O   . PHE A 1 179 ? -22.748 -4.358  -6.083  1.0 98.73 ? 179 PHE A O   1 O43570 UNP 179 F 
ATOM 1379 C CG  . PHE A 1 179 ? -22.460 -5.694  -9.485  1.0 98.73 ? 179 PHE A CG  1 O43570 UNP 179 F 
ATOM 1380 C CD1 . PHE A 1 179 ? -23.116 -4.458  -9.652  1.0 98.73 ? 179 PHE A CD1 1 O43570 UNP 179 F 
ATOM 1381 C CD2 . PHE A 1 179 ? -21.501 -6.103  -10.430 1.0 98.73 ? 179 PHE A CD2 1 O43570 UNP 179 F 
ATOM 1382 C CE1 . PHE A 1 179 ? -22.816 -3.641  -10.758 1.0 98.73 ? 179 PHE A CE1 1 O43570 UNP 179 F 
ATOM 1383 C CE2 . PHE A 1 179 ? -21.192 -5.281  -11.528 1.0 98.73 ? 179 PHE A CE2 1 O43570 UNP 179 F 
ATOM 1384 C CZ  . PHE A 1 179 ? -21.853 -4.053  -11.694 1.0 98.73 ? 179 PHE A CZ  1 O43570 UNP 179 F 
ATOM 1385 N N   . ASN A 1 180 ? -20.754 -4.134  -7.113  1.0 98.73 ? 180 ASN A N   1 O43570 UNP 180 N 
ATOM 1386 C CA  . ASN A 1 180 ? -20.548 -2.740  -6.760  1.0 98.73 ? 180 ASN A CA  1 O43570 UNP 180 N 
ATOM 1387 C C   . ASN A 1 180 ? -20.595 -1.846  -8.008  1.0 98.73 ? 180 ASN A C   1 O43570 UNP 180 N 
ATOM 1388 C CB  . ASN A 1 180 ? -19.237 -2.641  -5.992  1.0 98.73 ? 180 ASN A CB  1 O43570 UNP 180 N 
ATOM 1389 O O   . ASN A 1 180 ? -19.619 -1.801  -8.765  1.0 98.73 ? 180 ASN A O   1 O43570 UNP 180 N 
ATOM 1390 C CG  . ASN A 1 180 ? -19.080 -1.294  -5.319  1.0 98.73 ? 180 ASN A CG  1 O43570 UNP 180 N 
ATOM 1391 N ND2 . ASN A 1 180 ? -18.612 -1.284  -4.096  1.0 98.73 ? 180 ASN A ND2 1 O43570 UNP 180 N 
ATOM 1392 O OD1 . ASN A 1 180 ? -19.373 -0.253  -5.891  1.0 98.73 ? 180 ASN A OD1 1 O43570 UNP 180 N 
ATOM 1393 N N   . PRO A 1 181 ? -21.701 -1.111  -8.229  1.0 98.70 ? 181 PRO A N   1 O43570 UNP 181 P 
ATOM 1394 C CA  . PRO A 1 181 ? -21.850 -0.242  -9.393  1.0 98.70 ? 181 PRO A CA  1 O43570 UNP 181 P 
ATOM 1395 C C   . PRO A 1 181 ? -20.810 0.879   -9.464  1.0 98.70 ? 181 PRO A C   1 O43570 UNP 181 P 
ATOM 1396 C CB  . PRO A 1 181 ? -23.261 0.347   -9.283  1.0 98.70 ? 181 PRO A CB  1 O43570 UNP 181 P 
ATOM 1397 O O   . PRO A 1 181 ? -20.484 1.335   -10.555 1.0 98.70 ? 181 PRO A O   1 O43570 UNP 181 P 
ATOM 1398 C CG  . PRO A 1 181 ? -24.020 -0.656  -8.420  1.0 98.70 ? 181 PRO A CG  1 O43570 UNP 181 P 
ATOM 1399 C CD  . PRO A 1 181 ? -22.943 -1.160  -7.469  1.0 98.70 ? 181 PRO A CD  1 O43570 UNP 181 P 
ATOM 1400 N N   . SER A 1 182 ? -20.291 1.339   -8.324  1.0 98.71 ? 182 SER A N   1 O43570 UNP 182 S 
ATOM 1401 C CA  . SER A 1 182 ? -19.339 2.452   -8.258  1.0 98.71 ? 182 SER A CA  1 O43570 UNP 182 S 
ATOM 1402 C C   . SER A 1 182 ? -17.959 2.032   -8.746  1.0 98.71 ? 182 SER A C   1 O43570 UNP 182 S 
ATOM 1403 C CB  . SER A 1 182 ? -19.254 2.985   -6.828  1.0 98.71 ? 182 SER A CB  1 O43570 UNP 182 S 
ATOM 1404 O O   . SER A 1 182 ? -17.354 2.730   -9.555  1.0 98.71 ? 182 SER A O   1 O43570 UNP 182 S 
ATOM 1405 O OG  . SER A 1 182 ? -20.562 3.215   -6.351  1.0 98.71 ? 182 SER A OG  1 O43570 UNP 182 S 
ATOM 1406 N N   . TYR A 1 183 ? -17.499 0.849   -8.332  1.0 98.79 ? 183 TYR A N   1 O43570 UNP 183 Y 
ATOM 1407 C CA  . TYR A 1 183 ? -16.265 0.251   -8.844  1.0 98.79 ? 183 TYR A CA  1 O43570 UNP 183 Y 
ATOM 1408 C C   . TYR A 1 183 ? -16.376 -0.119  -10.329 1.0 98.79 ? 183 TYR A C   1 O43570 UNP 183 Y 
ATOM 1409 C CB  . TYR A 1 183 ? -15.911 -0.972  -7.995  1.0 98.79 ? 183 TYR A CB  1 O43570 UNP 183 Y 
ATOM 1410 O O   . TYR A 1 183 ? -15.407 0.022   -11.078 1.0 98.79 ? 183 TYR A O   1 O43570 UNP 183 Y 
ATOM 1411 C CG  . TYR A 1 183 ? -15.130 -0.622  -6.746  1.0 98.79 ? 183 TYR A CG  1 O43570 UNP 183 Y 
ATOM 1412 C CD1 . TYR A 1 183 ? -13.732 -0.775  -6.746  1.0 98.79 ? 183 TYR A CD1 1 O43570 UNP 183 Y 
ATOM 1413 C CD2 . TYR A 1 183 ? -15.772 -0.091  -5.611  1.0 98.79 ? 183 TYR A CD2 1 O43570 UNP 183 Y 
ATOM 1414 C CE1 . TYR A 1 183 ? -12.977 -0.441  -5.610  1.0 98.79 ? 183 TYR A CE1 1 O43570 UNP 183 Y 
ATOM 1415 C CE2 . TYR A 1 183 ? -15.021 0.254   -4.472  1.0 98.79 ? 183 TYR A CE2 1 O43570 UNP 183 Y 
ATOM 1416 O OH  . TYR A 1 183 ? -12.881 0.418   -3.387  1.0 98.79 ? 183 TYR A OH  1 O43570 UNP 183 Y 
ATOM 1417 C CZ  . TYR A 1 183 ? -13.622 0.073   -4.469  1.0 98.79 ? 183 TYR A CZ  1 O43570 UNP 183 Y 
ATOM 1418 N N   . ASP A 1 184 ? -17.569 -0.504  -10.793 1.0 98.72 ? 184 ASP A N   1 O43570 UNP 184 D 
ATOM 1419 C CA  . ASP A 1 184 ? -17.804 -0.839  -12.200 1.0 98.72 ? 184 ASP A CA  1 O43570 UNP 184 D 
ATOM 1420 C C   . ASP A 1 184 ? -17.593 0.348   -13.155 1.0 98.72 ? 184 ASP A C   1 O43570 UNP 184 D 
ATOM 1421 C CB  . ASP A 1 184 ? -19.207 -1.431  -12.372 1.0 98.72 ? 184 ASP A CB  1 O43570 UNP 184 D 
ATOM 1422 O O   . ASP A 1 184 ? -17.199 0.162   -14.307 1.0 98.72 ? 184 ASP A O   1 O43570 UNP 184 D 
ATOM 1423 C CG  . ASP A 1 184 ? -19.205 -2.463  -13.496 1.0 98.72 ? 184 ASP A CG  1 O43570 UNP 184 D 
ATOM 1424 O OD1 . ASP A 1 184 ? -18.433 -3.438  -13.341 1.0 98.72 ? 184 ASP A OD1 1 O43570 UNP 184 D 
ATOM 1425 O OD2 . ASP A 1 184 ? -19.982 -2.283  -14.458 1.0 98.72 ? 184 ASP A OD2 1 O43570 UNP 184 D 
ATOM 1426 N N   . LYS A 1 185 ? -17.739 1.588   -12.662 1.0 98.67 ? 185 LYS A N   1 O43570 UNP 185 K 
ATOM 1427 C CA  . LYS A 1 185 ? -17.398 2.815   -13.410 1.0 98.67 ? 185 LYS A CA  1 O43570 UNP 185 K 
ATOM 1428 C C   . LYS A 1 185 ? -15.915 2.878   -13.795 1.0 98.67 ? 185 LYS A C   1 O43570 UNP 185 K 
ATOM 1429 C CB  . LYS A 1 185 ? -17.774 4.066   -12.597 1.0 98.67 ? 185 LYS A CB  1 O43570 UNP 185 K 
ATOM 1430 O O   . LYS A 1 185 ? -15.566 3.573   -14.741 1.0 98.67 ? 185 LYS A O   1 O43570 UNP 185 K 
ATOM 1431 C CG  . LYS A 1 185 ? -19.273 4.138   -12.269 1.0 98.67 ? 185 LYS A CG  1 O43570 UNP 185 K 
ATOM 1432 C CD  . LYS A 1 185 ? -19.571 5.284   -11.300 1.0 98.67 ? 185 LYS A CD  1 O43570 UNP 185 K 
ATOM 1433 C CE  . LYS A 1 185 ? -21.036 5.257   -10.856 1.0 98.67 ? 185 LYS A CE  1 O43570 UNP 185 K 
ATOM 1434 N NZ  . LYS A 1 185 ? -21.326 6.292   -9.831  1.0 98.67 ? 185 LYS A NZ  1 O43570 UNP 185 K 
ATOM 1435 N N   . ILE A 1 186 ? -15.050 2.144   -13.089 1.0 98.80 ? 186 ILE A N   1 O43570 UNP 186 I 
ATOM 1436 C CA  . ILE A 1 186 ? -13.642 1.935   -13.452 1.0 98.80 ? 186 ILE A CA  1 O43570 UNP 186 I 
ATOM 1437 C C   . ILE A 1 186 ? -13.484 0.600   -14.188 1.0 98.80 ? 186 ILE A C   1 O43570 UNP 186 I 
ATOM 1438 C CB  . ILE A 1 186 ? -12.735 2.006   -12.199 1.0 98.80 ? 186 ILE A CB  1 O43570 UNP 186 I 
ATOM 1439 O O   . ILE A 1 186 ? -12.860 0.550   -15.249 1.0 98.80 ? 186 ILE A O   1 O43570 UNP 186 I 
ATOM 1440 C CG1 . ILE A 1 186 ? -12.855 3.383   -11.501 1.0 98.80 ? 186 ILE A CG1 1 O43570 UNP 186 I 
ATOM 1441 C CG2 . ILE A 1 186 ? -11.266 1.729   -12.586 1.0 98.80 ? 186 ILE A CG2 1 O43570 UNP 186 I 
ATOM 1442 C CD1 . ILE A 1 186 ? -12.166 3.441   -10.130 1.0 98.80 ? 186 ILE A CD1 1 O43570 UNP 186 I 
ATOM 1443 N N   . PHE A 1 187 ? -14.044 -0.487  -13.646 1.0 98.71 ? 187 PHE A N   1 O43570 UNP 187 F 
ATOM 1444 C CA  . PHE A 1 187 ? -13.780 -1.843  -14.140 1.0 98.71 ? 187 PHE A CA  1 O43570 UNP 187 F 
ATOM 1445 C C   . PHE A 1 187 ? -14.288 -2.090  -15.564 1.0 98.71 ? 187 PHE A C   1 O43570 UNP 187 F 
ATOM 1446 C CB  . PHE A 1 187 ? -14.317 -2.885  -13.159 1.0 98.71 ? 187 PHE A CB  1 O43570 UNP 187 F 
ATOM 1447 O O   . PHE A 1 187 ? -13.619 -2.762  -16.352 1.0 98.71 ? 187 PHE A O   1 O43570 UNP 187 F 
ATOM 1448 C CG  . PHE A 1 187 ? -13.716 -2.868  -11.762 1.0 98.71 ? 187 PHE A CG  1 O43570 UNP 187 F 
ATOM 1449 C CD1 . PHE A 1 187 ? -12.493 -2.221  -11.471 1.0 98.71 ? 187 PHE A CD1 1 O43570 UNP 187 F 
ATOM 1450 C CD2 . PHE A 1 187 ? -14.375 -3.580  -10.745 1.0 98.71 ? 187 PHE A CD2 1 O43570 UNP 187 F 
ATOM 1451 C CE1 . PHE A 1 187 ? -11.937 -2.301  -10.185 1.0 98.71 ? 187 PHE A CE1 1 O43570 UNP 187 F 
ATOM 1452 C CE2 . PHE A 1 187 ? -13.806 -3.678  -9.464  1.0 98.71 ? 187 PHE A CE2 1 O43570 UNP 187 F 
ATOM 1453 C CZ  . PHE A 1 187 ? -12.582 -3.049  -9.187  1.0 98.71 ? 187 PHE A CZ  1 O43570 UNP 187 F 
ATOM 1454 N N   . SER A 1 188 ? -15.392 -1.449  -15.948 1.0 98.39 ? 188 SER A N   1 O43570 UNP 188 S 
ATOM 1455 C CA  . SER A 1 188 ? -15.912 -1.478  -17.321 1.0 98.39 ? 188 SER A CA  1 O43570 UNP 188 S 
ATOM 1456 C C   . SER A 1 188 ? -14.942 -0.904  -18.365 1.0 98.39 ? 188 SER A C   1 O43570 UNP 188 S 
ATOM 1457 C CB  . SER A 1 188 ? -17.248 -0.735  -17.389 1.0 98.39 ? 188 SER A CB  1 O43570 UNP 188 S 
ATOM 1458 O O   . SER A 1 188 ? -15.102 -1.166  -19.554 1.0 98.39 ? 188 SER A O   1 O43570 UNP 188 S 
ATOM 1459 O OG  . SER A 1 188 ? -17.091 0.605   -16.968 1.0 98.39 ? 188 SER A OG  1 O43570 UNP 188 S 
ATOM 1460 N N   . HIS A 1 189 ? -13.901 -0.169  -17.957 1.0 98.67 ? 189 HIS A N   1 O43570 UNP 189 H 
ATOM 1461 C CA  . HIS A 1 189 ? -12.890 0.391   -18.855 1.0 98.67 ? 189 HIS A CA  1 O43570 UNP 189 H 
ATOM 1462 C C   . HIS A 1 189 ? -11.596 -0.442  -18.946 1.0 98.67 ? 189 HIS A C   1 O43570 UNP 189 H 
ATOM 1463 C CB  . HIS A 1 189 ? -12.615 1.847   -18.459 1.0 98.67 ? 189 HIS A CB  1 O43570 UNP 189 H 
ATOM 1464 O O   . HIS A 1 189 ? -10.759 -0.147  -19.803 1.0 98.67 ? 189 HIS A O   1 O43570 UNP 189 H 
ATOM 1465 C CG  . HIS A 1 189 ? -13.771 2.778   -18.731 1.0 98.67 ? 189 HIS A CG  1 O43570 UNP 189 H 
ATOM 1466 C CD2 . HIS A 1 189 ? -14.855 3.015   -17.926 1.0 98.67 ? 189 HIS A CD2 1 O43570 UNP 189 H 
ATOM 1467 N ND1 . HIS A 1 189 ? -13.899 3.599   -19.828 1.0 98.67 ? 189 HIS A ND1 1 O43570 UNP 189 H 
ATOM 1468 C CE1 . HIS A 1 189 ? -15.024 4.316   -19.686 1.0 98.67 ? 189 HIS A CE1 1 O43570 UNP 189 H 
ATOM 1469 N NE2 . HIS A 1 189 ? -15.637 4.004   -18.539 1.0 98.67 ? 189 HIS A NE2 1 O43570 UNP 189 H 
ATOM 1470 N N   . LEU A 1 190 ? -11.418 -1.500  -18.138 1.0 98.71 ? 190 LEU A N   1 O43570 UNP 190 L 
ATOM 1471 C CA  . LEU A 1 190 ? -10.164 -2.281  -18.084 1.0 98.71 ? 190 LEU A CA  1 O43570 UNP 190 L 
ATOM 1472 C C   . LEU A 1 190 ? -9.780  -2.898  -19.433 1.0 98.71 ? 190 LEU A C   1 O43570 UNP 190 L 
ATOM 1473 C CB  . LEU A 1 190 ? -10.272 -3.400  -17.034 1.0 98.71 ? 190 LEU A CB  1 O43570 UNP 190 L 
ATOM 1474 O O   . LEU A 1 190 ? -8.607  -2.941  -19.798 1.0 98.71 ? 190 LEU A O   1 O43570 UNP 190 L 
ATOM 1475 C CG  . LEU A 1 190 ? -10.429 -2.909  -15.591 1.0 98.71 ? 190 LEU A CG  1 O43570 UNP 190 L 
ATOM 1476 C CD1 . LEU A 1 190 ? -10.617 -4.098  -14.649 1.0 98.71 ? 190 LEU A CD1 1 O43570 UNP 190 L 
ATOM 1477 C CD2 . LEU A 1 190 ? -9.246  -2.081  -15.108 1.0 98.71 ? 190 LEU A CD2 1 O43570 UNP 190 L 
ATOM 1478 N N   . GLN A 1 191 ? -10.773 -3.310  -20.218 1.0 97.93 ? 191 GLN A N   1 O43570 UNP 191 Q 
ATOM 1479 C CA  . GLN A 1 191 ? -10.585 -3.855  -21.565 1.0 97.93 ? 191 GLN A CA  1 O43570 UNP 191 Q 
ATOM 1480 C C   . GLN A 1 191 ? -9.887  -2.889  -22.540 1.0 97.93 ? 191 GLN A C   1 O43570 UNP 191 Q 
ATOM 1481 C CB  . GLN A 1 191 ? -11.961 -4.278  -22.096 1.0 97.93 ? 191 GLN A CB  1 O43570 UNP 191 Q 
ATOM 1482 O O   . GLN A 1 191 ? -9.246  -3.340  -23.487 1.0 97.93 ? 191 GLN A O   1 O43570 UNP 191 Q 
ATOM 1483 C CG  . GLN A 1 191 ? -12.894 -3.074  -22.350 1.0 97.93 ? 191 GLN A CG  1 O43570 UNP 191 Q 
ATOM 1484 C CD  . GLN A 1 191 ? -14.364 -3.349  -22.066 1.0 97.93 ? 191 GLN A CD  1 O43570 UNP 191 Q 
ATOM 1485 N NE2 . GLN A 1 191 ? -15.195 -2.341  -22.162 1.0 97.93 ? 191 GLN A NE2 1 O43570 UNP 191 Q 
ATOM 1486 O OE1 . GLN A 1 191 ? -14.784 -4.451  -21.758 1.0 97.93 ? 191 GLN A OE1 1 O43570 UNP 191 Q 
ATOM 1487 N N   . HIS A 1 192 ? -9.986  -1.575  -22.308 1.0 98.46 ? 192 HIS A N   1 O43570 UNP 192 H 
ATOM 1488 C CA  . HIS A 1 192 ? -9.370  -0.537  -23.140 1.0 98.46 ? 192 HIS A CA  1 O43570 UNP 192 H 
ATOM 1489 C C   . HIS A 1 192 ? -7.943  -0.185  -22.700 1.0 98.46 ? 192 HIS A C   1 O43570 UNP 192 H 
ATOM 1490 C CB  . HIS A 1 192 ? -10.272 0.704   -23.147 1.0 98.46 ? 192 HIS A CB  1 O43570 UNP 192 H 
ATOM 1491 O O   . HIS A 1 192 ? -7.231  0.498   -23.429 1.0 98.46 ? 192 HIS A O   1 O43570 UNP 192 H 
ATOM 1492 C CG  . HIS A 1 192 ? -11.662 0.423   -23.654 1.0 98.46 ? 192 HIS A CG  1 O43570 UNP 192 H 
ATOM 1493 C CD2 . HIS A 1 192 ? -12.837 0.632   -22.983 1.0 98.46 ? 192 HIS A CD2 1 O43570 UNP 192 H 
ATOM 1494 N ND1 . HIS A 1 192 ? -11.983 -0.141  -24.868 1.0 98.46 ? 192 HIS A ND1 1 O43570 UNP 192 H 
ATOM 1495 C CE1 . HIS A 1 192 ? -13.318 -0.269  -24.928 1.0 98.46 ? 192 HIS A CE1 1 O43570 UNP 192 H 
ATOM 1496 N NE2 . HIS A 1 192 ? -13.881 0.181   -23.796 1.0 98.46 ? 192 HIS A NE2 1 O43570 UNP 192 H 
ATOM 1497 N N   . VAL A 1 193 ? -7.517  -0.674  -21.532 1.0 98.69 ? 193 VAL A N   1 O43570 UNP 193 V 
ATOM 1498 C CA  . VAL A 1 193 ? -6.173  -0.479  -20.969 1.0 98.69 ? 193 VAL A CA  1 O43570 UNP 193 V 
ATOM 1499 C C   . VAL A 1 193 ? -5.487  -1.820  -20.686 1.0 98.69 ? 193 VAL A C   1 O43570 UNP 193 V 
ATOM 1500 C CB  . VAL A 1 193 ? -6.188  0.478   -19.760 1.0 98.69 ? 193 VAL A CB  1 O43570 UNP 193 V 
ATOM 1501 O O   . VAL A 1 193 ? -4.706  -1.960  -19.747 1.0 98.69 ? 193 VAL A O   1 O43570 UNP 193 V 
ATOM 1502 C CG1 . VAL A 1 193 ? -6.629  1.882   -20.182 1.0 98.69 ? 193 VAL A CG1 1 O43570 UNP 193 V 
ATOM 1503 C CG2 . VAL A 1 193 ? -7.112  0.008   -18.631 1.0 98.69 ? 193 VAL A CG2 1 O43570 UNP 193 V 
ATOM 1504 N N   . LYS A 1 194 ? -5.776  -2.835  -21.507 1.0 98.69 ? 194 LYS A N   1 O43570 UNP 194 K 
ATOM 1505 C CA  . LYS A 1 194 ? -5.274  -4.205  -21.343 1.0 98.69 ? 194 LYS A CA  1 O43570 UNP 194 K 
ATOM 1506 C C   . LYS A 1 194 ? -3.749  -4.272  -21.245 1.0 98.69 ? 194 LYS A C   1 O43570 UNP 194 K 
ATOM 1507 C CB  . LYS A 1 194 ? -5.810  -5.065  -22.496 1.0 98.69 ? 194 LYS A CB  1 O43570 UNP 194 K 
ATOM 1508 O O   . LYS A 1 194 ? -3.242  -4.995  -20.399 1.0 98.69 ? 194 LYS A O   1 O43570 UNP 194 K 
ATOM 1509 C CG  . LYS A 1 194 ? -5.258  -6.501  -22.463 1.0 98.69 ? 194 LYS A CG  1 O43570 UNP 194 K 
ATOM 1510 C CD  . LYS A 1 194 ? -5.935  -7.433  -23.478 1.0 98.69 ? 194 LYS A CD  1 O43570 UNP 194 K 
ATOM 1511 C CE  . LYS A 1 194 ? -7.423  -7.678  -23.193 1.0 98.69 ? 194 LYS A CE  1 O43570 UNP 194 K 
ATOM 1512 N NZ  . LYS A 1 194 ? -7.629  -8.378  -21.898 1.0 98.69 ? 194 LYS A NZ  1 O43570 UNP 194 K 
ATOM 1513 N N   . TYR A 1 195 ? -3.020  -3.530  -22.070 1.0 98.67 ? 195 TYR A N   1 O43570 UNP 195 Y 
ATOM 1514 C CA  . TYR A 1 195 ? -1.556  -3.582  -22.136 1.0 98.67 ? 195 TYR A CA  1 O43570 UNP 195 Y 
ATOM 1515 C C   . TYR A 1 195 ? -0.902  -2.328  -21.559 1.0 98.67 ? 195 TYR A C   1 O43570 UNP 195 Y 
ATOM 1516 C CB  . TYR A 1 195 ? -1.114  -3.830  -23.581 1.0 98.67 ? 195 TYR A CB  1 O43570 UNP 195 Y 
ATOM 1517 O O   . TYR A 1 195 ? -1.476  -1.237  -21.574 1.0 98.67 ? 195 TYR A O   1 O43570 UNP 195 Y 
ATOM 1518 C CG  . TYR A 1 195 ? -1.604  -5.149  -24.141 1.0 98.67 ? 195 TYR A CG  1 O43570 UNP 195 Y 
ATOM 1519 C CD1 . TYR A 1 195 ? -0.959  -6.348  -23.779 1.0 98.67 ? 195 TYR A CD1 1 O43570 UNP 195 Y 
ATOM 1520 C CD2 . TYR A 1 195 ? -2.707  -5.179  -25.014 1.0 98.67 ? 195 TYR A CD2 1 O43570 UNP 195 Y 
ATOM 1521 C CE1 . TYR A 1 195 ? -1.416  -7.578  -24.288 1.0 98.67 ? 195 TYR A CE1 1 O43570 UNP 195 Y 
ATOM 1522 C CE2 . TYR A 1 195 ? -3.162  -6.406  -25.532 1.0 98.67 ? 195 TYR A CE2 1 O43570 UNP 195 Y 
ATOM 1523 O OH  . TYR A 1 195 ? -2.976  -8.786  -25.660 1.0 98.67 ? 195 TYR A OH  1 O43570 UNP 195 Y 
ATOM 1524 C CZ  . TYR A 1 195 ? -2.519  -7.606  -25.168 1.0 98.67 ? 195 TYR A CZ  1 O43570 UNP 195 Y 
ATOM 1525 N N   . LYS A 1 196 ? 0.345   -2.466  -21.101 1.0 98.25 ? 196 LYS A N   1 O43570 UNP 196 K 
ATOM 1526 C CA  . LYS A 1 196 ? 1.152   -1.353  -20.597 1.0 98.25 ? 196 LYS A CA  1 O43570 UNP 196 K 
ATOM 1527 C C   . LYS A 1 196 ? 1.222   -0.219  -21.624 1.0 98.25 ? 196 LYS A C   1 O43570 UNP 196 K 
ATOM 1528 C CB  . LYS A 1 196 ? 2.549   -1.867  -20.231 1.0 98.25 ? 196 LYS A CB  1 O43570 UNP 196 K 
ATOM 1529 O O   . LYS A 1 196 ? 1.543   -0.433  -22.793 1.0 98.25 ? 196 LYS A O   1 O43570 UNP 196 K 
ATOM 1530 C CG  . LYS A 1 196 ? 3.455   -0.755  -19.689 1.0 98.25 ? 196 LYS A CG  1 O43570 UNP 196 K 
ATOM 1531 C CD  . LYS A 1 196 ? 4.849   -1.299  -19.386 1.0 98.25 ? 196 LYS A CD  1 O43570 UNP 196 K 
ATOM 1532 C CE  . LYS A 1 196 ? 5.749   -0.159  -18.911 1.0 98.25 ? 196 LYS A CE  1 O43570 UNP 196 K 
ATOM 1533 N NZ  . LYS A 1 196 ? 7.170   -0.565  -18.970 1.0 98.25 ? 196 LYS A NZ  1 O43570 UNP 196 K 
ATOM 1534 N N   . GLY A 1 197 ? 0.981   1.001   -21.154 1.0 97.74 ? 197 GLY A N   1 O43570 UNP 197 G 
ATOM 1535 C CA  . GLY A 1 197 ? 0.995   2.227   -21.950 1.0 97.74 ? 197 GLY A CA  1 O43570 UNP 197 G 
ATOM 1536 C C   . GLY A 1 197 ? -0.320  2.533   -22.666 1.0 97.74 ? 197 GLY A C   1 O43570 UNP 197 G 
ATOM 1537 O O   . GLY A 1 197 ? -0.423  3.599   -23.263 1.0 97.74 ? 197 GLY A O   1 O43570 UNP 197 G 
ATOM 1538 N N   . GLN A 1 198 ? -1.319  1.646   -22.611 1.0 98.61 ? 198 GLN A N   1 O43570 UNP 198 Q 
ATOM 1539 C CA  . GLN A 1 198 ? -2.656  1.969   -23.100 1.0 98.61 ? 198 GLN A CA  1 O43570 UNP 198 Q 
ATOM 1540 C C   . GLN A 1 198 ? -3.383  2.909   -22.137 1.0 98.61 ? 198 GLN A C   1 O43570 UNP 198 Q 
ATOM 1541 C CB  . GLN A 1 198 ? -3.483  0.705   -23.352 1.0 98.61 ? 198 GLN A CB  1 O43570 UNP 198 Q 
ATOM 1542 O O   . GLN A 1 198 ? -3.214  2.843   -20.913 1.0 98.61 ? 198 GLN A O   1 O43570 UNP 198 Q 
ATOM 1543 C CG  . GLN A 1 198 ? -2.966  -0.097  -24.552 1.0 98.61 ? 198 GLN A CG  1 O43570 UNP 198 Q 
ATOM 1544 C CD  . GLN A 1 198 ? -3.854  -1.294  -24.873 1.0 98.61 ? 198 GLN A CD  1 O43570 UNP 198 Q 
ATOM 1545 N NE2 . GLN A 1 198 ? -3.967  -1.674  -26.126 1.0 98.61 ? 198 GLN A NE2 1 O43570 UNP 198 Q 
ATOM 1546 O OE1 . GLN A 1 198 ? -4.430  -1.944  -24.015 1.0 98.61 ? 198 GLN A OE1 1 O43570 UNP 198 Q 
ATOM 1547 N N   . GLU A 1 199 ? -4.220  3.761   -22.722 1.0 98.74 ? 199 GLU A N   1 O43570 UNP 199 E 
ATOM 1548 C CA  . GLU A 1 199 ? -4.981  4.789   -22.028 1.0 98.74 ? 199 GLU A CA  1 O43570 UNP 199 E 
ATOM 1549 C C   . GLU A 1 199 ? -6.448  4.779   -22.472 1.0 98.74 ? 199 GLU A C   1 O43570 UNP 199 E 
ATOM 1550 C CB  . GLU A 1 199 ? -4.357  6.173   -22.264 1.0 98.74 ? 199 GLU A CB  1 O43570 UNP 199 E 
ATOM 1551 O O   . GLU A 1 199 ? -6.763  4.485   -23.626 1.0 98.74 ? 199 GLU A O   1 O43570 UNP 199 E 
ATOM 1552 C CG  . GLU A 1 199 ? -2.943  6.287   -21.673 1.0 98.74 ? 199 GLU A CG  1 O43570 UNP 199 E 
ATOM 1553 C CD  . GLU A 1 199 ? -2.326  7.689   -21.783 1.0 98.74 ? 199 GLU A CD  1 O43570 UNP 199 E 
ATOM 1554 O OE1 . GLU A 1 199 ? -1.369  7.936   -21.011 1.0 98.74 ? 199 GLU A OE1 1 O43570 UNP 199 E 
ATOM 1555 O OE2 . GLU A 1 199 ? -2.816  8.514   -22.586 1.0 98.74 ? 199 GLU A OE2 1 O43570 UNP 199 E 
ATOM 1556 N N   . ALA A 1 200 ? -7.345  5.129   -21.553 1.0 98.69 ? 200 ALA A N   1 O43570 UNP 200 A 
ATOM 1557 C CA  . ALA A 1 200 ? -8.769  5.307   -21.799 1.0 98.69 ? 200 ALA A CA  1 O43570 UNP 200 A 
ATOM 1558 C C   . ALA A 1 200 ? -9.299  6.518   -21.022 1.0 98.69 ? 200 ALA A C   1 O43570 UNP 200 A 
ATOM 1559 C CB  . ALA A 1 200 ? -9.509  4.016   -21.422 1.0 98.69 ? 200 ALA A CB  1 O43570 UNP 200 A 
ATOM 1560 O O   . ALA A 1 200 ? -8.697  6.960   -20.046 1.0 98.69 ? 200 ALA A O   1 O43570 UNP 200 A 
ATOM 1561 N N   . PHE A 1 201 ? -10.451 7.044   -21.434 1.0 98.68 ? 201 PHE A N   1 O43570 UNP 201 F 
ATOM 1562 C CA  . PHE A 1 201 ? -11.132 8.124   -20.725 1.0 98.68 ? 201 PHE A CA  1 O43570 UNP 201 F 
ATOM 1563 C C   . PHE A 1 201 ? -12.335 7.593   -19.948 1.0 98.68 ? 201 PHE A C   1 O43570 UNP 201 F 
ATOM 1564 C CB  . PHE A 1 201 ? -11.527 9.227   -21.710 1.0 98.68 ? 201 PHE A CB  1 O43570 UNP 201 F 
ATOM 1565 O O   . PHE A 1 201 ? -13.196 6.922   -20.517 1.0 98.68 ? 201 PHE A O   1 O43570 UNP 201 F 
ATOM 1566 C CG  . PHE A 1 201 ? -10.354 10.071  -22.172 1.0 98.68 ? 201 PHE A CG  1 O43570 UNP 201 F 
ATOM 1567 C CD1 . PHE A 1 201 ? -9.711  10.941  -21.269 1.0 98.68 ? 201 PHE A CD1 1 O43570 UNP 201 F 
ATOM 1568 C CD2 . PHE A 1 201 ? -9.890  9.976   -23.497 1.0 98.68 ? 201 PHE A CD2 1 O43570 UNP 201 F 
ATOM 1569 C CE1 . PHE A 1 201 ? -8.619  11.718  -21.692 1.0 98.68 ? 201 PHE A CE1 1 O43570 UNP 201 F 
ATOM 1570 C CE2 . PHE A 1 201 ? -8.793  10.748  -23.918 1.0 98.68 ? 201 PHE A CE2 1 O43570 UNP 201 F 
ATOM 1571 C CZ  . PHE A 1 201 ? -8.159  11.620  -23.017 1.0 98.68 ? 201 PHE A CZ  1 O43570 UNP 201 F 
ATOM 1572 N N   . VAL A 1 202 ? -12.403 7.940   -18.663 1.0 98.70 ? 202 VAL A N   1 O43570 UNP 202 V 
ATOM 1573 C CA  . VAL A 1 202 ? -13.511 7.616   -17.755 1.0 98.70 ? 202 VAL A CA  1 O43570 UNP 202 V 
ATOM 1574 C C   . VAL A 1 202 ? -14.297 8.902   -17.469 1.0 98.70 ? 202 VAL A C   1 O43570 UNP 202 V 
ATOM 1575 C CB  . VAL A 1 202 ? -12.988 6.973   -16.456 1.0 98.70 ? 202 VAL A CB  1 O43570 UNP 202 V 
ATOM 1576 O O   . VAL A 1 202 ? -13.687 9.893   -17.053 1.0 98.70 ? 202 VAL A O   1 O43570 UNP 202 V 
ATOM 1577 C CG1 . VAL A 1 202 ? -14.127 6.594   -15.505 1.0 98.70 ? 202 VAL A CG1 1 O43570 UNP 202 V 
ATOM 1578 C CG2 . VAL A 1 202 ? -12.200 5.691   -16.758 1.0 98.70 ? 202 VAL A CG2 1 O43570 UNP 202 V 
ATOM 1579 N N   . PRO A 1 203 ? -15.620 8.949   -17.712 1.0 98.52 ? 203 PRO A N   1 O43570 UNP 203 P 
ATOM 1580 C CA  . PRO A 1 203 ? -16.451 10.084  -17.314 1.0 98.52 ? 203 PRO A CA  1 O43570 UNP 203 P 
ATOM 1581 C C   . PRO A 1 203 ? -16.401 10.319  -15.800 1.0 98.52 ? 203 PRO A C   1 O43570 UNP 203 P 
ATOM 1582 C CB  . PRO A 1 203 ? -17.874 9.746   -17.772 1.0 98.52 ? 203 PRO A CB  1 O43570 UNP 203 P 
ATOM 1583 O O   . PRO A 1 203 ? -16.326 9.368   -15.025 1.0 98.52 ? 203 PRO A O   1 O43570 UNP 203 P 
ATOM 1584 C CG  . PRO A 1 203 ? -17.660 8.723   -18.887 1.0 98.52 ? 203 PRO A CG  1 O43570 UNP 203 P 
ATOM 1585 C CD  . PRO A 1 203 ? -16.421 7.962   -18.421 1.0 98.52 ? 203 PRO A CD  1 O43570 UNP 203 P 
ATOM 1586 N N   . GLY A 1 204 ? -16.462 11.579  -15.368 1.0 98.65 ? 204 GLY A N   1 O43570 UNP 204 G 
ATOM 1587 C CA  . GLY A 1 204 ? -16.485 11.909  -13.945 1.0 98.65 ? 204 GLY A CA  1 O43570 UNP 204 G 
ATOM 1588 C C   . GLY A 1 204 ? -17.647 11.249  -13.201 1.0 98.65 ? 204 GLY A C   1 O43570 UNP 204 G 
ATOM 1589 O O   . GLY A 1 204 ? -18.781 11.216  -13.679 1.0 98.65 ? 204 GLY A O   1 O43570 UNP 204 G 
ATOM 1590 N N   . PHE A 1 205 ? -17.349 10.736  -12.015 1.0 98.80 ? 205 PHE A N   1 O43570 UNP 205 F 
ATOM 1591 C CA  . PHE A 1 205 ? -18.318 10.182  -11.082 1.0 98.80 ? 205 PHE A CA  1 O43570 UNP 205 F 
ATOM 1592 C C   . PHE A 1 205 ? -17.903 10.519  -9.650  1.0 98.80 ? 205 PHE A C   1 O43570 UNP 205 F 
ATOM 1593 C CB  . PHE A 1 205 ? -18.436 8.669   -11.300 1.0 98.80 ? 205 PHE A CB  1 O43570 UNP 205 F 
ATOM 1594 O O   . PHE A 1 205 ? -16.811 11.042  -9.417  1.0 98.80 ? 205 PHE A O   1 O43570 UNP 205 F 
ATOM 1595 C CG  . PHE A 1 205 ? -17.214 7.858   -10.901 1.0 98.80 ? 205 PHE A CG  1 O43570 UNP 205 F 
ATOM 1596 C CD1 . PHE A 1 205 ? -16.132 7.722   -11.792 1.0 98.80 ? 205 PHE A CD1 1 O43570 UNP 205 F 
ATOM 1597 C CD2 . PHE A 1 205 ? -17.168 7.220   -9.646  1.0 98.80 ? 205 PHE A CD2 1 O43570 UNP 205 F 
ATOM 1598 C CE1 . PHE A 1 205 ? -15.009 6.959   -11.430 1.0 98.80 ? 205 PHE A CE1 1 O43570 UNP 205 F 
ATOM 1599 C CE2 . PHE A 1 205 ? -16.052 6.446   -9.291  1.0 98.80 ? 205 PHE A CE2 1 O43570 UNP 205 F 
ATOM 1600 C CZ  . PHE A 1 205 ? -14.973 6.317   -10.181 1.0 98.80 ? 205 PHE A CZ  1 O43570 UNP 205 F 
ATOM 1601 N N   . ASN A 1 206 ? -18.770 10.221  -8.684  1.0 98.69 ? 206 ASN A N   1 O43570 UNP 206 N 
ATOM 1602 C CA  . ASN A 1 206 ? -18.451 10.459  -7.289  1.0 98.69 ? 206 ASN A CA  1 O43570 UNP 206 N 
ATOM 1603 C C   . ASN A 1 206 ? -17.462 9.423   -6.742  1.0 98.69 ? 206 ASN A C   1 O43570 UNP 206 N 
ATOM 1604 C CB  . ASN A 1 206 ? -19.751 10.573  -6.484  1.0 98.69 ? 206 ASN A CB  1 O43570 UNP 206 N 
ATOM 1605 O O   . ASN A 1 206 ? -17.830 8.283   -6.477  1.0 98.69 ? 206 ASN A O   1 O43570 UNP 206 N 
ATOM 1606 C CG  . ASN A 1 206 ? -19.482 10.980  -5.049  1.0 98.69 ? 206 ASN A CG  1 O43570 UNP 206 N 
ATOM 1607 N ND2 . ASN A 1 206 ? -20.450 10.854  -4.177  1.0 98.69 ? 206 ASN A ND2 1 O43570 UNP 206 N 
ATOM 1608 O OD1 . ASN A 1 206 ? -18.403 11.440  -4.712  1.0 98.69 ? 206 ASN A OD1 1 O43570 UNP 206 N 
ATOM 1609 N N   . ILE A 1 207 ? -16.210 9.844   -6.550  1.0 98.82 ? 207 ILE A N   1 O43570 UNP 207 I 
ATOM 1610 C CA  . ILE A 1 207 ? -15.124 9.015   -6.013  1.0 98.82 ? 207 ILE A CA  1 O43570 UNP 207 I 
ATOM 1611 C C   . ILE A 1 207 ? -15.395 8.603   -4.562  1.0 98.82 ? 207 ILE A C   1 O43570 UNP 207 I 
ATOM 1612 C CB  . ILE A 1 207 ? -13.774 9.763   -6.137  1.0 98.82 ? 207 ILE A CB  1 O43570 UNP 207 I 
ATOM 1613 O O   . ILE A 1 207 ? -14.908 7.566   -4.121  1.0 98.82 ? 207 ILE A O   1 O43570 UNP 207 I 
ATOM 1614 C CG1 . ILE A 1 207 ? -13.450 10.200  -7.582  1.0 98.82 ? 207 ILE A CG1 1 O43570 UNP 207 I 
ATOM 1615 C CG2 . ILE A 1 207 ? -12.612 8.916   -5.590  1.0 98.82 ? 207 ILE A CG2 1 O43570 UNP 207 I 
ATOM 1616 C CD1 . ILE A 1 207 ? -13.393 9.063   -8.611  1.0 98.82 ? 207 ILE A CD1 1 O43570 UNP 207 I 
ATOM 1617 N N   . GLU A 1 208 ? -16.200 9.369   -3.822  1.0 98.65 ? 208 GLU A N   1 O43570 UNP 208 E 
ATOM 1618 C CA  . GLU A 1 208 ? -16.583 9.020   -2.449  1.0 98.65 ? 208 GLU A CA  1 O43570 UNP 208 E 
ATOM 1619 C C   . GLU A 1 208 ? -17.391 7.714   -2.398  1.0 98.65 ? 208 GLU A C   1 O43570 UNP 208 E 
ATOM 1620 C CB  . GLU A 1 208 ? -17.354 10.194  -1.831  1.0 98.65 ? 208 GLU A CB  1 O43570 UNP 208 E 
ATOM 1621 O O   . GLU A 1 208 ? -17.317 6.990   -1.415  1.0 98.65 ? 208 GLU A O   1 O43570 UNP 208 E 
ATOM 1622 C CG  . GLU A 1 208 ? -17.440 10.109  -0.300  1.0 98.65 ? 208 GLU A CG  1 O43570 UNP 208 E 
ATOM 1623 C CD  . GLU A 1 208 ? -18.135 11.324  0.332   1.0 98.65 ? 208 GLU A CD  1 O43570 UNP 208 E 
ATOM 1624 O OE1 . GLU A 1 208 ? -18.244 11.335  1.579   1.0 98.65 ? 208 GLU A OE1 1 O43570 UNP 208 E 
ATOM 1625 O OE2 . GLU A 1 208 ? -18.546 12.241  -0.419  1.0 98.65 ? 208 GLU A OE2 1 O43570 UNP 208 E 
ATOM 1626 N N   . GLU A 1 209 ? -18.073 7.340   -3.487  1.0 98.62 ? 209 GLU A N   1 O43570 UNP 209 E 
ATOM 1627 C CA  . GLU A 1 209 ? -18.787 6.059   -3.598  1.0 98.62 ? 209 GLU A CA  1 O43570 UNP 209 E 
ATOM 1628 C C   . GLU A 1 209 ? -17.850 4.838   -3.678  1.0 98.62 ? 209 GLU A C   1 O43570 UNP 209 E 
ATOM 1629 C CB  . GLU A 1 209 ? -19.681 6.050   -4.845  1.0 98.62 ? 209 GLU A CB  1 O43570 UNP 209 E 
ATOM 1630 O O   . GLU A 1 209 ? -18.324 3.702   -3.664  1.0 98.62 ? 209 GLU A O   1 O43570 UNP 209 E 
ATOM 1631 C CG  . GLU A 1 209 ? -20.738 7.158   -4.941  1.0 98.62 ? 209 GLU A CG  1 O43570 UNP 209 E 
ATOM 1632 C CD  . GLU A 1 209 ? -21.424 7.207   -6.320  1.0 98.62 ? 209 GLU A CD  1 O43570 UNP 209 E 
ATOM 1633 O OE1 . GLU A 1 209 ? -22.319 8.061   -6.510  1.0 98.62 ? 209 GLU A OE1 1 O43570 UNP 209 E 
ATOM 1634 O OE2 . GLU A 1 209 ? -21.034 6.464   -7.254  1.0 98.62 ? 209 GLU A OE2 1 O43570 UNP 209 E 
ATOM 1635 N N   . LEU A 1 210 ? -16.536 5.055   -3.810  1.0 98.85 ? 210 LEU A N   1 O43570 UNP 210 L 
ATOM 1636 C CA  . LEU A 1 210 ? -15.520 4.005   -3.693  1.0 98.85 ? 210 LEU A CA  1 O43570 UNP 210 L 
ATOM 1637 C C   . LEU A 1 210 ? -15.063 3.800   -2.242  1.0 98.85 ? 210 LEU A C   1 O43570 UNP 210 L 
ATOM 1638 C CB  . LEU A 1 210 ? -14.300 4.342   -4.568  1.0 98.85 ? 210 LEU A CB  1 O43570 UNP 210 L 
ATOM 1639 O O   . LEU A 1 210 ? -14.339 2.849   -1.960  1.0 98.85 ? 210 LEU A O   1 O43570 UNP 210 L 
ATOM 1640 C CG  . LEU A 1 210 ? -14.588 4.650   -6.044  1.0 98.85 ? 210 LEU A CG  1 O43570 UNP 210 L 
ATOM 1641 C CD1 . LEU A 1 210 ? -13.263 4.922   -6.759  1.0 98.85 ? 210 LEU A CD1 1 O43570 UNP 210 L 
ATOM 1642 C CD2 . LEU A 1 210 ? -15.287 3.490   -6.755  1.0 98.85 ? 210 LEU A CD2 1 O43570 UNP 210 L 
ATOM 1643 N N   . LEU A 1 211 ? -15.429 4.704   -1.329  1.0 98.83 ? 211 LEU A N   1 O43570 UNP 211 L 
ATOM 1644 C CA  . LEU A 1 211 ? -15.076 4.606   0.081   1.0 98.83 ? 211 LEU A CA  1 O43570 UNP 211 L 
ATOM 1645 C C   . LEU A 1 211 ? -16.048 3.672   0.819   1.0 98.83 ? 211 LEU A C   1 O43570 UNP 211 L 
ATOM 1646 C CB  . LEU A 1 211 ? -15.027 6.004   0.722   1.0 98.83 ? 211 LEU A CB  1 O43570 UNP 211 L 
ATOM 1647 O O   . LEU A 1 211 ? -17.199 3.515   0.407   1.0 98.83 ? 211 LEU A O   1 O43570 UNP 211 L 
ATOM 1648 C CG  . LEU A 1 211 ? -14.070 6.999   0.042   1.0 98.83 ? 211 LEU A CG  1 O43570 UNP 211 L 
ATOM 1649 C CD1 . LEU A 1 211 ? -13.975 8.263   0.893   1.0 98.83 ? 211 LEU A CD1 1 O43570 UNP 211 L 
ATOM 1650 C CD2 . LEU A 1 211 ? -12.656 6.438   -0.120  1.0 98.83 ? 211 LEU A CD2 1 O43570 UNP 211 L 
ATOM 1651 N N   . PRO A 1 212 ? -15.604 3.039   1.915   1.0 98.62 ? 212 PRO A N   1 O43570 UNP 212 P 
ATOM 1652 C CA  . PRO A 1 212 ? -16.451 2.151   2.693   1.0 98.62 ? 212 PRO A CA  1 O43570 UNP 212 P 
ATOM 1653 C C   . PRO A 1 212 ? -17.421 2.919   3.587   1.0 98.62 ? 212 PRO A C   1 O43570 UNP 212 P 
ATOM 1654 C CB  . PRO A 1 212 ? -15.479 1.302   3.507   1.0 98.62 ? 212 PRO A CB  1 O43570 UNP 212 P 
ATOM 1655 O O   . PRO A 1 212 ? -17.269 4.110   3.861   1.0 98.62 ? 212 PRO A O   1 O43570 UNP 212 P 
ATOM 1656 C CG  . PRO A 1 212 ? -14.332 2.275   3.767   1.0 98.62 ? 212 PRO A CG  1 O43570 UNP 212 P 
ATOM 1657 C CD  . PRO A 1 212 ? -14.266 3.092   2.484   1.0 98.62 ? 212 PRO A CD  1 O43570 UNP 212 P 
ATOM 1658 N N   . GLU A 1 213 ? -18.389 2.185   4.126   1.0 97.38 ? 213 GLU A N   1 O43570 UNP 213 E 
ATOM 1659 C CA  . GLU A 1 213 ? -19.238 2.667   5.210   1.0 97.38 ? 213 GLU A CA  1 O43570 UNP 213 E 
ATOM 1660 C C   . GLU A 1 213 ? -18.405 3.126   6.417   1.0 97.38 ? 213 GLU A C   1 O43570 UNP 213 E 
ATOM 1661 C CB  . GLU A 1 213 ? -20.191 1.546   5.650   1.0 97.38 ? 213 GLU A CB  1 O43570 UNP 213 E 
ATOM 1662 O O   . GLU A 1 213 ? -17.364 2.547   6.728   1.0 97.38 ? 213 GLU A O   1 O43570 UNP 213 E 
ATOM 1663 C CG  . GLU A 1 213 ? -21.220 1.174   4.572   1.0 97.38 ? 213 GLU A CG  1 O43570 UNP 213 E 
ATOM 1664 C CD  . GLU A 1 213 ? -22.133 2.352   4.206   1.0 97.38 ? 213 GLU A CD  1 O43570 UNP 213 E 
ATOM 1665 O OE1 . GLU A 1 213 ? -22.487 2.466   3.015   1.0 97.38 ? 213 GLU A OE1 1 O43570 UNP 213 E 
ATOM 1666 O OE2 . GLU A 1 213 ? -22.482 3.111   5.142   1.0 97.38 ? 213 GLU A OE2 1 O43570 UNP 213 E 
ATOM 1667 N N   . ARG A 1 214 ? -18.913 4.128   7.148   1.0 97.62 ? 214 ARG A N   1 O43570 UNP 214 R 
ATOM 1668 C CA  . ARG A 1 214 ? -18.289 4.674   8.371   1.0 97.62 ? 214 ARG A CA  1 O43570 UNP 214 R 
ATOM 1669 C C   . ARG A 1 214 ? -16.822 5.075   8.171   1.0 97.62 ? 214 ARG A C   1 O43570 UNP 214 R 
ATOM 1670 C CB  . ARG A 1 214 ? -18.458 3.707   9.558   1.0 97.62 ? 214 ARG A CB  1 O43570 UNP 214 R 
ATOM 1671 O O   . ARG A 1 214 ? -15.948 4.690   8.941   1.0 97.62 ? 214 ARG A O   1 O43570 UNP 214 R 
ATOM 1672 C CG  . ARG A 1 214 ? -19.927 3.397   9.877   1.0 97.62 ? 214 ARG A CG  1 O43570 UNP 214 R 
ATOM 1673 C CD  . ARG A 1 214 ? -20.053 2.520   11.130  1.0 97.62 ? 214 ARG A CD  1 O43570 UNP 214 R 
ATOM 1674 N NE  . ARG A 1 214 ? -19.361 1.235   10.963  1.0 97.62 ? 214 ARG A NE  1 O43570 UNP 214 R 
ATOM 1675 N NH1 . ARG A 1 214 ? -20.987 0.152   9.745   1.0 97.62 ? 214 ARG A NH1 1 O43570 UNP 214 R 
ATOM 1676 N NH2 . ARG A 1 214 ? -18.981 -0.766  9.998   1.0 97.62 ? 214 ARG A NH2 1 O43570 UNP 214 R 
ATOM 1677 C CZ  . ARG A 1 214 ? -19.785 0.212   10.249  1.0 97.62 ? 214 ARG A CZ  1 O43570 UNP 214 R 
ATOM 1678 N N   . THR A 1 215 ? -16.567 5.959   7.209   1.0 98.54 ? 215 THR A N   1 O43570 UNP 215 T 
ATOM 1679 C CA  . THR A 1 215 ? -15.246 6.572   6.954   1.0 98.54 ? 215 THR A CA  1 O43570 UNP 215 T 
ATOM 1680 C C   . THR A 1 215 ? -14.628 7.300   8.158   1.0 98.54 ? 215 THR A C   1 O43570 UNP 215 T 
ATOM 1681 C CB  . THR A 1 215 ? -15.342 7.575   5.798   1.0 98.54 ? 215 THR A CB  1 O43570 UNP 215 T 
ATOM 1682 O O   . THR A 1 215 ? -13.433 7.586   8.153   1.0 98.54 ? 215 THR A O   1 O43570 UNP 215 T 
ATOM 1683 C CG2 . THR A 1 215 ? -15.686 6.903   4.474   1.0 98.54 ? 215 THR A CG2 1 O43570 UNP 215 T 
ATOM 1684 O OG1 . THR A 1 215 ? -16.362 8.507   6.084   1.0 98.54 ? 215 THR A OG1 1 O43570 UNP 215 T 
ATOM 1685 N N   . ALA A 1 216 ? -15.404 7.569   9.214   1.0 98.23 ? 216 ALA A N   1 O43570 UNP 216 A 
ATOM 1686 C CA  . ALA A 1 216 ? -14.901 8.037   10.504  1.0 98.23 ? 216 ALA A CA  1 O43570 UNP 216 A 
ATOM 1687 C C   . ALA A 1 216 ? -14.061 6.982   11.256  1.0 98.23 ? 216 ALA A C   1 O43570 UNP 216 A 
ATOM 1688 C CB  . ALA A 1 216 ? -16.098 8.491   11.347  1.0 98.23 ? 216 ALA A CB  1 O43570 UNP 216 A 
ATOM 1689 O O   . ALA A 1 216 ? -13.308 7.356   12.149  1.0 98.23 ? 216 ALA A O   1 O43570 UNP 216 A 
ATOM 1690 N N   . GLU A 1 217 ? -14.165 5.692   10.914  1.0 98.49 ? 217 GLU A N   1 O43570 UNP 217 E 
ATOM 1691 C CA  . GLU A 1 217 ? -13.404 4.581   11.499  1.0 98.49 ? 217 GLU A CA  1 O43570 UNP 217 E 
ATOM 1692 C C   . GLU A 1 217 ? -12.189 4.239   10.617  1.0 98.49 ? 217 GLU A C   1 O43570 UNP 217 E 
ATOM 1693 C CB  . GLU A 1 217 ? -14.302 3.335   11.675  1.0 98.49 ? 217 GLU A CB  1 O43570 UNP 217 E 
ATOM 1694 O O   . GLU A 1 217 ? -12.317 3.614   9.562   1.0 98.49 ? 217 GLU A O   1 O43570 UNP 217 E 
ATOM 1695 C CG  . GLU A 1 217 ? -15.527 3.539   12.583  1.0 98.49 ? 217 GLU A CG  1 O43570 UNP 217 E 
ATOM 1696 C CD  . GLU A 1 217 ? -16.448 2.302   12.681  1.0 98.49 ? 217 GLU A CD  1 O43570 UNP 217 E 
ATOM 1697 O OE1 . GLU A 1 217 ? -17.590 2.458   13.162  1.0 98.49 ? 217 GLU A OE1 1 O43570 UNP 217 E 
ATOM 1698 O OE2 . GLU A 1 217 ? -16.063 1.163   12.320  1.0 98.49 ? 217 GLU A OE2 1 O43570 UNP 217 E 
ATOM 1699 N N   . TYR A 1 218 ? -10.984 4.624   11.039  1.0 98.75 ? 218 TYR A N   1 O43570 UNP 218 Y 
ATOM 1700 C CA  . TYR A 1 218 ? -9.759  4.404   10.277  1.0 98.75 ? 218 TYR A CA  1 O43570 UNP 218 Y 
ATOM 1701 C C   . TYR A 1 218 ? -8.521  4.206   11.160  1.0 98.75 ? 218 TYR A C   1 O43570 UNP 218 Y 
ATOM 1702 C CB  . TYR A 1 218 ? -9.561  5.564   9.290   1.0 98.75 ? 218 TYR A CB  1 O43570 UNP 218 Y 
ATOM 1703 O O   . TYR A 1 218 ? -8.456  4.632   12.316  1.0 98.75 ? 218 TYR A O   1 O43570 UNP 218 Y 
ATOM 1704 C CG  . TYR A 1 218 ? -9.419  6.939   9.920   1.0 98.75 ? 218 TYR A CG  1 O43570 UNP 218 Y 
ATOM 1705 C CD1 . TYR A 1 218 ? -10.522 7.814   9.977   1.0 98.75 ? 218 TYR A CD1 1 O43570 UNP 218 Y 
ATOM 1706 C CD2 . TYR A 1 218 ? -8.175  7.353   10.433  1.0 98.75 ? 218 TYR A CD2 1 O43570 UNP 218 Y 
ATOM 1707 C CE1 . TYR A 1 218 ? -10.380 9.111   10.510  1.0 98.75 ? 218 TYR A CE1 1 O43570 UNP 218 Y 
ATOM 1708 C CE2 . TYR A 1 218 ? -8.030  8.644   10.969  1.0 98.75 ? 218 TYR A CE2 1 O43570 UNP 218 Y 
ATOM 1709 O OH  . TYR A 1 218 ? -8.920  10.800  11.435  1.0 98.75 ? 218 TYR A OH  1 O43570 UNP 218 Y 
ATOM 1710 C CZ  . TYR A 1 218 ? -9.123  9.532   10.991  1.0 98.75 ? 218 TYR A CZ  1 O43570 UNP 218 Y 
ATOM 1711 N N   . TYR A 1 219 ? -7.521  3.557   10.573  1.0 98.78 ? 219 TYR A N   1 O43570 UNP 219 Y 
ATOM 1712 C CA  . TYR A 1 219 ? -6.157  3.420   11.067  1.0 98.78 ? 219 TYR A CA  1 O43570 UNP 219 Y 
ATOM 1713 C C   . TYR A 1 219 ? -5.281  4.533   10.489  1.0 98.78 ? 219 TYR A C   1 O43570 UNP 219 Y 
ATOM 1714 C CB  . TYR A 1 219 ? -5.595  2.062   10.640  1.0 98.78 ? 219 TYR A CB  1 O43570 UNP 219 Y 
ATOM 1715 O O   . TYR A 1 219 ? -5.429  4.910   9.326   1.0 98.78 ? 219 TYR A O   1 O43570 UNP 219 Y 
ATOM 1716 C CG  . TYR A 1 219 ? -6.434  0.866   11.038  1.0 98.78 ? 219 TYR A CG  1 O43570 UNP 219 Y 
ATOM 1717 C CD1 . TYR A 1 219 ? -6.229  0.256   12.286  1.0 98.78 ? 219 TYR A CD1 1 O43570 UNP 219 Y 
ATOM 1718 C CD2 . TYR A 1 219 ? -7.376  0.325   10.141  1.0 98.78 ? 219 TYR A CD2 1 O43570 UNP 219 Y 
ATOM 1719 C CE1 . TYR A 1 219 ? -6.975  -0.881  12.643  1.0 98.78 ? 219 TYR A CE1 1 O43570 UNP 219 Y 
ATOM 1720 C CE2 . TYR A 1 219 ? -8.123  -0.810  10.498  1.0 98.78 ? 219 TYR A CE2 1 O43570 UNP 219 Y 
ATOM 1721 O OH  . TYR A 1 219 ? -8.673  -2.491  12.112  1.0 98.78 ? 219 TYR A OH  1 O43570 UNP 219 Y 
ATOM 1722 C CZ  . TYR A 1 219 ? -7.934  -1.409  11.754  1.0 98.78 ? 219 TYR A CZ  1 O43570 UNP 219 Y 
ATOM 1723 N N   . ARG A 1 220 ? -4.333  5.041   11.277  1.0 98.79 ? 220 ARG A N   1 O43570 UNP 220 R 
ATOM 1724 C CA  . ARG A 1 220 ? -3.451  6.153   10.919  1.0 98.79 ? 220 ARG A CA  1 O43570 UNP 220 R 
ATOM 1725 C C   . ARG A 1 220 ? -2.011  5.851   11.307  1.0 98.79 ? 220 ARG A C   1 O43570 UNP 220 R 
ATOM 1726 C CB  . ARG A 1 220 ? -3.980  7.420   11.606  1.0 98.79 ? 220 ARG A CB  1 O43570 UNP 220 R 
ATOM 1727 O O   . ARG A 1 220 ? -1.715  5.591   12.471  1.0 98.79 ? 220 ARG A O   1 O43570 UNP 220 R 
ATOM 1728 C CG  . ARG A 1 220 ? -3.131  8.681   11.389  1.0 98.79 ? 220 ARG A CG  1 O43570 UNP 220 R 
ATOM 1729 C CD  . ARG A 1 220 ? -3.052  9.170   9.937   1.0 98.79 ? 220 ARG A CD  1 O43570 UNP 220 R 
ATOM 1730 N NE  . ARG A 1 220 ? -4.366  9.442   9.330   1.0 98.79 ? 220 ARG A NE  1 O43570 UNP 220 R 
ATOM 1731 N NH1 . ARG A 1 220 ? -4.863  11.377  10.481  1.0 98.79 ? 220 ARG A NH1 1 O43570 UNP 220 R 
ATOM 1732 N NH2 . ARG A 1 220 ? -6.311  10.551  9.006   1.0 98.79 ? 220 ARG A NH2 1 O43570 UNP 220 R 
ATOM 1733 C CZ  . ARG A 1 220 ? -5.166  10.456  9.608   1.0 98.79 ? 220 ARG A CZ  1 O43570 UNP 220 R 
ATOM 1734 N N   . TYR A 1 221 ? -1.096  5.962   10.347  1.0 98.69 ? 221 TYR A N   1 O43570 UNP 221 Y 
ATOM 1735 C CA  . TYR A 1 221 ? 0.341   5.867   10.611  1.0 98.69 ? 221 TYR A CA  1 O43570 UNP 221 Y 
ATOM 1736 C C   . TYR A 1 221 ? 1.170   6.624   9.559   1.0 98.69 ? 221 TYR A C   1 O43570 UNP 221 Y 
ATOM 1737 C CB  . TYR A 1 221 ? 0.753   4.389   10.734  1.0 98.69 ? 221 TYR A CB  1 O43570 UNP 221 Y 
ATOM 1738 O O   . TYR A 1 221 ? 0.692   6.950   8.473   1.0 98.69 ? 221 TYR A O   1 O43570 UNP 221 Y 
ATOM 1739 C CG  . TYR A 1 221 ? 0.877   3.638   9.423   1.0 98.69 ? 221 TYR A CG  1 O43570 UNP 221 Y 
ATOM 1740 C CD1 . TYR A 1 221 ? -0.261  3.132   8.763   1.0 98.69 ? 221 TYR A CD1 1 O43570 UNP 221 Y 
ATOM 1741 C CD2 . TYR A 1 221 ? 2.155   3.430   8.877   1.0 98.69 ? 221 TYR A CD2 1 O43570 UNP 221 Y 
ATOM 1742 C CE1 . TYR A 1 221 ? -0.116  2.437   7.544   1.0 98.69 ? 221 TYR A CE1 1 O43570 UNP 221 Y 
ATOM 1743 C CE2 . TYR A 1 221 ? 2.304   2.742   7.662   1.0 98.69 ? 221 TYR A CE2 1 O43570 UNP 221 Y 
ATOM 1744 O OH  . TYR A 1 221 ? 1.351   1.598   5.815   1.0 98.69 ? 221 TYR A OH  1 O43570 UNP 221 Y 
ATOM 1745 C CZ  . TYR A 1 221 ? 1.169   2.252   6.989   1.0 98.69 ? 221 TYR A CZ  1 O43570 UNP 221 Y 
ATOM 1746 N N   . ARG A 1 222 ? 2.428   6.941   9.883   1.0 98.38 ? 222 ARG A N   1 O43570 UNP 222 R 
ATOM 1747 C CA  . ARG A 1 222 ? 3.405   7.505   8.930   1.0 98.38 ? 222 ARG A CA  1 O43570 UNP 222 R 
ATOM 1748 C C   . ARG A 1 222 ? 4.140   6.366   8.232   1.0 98.38 ? 222 ARG A C   1 O43570 UNP 222 R 
ATOM 1749 C CB  . ARG A 1 222 ? 4.404   8.413   9.668   1.0 98.38 ? 222 ARG A CB  1 O43570 UNP 222 R 
ATOM 1750 O O   . ARG A 1 222 ? 4.726   5.542   8.914   1.0 98.38 ? 222 ARG A O   1 O43570 UNP 222 R 
ATOM 1751 C CG  . ARG A 1 222 ? 3.804   9.718   10.215  1.0 98.38 ? 222 ARG A CG  1 O43570 UNP 222 R 
ATOM 1752 C CD  . ARG A 1 222 ? 3.529   10.751  9.111   1.0 98.38 ? 222 ARG A CD  1 O43570 UNP 222 R 
ATOM 1753 N NE  . ARG A 1 222 ? 3.092   12.042  9.690   1.0 98.38 ? 222 ARG A NE  1 O43570 UNP 222 R 
ATOM 1754 N NH1 . ARG A 1 222 ? 2.846   13.261  7.747   1.0 98.38 ? 222 ARG A NH1 1 O43570 UNP 222 R 
ATOM 1755 N NH2 . ARG A 1 222 ? 2.585   14.262  9.713   1.0 98.38 ? 222 ARG A NH2 1 O43570 UNP 222 R 
ATOM 1756 C CZ  . ARG A 1 222 ? 2.844   13.174  9.047   1.0 98.38 ? 222 ARG A CZ  1 O43570 UNP 222 R 
ATOM 1757 N N   . GLY A 1 223 ? 4.156   6.300   6.915   1.0 98.41 ? 223 GLY A N   1 O43570 UNP 223 G 
ATOM 1758 C CA  . GLY A 1 223 ? 4.767   5.200   6.175   1.0 98.41 ? 223 GLY A CA  1 O43570 UNP 223 G 
ATOM 1759 C C   . GLY A 1 223 ? 5.432   5.657   4.887   1.0 98.41 ? 223 GLY A C   1 O43570 UNP 223 G 
ATOM 1760 O O   . GLY A 1 223 ? 5.832   6.818   4.750   1.0 98.41 ? 223 GLY A O   1 O43570 UNP 223 G 
ATOM 1761 N N   . SER A 1 224 ? 5.532   4.737   3.934   1.0 98.53 ? 224 SER A N   1 O43570 UNP 224 S 
ATOM 1762 C CA  . SER A 1 224 ? 6.169   4.971   2.644   1.0 98.53 ? 224 SER A CA  1 O43570 UNP 224 S 
ATOM 1763 C C   . SER A 1 224 ? 5.221   4.726   1.483   1.0 98.53 ? 224 SER A C   1 O43570 UNP 224 S 
ATOM 1764 C CB  . SER A 1 224 ? 7.437   4.114   2.502   1.0 98.53 ? 224 SER A CB  1 O43570 UNP 224 S 
ATOM 1765 O O   . SER A 1 224 ? 4.139   4.172   1.655   1.0 98.53 ? 224 SER A O   1 O43570 UNP 224 S 
ATOM 1766 O OG  . SER A 1 224 ? 7.141   2.744   2.287   1.0 98.53 ? 224 SER A OG  1 O43570 UNP 224 S 
ATOM 1767 N N   . LEU A 1 225 ? 5.664   5.079   0.276   1.0 98.21 ? 225 LEU A N   1 O43570 UNP 225 L 
ATOM 1768 C CA  . LEU A 1 225 ? 5.148   4.426   -0.926  1.0 98.21 ? 225 LEU A CA  1 O43570 UNP 225 L 
ATOM 1769 C C   . LEU A 1 225 ? 5.388   2.910   -0.819  1.0 98.21 ? 225 LEU A C   1 O43570 UNP 225 L 
ATOM 1770 C CB  . LEU A 1 225 ? 5.834   5.001   -2.176  1.0 98.21 ? 225 LEU A CB  1 O43570 UNP 225 L 
ATOM 1771 O O   . LEU A 1 225 ? 6.455   2.482   -0.366  1.0 98.21 ? 225 LEU A O   1 O43570 UNP 225 L 
ATOM 1772 C CG  . LEU A 1 225 ? 5.426   6.455   -2.488  1.0 98.21 ? 225 LEU A CG  1 O43570 UNP 225 L 
ATOM 1773 C CD1 . LEU A 1 225 ? 6.666   7.333   -2.652  1.0 98.21 ? 225 LEU A CD1 1 O43570 UNP 225 L 
ATOM 1774 C CD2 . LEU A 1 225 ? 4.598   6.534   -3.769  1.0 98.21 ? 225 LEU A CD2 1 O43570 UNP 225 L 
ATOM 1775 N N   . THR A 1 226 ? 4.417   2.114   -1.255  1.0 98.54 ? 226 THR A N   1 O43570 UNP 226 T 
ATOM 1776 C CA  . THR A 1 226 ? 4.505   0.644   -1.353  1.0 98.54 ? 226 THR A CA  1 O43570 UNP 226 T 
ATOM 1777 C C   . THR A 1 226 ? 5.154   0.181   -2.658  1.0 98.54 ? 226 THR A C   1 O43570 UNP 226 T 
ATOM 1778 C CB  . THR A 1 226 ? 3.110   0.032   -1.251  1.0 98.54 ? 226 THR A CB  1 O43570 UNP 226 T 
ATOM 1779 O O   . THR A 1 226 ? 5.386   -1.002  -2.872  1.0 98.54 ? 226 THR A O   1 O43570 UNP 226 T 
ATOM 1780 C CG2 . THR A 1 226 ? 2.445   0.384   0.080   1.0 98.54 ? 226 THR A CG2 1 O43570 UNP 226 T 
ATOM 1781 O OG1 . THR A 1 226 ? 2.335   0.586   -2.283  1.0 98.54 ? 226 THR A OG1 1 O43570 UNP 226 T 
ATOM 1782 N N   . THR A 1 227 ? 5.516   1.130   -3.520  1.0 97.71 ? 227 THR A N   1 O43570 UNP 227 T 
ATOM 1783 C CA  . THR A 1 227 ? 6.212   0.904   -4.784  1.0 97.71 ? 227 THR A CA  1 O43570 UNP 227 T 
ATOM 1784 C C   . THR A 1 227 ? 7.488   1.739   -4.847  1.0 97.71 ? 227 THR A C   1 O43570 UNP 227 T 
ATOM 1785 C CB  . THR A 1 227 ? 5.310   1.236   -5.979  1.0 97.71 ? 227 THR A CB  1 O43570 UNP 227 T 
ATOM 1786 O O   . THR A 1 227 ? 7.592   2.780   -4.182  1.0 97.71 ? 227 THR A O   1 O43570 UNP 227 T 
ATOM 1787 C CG2 . THR A 1 227 ? 4.095   0.320   -6.036  1.0 97.71 ? 227 THR A CG2 1 O43570 UNP 227 T 
ATOM 1788 O OG1 . THR A 1 227 ? 4.820   2.553   -5.902  1.0 97.71 ? 227 THR A OG1 1 O43570 UNP 227 T 
ATOM 1789 N N   . PRO A 1 228 ? 8.487   1.334   -5.648  1.0 97.61 ? 228 PRO A N   1 O43570 UNP 228 P 
ATOM 1790 C CA  . PRO A 1 228 ? 9.661   2.153   -5.901  1.0 97.61 ? 228 PRO A CA  1 O43570 UNP 228 P 
ATOM 1791 C C   . PRO A 1 228 ? 9.293   3.570   -6.370  1.0 97.61 ? 228 PRO A C   1 O43570 UNP 228 P 
ATOM 1792 C CB  . PRO A 1 228 ? 10.451  1.388   -6.953  1.0 97.61 ? 228 PRO A CB  1 O43570 UNP 228 P 
ATOM 1793 O O   . PRO A 1 228 ? 8.491   3.716   -7.294  1.0 97.61 ? 228 PRO A O   1 O43570 UNP 228 P 
ATOM 1794 C CG  . PRO A 1 228 ? 10.119  -0.062  -6.619  1.0 97.61 ? 228 PRO A CG  1 O43570 UNP 228 P 
ATOM 1795 C CD  . PRO A 1 228 ? 8.634   0.036   -6.291  1.0 97.61 ? 228 PRO A CD  1 O43570 UNP 228 P 
ATOM 1796 N N   . PRO A 1 229 ? 9.891   4.626   -5.786  1.0 97.16 ? 229 PRO A N   1 O43570 UNP 229 P 
ATOM 1797 C CA  . PRO A 1 229 ? 11.129  4.622   -4.997  1.0 97.16 ? 229 PRO A CA  1 O43570 UNP 229 P 
ATOM 1798 C C   . PRO A 1 229 ? 10.978  4.407   -3.475  1.0 97.16 ? 229 PRO A C   1 O43570 UNP 229 P 
ATOM 1799 C CB  . PRO A 1 229 ? 11.769  5.980   -5.315  1.0 97.16 ? 229 PRO A CB  1 O43570 UNP 229 P 
ATOM 1800 O O   . PRO A 1 229 ? 11.957  4.605   -2.765  1.0 97.16 ? 229 PRO A O   1 O43570 UNP 229 P 
ATOM 1801 C CG  . PRO A 1 229 ? 10.533  6.865   -5.404  1.0 97.16 ? 229 PRO A CG  1 O43570 UNP 229 P 
ATOM 1802 C CD  . PRO A 1 229 ? 9.542   5.990   -6.151  1.0 97.16 ? 229 PRO A CD  1 O43570 UNP 229 P 
ATOM 1803 N N   . CYS A 1 230 ? 9.809   4.015   -2.960  1.0 98.07 ? 230 CYS A N   1 O43570 UNP 230 C 
ATOM 1804 C CA  . CYS A 1 230 ? 9.557   3.708   -1.543  1.0 98.07 ? 230 CYS A CA  1 O43570 UNP 230 C 
ATOM 1805 C C   . CYS A 1 230 ? 9.893   4.849   -0.561  1.0 98.07 ? 230 CYS A C   1 O43570 UNP 230 C 
ATOM 1806 C CB  . CYS A 1 230 ? 10.240  2.401   -1.135  1.0 98.07 ? 230 CYS A CB  1 O43570 UNP 230 C 
ATOM 1807 O O   . CYS A 1 230 ? 10.382  4.604   0.548   1.0 98.07 ? 230 CYS A O   1 O43570 UNP 230 C 
ATOM 1808 S SG  . CYS A 1 230 ? 10.089  0.977   -2.242  1.0 98.07 ? 230 CYS A SG  1 O43570 UNP 230 C 
ATOM 1809 N N   . ASN A 1 231 ? 9.686   6.110   -0.962  1.0 97.83 ? 231 ASN A N   1 O43570 UNP 231 N 
ATOM 1810 C CA  . ASN A 1 231 ? 9.994   7.248   -0.094  1.0 97.83 ? 231 ASN A CA  1 O43570 UNP 231 N 
ATOM 1811 C C   . ASN A 1 231 ? 9.122   7.216   1.180   1.0 97.83 ? 231 ASN A C   1 O43570 UNP 231 N 
ATOM 1812 C CB  . ASN A 1 231 ? 9.818   8.592   -0.822  1.0 97.83 ? 231 ASN A CB  1 O43570 UNP 231 N 
ATOM 1813 O O   . ASN A 1 231 ? 7.914   7.008   1.059   1.0 97.83 ? 231 ASN A O   1 O43570 UNP 231 N 
ATOM 1814 C CG  . ASN A 1 231 ? 10.693  8.770   -2.041  1.0 97.83 ? 231 ASN A CG  1 O43570 UNP 231 N 
ATOM 1815 N ND2 . ASN A 1 231 ? 11.996  8.732   -1.895  1.0 97.83 ? 231 ASN A ND2 1 O43570 UNP 231 N 
ATOM 1816 O OD1 . ASN A 1 231 ? 10.232  8.967   -3.147  1.0 97.83 ? 231 ASN A OD1 1 O43570 UNP 231 N 
ATOM 1817 N N   . PRO A 1 232 ? 9.701   7.441   2.377   1.0 97.85 ? 232 PRO A N   1 O43570 UNP 232 P 
ATOM 1818 C CA  . PRO A 1 232 ? 8.990   7.429   3.660   1.0 97.85 ? 232 PRO A CA  1 O43570 UNP 232 P 
ATOM 1819 C C   . PRO A 1 232 ? 8.246   8.752   3.921   1.0 97.85 ? 232 PRO A C   1 O43570 UNP 232 P 
ATOM 1820 C CB  . PRO A 1 232 ? 10.077  7.121   4.692   1.0 97.85 ? 232 PRO A CB  1 O43570 UNP 232 P 
ATOM 1821 O O   . PRO A 1 232 ? 8.572   9.504   4.838   1.0 97.85 ? 232 PRO A O   1 O43570 UNP 232 P 
ATOM 1822 C CG  . PRO A 1 232 ? 11.304  7.816   4.113   1.0 97.85 ? 232 PRO A CG  1 O43570 UNP 232 P 
ATOM 1823 C CD  . PRO A 1 232 ? 11.134  7.592   2.613   1.0 97.85 ? 232 PRO A CD  1 O43570 UNP 232 P 
ATOM 1824 N N   . THR A 1 233 ? 7.298   9.084   3.047   1.0 98.17 ? 233 THR A N   1 O43570 UNP 233 T 
ATOM 1825 C CA  . THR A 1 233 ? 6.671   10.416  2.954   1.0 98.17 ? 233 THR A CA  1 O43570 UNP 233 T 
ATOM 1826 C C   . THR A 1 233 ? 5.147   10.375  3.014   1.0 98.17 ? 233 THR A C   1 O43570 UNP 233 T 
ATOM 1827 C CB  . THR A 1 233 ? 7.123   11.117  1.665   1.0 98.17 ? 233 THR A CB  1 O43570 UNP 233 T 
ATOM 1828 O O   . THR A 1 233 ? 4.500   11.405  2.816   1.0 98.17 ? 233 THR A O   1 O43570 UNP 233 T 
ATOM 1829 C CG2 . THR A 1 233 ? 8.626   11.396  1.691   1.0 98.17 ? 233 THR A CG2 1 O43570 UNP 233 T 
ATOM 1830 O OG1 . THR A 1 233 ? 6.870   10.272  0.566   1.0 98.17 ? 233 THR A OG1 1 O43570 UNP 233 T 
ATOM 1831 N N   . VAL A 1 234 ? 4.566   9.204   3.293   1.0 98.70 ? 234 VAL A N   1 O43570 UNP 234 V 
ATOM 1832 C CA  . VAL A 1 234 ? 3.121   8.976   3.214   1.0 98.70 ? 234 VAL A CA  1 O43570 UNP 234 V 
ATOM 1833 C C   . VAL A 1 234 ? 2.487   9.036   4.600   1.0 98.70 ? 234 VAL A C   1 O43570 UNP 234 V 
ATOM 1834 C CB  . VAL A 1 234 ? 2.801   7.650   2.496   1.0 98.70 ? 234 VAL A CB  1 O43570 UNP 234 V 
ATOM 1835 O O   . VAL A 1 234 ? 2.889   8.324   5.517   1.0 98.70 ? 234 VAL A O   1 O43570 UNP 234 V 
ATOM 1836 C CG1 . VAL A 1 234 ? 1.284   7.480   2.367   1.0 98.70 ? 234 VAL A CG1 1 O43570 UNP 234 V 
ATOM 1837 C CG2 . VAL A 1 234 ? 3.397   7.609   1.080   1.0 98.70 ? 234 VAL A CG2 1 O43570 UNP 234 V 
ATOM 1838 N N   . LEU A 1 235 ? 1.460   9.866   4.764   1.0 98.76 ? 235 LEU A N   1 O43570 UNP 235 L 
ATOM 1839 C CA  . LEU A 1 235 ? 0.502   9.750   5.859   1.0 98.76 ? 235 LEU A CA  1 O43570 UNP 235 L 
ATOM 1840 C C   . LEU A 1 235 ? -0.612  8.787   5.437   1.0 98.76 ? 235 LEU A C   1 O43570 UNP 235 L 
ATOM 1841 C CB  . LEU A 1 235 ? -0.029  11.147  6.214   1.0 98.76 ? 235 LEU A CB  1 O43570 UNP 235 L 
ATOM 1842 O O   . LEU A 1 235 ? -1.462  9.131   4.616   1.0 98.76 ? 235 LEU A O   1 O43570 UNP 235 L 
ATOM 1843 C CG  . LEU A 1 235 ? -0.933  11.158  7.461   1.0 98.76 ? 235 LEU A CG  1 O43570 UNP 235 L 
ATOM 1844 C CD1 . LEU A 1 235 ? -0.161  10.723  8.709   1.0 98.76 ? 235 LEU A CD1 1 O43570 UNP 235 L 
ATOM 1845 C CD2 . LEU A 1 235 ? -1.443  12.576  7.703   1.0 98.76 ? 235 LEU A CD2 1 O43570 UNP 235 L 
ATOM 1846 N N   . TRP A 1 236 ? -0.596  7.579   5.985   1.0 98.87 ? 236 TRP A N   1 O43570 UNP 236 W 
ATOM 1847 C CA  . TRP A 1 236 ? -1.568  6.545   5.651   1.0 98.87 ? 236 TRP A CA  1 O43570 UNP 236 W 
ATOM 1848 C C   . TRP A 1 236 ? -2.851  6.712   6.449   1.0 98.87 ? 236 TRP A C   1 O43570 UNP 236 W 
ATOM 1849 C CB  . TRP A 1 236 ? -0.958  5.167   5.891   1.0 98.87 ? 236 TRP A CB  1 O43570 UNP 236 W 
ATOM 1850 O O   . TRP A 1 236 ? -2.810  6.869   7.669   1.0 98.87 ? 236 TRP A O   1 O43570 UNP 236 W 
ATOM 1851 C CG  . TRP A 1 236 ? -0.020  4.750   4.814   1.0 98.87 ? 236 TRP A CG  1 O43570 UNP 236 W 
ATOM 1852 C CD1 . TRP A 1 236 ? 1.327   4.842   4.843   1.0 98.87 ? 236 TRP A CD1 1 O43570 UNP 236 W 
ATOM 1853 C CD2 . TRP A 1 236 ? -0.366  4.202   3.509   1.0 98.87 ? 236 TRP A CD2 1 O43570 UNP 236 W 
ATOM 1854 C CE2 . TRP A 1 236 ? 0.844   3.998   2.786   1.0 98.87 ? 236 TRP A CE2 1 O43570 UNP 236 W 
ATOM 1855 C CE3 . TRP A 1 236 ? -1.575  3.874   2.857   1.0 98.87 ? 236 TRP A CE3 1 O43570 UNP 236 W 
ATOM 1856 N NE1 . TRP A 1 236 ? 1.842   4.385   3.645   1.0 98.87 ? 236 TRP A NE1 1 O43570 UNP 236 W 
ATOM 1857 C CH2 . TRP A 1 236 ? -0.348  3.212   0.849   1.0 98.87 ? 236 TRP A CH2 1 O43570 UNP 236 W 
ATOM 1858 C CZ2 . TRP A 1 236 ? 0.864   3.523   1.475   1.0 98.87 ? 236 TRP A CZ2 1 O43570 UNP 236 W 
ATOM 1859 C CZ3 . TRP A 1 236 ? -1.560  3.373   1.541   1.0 98.87 ? 236 TRP A CZ3 1 O43570 UNP 236 W 
ATOM 1860 N N   . THR A 1 237 ? -3.985  6.624   5.761   1.0 98.93 ? 237 THR A N   1 O43570 UNP 237 T 
ATOM 1861 C CA  . THR A 1 237 ? -5.298  6.393   6.364   1.0 98.93 ? 237 THR A CA  1 O43570 UNP 237 T 
ATOM 1862 C C   . THR A 1 237 ? -5.873  5.124   5.754   1.0 98.93 ? 237 THR A C   1 O43570 UNP 237 T 
ATOM 1863 C CB  . THR A 1 237 ? -6.233  7.585   6.139   1.0 98.93 ? 237 THR A CB  1 O43570 UNP 237 T 
ATOM 1864 O O   . THR A 1 237 ? -6.266  5.137   4.594   1.0 98.93 ? 237 THR A O   1 O43570 UNP 237 T 
ATOM 1865 C CG2 . THR A 1 237 ? -7.591  7.393   6.802   1.0 98.93 ? 237 THR A CG2 1 O43570 UNP 237 T 
ATOM 1866 O OG1 . THR A 1 237 ? -5.647  8.749   6.696   1.0 98.93 ? 237 THR A OG1 1 O43570 UNP 237 T 
ATOM 1867 N N   . VAL A 1 238 ? -5.898  4.032   6.515   1.0 98.92 ? 238 VAL A N   1 O43570 UNP 238 V 
ATOM 1868 C CA  . VAL A 1 238 ? -6.520  2.771   6.081   1.0 98.92 ? 238 VAL A CA  1 O43570 UNP 238 V 
ATOM 1869 C C   . VAL A 1 238 ? -7.894  2.704   6.724   1.0 98.92 ? 238 VAL A C   1 O43570 UNP 238 V 
ATOM 1870 C CB  . VAL A 1 238 ? -5.665  1.534   6.432   1.0 98.92 ? 238 VAL A CB  1 O43570 UNP 238 V 
ATOM 1871 O O   . VAL A 1 238 ? -7.992  2.760   7.949   1.0 98.92 ? 238 VAL A O   1 O43570 UNP 238 V 
ATOM 1872 C CG1 . VAL A 1 238 ? -6.231  0.279   5.759   1.0 98.92 ? 238 VAL A CG1 1 O43570 UNP 238 V 
ATOM 1873 C CG2 . VAL A 1 238 ? -4.189  1.691   6.033   1.0 98.92 ? 238 VAL A CG2 1 O43570 UNP 238 V 
ATOM 1874 N N   . PHE A 1 239 ? -8.963  2.647   5.938   1.0 98.87 ? 239 PHE A N   1 O43570 UNP 239 F 
ATOM 1875 C CA  . PHE A 1 239 ? -10.304 2.575   6.515   1.0 98.87 ? 239 PHE A CA  1 O43570 UNP 239 F 
ATOM 1876 C C   . PHE A 1 239 ? -10.536 1.224   7.187   1.0 98.87 ? 239 PHE A C   1 O43570 UNP 239 F 
ATOM 1877 C CB  . PHE A 1 239 ? -11.367 2.871   5.465   1.0 98.87 ? 239 PHE A CB  1 O43570 UNP 239 F 
ATOM 1878 O O   . PHE A 1 239 ? -10.060 0.189   6.723   1.0 98.87 ? 239 PHE A O   1 O43570 UNP 239 F 
ATOM 1879 C CG  . PHE A 1 239 ? -11.321 4.295   4.957   1.0 98.87 ? 239 PHE A CG  1 O43570 UNP 239 F 
ATOM 1880 C CD1 . PHE A 1 239 ? -11.722 5.359   5.787   1.0 98.87 ? 239 PHE A CD1 1 O43570 UNP 239 F 
ATOM 1881 C CD2 . PHE A 1 239 ? -10.863 4.559   3.657   1.0 98.87 ? 239 PHE A CD2 1 O43570 UNP 239 F 
ATOM 1882 C CE1 . PHE A 1 239 ? -11.668 6.682   5.312   1.0 98.87 ? 239 PHE A CE1 1 O43570 UNP 239 F 
ATOM 1883 C CE2 . PHE A 1 239 ? -10.837 5.876   3.173   1.0 98.87 ? 239 PHE A CE2 1 O43570 UNP 239 F 
ATOM 1884 C CZ  . PHE A 1 239 ? -11.236 6.939   3.999   1.0 98.87 ? 239 PHE A CZ  1 O43570 UNP 239 F 
ATOM 1885 N N   . ARG A 1 240 ? -11.271 1.236   8.302   1.0 98.54 ? 240 ARG A N   1 O43570 UNP 240 R 
ATOM 1886 C CA  . ARG A 1 240 ? -11.546 0.023   9.078   1.0 98.54 ? 240 ARG A CA  1 O43570 UNP 240 R 
ATOM 1887 C C   . ARG A 1 240 ? -12.446 -0.945  8.326   1.0 98.54 ? 240 ARG A C   1 O43570 UNP 240 R 
ATOM 1888 C CB  . ARG A 1 240 ? -12.168 0.426   10.417  1.0 98.54 ? 240 ARG A CB  1 O43570 UNP 240 R 
ATOM 1889 O O   . ARG A 1 240 ? -12.291 -2.158  8.450   1.0 98.54 ? 240 ARG A O   1 O43570 UNP 240 R 
ATOM 1890 C CG  . ARG A 1 240 ? -12.407 -0.795  11.310  1.0 98.54 ? 240 ARG A CG  1 O43570 UNP 240 R 
ATOM 1891 C CD  . ARG A 1 240 ? -13.106 -0.372  12.593  1.0 98.54 ? 240 ARG A CD  1 O43570 UNP 240 R 
ATOM 1892 N NE  . ARG A 1 240 ? -13.481 -1.553  13.383  1.0 98.54 ? 240 ARG A NE  1 O43570 UNP 240 R 
ATOM 1893 N NH1 . ARG A 1 240 ? -15.746 -1.505  12.947  1.0 98.54 ? 240 ARG A NH1 1 O43570 UNP 240 R 
ATOM 1894 N NH2 . ARG A 1 240 ? -14.855 -3.216  14.073  1.0 98.54 ? 240 ARG A NH2 1 O43570 UNP 240 R 
ATOM 1895 C CZ  . ARG A 1 240 ? -14.690 -2.076  13.461  1.0 98.54 ? 240 ARG A CZ  1 O43570 UNP 240 R 
ATOM 1896 N N   . ASN A 1 241 ? -13.437 -0.409  7.627   1.0 98.59 ? 241 ASN A N   1 O43570 UNP 241 N 
ATOM 1897 C CA  . ASN A 1 241 ? -14.424 -1.211  6.932   1.0 98.59 ? 241 ASN A CA  1 O43570 UNP 241 N 
ATOM 1898 C C   . ASN A 1 241 ? -13.983 -1.488  5.496   1.0 98.59 ? 241 ASN A C   1 O43570 UNP 241 N 
ATOM 1899 C CB  . ASN A 1 241 ? -15.795 -0.534  7.056   1.0 98.59 ? 241 ASN A CB  1 O43570 UNP 241 N 
ATOM 1900 O O   . ASN A 1 241 ? -13.514 -0.568  4.829   1.0 98.59 ? 241 ASN A O   1 O43570 UNP 241 N 
ATOM 1901 C CG  . ASN A 1 241 ? -16.269 -0.619  8.487   1.0 98.59 ? 241 ASN A CG  1 O43570 UNP 241 N 
ATOM 1902 N ND2 . ASN A 1 241 ? -16.462 -1.818  8.994   1.0 98.59 ? 241 ASN A ND2 1 O43570 UNP 241 N 
ATOM 1903 O OD1 . ASN A 1 241 ? -16.459 0.337   9.212   1.0 98.59 ? 241 ASN A OD1 1 O43570 UNP 241 N 
ATOM 1904 N N   . PRO A 1 242 ? -14.129 -2.733  5.017   1.0 98.74 ? 242 PRO A N   1 O43570 UNP 242 P 
ATOM 1905 C CA  . PRO A 1 242 ? -13.921 -3.025  3.616   1.0 98.74 ? 242 PRO A CA  1 O43570 UNP 242 P 
ATOM 1906 C C   . PRO A 1 242 ? -15.127 -2.572  2.788   1.0 98.74 ? 242 PRO A C   1 O43570 UNP 242 P 
ATOM 1907 C CB  . PRO A 1 242 ? -13.707 -4.538  3.552   1.0 98.74 ? 242 PRO A CB  1 O43570 UNP 242 P 
ATOM 1908 O O   . PRO A 1 242 ? -16.232 -2.384  3.306   1.0 98.74 ? 242 PRO A O   1 O43570 UNP 242 P 
ATOM 1909 C CG  . PRO A 1 242 ? -14.628 -5.040  4.663   1.0 98.74 ? 242 PRO A CG  1 O43570 UNP 242 P 
ATOM 1910 C CD  . PRO A 1 242 ? -14.516 -3.948  5.727   1.0 98.74 ? 242 PRO A CD  1 O43570 UNP 242 P 
ATOM 1911 N N   . VAL A 1 243 ? -14.918 -2.450  1.484   1.0 98.85 ? 243 VAL A N   1 O43570 UNP 243 V 
ATOM 1912 C CA  . VAL A 1 243 ? -16.001 -2.467  0.496   1.0 98.85 ? 243 VAL A CA  1 O43570 UNP 243 V 
ATOM 1913 C C   . VAL A 1 243 ? -16.115 -3.853  -0.118  1.0 98.85 ? 243 VAL A C   1 O43570 UNP 243 V 
ATOM 1914 C CB  . VAL A 1 243 ? -15.805 -1.431  -0.615  1.0 98.85 ? 243 VAL A CB  1 O43570 UNP 243 V 
ATOM 1915 O O   . VAL A 1 243 ? -15.159 -4.627  -0.115  1.0 98.85 ? 243 VAL A O   1 O43570 UNP 243 V 
ATOM 1916 C CG1 . VAL A 1 243 ? -15.802 -0.004  -0.073  1.0 98.85 ? 243 VAL A CG1 1 O43570 UNP 243 V 
ATOM 1917 C CG2 . VAL A 1 243 ? -14.527 -1.703  -1.395  1.0 98.85 ? 243 VAL A CG2 1 O43570 UNP 243 V 
ATOM 1918 N N   . GLN A 1 244 ? -17.270 -4.139  -0.705  1.0 98.84 ? 244 GLN A N   1 O43570 UNP 244 Q 
ATOM 1919 C CA  . GLN A 1 244 ? -17.490 -5.372  -1.449  1.0 98.84 ? 244 GLN A CA  1 O43570 UNP 244 Q 
ATOM 1920 C C   . GLN A 1 244 ? -17.470 -5.107  -2.949  1.0 98.84 ? 244 GLN A C   1 O43570 UNP 244 Q 
ATOM 1921 C CB  . GLN A 1 244 ? -18.798 -6.029  -1.002  1.0 98.84 ? 244 GLN A CB  1 O43570 UNP 244 Q 
ATOM 1922 O O   . GLN A 1 244 ? -17.956 -4.064  -3.389  1.0 98.84 ? 244 GLN A O   1 O43570 UNP 244 Q 
ATOM 1923 C CG  . GLN A 1 244 ? -18.724 -6.385  0.488   1.0 98.84 ? 244 GLN A CG  1 O43570 UNP 244 Q 
ATOM 1924 C CD  . GLN A 1 244 ? -19.872 -7.245  0.979   1.0 98.84 ? 244 GLN A CD  1 O43570 UNP 244 Q 
ATOM 1925 N NE2 . GLN A 1 244 ? -19.727 -7.796  2.163   1.0 98.84 ? 244 GLN A NE2 1 O43570 UNP 244 Q 
ATOM 1926 O OE1 . GLN A 1 244 ? -20.889 -7.443  0.315   1.0 98.84 ? 244 GLN A OE1 1 O43570 UNP 244 Q 
ATOM 1927 N N   . ILE A 1 245 ? -16.946 -6.063  -3.712  1.0 98.84 ? 245 ILE A N   1 O43570 UNP 245 I 
ATOM 1928 C CA  . ILE A 1 245 ? -17.153 -6.202  -5.159  1.0 98.84 ? 245 ILE A CA  1 O43570 UNP 245 I 
ATOM 1929 C C   . ILE A 1 245 ? -17.590 -7.638  -5.463  1.0 98.84 ? 245 ILE A C   1 O43570 UNP 245 I 
ATOM 1930 C CB  . ILE A 1 245 ? -15.907 -5.783  -5.976  1.0 98.84 ? 245 ILE A CB  1 O43570 UNP 245 I 
ATOM 1931 O O   . ILE A 1 245 ? -17.269 -8.562  -4.714  1.0 98.84 ? 245 ILE A O   1 O43570 UNP 245 I 
ATOM 1932 C CG1 . ILE A 1 245 ? -14.695 -6.707  -5.717  1.0 98.84 ? 245 ILE A CG1 1 O43570 UNP 245 I 
ATOM 1933 C CG2 . ILE A 1 245 ? -15.568 -4.303  -5.707  1.0 98.84 ? 245 ILE A CG2 1 O43570 UNP 245 I 
ATOM 1934 C CD1 . ILE A 1 245 ? -13.483 -6.411  -6.610  1.0 98.84 ? 245 ILE A CD1 1 O43570 UNP 245 I 
ATOM 1935 N N   . SER A 1 246 ? -18.321 -7.849  -6.557  1.0 98.77 ? 246 SER A N   1 O43570 UNP 246 S 
ATOM 1936 C CA  . SER A 1 246 ? -18.740 -9.207  -6.946  1.0 98.77 ? 246 SER A CA  1 O43570 UNP 246 S 
ATOM 1937 C C   . SER A 1 246 ? -17.556 -10.098 -7.326  1.0 98.77 ? 246 SER A C   1 O43570 UNP 246 S 
ATOM 1938 C CB  . SER A 1 246 ? -19.756 -9.189  -8.087  1.0 98.77 ? 246 SER A CB  1 O43570 UNP 246 S 
ATOM 1939 O O   . SER A 1 246 ? -16.481 -9.612  -7.685  1.0 98.77 ? 246 SER A O   1 O43570 UNP 246 S 
ATOM 1940 O OG  . SER A 1 246 ? -19.221 -8.503  -9.197  1.0 98.77 ? 246 SER A OG  1 O43570 UNP 246 S 
ATOM 1941 N N   . GLN A 1 247 ? -17.776 -11.414 -7.306  1.0 98.54 ? 247 GLN A N   1 O43570 UNP 247 Q 
ATOM 1942 C CA  . GLN A 1 247 ? -16.800 -12.391 -7.786  1.0 98.54 ? 247 GLN A CA  1 O43570 UNP 247 Q 
ATOM 1943 C C   . GLN A 1 247 ? -16.399 -12.121 -9.245  1.0 98.54 ? 247 GLN A C   1 O43570 UNP 247 Q 
ATOM 1944 C CB  . GLN A 1 247 ? -17.408 -13.792 -7.626  1.0 98.54 ? 247 GLN A CB  1 O43570 UNP 247 Q 
ATOM 1945 O O   . GLN A 1 247 ? -15.221 -12.200 -9.585  1.0 98.54 ? 247 GLN A O   1 O43570 UNP 247 Q 
ATOM 1946 C CG  . GLN A 1 247 ? -16.424 -14.889 -8.054  1.0 98.54 ? 247 GLN A CG  1 O43570 UNP 247 Q 
ATOM 1947 C CD  . GLN A 1 247 ? -16.944 -16.303 -7.817  1.0 98.54 ? 247 GLN A CD  1 O43570 UNP 247 Q 
ATOM 1948 N NE2 . GLN A 1 247 ? -16.244 -17.300 -8.312  1.0 98.54 ? 247 GLN A NE2 1 O43570 UNP 247 Q 
ATOM 1949 O OE1 . GLN A 1 247 ? -17.955 -16.561 -7.185  1.0 98.54 ? 247 GLN A OE1 1 O43570 UNP 247 Q 
ATOM 1950 N N   . GLU A 1 248 ? -17.356 -11.756 -10.100 1.0 98.58 ? 248 GLU A N   1 O43570 UNP 248 E 
ATOM 1951 C CA  . GLU A 1 248 ? -17.115 -11.430 -11.506 1.0 98.58 ? 248 GLU A CA  1 O43570 UNP 248 E 
ATOM 1952 C C   . GLU A 1 248 ? -16.266 -10.163 -11.659 1.0 98.58 ? 248 GLU A C   1 O43570 UNP 248 E 
ATOM 1953 C CB  . GLU A 1 248 ? -18.449 -11.236 -12.249 1.0 98.58 ? 248 GLU A CB  1 O43570 UNP 248 E 
ATOM 1954 O O   . GLU A 1 248 ? -15.378 -10.118 -12.508 1.0 98.58 ? 248 GLU A O   1 O43570 UNP 248 E 
ATOM 1955 C CG  . GLU A 1 248 ? -19.337 -12.491 -12.325 1.0 98.58 ? 248 GLU A CG  1 O43570 UNP 248 E 
ATOM 1956 C CD  . GLU A 1 248 ? -20.036 -12.880 -11.010 1.0 98.58 ? 248 GLU A CD  1 O43570 UNP 248 E 
ATOM 1957 O OE1 . GLU A 1 248 ? -20.478 -14.045 -10.928 1.0 98.58 ? 248 GLU A OE1 1 O43570 UNP 248 E 
ATOM 1958 O OE2 . GLU A 1 248 ? -20.122 -12.030 -10.091 1.0 98.58 ? 248 GLU A OE2 1 O43570 UNP 248 E 
ATOM 1959 N N   . GLN A 1 249 ? -16.500 -9.150  -10.819 1.0 98.79 ? 249 GLN A N   1 O43570 UNP 249 Q 
ATOM 1960 C CA  . GLN A 1 249 ? -15.694 -7.927  -10.806 1.0 98.79 ? 249 GLN A CA  1 O43570 UNP 249 Q 
ATOM 1961 C C   . GLN A 1 249 ? -14.259 -8.188  -10.344 1.0 98.79 ? 249 GLN A C   1 O43570 UNP 249 Q 
ATOM 1962 C CB  . GLN A 1 249 ? -16.351 -6.871  -9.911  1.0 98.79 ? 249 GLN A CB  1 O43570 UNP 249 Q 
ATOM 1963 O O   . GLN A 1 249 ? -13.328 -7.669  -10.961 1.0 98.79 ? 249 GLN A O   1 O43570 UNP 249 Q 
ATOM 1964 C CG  . GLN A 1 249 ? -17.532 -6.194  -10.613 1.0 98.79 ? 249 GLN A CG  1 O43570 UNP 249 Q 
ATOM 1965 C CD  . GLN A 1 249 ? -18.209 -5.185  -9.700  1.0 98.79 ? 249 GLN A CD  1 O43570 UNP 249 Q 
ATOM 1966 N NE2 . GLN A 1 249 ? -18.337 -3.959  -10.153 1.0 98.79 ? 249 GLN A NE2 1 O43570 UNP 249 Q 
ATOM 1967 O OE1 . GLN A 1 249 ? -18.627 -5.501  -8.586  1.0 98.79 ? 249 GLN A OE1 1 O43570 UNP 249 Q 
ATOM 1968 N N   . LEU A 1 250 ? -14.067 -9.005  -9.302  1.0 98.78 ? 250 LEU A N   1 O43570 UNP 250 L 
ATOM 1969 C CA  . LEU A 1 250 ? -12.729 -9.391  -8.854  1.0 98.78 ? 250 LEU A CA  1 O43570 UNP 250 L 
ATOM 1970 C C   . LEU A 1 250 ? -11.992 -10.175 -9.946  1.0 98.78 ? 250 LEU A C   1 O43570 UNP 250 L 
ATOM 1971 C CB  . LEU A 1 250 ? -12.826 -10.190 -7.542  1.0 98.78 ? 250 LEU A CB  1 O43570 UNP 250 L 
ATOM 1972 O O   . LEU A 1 250 ? -10.875 -9.818  -10.306 1.0 98.78 ? 250 LEU A O   1 O43570 UNP 250 L 
ATOM 1973 C CG  . LEU A 1 250 ? -11.449 -10.615 -6.993  1.0 98.78 ? 250 LEU A CG  1 O43570 UNP 250 L 
ATOM 1974 C CD1 . LEU A 1 250 ? -10.562 -9.424  -6.619  1.0 98.78 ? 250 LEU A CD1 1 O43570 UNP 250 L 
ATOM 1975 C CD2 . LEU A 1 250 ? -11.649 -11.473 -5.749  1.0 98.78 ? 250 LEU A CD2 1 O43570 UNP 250 L 
ATOM 1976 N N   . LEU A 1 251 ? -12.647 -11.171 -10.547 1.0 98.69 ? 251 LEU A N   1 O43570 UNP 251 L 
ATOM 1977 C CA  . LEU A 1 251 ? -12.059 -11.961 -11.627 1.0 98.69 ? 251 LEU A CA  1 O43570 UNP 251 L 
ATOM 1978 C C   . LEU A 1 251 ? -11.701 -11.092 -12.843 1.0 98.69 ? 251 LEU A C   1 O43570 UNP 251 L 
ATOM 1979 C CB  . LEU A 1 251 ? -13.049 -13.076 -12.005 1.0 98.69 ? 251 LEU A CB  1 O43570 UNP 251 L 
ATOM 1980 O O   . LEU A 1 251 ? -10.657 -11.295 -13.465 1.0 98.69 ? 251 LEU A O   1 O43570 UNP 251 L 
ATOM 1981 C CG  . LEU A 1 251 ? -12.533 -14.024 -13.102 1.0 98.69 ? 251 LEU A CG  1 O43570 UNP 251 L 
ATOM 1982 C CD1 . LEU A 1 251 ? -11.295 -14.804 -12.658 1.0 98.69 ? 251 LEU A CD1 1 O43570 UNP 251 L 
ATOM 1983 C CD2 . LEU A 1 251 ? -13.628 -15.027 -13.468 1.0 98.69 ? 251 LEU A CD2 1 O43570 UNP 251 L 
ATOM 1984 N N   . ALA A 1 252 ? -12.541 -10.111 -13.186 1.0 98.55 ? 252 ALA A N   1 O43570 UNP 252 A 
ATOM 1985 C CA  . ALA A 1 252 ? -12.243 -9.157  -14.249 1.0 98.55 ? 252 ALA A CA  1 O43570 UNP 252 A 
ATOM 1986 C C   . ALA A 1 252 ? -10.996 -8.321  -13.922 1.0 98.55 ? 252 ALA A C   1 O43570 UNP 252 A 
ATOM 1987 C CB  . ALA A 1 252 ? -13.472 -8.274  -14.497 1.0 98.55 ? 252 ALA A CB  1 O43570 UNP 252 A 
ATOM 1988 O O   . ALA A 1 252 ? -10.129 -8.172  -14.784 1.0 98.55 ? 252 ALA A O   1 O43570 UNP 252 A 
ATOM 1989 N N   . LEU A 1 253 ? -10.863 -7.826  -12.687 1.0 98.70 ? 253 LEU A N   1 O43570 UNP 253 L 
ATOM 1990 C CA  . LEU A 1 253 ? -9.671  -7.101  -12.237 1.0 98.70 ? 253 LEU A CA  1 O43570 UNP 253 L 
ATOM 1991 C C   . LEU A 1 253 ? -8.406  -7.969  -12.338 1.0 98.70 ? 253 LEU A C   1 O43570 UNP 253 L 
ATOM 1992 C CB  . LEU A 1 253 ? -9.917  -6.588  -10.805 1.0 98.70 ? 253 LEU A CB  1 O43570 UNP 253 L 
ATOM 1993 O O   . LEU A 1 253 ? -7.393  -7.517  -12.869 1.0 98.70 ? 253 LEU A O   1 O43570 UNP 253 L 
ATOM 1994 C CG  . LEU A 1 253 ? -8.746  -5.794  -10.199 1.0 98.70 ? 253 LEU A CG  1 O43570 UNP 253 L 
ATOM 1995 C CD1 . LEU A 1 253 ? -8.444  -4.521  -10.997 1.0 98.70 ? 253 LEU A CD1 1 O43570 UNP 253 L 
ATOM 1996 C CD2 . LEU A 1 253 ? -9.089  -5.392  -8.763  1.0 98.70 ? 253 LEU A CD2 1 O43570 UNP 253 L 
ATOM 1997 N N   . GLU A 1 254 ? -8.491  -9.227  -11.907 1.0 98.65 ? 254 GLU A N   1 O43570 UNP 254 E 
ATOM 1998 C CA  . GLU A 1 254 ? -7.369  -10.171 -11.862 1.0 98.65 ? 254 GLU A CA  1 O43570 UNP 254 E 
ATOM 1999 C C   . GLU A 1 254 ? -6.920  -10.691 -13.238 1.0 98.65 ? 254 GLU A C   1 O43570 UNP 254 E 
ATOM 2000 C CB  . GLU A 1 254 ? -7.762  -11.355 -10.968 1.0 98.65 ? 254 GLU A CB  1 O43570 UNP 254 E 
ATOM 2001 O O   . GLU A 1 254 ? -5.806  -11.192 -13.362 1.0 98.65 ? 254 GLU A O   1 O43570 UNP 254 E 
ATOM 2002 C CG  . GLU A 1 254 ? -7.864  -10.978 -9.482  1.0 98.65 ? 254 GLU A CG  1 O43570 UNP 254 E 
ATOM 2003 C CD  . GLU A 1 254 ? -8.396  -12.125 -8.612  1.0 98.65 ? 254 GLU A CD  1 O43570 UNP 254 E 
ATOM 2004 O OE1 . GLU A 1 254 ? -8.107  -12.084 -7.396  1.0 98.65 ? 254 GLU A OE1 1 O43570 UNP 254 E 
ATOM 2005 O OE2 . GLU A 1 254 ? -9.057  -13.041 -9.157  1.0 98.65 ? 254 GLU A OE2 1 O43570 UNP 254 E 
ATOM 2006 N N   . THR A 1 255 ? -7.756  -10.588 -14.279 1.0 98.51 ? 255 THR A N   1 O43570 UNP 255 T 
ATOM 2007 C CA  . THR A 1 255 ? -7.487  -11.209 -15.596 1.0 98.51 ? 255 THR A CA  1 O43570 UNP 255 T 
ATOM 2008 C C   . THR A 1 255 ? -7.485  -10.233 -16.775 1.0 98.51 ? 255 THR A C   1 O43570 UNP 255 T 
ATOM 2009 C CB  . THR A 1 255 ? -8.474  -12.349 -15.883 1.0 98.51 ? 255 THR A CB  1 O43570 UNP 255 T 
ATOM 2010 O O   . THR A 1 255 ? -7.053  -10.584 -17.877 1.0 98.51 ? 255 THR A O   1 O43570 UNP 255 T 
ATOM 2011 C CG2 . THR A 1 255 ? -8.425  -13.463 -14.838 1.0 98.51 ? 255 THR A CG2 1 O43570 UNP 255 T 
ATOM 2012 O OG1 . THR A 1 255 ? -9.795  -11.862 -15.941 1.0 98.51 ? 255 THR A OG1 1 O43570 UNP 255 T 
ATOM 2013 N N   . ALA A 1 256 ? -7.951  -8.992  -16.599 1.0 98.51 ? 256 ALA A N   1 O43570 UNP 256 A 
ATOM 2014 C CA  . ALA A 1 256 ? -8.102  -8.065  -17.721 1.0 98.51 ? 256 ALA A CA  1 O43570 UNP 256 A 
ATOM 2015 C C   . ALA A 1 256 ? -6.778  -7.485  -18.246 1.0 98.51 ? 256 ALA A C   1 O43570 UNP 256 A 
ATOM 2016 C CB  . ALA A 1 256 ? -9.071  -6.943  -17.333 1.0 98.51 ? 256 ALA A CB  1 O43570 UNP 256 A 
ATOM 2017 O O   . ALA A 1 256 ? -6.734  -7.086  -19.418 1.0 98.51 ? 256 ALA A O   1 O43570 UNP 256 A 
ATOM 2018 N N   . LEU A 1 257 ? -5.733  -7.425  -17.413 1.0 98.73 ? 257 LEU A N   1 O43570 UNP 257 L 
ATOM 2019 C CA  . LEU A 1 257 ? -4.568  -6.553  -17.593 1.0 98.73 ? 257 LEU A CA  1 O43570 UNP 257 L 
ATOM 2020 C C   . LEU A 1 257 ? -3.243  -7.322  -17.743 1.0 98.73 ? 257 LEU A C   1 O43570 UNP 257 L 
ATOM 2021 C CB  . LEU A 1 257 ? -4.488  -5.587  -16.396 1.0 98.73 ? 257 LEU A CB  1 O43570 UNP 257 L 
ATOM 2022 O O   . LEU A 1 257 ? -3.026  -8.366  -17.137 1.0 98.73 ? 257 LEU A O   1 O43570 UNP 257 L 
ATOM 2023 C CG  . LEU A 1 257 ? -5.722  -4.703  -16.142 1.0 98.73 ? 257 LEU A CG  1 O43570 UNP 257 L 
ATOM 2024 C CD1 . LEU A 1 257 ? -5.481  -3.899  -14.869 1.0 98.73 ? 257 LEU A CD1 1 O43570 UNP 257 L 
ATOM 2025 C CD2 . LEU A 1 257 ? -6.000  -3.734  -17.290 1.0 98.73 ? 257 LEU A CD2 1 O43570 UNP 257 L 
ATOM 2026 N N   . TYR A 1 258 ? -2.315  -6.743  -18.503 1.0 98.50 ? 258 TYR A N   1 O43570 UNP 258 Y 
ATOM 2027 C CA  . TYR A 1 258 ? -0.948  -7.214  -18.718 1.0 98.50 ? 258 TYR A CA  1 O43570 UNP 258 Y 
ATOM 2028 C C   . TYR A 1 258 ? 0.062   -6.129  -18.319 1.0 98.50 ? 258 TYR A C   1 O43570 UNP 258 Y 
ATOM 2029 C CB  . TYR A 1 258 ? -0.753  -7.629  -20.188 1.0 98.50 ? 258 TYR A CB  1 O43570 UNP 258 Y 
ATOM 2030 O O   . TYR A 1 258 ? -0.108  -4.949  -18.633 1.0 98.50 ? 258 TYR A O   1 O43570 UNP 258 Y 
ATOM 2031 C CG  . TYR A 1 258 ? -1.439  -8.926  -20.579 1.0 98.50 ? 258 TYR A CG  1 O43570 UNP 258 Y 
ATOM 2032 C CD1 . TYR A 1 258 ? -0.713  -10.132 -20.606 1.0 98.50 ? 258 TYR A CD1 1 O43570 UNP 258 Y 
ATOM 2033 C CD2 . TYR A 1 258 ? -2.812  -8.934  -20.887 1.0 98.50 ? 258 TYR A CD2 1 O43570 UNP 258 Y 
ATOM 2034 C CE1 . TYR A 1 258 ? -1.361  -11.351 -20.887 1.0 98.50 ? 258 TYR A CE1 1 O43570 UNP 258 Y 
ATOM 2035 C CE2 . TYR A 1 258 ? -3.458  -10.145 -21.202 1.0 98.50 ? 258 TYR A CE2 1 O43570 UNP 258 Y 
ATOM 2036 O OH  . TYR A 1 258 ? -3.392  -12.523 -21.431 1.0 98.50 ? 258 TYR A OH  1 O43570 UNP 258 Y 
ATOM 2037 C CZ  . TYR A 1 258 ? -2.740  -11.358 -21.182 1.0 98.50 ? 258 TYR A CZ  1 O43570 UNP 258 Y 
ATOM 2038 N N   . CYS A 1 259 ? 1.171   -6.538  -17.696 1.0 97.49 ? 259 CYS A N   1 O43570 UNP 259 C 
ATOM 2039 C CA  . CYS A 1 259 ? 2.310   -5.676  -17.337 1.0 97.49 ? 259 CYS A CA  1 O43570 UNP 259 C 
ATOM 2040 C C   . CYS A 1 259 ? 3.186   -5.280  -18.540 1.0 97.49 ? 259 CYS A C   1 O43570 UNP 259 C 
ATOM 2041 C CB  . CYS A 1 259 ? 3.187   -6.423  -16.323 1.0 97.49 ? 259 CYS A CB  1 O43570 UNP 259 C 
ATOM 2042 O O   . CYS A 1 259 ? 4.155   -4.532  -18.405 1.0 97.49 ? 259 CYS A O   1 O43570 UNP 259 C 
ATOM 2043 S SG  . CYS A 1 259 ? 2.285   -6.679  -14.780 1.0 97.49 ? 259 CYS A SG  1 O43570 UNP 259 C 
ATOM 2044 N N   . THR A 1 260 ? 2.900   -5.848  -19.708 1.0 97.18 ? 260 THR A N   1 O43570 UNP 260 T 
ATOM 2045 C CA  . THR A 1 260 ? 3.726   -5.809  -20.923 1.0 97.18 ? 260 THR A CA  1 O43570 UNP 260 T 
ATOM 2046 C C   . THR A 1 260 ? 3.043   -4.980  -22.002 1.0 97.18 ? 260 THR A C   1 O43570 UNP 260 T 
ATOM 2047 C CB  . THR A 1 260 ? 4.038   -7.233  -21.418 1.0 97.18 ? 260 THR A CB  1 O43570 UNP 260 T 
ATOM 2048 O O   . THR A 1 260 ? 1.830   -4.763  -21.945 1.0 97.18 ? 260 THR A O   1 O43570 UNP 260 T 
ATOM 2049 C CG2 . THR A 1 260 ? 5.120   -7.884  -20.558 1.0 97.18 ? 260 THR A CG2 1 O43570 UNP 260 T 
ATOM 2050 O OG1 . THR A 1 260 ? 2.901   -8.061  -21.308 1.0 97.18 ? 260 THR A OG1 1 O43570 UNP 260 T 
ATOM 2051 N N   . HIS A 1 261 ? 3.823   -4.461  -22.951 1.0 97.39 ? 261 HIS A N   1 O43570 UNP 261 H 
ATOM 2052 C CA  . HIS A 1 261 ? 3.265   -3.781  -24.121 1.0 97.39 ? 261 HIS A CA  1 O43570 UNP 261 H 
ATOM 2053 C C   . HIS A 1 261 ? 2.556   -4.795  -25.034 1.0 97.39 ? 261 HIS A C   1 O43570 UNP 261 H 
ATOM 2054 C CB  . HIS A 1 261 ? 4.368   -2.998  -24.848 1.0 97.39 ? 261 HIS A CB  1 O43570 UNP 261 H 
ATOM 2055 O O   . HIS A 1 261 ? 2.799   -5.996  -24.947 1.0 97.39 ? 261 HIS A O   1 O43570 UNP 261 H 
ATOM 2056 C CG  . HIS A 1 261 ? 4.872   -1.814  -24.056 1.0 97.39 ? 261 HIS A CG  1 O43570 UNP 261 H 
ATOM 2057 C CD2 . HIS A 1 261 ? 6.070   -1.700  -23.405 1.0 97.39 ? 261 HIS A CD2 1 O43570 UNP 261 H 
ATOM 2058 N ND1 . HIS A 1 261 ? 4.187   -0.642  -23.838 1.0 97.39 ? 261 HIS A ND1 1 O43570 UNP 261 H 
ATOM 2059 C CE1 . HIS A 1 261 ? 4.955   0.161   -23.089 1.0 97.39 ? 261 HIS A CE1 1 O43570 UNP 261 H 
ATOM 2060 N NE2 . HIS A 1 261 ? 6.106   -0.452  -22.758 1.0 97.39 ? 261 HIS A NE2 1 O43570 UNP 261 H 
ATOM 2061 N N   . MET A 1 262 ? 1.653   -4.317  -25.893 1.0 97.14 ? 262 MET A N   1 O43570 UNP 262 M 
ATOM 2062 C CA  . MET A 1 262 ? 0.815   -5.176  -26.745 1.0 97.14 ? 262 MET A CA  1 O43570 UNP 262 M 
ATOM 2063 C C   . MET A 1 262 ? 1.623   -6.017  -27.747 1.0 97.14 ? 262 MET A C   1 O43570 UNP 262 M 
ATOM 2064 C CB  . MET A 1 262 ? -0.184  -4.271  -27.479 1.0 97.14 ? 262 MET A CB  1 O43570 UNP 262 M 
ATOM 2065 O O   . MET A 1 262 ? 1.184   -7.089  -28.147 1.0 97.14 ? 262 MET A O   1 O43570 UNP 262 M 
ATOM 2066 C CG  . MET A 1 262 ? -1.204  -5.046  -28.320 1.0 97.14 ? 262 MET A CG  1 O43570 UNP 262 M 
ATOM 2067 S SD  . MET A 1 262 ? -2.488  -4.001  -29.064 1.0 97.14 ? 262 MET A SD  1 O43570 UNP 262 M 
ATOM 2068 C CE  . MET A 1 262 ? -1.502  -3.152  -30.329 1.0 97.14 ? 262 MET A CE  1 O43570 UNP 262 M 
ATOM 2069 N N   . ASP A 1 263 ? 2.787   -5.521  -28.155 1.0 96.65 ? 263 ASP A N   1 O43570 UNP 263 D 
ATOM 2070 C CA  . ASP A 1 263 ? 3.718   -6.143  -29.094 1.0 96.65 ? 263 ASP A CA  1 O43570 UNP 263 D 
ATOM 2071 C C   . ASP A 1 263 ? 4.821   -6.967  -28.406 1.0 96.65 ? 263 ASP A C   1 O43570 UNP 263 D 
ATOM 2072 C CB  . ASP A 1 263 ? 4.295   -5.045  -30.007 1.0 96.65 ? 263 ASP A CB  1 O43570 UNP 263 D 
ATOM 2073 O O   . ASP A 1 263 ? 5.727   -7.463  -29.078 1.0 96.65 ? 263 ASP A O   1 O43570 UNP 263 D 
ATOM 2074 C CG  . ASP A 1 263 ? 5.082   -3.941  -29.277 1.0 96.65 ? 263 ASP A CG  1 O43570 UNP 263 D 
ATOM 2075 O OD1 . ASP A 1 263 ? 4.886   -3.759  -28.049 1.0 96.65 ? 263 ASP A OD1 1 O43570 UNP 263 D 
ATOM 2076 O OD2 . ASP A 1 263 ? 5.817   -3.213  -29.981 1.0 96.65 ? 263 ASP A OD2 1 O43570 UNP 263 D 
ATOM 2077 N N   . ASP A 1 264 ? 4.755   -7.140  -27.081 1.0 96.25 ? 264 ASP A N   1 O43570 UNP 264 D 
ATOM 2078 C CA  . ASP A 1 264 ? 5.722   -7.946  -26.340 1.0 96.25 ? 264 ASP A CA  1 O43570 UNP 264 D 
ATOM 2079 C C   . ASP A 1 264 ? 5.536   -9.440  -26.679 1.0 96.25 ? 264 ASP A C   1 O43570 UNP 264 D 
ATOM 2080 C CB  . ASP A 1 264 ? 5.592   -7.677  -24.833 1.0 96.25 ? 264 ASP A CB  1 O43570 UNP 264 D 
ATOM 2081 O O   . ASP A 1 264 ? 4.460   -9.999  -26.436 1.0 96.25 ? 264 ASP A O   1 O43570 UNP 264 D 
ATOM 2082 C CG  . ASP A 1 264 ? 6.795   -8.170  -24.019 1.0 96.25 ? 264 ASP A CG  1 O43570 UNP 264 D 
ATOM 2083 O OD1 . ASP A 1 264 ? 7.307   -9.278  -24.311 1.0 96.25 ? 264 ASP A OD1 1 O43570 UNP 264 D 
ATOM 2084 O OD2 . ASP A 1 264 ? 7.197   -7.426  -23.090 1.0 96.25 ? 264 ASP A OD2 1 O43570 UNP 264 D 
ATOM 2085 N N   . PRO A 1 265 ? 6.561   -10.128 -27.220 1.0 96.62 ? 265 PRO A N   1 O43570 UNP 265 P 
ATOM 2086 C CA  . PRO A 1 265 ? 6.455   -11.542 -27.572 1.0 96.62 ? 265 PRO A CA  1 O43570 UNP 265 P 
ATOM 2087 C C   . PRO A 1 265 ? 6.317   -12.461 -26.349 1.0 96.62 ? 265 PRO A C   1 O43570 UNP 265 P 
ATOM 2088 C CB  . PRO A 1 265 ? 7.730   -11.843 -28.366 1.0 96.62 ? 265 PRO A CB  1 O43570 UNP 265 P 
ATOM 2089 O O   . PRO A 1 265 ? 6.068   -13.654 -26.509 1.0 96.62 ? 265 PRO A O   1 O43570 UNP 265 P 
ATOM 2090 C CG  . PRO A 1 265 ? 8.746   -10.858 -27.789 1.0 96.62 ? 265 PRO A CG  1 O43570 UNP 265 P 
ATOM 2091 C CD  . PRO A 1 265 ? 7.893   -9.622  -27.521 1.0 96.62 ? 265 PRO A CD  1 O43570 UNP 265 P 
ATOM 2092 N N   . SER A 1 266 ? 6.528   -11.950 -25.132 1.0 96.44 ? 266 SER A N   1 O43570 UNP 266 S 
ATOM 2093 C CA  . SER A 1 266 ? 6.421   -12.690 -23.870 1.0 96.44 ? 266 SER A CA  1 O43570 UNP 266 S 
ATOM 2094 C C   . SER A 1 266 ? 5.456   -11.972 -22.917 1.0 96.44 ? 266 SER A C   1 O43570 UNP 266 S 
ATOM 2095 C CB  . SER A 1 266 ? 7.811   -12.864 -23.259 1.0 96.44 ? 266 SER A CB  1 O43570 UNP 266 S 
ATOM 2096 O O   . SER A 1 266 ? 5.895   -11.394 -21.916 1.0 96.44 ? 266 SER A O   1 O43570 UNP 266 S 
ATOM 2097 O OG  . SER A 1 266 ? 8.630   -13.537 -24.192 1.0 96.44 ? 266 SER A OG  1 O43570 UNP 266 S 
ATOM 2098 N N   . PRO A 1 267 ? 4.140   -11.986 -23.209 1.0 95.70 ? 267 PRO A N   1 O43570 UNP 267 P 
ATOM 2099 C CA  . PRO A 1 267 ? 3.158   -11.256 -22.425 1.0 95.70 ? 267 PRO A CA  1 O43570 UNP 267 P 
ATOM 2100 C C   . PRO A 1 267 ? 3.122   -11.773 -20.986 1.0 95.70 ? 267 PRO A C   1 O43570 UNP 267 P 
ATOM 2101 C CB  . PRO A 1 267 ? 1.822   -11.439 -23.150 1.0 95.70 ? 267 PRO A CB  1 O43570 UNP 267 P 
ATOM 2102 O O   . PRO A 1 267 ? 3.134   -12.976 -20.729 1.0 95.70 ? 267 PRO A O   1 O43570 UNP 267 P 
ATOM 2103 C CG  . PRO A 1 267 ? 1.996   -12.778 -23.863 1.0 95.70 ? 267 PRO A CG  1 O43570 UNP 267 P 
ATOM 2104 C CD  . PRO A 1 267 ? 3.474   -12.759 -24.250 1.0 95.70 ? 267 PRO A CD  1 O43570 UNP 267 P 
ATOM 2105 N N   . ARG A 1 268 ? 3.066   -10.843 -20.033 1.0 97.33 ? 268 ARG A N   1 O43570 UNP 268 R 
ATOM 2106 C CA  . ARG A 1 268 ? 2.949   -11.146 -18.600 1.0 97.33 ? 268 ARG A CA  1 O43570 UNP 268 R 
ATOM 2107 C C   . ARG A 1 268 ? 1.681   -10.520 -18.054 1.0 97.33 ? 268 ARG A C   1 O43570 UNP 268 R 
ATOM 2108 C CB  . ARG A 1 268 ? 4.194   -10.679 -17.829 1.0 97.33 ? 268 ARG A CB  1 O43570 UNP 268 R 
ATOM 2109 O O   . ARG A 1 268 ? 1.527   -9.300  -18.151 1.0 97.33 ? 268 ARG A O   1 O43570 UNP 268 R 
ATOM 2110 C CG  . ARG A 1 268 ? 5.467   -11.392 -18.319 1.0 97.33 ? 268 ARG A CG  1 O43570 UNP 268 R 
ATOM 2111 C CD  . ARG A 1 268 ? 6.746   -10.976 -17.582 1.0 97.33 ? 268 ARG A CD  1 O43570 UNP 268 R 
ATOM 2112 N NE  . ARG A 1 268 ? 7.022   -9.532  -17.720 1.0 97.33 ? 268 ARG A NE  1 O43570 UNP 268 R 
ATOM 2113 N NH1 . ARG A 1 268 ? 7.609   -8.978  -15.546 1.0 97.33 ? 268 ARG A NH1 1 O43570 UNP 268 R 
ATOM 2114 N NH2 . ARG A 1 268 ? 7.655   -7.433  -17.138 1.0 97.33 ? 268 ARG A NH2 1 O43570 UNP 268 R 
ATOM 2115 C CZ  . ARG A 1 268 ? 7.422   -8.668  -16.799 1.0 97.33 ? 268 ARG A CZ  1 O43570 UNP 268 R 
ATOM 2116 N N   . GLU A 1 269 ? 0.801   -11.350 -17.511 1.0 98.16 ? 269 GLU A N   1 O43570 UNP 269 E 
ATOM 2117 C CA  . GLU A 1 269 ? -0.415  -10.915 -16.824 1.0 98.16 ? 269 GLU A CA  1 O43570 UNP 269 E 
ATOM 2118 C C   . GLU A 1 269 ? -0.061  -10.016 -15.633 1.0 98.16 ? 269 GLU A C   1 O43570 UNP 269 E 
ATOM 2119 C CB  . GLU A 1 269 ? -1.231  -12.135 -16.372 1.0 98.16 ? 269 GLU A CB  1 O43570 UNP 269 E 
ATOM 2120 O O   . GLU A 1 269 ? 0.992   -10.166 -15.003 1.0 98.16 ? 269 GLU A O   1 O43570 UNP 269 E 
ATOM 2121 C CG  . GLU A 1 269 ? -1.801  -12.893 -17.583 1.0 98.16 ? 269 GLU A CG  1 O43570 UNP 269 E 
ATOM 2122 C CD  . GLU A 1 269 ? -2.533  -14.194 -17.223 1.0 98.16 ? 269 GLU A CD  1 O43570 UNP 269 E 
ATOM 2123 O OE1 . GLU A 1 269 ? -3.029  -14.824 -18.186 1.0 98.16 ? 269 GLU A OE1 1 O43570 UNP 269 E 
ATOM 2124 O OE2 . GLU A 1 269 ? -2.524  -14.582 -16.035 1.0 98.16 ? 269 GLU A OE2 1 O43570 UNP 269 E 
ATOM 2125 N N   . MET A 1 270 ? -0.923  -9.041  -15.356 1.0 98.57 ? 270 MET A N   1 O43570 UNP 270 M 
ATOM 2126 C CA  . MET A 1 270 ? -0.798  -8.162  -14.201 1.0 98.57 ? 270 MET A CA  1 O43570 UNP 270 M 
ATOM 2127 C C   . MET A 1 270 ? -1.542  -8.786  -13.030 1.0 98.57 ? 270 MET A C   1 O43570 UNP 270 M 
ATOM 2128 C CB  . MET A 1 270 ? -1.283  -6.755  -14.558 1.0 98.57 ? 270 MET A CB  1 O43570 UNP 270 M 
ATOM 2129 O O   . MET A 1 270 ? -2.723  -8.535  -12.827 1.0 98.57 ? 270 MET A O   1 O43570 UNP 270 M 
ATOM 2130 C CG  . MET A 1 270 ? -1.004  -5.753  -13.432 1.0 98.57 ? 270 MET A CG  1 O43570 UNP 270 M 
ATOM 2131 S SD  . MET A 1 270 ? -1.522  -4.057  -13.805 1.0 98.57 ? 270 MET A SD  1 O43570 UNP 270 M 
ATOM 2132 C CE  . MET A 1 270 ? -0.385  -3.659  -15.146 1.0 98.57 ? 270 MET A CE  1 O43570 UNP 270 M 
ATOM 2133 N N   . ILE A 1 271 ? -0.825  -9.619  -12.287 1.0 98.59 ? 271 ILE A N   1 O43570 UNP 271 I 
ATOM 2134 C CA  . ILE A 1 271 ? -1.306  -10.317 -11.095 1.0 98.59 ? 271 ILE A CA  1 O43570 UNP 271 I 
ATOM 2135 C C   . ILE A 1 271 ? -0.293  -10.177 -9.963  1.0 98.59 ? 271 ILE A C   1 O43570 UNP 271 I 
ATOM 2136 C CB  . ILE A 1 271 ? -1.586  -11.803 -11.400 1.0 98.59 ? 271 ILE A CB  1 O43570 UNP 271 I 
ATOM 2137 O O   . ILE A 1 271 ? 0.893   -9.940  -10.221 1.0 98.59 ? 271 ILE A O   1 O43570 UNP 271 I 
ATOM 2138 C CG1 . ILE A 1 271 ? -0.352  -12.545 -11.966 1.0 98.59 ? 271 ILE A CG1 1 O43570 UNP 271 I 
ATOM 2139 C CG2 . ILE A 1 271 ? -2.810  -11.934 -12.317 1.0 98.59 ? 271 ILE A CG2 1 O43570 UNP 271 I 
ATOM 2140 C CD1 . ILE A 1 271 ? -0.532  -14.066 -12.046 1.0 98.59 ? 271 ILE A CD1 1 O43570 UNP 271 I 
ATOM 2141 N N   . ASN A 1 272 ? -0.752  -10.366 -8.724  1.0 98.55 ? 272 ASN A N   1 O43570 UNP 272 N 
ATOM 2142 C CA  . ASN A 1 272 ? 0.069   -10.283 -7.513  1.0 98.55 ? 272 ASN A CA  1 O43570 UNP 272 N 
ATOM 2143 C C   . ASN A 1 272 ? 0.878   -8.980  -7.457  1.0 98.55 ? 272 ASN A C   1 O43570 UNP 272 N 
ATOM 2144 C CB  . ASN A 1 272 ? 0.933   -11.549 -7.370  1.0 98.55 ? 272 ASN A CB  1 O43570 UNP 272 N 
ATOM 2145 O O   . ASN A 1 272 ? 2.085   -8.980  -7.205  1.0 98.55 ? 272 ASN A O   1 O43570 UNP 272 N 
ATOM 2146 C CG  . ASN A 1 272 ? 0.109   -12.817 -7.375  1.0 98.55 ? 272 ASN A CG  1 O43570 UNP 272 N 
ATOM 2147 N ND2 . ASN A 1 272 ? 0.596   -13.878 -7.976  1.0 98.55 ? 272 ASN A ND2 1 O43570 UNP 272 N 
ATOM 2148 O OD1 . ASN A 1 272 ? -0.990  -12.886 -6.855  1.0 98.55 ? 272 ASN A OD1 1 O43570 UNP 272 N 
ATOM 2149 N N   . ASN A 1 273 ? 0.219   -7.864  -7.766  1.0 98.64 ? 273 ASN A N   1 O43570 UNP 273 N 
ATOM 2150 C CA  . ASN A 1 273 ? 0.841   -6.548  -7.813  1.0 98.64 ? 273 ASN A CA  1 O43570 UNP 273 N 
ATOM 2151 C C   . ASN A 1 273 ? 0.784   -5.838  -6.455  1.0 98.64 ? 273 ASN A C   1 O43570 UNP 273 N 
ATOM 2152 C CB  . ASN A 1 273 ? 0.285   -5.725  -8.989  1.0 98.64 ? 273 ASN A CB  1 O43570 UNP 273 N 
ATOM 2153 O O   . ASN A 1 273 ? 0.588   -4.630  -6.405  1.0 98.64 ? 273 ASN A O   1 O43570 UNP 273 N 
ATOM 2154 C CG  . ASN A 1 273 ? -1.167  -5.319  -8.816  1.0 98.64 ? 273 ASN A CG  1 O43570 UNP 273 N 
ATOM 2155 N ND2 . ASN A 1 273 ? -1.569  -4.226  -9.413  1.0 98.64 ? 273 ASN A ND2 1 O43570 UNP 273 N 
ATOM 2156 O OD1 . ASN A 1 273 ? -1.952  -5.984  -8.171  1.0 98.64 ? 273 ASN A OD1 1 O43570 UNP 273 N 
ATOM 2157 N N   . PHE A 1 274 ? 0.971   -6.574  -5.363  1.0 98.75 ? 274 PHE A N   1 O43570 UNP 274 F 
ATOM 2158 C CA  . PHE A 1 274 ? 1.024   -6.068  -3.993  1.0 98.75 ? 274 PHE A CA  1 O43570 UNP 274 F 
ATOM 2159 C C   . PHE A 1 274 ? 2.385   -6.384  -3.371  1.0 98.75 ? 274 PHE A C   1 O43570 UNP 274 F 
ATOM 2160 C CB  . PHE A 1 274 ? -0.126  -6.665  -3.174  1.0 98.75 ? 274 PHE A CB  1 O43570 UNP 274 F 
ATOM 2161 O O   . PHE A 1 274 ? 3.013   -7.395  -3.694  1.0 98.75 ? 274 PHE A O   1 O43570 UNP 274 F 
ATOM 2162 C CG  . PHE A 1 274 ? -0.093  -8.169  -3.025  1.0 98.75 ? 274 PHE A CG  1 O43570 UNP 274 F 
ATOM 2163 C CD1 . PHE A 1 274 ? -0.665  -8.992  -4.011  1.0 98.75 ? 274 PHE A CD1 1 O43570 UNP 274 F 
ATOM 2164 C CD2 . PHE A 1 274 ? 0.481   -8.742  -1.876  1.0 98.75 ? 274 PHE A CD2 1 O43570 UNP 274 F 
ATOM 2165 C CE1 . PHE A 1 274 ? -0.660  -10.389 -3.848  1.0 98.75 ? 274 PHE A CE1 1 O43570 UNP 274 F 
ATOM 2166 C CE2 . PHE A 1 274 ? 0.474   -10.136 -1.708  1.0 98.75 ? 274 PHE A CE2 1 O43570 UNP 274 F 
ATOM 2167 C CZ  . PHE A 1 274 ? -0.099  -10.959 -2.693  1.0 98.75 ? 274 PHE A CZ  1 O43570 UNP 274 F 
ATOM 2168 N N   . ARG A 1 275 ? 2.872   -5.500  -2.501  1.0 98.73 ? 275 ARG A N   1 O43570 UNP 275 R 
ATOM 2169 C CA  . ARG A 1 275 ? 4.117   -5.694  -1.751  1.0 98.73 ? 275 ARG A CA  1 O43570 UNP 275 R 
ATOM 2170 C C   . ARG A 1 275 ? 3.843   -6.492  -0.476  1.0 98.73 ? 275 ARG A C   1 O43570 UNP 275 R 
ATOM 2171 C CB  . ARG A 1 275 ? 4.713   -4.316  -1.443  1.0 98.73 ? 275 ARG A CB  1 O43570 UNP 275 R 
ATOM 2172 O O   . ARG A 1 275 ? 2.825   -6.275  0.176   1.0 98.73 ? 275 ARG A O   1 O43570 UNP 275 R 
ATOM 2173 C CG  . ARG A 1 275 ? 6.161   -4.412  -0.953  1.0 98.73 ? 275 ARG A CG  1 O43570 UNP 275 R 
ATOM 2174 C CD  . ARG A 1 275 ? 6.622   -3.060  -0.412  1.0 98.73 ? 275 ARG A CD  1 O43570 UNP 275 R 
ATOM 2175 N NE  . ARG A 1 275 ? 8.082   -3.030  -0.242  1.0 98.73 ? 275 ARG A NE  1 O43570 UNP 275 R 
ATOM 2176 N NH1 . ARG A 1 275 ? 8.219   -0.887  0.571   1.0 98.73 ? 275 ARG A NH1 1 O43570 UNP 275 R 
ATOM 2177 N NH2 . ARG A 1 275 ? 10.067  -2.102  0.367   1.0 98.73 ? 275 ARG A NH2 1 O43570 UNP 275 R 
ATOM 2178 C CZ  . ARG A 1 275 ? 8.778   -2.009  0.216   1.0 98.73 ? 275 ARG A CZ  1 O43570 UNP 275 R 
ATOM 2179 N N   . GLN A 1 276 ? 4.778   -7.349  -0.067  1.0 98.59 ? 276 GLN A N   1 O43570 UNP 276 Q 
ATOM 2180 C CA  . GLN A 1 276 ? 4.688   -8.017  1.233   1.0 98.59 ? 276 GLN A CA  1 O43570 UNP 276 Q 
ATOM 2181 C C   . GLN A 1 276 ? 4.683   -7.016  2.397   1.0 98.59 ? 276 GLN A C   1 O43570 UNP 276 Q 
ATOM 2182 C CB  . GLN A 1 276 ? 5.830   -9.032  1.409   1.0 98.59 ? 276 GLN A CB  1 O43570 UNP 276 Q 
ATOM 2183 O O   . GLN A 1 276 ? 5.278   -5.934  2.321   1.0 98.59 ? 276 GLN A O   1 O43570 UNP 276 Q 
ATOM 2184 C CG  . GLN A 1 276 ? 5.796   -10.166 0.373   1.0 98.59 ? 276 GLN A CG  1 O43570 UNP 276 Q 
ATOM 2185 C CD  . GLN A 1 276 ? 4.489   -10.945 0.377   1.0 98.59 ? 276 GLN A CD  1 O43570 UNP 276 Q 
ATOM 2186 N NE2 . GLN A 1 276 ? 4.071   -11.482 -0.746  1.0 98.59 ? 276 GLN A NE2 1 O43570 UNP 276 Q 
ATOM 2187 O OE1 . GLN A 1 276 ? 3.833   -11.096 1.391   1.0 98.59 ? 276 GLN A OE1 1 O43570 UNP 276 Q 
ATOM 2188 N N   . VAL A 1 277 ? 4.052   -7.396  3.511   1.0 98.71 ? 277 VAL A N   1 O43570 UNP 277 V 
ATOM 2189 C CA  . VAL A 1 277 ? 4.055   -6.586  4.736   1.0 98.71 ? 277 VAL A CA  1 O43570 UNP 277 V 
ATOM 2190 C C   . VAL A 1 277 ? 5.476   -6.354  5.250   1.0 98.71 ? 277 VAL A C   1 O43570 UNP 277 V 
ATOM 2191 C CB  . VAL A 1 277 ? 3.154   -7.158  5.844   1.0 98.71 ? 277 VAL A CB  1 O43570 UNP 277 V 
ATOM 2192 O O   . VAL A 1 277 ? 6.337   -7.235  5.247   1.0 98.71 ? 277 VAL A O   1 O43570 UNP 277 V 
ATOM 2193 C CG1 . VAL A 1 277 ? 1.684   -7.123  5.419   1.0 98.71 ? 277 VAL A CG1 1 O43570 UNP 277 V 
ATOM 2194 C CG2 . VAL A 1 277 ? 3.524   -8.587  6.257   1.0 98.71 ? 277 VAL A CG2 1 O43570 UNP 277 V 
ATOM 2195 N N   . GLN A 1 278 ? 5.729   -5.129  5.689   1.0 98.58 ? 278 GLN A N   1 O43570 UNP 278 Q 
ATOM 2196 C CA  . GLN A 1 278 ? 7.021   -4.670  6.172   1.0 98.58 ? 278 GLN A CA  1 O43570 UNP 278 Q 
ATOM 2197 C C   . GLN A 1 278 ? 7.055   -4.740  7.699   1.0 98.58 ? 278 GLN A C   1 O43570 UNP 278 Q 
ATOM 2198 C CB  . GLN A 1 278 ? 7.296   -3.253  5.641   1.0 98.58 ? 278 GLN A CB  1 O43570 UNP 278 Q 
ATOM 2199 O O   . GLN A 1 278 ? 6.034   -4.590  8.372   1.0 98.58 ? 278 GLN A O   1 O43570 UNP 278 Q 
ATOM 2200 C CG  . GLN A 1 278 ? 7.171   -3.155  4.107   1.0 98.58 ? 278 GLN A CG  1 O43570 UNP 278 Q 
ATOM 2201 C CD  . GLN A 1 278 ? 8.228   -3.961  3.361   1.0 98.58 ? 278 GLN A CD  1 O43570 UNP 278 Q 
ATOM 2202 N NE2 . GLN A 1 278 ? 7.843   -4.925  2.559   1.0 98.58 ? 278 GLN A NE2 1 O43570 UNP 278 Q 
ATOM 2203 O OE1 . GLN A 1 278 ? 9.423   -3.723  3.475   1.0 98.58 ? 278 GLN A OE1 1 O43570 UNP 278 Q 
ATOM 2204 N N   . LYS A 1 279 ? 8.247   -4.949  8.265   1.0 97.75 ? 279 LYS A N   1 O43570 UNP 279 K 
ATOM 2205 C CA  . LYS A 1 279 ? 8.425   -4.966  9.722   1.0 97.75 ? 279 LYS A CA  1 O43570 UNP 279 K 
ATOM 2206 C C   . LYS A 1 279 ? 8.050   -3.614  10.332  1.0 97.75 ? 279 LYS A C   1 O43570 UNP 279 K 
ATOM 2207 C CB  . LYS A 1 279 ? 9.857   -5.347  10.102  1.0 97.75 ? 279 LYS A CB  1 O43570 UNP 279 K 
ATOM 2208 O O   . LYS A 1 279 ? 8.430   -2.564  9.809   1.0 97.75 ? 279 LYS A O   1 O43570 UNP 279 K 
ATOM 2209 C CG  . LYS A 1 279 ? 10.164  -6.806  9.752   1.0 97.75 ? 279 LYS A CG  1 O43570 UNP 279 K 
ATOM 2210 C CD  . LYS A 1 279 ? 11.581  -7.148  10.211  1.0 97.75 ? 279 LYS A CD  1 O43570 UNP 279 K 
ATOM 2211 C CE  . LYS A 1 279 ? 11.874  -8.614  9.902   1.0 97.75 ? 279 LYS A CE  1 O43570 UNP 279 K 
ATOM 2212 N NZ  . LYS A 1 279 ? 13.258  -8.955  10.293  1.0 97.75 ? 279 LYS A NZ  1 O43570 UNP 279 K 
ATOM 2213 N N   . PHE A 1 280 ? 7.356   -3.658  11.464  1.0 96.97 ? 280 PHE A N   1 O43570 UNP 280 F 
ATOM 2214 C CA  . PHE A 1 280 ? 6.805   -2.489  12.146  1.0 96.97 ? 280 PHE A CA  1 O43570 UNP 280 F 
ATOM 2215 C C   . PHE A 1 280 ? 7.117   -2.530  13.647  1.0 96.97 ? 280 PHE A C   1 O43570 UNP 280 F 
ATOM 2216 C CB  . PHE A 1 280 ? 5.309   -2.384  11.833  1.0 96.97 ? 280 PHE A CB  1 O43570 UNP 280 F 
ATOM 2217 O O   . PHE A 1 280 ? 6.235   -2.496  14.497  1.0 96.97 ? 280 PHE A O   1 O43570 UNP 280 F 
ATOM 2218 C CG  . PHE A 1 280 ? 4.708   -1.040  12.190  1.0 96.97 ? 280 PHE A CG  1 O43570 UNP 280 F 
ATOM 2219 C CD1 . PHE A 1 280 ? 4.009   -0.856  13.396  1.0 96.97 ? 280 PHE A CD1 1 O43570 UNP 280 F 
ATOM 2220 C CD2 . PHE A 1 280 ? 4.784   0.015   11.270  1.0 96.97 ? 280 PHE A CD2 1 O43570 UNP 280 F 
ATOM 2221 C CE1 . PHE A 1 280 ? 3.384   0.370   13.673  1.0 96.97 ? 280 PHE A CE1 1 O43570 UNP 280 F 
ATOM 2222 C CE2 . PHE A 1 280 ? 4.078   1.205   11.508  1.0 96.97 ? 280 PHE A CE2 1 O43570 UNP 280 F 
ATOM 2223 C CZ  . PHE A 1 280 ? 3.407   1.403   12.724  1.0 96.97 ? 280 PHE A CZ  1 O43570 UNP 280 F 
ATOM 2224 N N   . ASP A 1 281 ? 8.399   -2.627  13.978  1.0 88.44 ? 281 ASP A N   1 O43570 UNP 281 D 
ATOM 2225 C CA  . ASP A 1 281 ? 8.830   -2.723  15.372  1.0 88.44 ? 281 ASP A CA  1 O43570 UNP 281 D 
ATOM 2226 C C   . ASP A 1 281 ? 8.857   -1.331  16.033  1.0 88.44 ? 281 ASP A C   1 O43570 UNP 281 D 
ATOM 2227 C CB  . ASP A 1 281 ? 10.179  -3.457  15.462  1.0 88.44 ? 281 ASP A CB  1 O43570 UNP 281 D 
ATOM 2228 O O   . ASP A 1 281 ? 9.163   -0.331  15.379  1.0 88.44 ? 281 ASP A O   1 O43570 UNP 281 D 
ATOM 2229 C CG  . ASP A 1 281 ? 10.151  -4.893  14.905  1.0 88.44 ? 281 ASP A CG  1 O43570 UNP 281 D 
ATOM 2230 O OD1 . ASP A 1 281 ? 9.052   -5.467  14.750  1.0 88.44 ? 281 ASP A OD1 1 O43570 UNP 281 D 
ATOM 2231 O OD2 . ASP A 1 281 ? 11.246  -5.407  14.574  1.0 88.44 ? 281 ASP A OD2 1 O43570 UNP 281 D 
ATOM 2232 N N   . GLU A 1 282 ? 8.539   -1.273  17.332  1.0 93.38 ? 282 GLU A N   1 O43570 UNP 282 E 
ATOM 2233 C CA  . GLU A 1 282 ? 8.595   -0.068  18.189  1.0 93.38 ? 282 GLU A CA  1 O43570 UNP 282 E 
ATOM 2234 C C   . GLU A 1 282 ? 7.758   1.128   17.702  1.0 93.38 ? 282 GLU A C   1 O43570 UNP 282 E 
ATOM 2235 C CB  . GLU A 1 282 ? 10.045  0.333   18.495  1.0 93.38 ? 282 GLU A CB  1 O43570 UNP 282 E 
ATOM 2236 O O   . GLU A 1 282 ? 8.064   2.294   17.967  1.0 93.38 ? 282 GLU A O   1 O43570 UNP 282 E 
ATOM 2237 C CG  . GLU A 1 282 ? 10.854  -0.797  19.144  1.0 93.38 ? 282 GLU A CG  1 O43570 UNP 282 E 
ATOM 2238 C CD  . GLU A 1 282 ? 12.246  -0.333  19.598  1.0 93.38 ? 282 GLU A CD  1 O43570 UNP 282 E 
ATOM 2239 O OE1 . GLU A 1 282 ? 12.830  -1.041  20.450  1.0 93.38 ? 282 GLU A OE1 1 O43570 UNP 282 E 
ATOM 2240 O OE2 . GLU A 1 282 ? 12.731  0.714   19.108  1.0 93.38 ? 282 GLU A OE2 1 O43570 UNP 282 E 
ATOM 2241 N N   . ARG A 1 283 ? 6.676   0.853   16.976  1.0 97.37 ? 283 ARG A N   1 O43570 UNP 283 R 
ATOM 2242 C CA  . ARG A 1 283 ? 5.781   1.871   16.430  1.0 97.37 ? 283 ARG A CA  1 O43570 UNP 283 R 
ATOM 2243 C C   . ARG A 1 283 ? 4.337   1.516   16.734  1.0 97.37 ? 283 ARG A C   1 O43570 UNP 283 R 
ATOM 2244 C CB  . ARG A 1 283 ? 6.042   2.002   14.929  1.0 97.37 ? 283 ARG A CB  1 O43570 UNP 283 R 
ATOM 2245 O O   . ARG A 1 283 ? 3.992   0.357   16.931  1.0 97.37 ? 283 ARG A O   1 O43570 UNP 283 R 
ATOM 2246 C CG  . ARG A 1 283 ? 7.450   2.547   14.630  1.0 97.37 ? 283 ARG A CG  1 O43570 UNP 283 R 
ATOM 2247 C CD  . ARG A 1 283 ? 7.745   2.462   13.136  1.0 97.37 ? 283 ARG A CD  1 O43570 UNP 283 R 
ATOM 2248 N NE  . ARG A 1 283 ? 6.801   3.319   12.420  1.0 97.37 ? 283 ARG A NE  1 O43570 UNP 283 R 
ATOM 2249 N NH1 . ARG A 1 283 ? 6.831   2.327   10.334  1.0 97.37 ? 283 ARG A NH1 1 O43570 UNP 283 R 
ATOM 2250 N NH2 . ARG A 1 283 ? 5.424   3.994   10.848  1.0 97.37 ? 283 ARG A NH2 1 O43570 UNP 283 R 
ATOM 2251 C CZ  . ARG A 1 283 ? 6.369   3.193   11.193  1.0 97.37 ? 283 ARG A CZ  1 O43570 UNP 283 R 
ATOM 2252 N N   . LEU A 1 284 ? 3.494   2.540   16.749  1.0 97.76 ? 284 LEU A N   1 O43570 UNP 284 L 
ATOM 2253 C CA  . LEU A 1 284 ? 2.060   2.398   16.951  1.0 97.76 ? 284 LEU A CA  1 O43570 UNP 284 L 
ATOM 2254 C C   . LEU A 1 284 ? 1.309   2.791   15.687  1.0 97.76 ? 284 LEU A C   1 O43570 UNP 284 L 
ATOM 2255 C CB  . LEU A 1 284 ? 1.614   3.235   18.157  1.0 97.76 ? 284 LEU A CB  1 O43570 UNP 284 L 
ATOM 2256 O O   . LEU A 1 284 ? 1.736   3.669   14.928  1.0 97.76 ? 284 LEU A O   1 O43570 UNP 284 L 
ATOM 2257 C CG  . LEU A 1 284 ? 2.225   2.779   19.495  1.0 97.76 ? 284 LEU A CG  1 O43570 UNP 284 L 
ATOM 2258 C CD1 . LEU A 1 284 ? 1.843   3.801   20.558  1.0 97.76 ? 284 LEU A CD1 1 O43570 UNP 284 L 
ATOM 2259 C CD2 . LEU A 1 284 ? 1.727   1.398   19.924  1.0 97.76 ? 284 LEU A CD2 1 O43570 UNP 284 L 
ATOM 2260 N N   . VAL A 1 285 ? 0.166   2.151   15.502  1.0 98.62 ? 285 VAL A N   1 O43570 UNP 285 V 
ATOM 2261 C CA  . VAL A 1 285 ? -0.866  2.572   14.567  1.0 98.62 ? 285 VAL A CA  1 O43570 UNP 285 V 
ATOM 2262 C C   . VAL A 1 285 ? -1.972  3.216   15.387  1.0 98.62 ? 285 VAL A C   1 O43570 UNP 285 V 
ATOM 2263 C CB  . VAL A 1 285 ? -1.379  1.378   13.760  1.0 98.62 ? 285 VAL A CB  1 O43570 UNP 285 V 
ATOM 2264 O O   . VAL A 1 285 ? -2.556  2.596   16.275  1.0 98.62 ? 285 VAL A O   1 O43570 UNP 285 V 
ATOM 2265 C CG1 . VAL A 1 285 ? -2.577  1.763   12.888  1.0 98.62 ? 285 VAL A CG1 1 O43570 UNP 285 V 
ATOM 2266 C CG2 . VAL A 1 285 ? -0.288  0.805   12.853  1.0 98.62 ? 285 VAL A CG2 1 O43570 UNP 285 V 
ATOM 2267 N N   . TYR A 1 286 ? -2.274  4.472   15.088  1.0 98.54 ? 286 TYR A N   1 O43570 UNP 286 Y 
ATOM 2268 C CA  . TYR A 1 286 ? -3.347  5.181   15.766  1.0 98.54 ? 286 TYR A CA  1 O43570 UNP 286 Y 
ATOM 2269 C C   . TYR A 1 286 ? -4.695  4.815   15.144  1.0 98.54 ? 286 TYR A C   1 O43570 UNP 286 Y 
ATOM 2270 C CB  . TYR A 1 286 ? -3.071  6.681   15.772  1.0 98.54 ? 286 TYR A CB  1 O43570 UNP 286 Y 
ATOM 2271 O O   . TYR A 1 286 ? -4.786  4.582   13.941  1.0 98.54 ? 286 TYR A O   1 O43570 UNP 286 Y 
ATOM 2272 C CG  . TYR A 1 286 ? -1.768  7.037   16.453  1.0 98.54 ? 286 TYR A CG  1 O43570 UNP 286 Y 
ATOM 2273 C CD1 . TYR A 1 286 ? -1.699  7.073   17.859  1.0 98.54 ? 286 TYR A CD1 1 O43570 UNP 286 Y 
ATOM 2274 C CD2 . TYR A 1 286 ? -0.620  7.297   15.681  1.0 98.54 ? 286 TYR A CD2 1 O43570 UNP 286 Y 
ATOM 2275 C CE1 . TYR A 1 286 ? -0.489  7.397   18.498  1.0 98.54 ? 286 TYR A CE1 1 O43570 UNP 286 Y 
ATOM 2276 C CE2 . TYR A 1 286 ? 0.593   7.620   16.316  1.0 98.54 ? 286 TYR A CE2 1 O43570 UNP 286 Y 
ATOM 2277 O OH  . TYR A 1 286 ? 1.830   7.999   18.330  1.0 98.54 ? 286 TYR A OH  1 O43570 UNP 286 Y 
ATOM 2278 C CZ  . TYR A 1 286 ? 0.657   7.679   17.723  1.0 98.54 ? 286 TYR A CZ  1 O43570 UNP 286 Y 
ATOM 2279 N N   . THR A 1 287 ? -5.748  4.761   15.948  1.0 98.62 ? 287 THR A N   1 O43570 UNP 287 T 
ATOM 2280 C CA  . THR A 1 287 ? -7.108  4.423   15.505  1.0 98.62 ? 287 THR A CA  1 O43570 UNP 287 T 
ATOM 2281 C C   . THR A 1 287 ? -8.073  5.528   15.905  1.0 98.62 ? 287 THR A C   1 O43570 UNP 287 T 
ATOM 2282 C CB  . THR A 1 287 ? -7.569  3.060   16.052  1.0 98.62 ? 287 THR A CB  1 O43570 UNP 287 T 
ATOM 2283 O O   . THR A 1 287 ? -8.010  6.025   17.028  1.0 98.62 ? 287 THR A O   1 O43570 UNP 287 T 
ATOM 2284 C CG2 . THR A 1 287 ? -6.798  1.908   15.416  1.0 98.62 ? 287 THR A CG2 1 O43570 UNP 287 T 
ATOM 2285 O OG1 . THR A 1 287 ? -7.345  2.959   17.436  1.0 98.62 ? 287 THR A OG1 1 O43570 UNP 287 T 
ATOM 2286 N N   . SER A 1 288 ? -8.968  5.919   14.996  1.0 98.18 ? 288 SER A N   1 O43570 UNP 288 S 
ATOM 2287 C CA  . SER A 1 288 ? -10.038 6.898   15.270  1.0 98.18 ? 288 SER A CA  1 O43570 UNP 288 S 
ATOM 2288 C C   . SER A 1 288 ? -11.257 6.284   15.966  1.0 98.18 ? 288 SER A C   1 O43570 UNP 288 S 
ATOM 2289 C CB  . SER A 1 288 ? -10.488 7.544   13.965  1.0 98.18 ? 288 SER A CB  1 O43570 UNP 288 S 
ATOM 2290 O O   . SER A 1 288 ? -12.203 6.978   16.332  1.0 98.18 ? 288 SER A O   1 O43570 UNP 288 S 
ATOM 2291 O OG  . SER A 1 288 ? -11.067 6.550   13.150  1.0 98.18 ? 288 SER A OG  1 O43570 UNP 288 S 
ATOM 2292 N N   . PHE A 1 289 ? -11.245 4.968   16.153  1.0 97.27 ? 289 PHE A N   1 O43570 UNP 289 F 
ATOM 2293 C CA  . PHE A 1 289 ? -12.282 4.196   16.815  1.0 97.27 ? 289 PHE A CA  1 O43570 UNP 289 F 
ATOM 2294 C C   . PHE A 1 289 ? -11.673 3.491   18.020  1.0 97.27 ? 289 PHE A C   1 O43570 UNP 289 F 
ATOM 2295 C CB  . PHE A 1 289 ? -12.907 3.213   15.815  1.0 97.27 ? 289 PHE A CB  1 O43570 UNP 289 F 
ATOM 2296 O O   . PHE A 1 289 ? -10.579 2.930   17.943  1.0 97.27 ? 289 PHE A O   1 O43570 UNP 289 F 
ATOM 2297 C CG  . PHE A 1 289 ? -11.914 2.273   15.155  1.0 97.27 ? 289 PHE A CG  1 O43570 UNP 289 F 
ATOM 2298 C CD1 . PHE A 1 289 ? -11.221 2.682   14.000  1.0 97.27 ? 289 PHE A CD1 1 O43570 UNP 289 F 
ATOM 2299 C CD2 . PHE A 1 289 ? -11.645 1.013   15.723  1.0 97.27 ? 289 PHE A CD2 1 O43570 UNP 289 F 
ATOM 2300 C CE1 . PHE A 1 289 ? -10.269 1.834   13.411  1.0 97.27 ? 289 PHE A CE1 1 O43570 UNP 289 F 
ATOM 2301 C CE2 . PHE A 1 289 ? -10.684 0.168   15.140  1.0 97.27 ? 289 PHE A CE2 1 O43570 UNP 289 F 
ATOM 2302 C CZ  . PHE A 1 289 ? -10.003 0.581   13.983  1.0 97.27 ? 289 PHE A CZ  1 O43570 UNP 289 F 
ATOM 2303 N N   . SER A 1 290 ? -12.377 3.496   19.147  1.0 89.38 ? 290 SER A N   1 O43570 UNP 290 S 
ATOM 2304 C CA  . SER A 1 290 ? -11.962 2.679   20.275  1.0 89.38 ? 290 SER A CA  1 O43570 UNP 290 S 
ATOM 2305 C C   . SER A 1 290 ? -12.315 1.225   19.983  1.0 89.38 ? 290 SER A C   1 O43570 UNP 290 S 
ATOM 2306 C CB  . SER A 1 290 ? -12.554 3.193   21.590  1.0 89.38 ? 290 SER A CB  1 O43570 UNP 290 S 
ATOM 2307 O O   . SER A 1 290 ? -13.440 0.892   19.600  1.0 89.38 ? 290 SER A O   1 O43570 UNP 290 S 
ATOM 2308 O OG  . SER A 1 290 ? -13.966 3.259   21.544  1.0 89.38 ? 290 SER A OG  1 O43570 UNP 290 S 
ATOM 2309 N N   . GLN A 1 291 ? -11.357 0.322   20.178  1.0 67.62 ? 291 GLN A N   1 O43570 UNP 291 Q 
ATOM 2310 C CA  . GLN A 1 291 ? -11.728 -1.068  20.377  1.0 67.62 ? 291 GLN A CA  1 O43570 UNP 291 Q 
ATOM 2311 C C   . GLN A 1 291 ? -12.467 -1.114  21.709  1.0 67.62 ? 291 GLN A C   1 O43570 UNP 291 Q 
ATOM 2312 C CB  . GLN A 1 291 ? -10.501 -1.988  20.350  1.0 67.62 ? 291 GLN A CB  1 O43570 UNP 291 Q 
ATOM 2313 O O   . GLN A 1 291 ? -11.880 -0.823  22.753  1.0 67.62 ? 291 GLN A O   1 O43570 UNP 291 Q 
ATOM 2314 C CG  . GLN A 1 291 ? -9.850  -2.006  18.957  1.0 67.62 ? 291 GLN A CG  1 O43570 UNP 291 Q 
ATOM 2315 C CD  . GLN A 1 291 ? -8.858  -3.149  18.783  1.0 67.62 ? 291 GLN A CD  1 O43570 UNP 291 Q 
ATOM 2316 N NE2 . GLN A 1 291 ? -8.438  -3.418  17.571  1.0 67.62 ? 291 GLN A NE2 1 O43570 UNP 291 Q 
ATOM 2317 O OE1 . GLN A 1 291 ? -8.476  -3.849  19.702  1.0 67.62 ? 291 GLN A OE1 1 O43570 UNP 291 Q 
ATOM 2318 N N   . VAL A 1 292 ? -13.763 -1.435  21.691  1.0 54.66 ? 292 VAL A N   1 O43570 UNP 292 V 
ATOM 2319 C CA  . VAL A 1 292 ? -14.438 -1.865  22.915  1.0 54.66 ? 292 VAL A CA  1 O43570 UNP 292 V 
ATOM 2320 C C   . VAL A 1 292 ? -13.750 -3.159  23.308  1.0 54.66 ? 292 VAL A C   1 O43570 UNP 292 V 
ATOM 2321 C CB  . VAL A 1 292 ? -15.960 -2.047  22.756  1.0 54.66 ? 292 VAL A CB  1 O43570 UNP 292 V 
ATOM 2322 O O   . VAL A 1 292 ? -14.101 -4.243  22.846  1.0 54.66 ? 292 VAL A O   1 O43570 UNP 292 V 
ATOM 2323 C CG1 . VAL A 1 292 ? -16.599 -2.494  24.081  1.0 54.66 ? 292 VAL A CG1 1 O43570 UNP 292 V 
ATOM 2324 C CG2 . VAL A 1 292 ? -16.626 -0.731  22.338  1.0 54.66 ? 292 VAL A CG2 1 O43570 UNP 292 V 
ATOM 2325 N N   . GLN A 1 293 ? -12.712 -3.034  24.125  1.0 45.92 ? 293 GLN A N   1 O43570 UNP 293 Q 
ATOM 2326 C CA  . GLN A 1 293 ? -12.146 -4.149  24.835  1.0 45.92 ? 293 GLN A CA  1 O43570 UNP 293 Q 
ATOM 2327 C C   . GLN A 1 293 ? -13.282 -4.597  25.743  1.0 45.92 ? 293 GLN A C   1 O43570 UNP 293 Q 
ATOM 2328 C CB  . GLN A 1 293 ? -10.861 -3.686  25.545  1.0 45.92 ? 293 GLN A CB  1 O43570 UNP 293 Q 
ATOM 2329 O O   . GLN A 1 293 ? -13.565 -3.979  26.772  1.0 45.92 ? 293 GLN A O   1 O43570 UNP 293 Q 
ATOM 2330 C CG  . GLN A 1 293 ? -9.831  -4.808  25.744  1.0 45.92 ? 293 GLN A CG  1 O43570 UNP 293 Q 
ATOM 2331 C CD  . GLN A 1 293 ? -8.442  -4.259  26.079  1.0 45.92 ? 293 GLN A CD  1 O43570 UNP 293 Q 
ATOM 2332 N NE2 . GLN A 1 293 ? -7.434  -5.098  26.171  1.0 45.92 ? 293 GLN A NE2 1 O43570 UNP 293 Q 
ATOM 2333 O OE1 . GLN A 1 293 ? -8.223  -3.074  26.258  1.0 45.92 ? 293 GLN A OE1 1 O43570 UNP 293 Q 
ATOM 2334 N N   . VAL A 1 294 ? -14.011 -5.631  25.320  1.0 34.55 ? 294 VAL A N   1 O43570 UNP 294 V 
ATOM 2335 C CA  . VAL A 1 294 ? -14.801 -6.410  26.258  1.0 34.55 ? 294 VAL A CA  1 O43570 UNP 294 V 
ATOM 2336 C C   . VAL A 1 294 ? -13.753 -7.015  27.175  1.0 34.55 ? 294 VAL A C   1 O43570 UNP 294 V 
ATOM 2337 C CB  . VAL A 1 294 ? -15.696 -7.471  25.587  1.0 34.55 ? 294 VAL A CB  1 O43570 UNP 294 V 
ATOM 2338 O O   . VAL A 1 294 ? -13.225 -8.094  26.925  1.0 34.55 ? 294 VAL A O   1 O43570 UNP 294 V 
ATOM 2339 C CG1 . VAL A 1 294 ? -16.563 -8.176  26.641  1.0 34.55 ? 294 VAL A CG1 1 O43570 UNP 294 V 
ATOM 2340 C CG2 . VAL A 1 294 ? -16.645 -6.840  24.561  1.0 34.55 ? 294 VAL A CG2 1 O43570 UNP 294 V 
ATOM 2341 N N   . CYS A 1 295 ? -13.393 -6.275  28.220  1.0 36.64 ? 295 CYS A N   1 O43570 UNP 295 C 
ATOM 2342 C CA  . CYS A 1 295 ? -12.783 -6.830  29.400  1.0 36.64 ? 295 CYS A CA  1 O43570 UNP 295 C 
ATOM 2343 C C   . CYS A 1 295 ? -13.830 -7.786  29.969  1.0 36.64 ? 295 CYS A C   1 O43570 UNP 295 C 
ATOM 2344 C CB  . CYS A 1 295 ? -12.400 -5.702  30.374  1.0 36.64 ? 295 CYS A CB  1 O43570 UNP 295 C 
ATOM 2345 O O   . CYS A 1 295 ? -14.573 -7.447  30.888  1.0 36.64 ? 295 CYS A O   1 O43570 UNP 295 C 
ATOM 2346 S SG  . CYS A 1 295 ? -10.943 -4.811  29.757  1.0 36.64 ? 295 CYS A SG  1 O43570 UNP 295 C 
ATOM 2347 N N   . THR A 1 296 ? -13.911 -9.001  29.420  1.0 35.54 ? 296 THR A N   1 O43570 UNP 296 T 
ATOM 2348 C CA  . THR A 1 296 ? -14.255 -10.148 30.243  1.0 35.54 ? 296 THR A CA  1 O43570 UNP 296 T 
ATOM 2349 C C   . THR A 1 296 ? -13.166 -10.153 31.299  1.0 35.54 ? 296 THR A C   1 O43570 UNP 296 T 
ATOM 2350 C CB  . THR A 1 296 ? -14.288 -11.471 29.459  1.0 35.54 ? 296 THR A CB  1 O43570 UNP 296 T 
ATOM 2351 O O   . THR A 1 296 ? -12.022 -10.519 31.024  1.0 35.54 ? 296 THR A O   1 O43570 UNP 296 T 
ATOM 2352 C CG2 . THR A 1 296 ? -15.416 -11.498 28.429  1.0 35.54 ? 296 THR A CG2 1 O43570 UNP 296 T 
ATOM 2353 O OG1 . THR A 1 296 ? -13.083 -11.678 28.763  1.0 35.54 ? 296 THR A OG1 1 O43570 UNP 296 T 
ATOM 2354 N N   . ALA A 1 297 ? -13.467 -9.581  32.463  1.0 40.16 ? 297 ALA A N   1 O43570 UNP 297 A 
ATOM 2355 C CA  . ALA A 1 297 ? -12.604 -9.677  33.619  1.0 40.16 ? 297 ALA A CA  1 O43570 UNP 297 A 
ATOM 2356 C C   . ALA A 1 297 ? -12.282 -11.170 33.796  1.0 40.16 ? 297 ALA A C   1 O43570 UNP 297 A 
ATOM 2357 C CB  . ALA A 1 297 ? -13.336 -9.060  34.817  1.0 40.16 ? 297 ALA A CB  1 O43570 UNP 297 A 
ATOM 2358 O O   . ALA A 1 297 ? -13.175 -11.955 34.103  1.0 40.16 ? 297 ALA A O   1 O43570 UNP 297 A 
ATOM 2359 N N   . ALA A 1 298 ? -11.026 -11.532 33.513  1.0 45.22 ? 298 ALA A N   1 O43570 UNP 298 A 
ATOM 2360 C CA  . ALA A 1 298 ? -10.539 -12.894 33.290  1.0 45.22 ? 298 ALA A CA  1 O43570 UNP 298 A 
ATOM 2361 C C   . ALA A 1 298 ? -11.157 -13.601 32.062  1.0 45.22 ? 298 ALA A C   1 O43570 UNP 298 A 
ATOM 2362 C CB  . ALA A 1 298 ? -10.659 -13.700 34.590  1.0 45.22 ? 298 ALA A CB  1 O43570 UNP 298 A 
ATOM 2363 O O   . ALA A 1 298 ? -12.357 -13.529 31.828  1.0 45.22 ? 298 ALA A O   1 O43570 UNP 298 A 
ATOM 2364 N N   . GLY A 1 299 ? -10.329 -14.307 31.282  1.0 50.19 ? 299 GLY A N   1 O43570 UNP 299 G 
ATOM 2365 C CA  . GLY A 1 299 ? -10.683 -15.083 30.080  1.0 50.19 ? 299 GLY A CA  1 O43570 UNP 299 G 
ATOM 2366 C C   . GLY A 1 299 ? -11.652 -16.252 30.308  1.0 50.19 ? 299 GLY A C   1 O43570 UNP 299 G 
ATOM 2367 O O   . GLY A 1 299 ? -11.349 -17.401 29.999  1.0 50.19 ? 299 GLY A O   1 O43570 UNP 299 G 
ATOM 2368 N N   . LEU A 1 300 ? -12.826 -15.967 30.853  1.0 57.42 ? 300 LEU A N   1 O43570 UNP 300 L 
ATOM 2369 C CA  . LEU A 1 300 ? -13.928 -16.888 31.030  1.0 57.42 ? 300 LEU A CA  1 O43570 UNP 300 L 
ATOM 2370 C C   . LEU A 1 300 ? -14.846 -16.695 29.822  1.0 57.42 ? 300 LEU A C   1 O43570 UNP 300 L 
ATOM 2371 C CB  . LEU A 1 300 ? -14.604 -16.590 32.385  1.0 57.42 ? 300 LEU A CB  1 O43570 UNP 300 L 
ATOM 2372 O O   . LEU A 1 300 ? -15.422 -15.624 29.638  1.0 57.42 ? 300 LEU A O   1 O43570 UNP 300 L 
ATOM 2373 C CG  . LEU A 1 300 ? -13.677 -16.836 33.595  1.0 57.42 ? 300 LEU A CG  1 O43570 UNP 300 L 
ATOM 2374 C CD1 . LEU A 1 300 ? -14.201 -16.116 34.835  1.0 57.42 ? 300 LEU A CD1 1 O43570 UNP 300 L 
ATOM 2375 C CD2 . LEU A 1 300 ? -13.538 -18.311 33.961  1.0 57.42 ? 300 LEU A CD2 1 O43570 UNP 300 L 
ATOM 2376 N N   . SER A 1 301 ? -14.970 -17.722 28.976  1.0 70.86 ? 301 SER A N   1 O43570 UNP 301 S 
ATOM 2377 C CA  . SER A 1 301 ? -15.949 -17.705 27.887  1.0 70.86 ? 301 SER A CA  1 O43570 UNP 301 S 
ATOM 2378 C C   . SER A 1 301 ? -17.348 -17.441 28.456  1.0 70.86 ? 301 SER A C   1 O43570 UNP 301 S 
ATOM 2379 C CB  . SER A 1 301 ? -15.901 -19.009 27.077  1.0 70.86 ? 301 SER A CB  1 O43570 UNP 301 S 
ATOM 2380 O O   . SER A 1 301 ? -17.624 -17.763 29.615  1.0 70.86 ? 301 SER A O   1 O43570 UNP 301 S 
ATOM 2381 O OG  . SER A 1 301 ? -16.505 -20.088 27.767  1.0 70.86 ? 301 SER A OG  1 O43570 UNP 301 S 
ATOM 2382 N N   . LEU A 1 302 ? -18.262 -16.893 27.651  1.0 72.85 ? 302 LEU A N   1 O43570 UNP 302 L 
ATOM 2383 C CA  . LEU A 1 302 ? -19.653 -16.678 28.074  1.0 72.85 ? 302 LEU A CA  1 O43570 UNP 302 L 
ATOM 2384 C C   . LEU A 1 302 ? -20.265 -17.957 28.681  1.0 72.85 ? 302 LEU A C   1 O43570 UNP 302 L 
ATOM 2385 C CB  . LEU A 1 302 ? -20.456 -16.199 26.851  1.0 72.85 ? 302 LEU A CB  1 O43570 UNP 302 L 
ATOM 2386 O O   . LEU A 1 302 ? -21.011 -17.887 29.654  1.0 72.85 ? 302 LEU A O   1 O43570 UNP 302 L 
ATOM 2387 C CG  . LEU A 1 302 ? -21.873 -15.695 27.186  1.0 72.85 ? 302 LEU A CG  1 O43570 UNP 302 L 
ATOM 2388 C CD1 . LEU A 1 302 ? -21.834 -14.348 27.911  1.0 72.85 ? 302 LEU A CD1 1 O43570 UNP 302 L 
ATOM 2389 C CD2 . LEU A 1 302 ? -22.672 -15.523 25.895  1.0 72.85 ? 302 LEU A CD2 1 O43570 UNP 302 L 
ATOM 2390 N N   . GLY A 1 303 ? -19.873 -19.128 28.164  1.0 75.33 ? 303 GLY A N   1 O43570 UNP 303 G 
ATOM 2391 C CA  . GLY A 1 303 ? -20.253 -20.431 28.709  1.0 75.33 ? 303 GLY A CA  1 O43570 UNP 303 G 
ATOM 2392 C C   . GLY A 1 303 ? -19.733 -20.698 30.126  1.0 75.33 ? 303 GLY A C   1 O43570 UNP 303 G 
ATOM 2393 O O   . GLY A 1 303 ? -20.446 -21.310 30.917  1.0 75.33 ? 303 GLY A O   1 O43570 UNP 303 G 
ATOM 2394 N N   . ILE A 1 304 ? -18.540 -20.211 30.482  1.0 78.11 ? 304 ILE A N   1 O43570 UNP 304 I 
ATOM 2395 C CA  . ILE A 1 304 ? -18.005 -20.326 31.845  1.0 78.11 ? 304 ILE A CA  1 O43570 UNP 304 I 
ATOM 2396 C C   . ILE A 1 304 ? -18.704 -19.350 32.802  1.0 78.11 ? 304 ILE A C   1 O43570 UNP 304 I 
ATOM 2397 C CB  . ILE A 1 304 ? -16.468 -20.186 31.898  1.0 78.11 ? 304 ILE A CB  1 O43570 UNP 304 I 
ATOM 2398 O O   . ILE A 1 304 ? -19.010 -19.709 33.936  1.0 78.11 ? 304 ILE A O   1 O43570 UNP 304 I 
ATOM 2399 C CG1 . ILE A 1 304 ? -15.754 -21.222 31.001  1.0 78.11 ? 304 ILE A CG1 1 O43570 UNP 304 I 
ATOM 2400 C CG2 . ILE A 1 304 ? -16.040 -20.420 33.358  1.0 78.11 ? 304 ILE A CG2 1 O43570 UNP 304 I 
ATOM 2401 C CD1 . ILE A 1 304 ? -14.257 -20.951 30.791  1.0 78.11 ? 304 ILE A CD1 1 O43570 UNP 304 I 
ATOM 2402 N N   . ILE A 1 305 ? -19.028 -18.135 32.353  1.0 76.68 ? 305 ILE A N   1 O43570 UNP 305 I 
ATOM 2403 C CA  . ILE A 1 305 ? -19.815 -17.195 33.170  1.0 76.68 ? 305 ILE A CA  1 O43570 UNP 305 I 
ATOM 2404 C C   . ILE A 1 305 ? -21.200 -17.789 33.458  1.0 76.68 ? 305 ILE A C   1 O43570 UNP 305 I 
ATOM 2405 C CB  . ILE A 1 305 ? -19.912 -15.811 32.490  1.0 76.68 ? 305 ILE A CB  1 O43570 UNP 305 I 
ATOM 2406 O O   . ILE A 1 305 ? -21.650 -17.790 34.606  1.0 76.68 ? 305 ILE A O   1 O43570 UNP 305 I 
ATOM 2407 C CG1 . ILE A 1 305 ? -18.498 -15.210 32.308  1.0 76.68 ? 305 ILE A CG1 1 O43570 UNP 305 I 
ATOM 2408 C CG2 . ILE A 1 305 ? -20.806 -14.866 33.318  1.0 76.68 ? 305 ILE A CG2 1 O43570 UNP 305 I 
ATOM 2409 C CD1 . ILE A 1 305 ? -18.472 -13.887 31.534  1.0 76.68 ? 305 ILE A CD1 1 O43570 UNP 305 I 
ATOM 2410 N N   . LEU A 1 306 ? -21.852 -18.356 32.436  1.0 82.73 ? 306 LEU A N   1 O43570 UNP 306 L 
ATOM 2411 C CA  . LEU A 1 306 ? -23.155 -18.998 32.589  1.0 82.73 ? 306 LEU A CA  1 O43570 UNP 306 L 
ATOM 2412 C C   . LEU A 1 306 ? -23.087 -20.214 33.522  1.0 82.73 ? 306 LEU A C   1 O43570 UNP 306 L 
ATOM 2413 C CB  . LEU A 1 306 ? -23.711 -19.410 31.210  1.0 82.73 ? 306 LEU A CB  1 O43570 UNP 306 L 
ATOM 2414 O O   . LEU A 1 306 ? -23.976 -20.397 34.352  1.0 82.73 ? 306 LEU A O   1 O43570 UNP 306 L 
ATOM 2415 C CG  . LEU A 1 306 ? -25.192 -19.029 31.053  1.0 82.73 ? 306 LEU A CG  1 O43570 UNP 306 L 
ATOM 2416 C CD1 . LEU A 1 306 ? -25.321 -17.577 30.582  1.0 82.73 ? 306 LEU A CD1 1 O43570 UNP 306 L 
ATOM 2417 C CD2 . LEU A 1 306 ? -25.875 -19.934 30.030  1.0 82.73 ? 306 LEU A CD2 1 O43570 UNP 306 L 
ATOM 2418 N N   . SER A 1 307 ? -22.038 -21.034 33.418  1.0 85.27 ? 307 SER A N   1 O43570 UNP 307 S 
ATOM 2419 C CA  . SER A 1 307 ? -21.882 -22.217 34.267  1.0 85.27 ? 307 SER A CA  1 O43570 UNP 307 S 
ATOM 2420 C C   . SER A 1 307 ? -21.584 -21.856 35.723  1.0 85.27 ? 307 SER A C   1 O43570 UNP 307 S 
ATOM 2421 C CB  . SER A 1 307 ? -20.835 -23.171 33.691  1.0 85.27 ? 307 SER A CB  1 O43570 UNP 307 S 
ATOM 2422 O O   . SER A 1 307 ? -22.153 -22.479 36.618  1.0 85.27 ? 307 SER A O   1 O43570 UNP 307 S 
ATOM 2423 O OG  . SER A 1 307 ? -19.549 -22.604 33.715  1.0 85.27 ? 307 SER A OG  1 O43570 UNP 307 S 
ATOM 2424 N N   . LEU A 1 308 ? -20.794 -20.808 35.984  1.0 87.01 ? 308 LEU A N   1 O43570 UNP 308 L 
ATOM 2425 C CA  . LEU A 1 308 ? -20.579 -20.275 37.334  1.0 87.01 ? 308 LEU A CA  1 O43570 UNP 308 L 
ATOM 2426 C C   . LEU A 1 308 ? -21.862 -19.677 37.922  1.0 87.01 ? 308 LEU A C   1 O43570 UNP 308 L 
ATOM 2427 C CB  . LEU A 1 308 ? -19.457 -19.222 37.309  1.0 87.01 ? 308 LEU A CB  1 O43570 UNP 308 L 
ATOM 2428 O O   . LEU A 1 308 ? -22.169 -19.922 39.089  1.0 87.01 ? 308 LEU A O   1 O43570 UNP 308 L 
ATOM 2429 C CG  . LEU A 1 308 ? -18.042 -19.794 37.104  1.0 87.01 ? 308 LEU A CG  1 O43570 UNP 308 L 
ATOM 2430 C CD1 . LEU A 1 308 ? -17.052 -18.639 36.941  1.0 87.01 ? 308 LEU A CD1 1 O43570 UNP 308 L 
ATOM 2431 C CD2 . LEU A 1 308 ? -17.586 -20.649 38.290  1.0 87.01 ? 308 LEU A CD2 1 O43570 UNP 308 L 
ATOM 2432 N N   . ALA A 1 309 ? -22.643 -18.948 37.121  1.0 87.18 ? 309 ALA A N   1 O43570 UNP 309 A 
ATOM 2433 C CA  . ALA A 1 309 ? -23.934 -18.415 37.550  1.0 87.18 ? 309 ALA A CA  1 O43570 UNP 309 A 
ATOM 2434 C C   . ALA A 1 309 ? -24.925 -19.543 37.892  1.0 87.18 ? 309 ALA A C   1 O43570 UNP 309 A 
ATOM 2435 C CB  . ALA A 1 309 ? -24.473 -17.485 36.458  1.0 87.18 ? 309 ALA A CB  1 O43570 UNP 309 A 
ATOM 2436 O O   . ALA A 1 309 ? -25.550 -19.518 38.952  1.0 87.18 ? 309 ALA A O   1 O43570 UNP 309 A 
ATOM 2437 N N   . LEU A 1 310 ? -25.018 -20.572 37.043  1.0 90.23 ? 310 LEU A N   1 O43570 UNP 310 L 
ATOM 2438 C CA  . LEU A 1 310 ? -25.849 -21.755 37.285  1.0 90.23 ? 310 LEU A CA  1 O43570 UNP 310 L 
ATOM 2439 C C   . LEU A 1 310 ? -25.389 -22.536 38.523  1.0 90.23 ? 310 LEU A C   1 O43570 UNP 310 L 
ATOM 2440 C CB  . LEU A 1 310 ? -25.833 -22.657 36.038  1.0 90.23 ? 310 LEU A CB  1 O43570 UNP 310 L 
ATOM 2441 O O   . LEU A 1 310 ? -26.226 -22.927 39.335  1.0 90.23 ? 310 LEU A O   1 O43570 UNP 310 L 
ATOM 2442 C CG  . LEU A 1 310 ? -26.721 -22.145 34.889  1.0 90.23 ? 310 LEU A CG  1 O43570 UNP 310 L 
ATOM 2443 C CD1 . LEU A 1 310 ? -26.371 -22.881 33.595  1.0 90.23 ? 310 LEU A CD1 1 O43570 UNP 310 L 
ATOM 2444 C CD2 . LEU A 1 310 ? -28.206 -22.380 35.183  1.0 90.23 ? 310 LEU A CD2 1 O43570 UNP 310 L 
ATOM 2445 N N   . ALA A 1 311 ? -24.080 -22.723 38.709  1.0 91.21 ? 311 ALA A N   1 O43570 UNP 311 A 
ATOM 2446 C CA  . ALA A 1 311 ? -23.524 -23.370 39.895  1.0 91.21 ? 311 ALA A CA  1 O43570 UNP 311 A 
ATOM 2447 C C   . ALA A 1 311 ? -23.820 -22.568 41.174  1.0 91.21 ? 311 ALA A C   1 O43570 UNP 311 A 
ATOM 2448 C CB  . ALA A 1 311 ? -22.018 -23.570 39.691  1.0 91.21 ? 311 ALA A CB  1 O43570 UNP 311 A 
ATOM 2449 O O   . ALA A 1 311 ? -24.173 -23.154 42.198  1.0 91.21 ? 311 ALA A O   1 O43570 UNP 311 A 
ATOM 2450 N N   . GLY A 1 312 ? -23.747 -21.235 41.106  1.0 90.33 ? 312 GLY A N   1 O43570 UNP 312 G 
ATOM 2451 C CA  . GLY A 1 312 ? -24.117 -20.341 42.202  1.0 90.33 ? 312 GLY A CA  1 O43570 UNP 312 G 
ATOM 2452 C C   . GLY A 1 312 ? -25.596 -20.453 42.574  1.0 90.33 ? 312 GLY A C   1 O43570 UNP 312 G 
ATOM 2453 O O   . GLY A 1 312 ? -25.924 -20.636 43.747  1.0 90.33 ? 312 GLY A O   1 O43570 UNP 312 G 
ATOM 2454 N N   . ILE A 1 313 ? -26.492 -20.426 41.581  1.0 91.99 ? 313 ILE A N   1 O43570 UNP 313 I 
ATOM 2455 C CA  . ILE A 1 313 ? -27.938 -20.602 41.790  1.0 91.99 ? 313 ILE A CA  1 O43570 UNP 313 I 
ATOM 2456 C C   . ILE A 1 313 ? -28.228 -21.981 42.392  1.0 91.99 ? 313 ILE A C   1 O43570 UNP 313 I 
ATOM 2457 C CB  . ILE A 1 313 ? -28.713 -20.370 40.470  1.0 91.99 ? 313 ILE A CB  1 O43570 UNP 313 I 
ATOM 2458 O O   . ILE A 1 313 ? -28.949 -22.075 43.385  1.0 91.99 ? 313 ILE A O   1 O43570 UNP 313 I 
ATOM 2459 C CG1 . ILE A 1 313 ? -28.616 -18.885 40.046  1.0 91.99 ? 313 ILE A CG1 1 O43570 UNP 313 I 
ATOM 2460 C CG2 . ILE A 1 313 ? -30.196 -20.768 40.616  1.0 91.99 ? 313 ILE A CG2 1 O43570 UNP 313 I 
ATOM 2461 C CD1 . ILE A 1 313 ? -29.052 -18.627 38.598  1.0 91.99 ? 313 ILE A CD1 1 O43570 UNP 313 I 
ATOM 2462 N N   . LEU A 1 314 ? -27.625 -23.045 41.852  1.0 92.43 ? 314 LEU A N   1 O43570 UNP 314 L 
ATOM 2463 C CA  . LEU A 1 314 ? -27.801 -24.403 42.366  1.0 92.43 ? 314 LEU A CA  1 O43570 UNP 314 L 
ATOM 2464 C C   . LEU A 1 314 ? -27.301 -24.522 43.815  1.0 92.43 ? 314 LEU A C   1 O43570 UNP 314 L 
ATOM 2465 C CB  . LEU A 1 314 ? -27.078 -25.392 41.433  1.0 92.43 ? 314 LEU A CB  1 O43570 UNP 314 L 
ATOM 2466 O O   . LEU A 1 314 ? -27.982 -25.111 44.654  1.0 92.43 ? 314 LEU A O   1 O43570 UNP 314 L 
ATOM 2467 C CG  . LEU A 1 314 ? -27.506 -26.854 41.658  1.0 92.43 ? 314 LEU A CG  1 O43570 UNP 314 L 
ATOM 2468 C CD1 . LEU A 1 314 ? -28.874 -27.136 41.030  1.0 92.43 ? 314 LEU A CD1 1 O43570 UNP 314 L 
ATOM 2469 C CD2 . LEU A 1 314 ? -26.489 -27.806 41.033  1.0 92.43 ? 314 LEU A CD2 1 O43570 UNP 314 L 
ATOM 2470 N N   . GLY A 1 315 ? -26.156 -23.911 44.131  1.0 90.60 ? 315 GLY A N   1 O43570 UNP 315 G 
ATOM 2471 C CA  . GLY A 1 315 ? -25.615 -23.844 45.488  1.0 90.60 ? 315 GLY A CA  1 O43570 UNP 315 G 
ATOM 2472 C C   . GLY A 1 315 ? -26.568 -23.154 46.464  1.0 90.60 ? 315 GLY A C   1 O43570 UNP 315 G 
ATOM 2473 O O   . GLY A 1 315 ? -26.846 -23.693 47.537  1.0 90.60 ? 315 GLY A O   1 O43570 UNP 315 G 
ATOM 2474 N N   . ILE A 1 316 ? -27.145 -22.013 46.075  1.0 92.10 ? 316 ILE A N   1 O43570 UNP 316 I 
ATOM 2475 C CA  . ILE A 1 316 ? -28.147 -21.298 46.881  1.0 92.10 ? 316 ILE A CA  1 O43570 UNP 316 I 
ATOM 2476 C C   . ILE A 1 316 ? -29.394 -22.167 47.086  1.0 92.10 ? 316 ILE A C   1 O43570 UNP 316 I 
ATOM 2477 C CB  . ILE A 1 316 ? -28.486 -19.930 46.241  1.0 92.10 ? 316 ILE A CB  1 O43570 UNP 316 I 
ATOM 2478 O O   . ILE A 1 316 ? -29.869 -22.298 48.216  1.0 92.10 ? 316 ILE A O   1 O43570 UNP 316 I 
ATOM 2479 C CG1 . ILE A 1 316 ? -27.260 -18.989 46.313  1.0 92.10 ? 316 ILE A CG1 1 O43570 UNP 316 I 
ATOM 2480 C CG2 . ILE A 1 316 ? -29.689 -19.268 46.944  1.0 92.10 ? 316 ILE A CG2 1 O43570 UNP 316 I 
ATOM 2481 C CD1 . ILE A 1 316 ? -27.375 -17.756 45.407  1.0 92.10 ? 316 ILE A CD1 1 O43570 UNP 316 I 
ATOM 2482 N N   . CYS A 1 317 ? -29.899 -22.820 46.035  1.0 91.70 ? 317 CYS A N   1 O43570 UNP 317 C 
ATOM 2483 C CA  . CYS A 1 317 ? -31.045 -23.724 46.137  1.0 91.70 ? 317 CYS A CA  1 O43570 UNP 317 C 
ATOM 2484 C C   . CYS A 1 317 ? -30.782 -24.879 47.115  1.0 91.70 ? 317 CYS A C   1 O43570 UNP 317 C 
ATOM 2485 C CB  . CYS A 1 317 ? -31.401 -24.261 44.744  1.0 91.70 ? 317 CYS A CB  1 O43570 UNP 317 C 
ATOM 2486 O O   . CYS A 1 317 ? -31.633 -25.170 47.956  1.0 91.70 ? 317 CYS A O   1 O43570 UNP 317 C 
ATOM 2487 S SG  . CYS A 1 317 ? -32.115 -22.947 43.716  1.0 91.70 ? 317 CYS A SG  1 O43570 UNP 317 C 
ATOM 2488 N N   . ILE A 1 318 ? -29.599 -25.501 47.061  1.0 91.58 ? 318 ILE A N   1 O43570 UNP 318 I 
ATOM 2489 C CA  . ILE A 1 318 ? -29.212 -26.576 47.986  1.0 91.58 ? 318 ILE A CA  1 O43570 UNP 318 I 
ATOM 2490 C C   . ILE A 1 318 ? -29.173 -26.056 49.426  1.0 91.58 ? 318 ILE A C   1 O43570 UNP 318 I 
ATOM 2491 C CB  . ILE A 1 318 ? -27.866 -27.207 47.557  1.0 91.58 ? 318 ILE A CB  1 O43570 UNP 318 I 
ATOM 2492 O O   . ILE A 1 318 ? -29.747 -26.685 50.315  1.0 91.58 ? 318 ILE A O   1 O43570 UNP 318 I 
ATOM 2493 C CG1 . ILE A 1 318 ? -28.045 -27.989 46.235  1.0 91.58 ? 318 ILE A CG1 1 O43570 UNP 318 I 
ATOM 2494 C CG2 . ILE A 1 318 ? -27.321 -28.154 48.647  1.0 91.58 ? 318 ILE A CG2 1 O43570 UNP 318 I 
ATOM 2495 C CD1 . ILE A 1 318 ? -26.722 -28.348 45.546  1.0 91.58 ? 318 ILE A CD1 1 O43570 UNP 318 I 
ATOM 2496 N N   . VAL A 1 319 ? -28.563 -24.891 49.668  1.0 90.86 ? 319 VAL A N   1 O43570 UNP 319 V 
ATOM 2497 C CA  . VAL A 1 319 ? -28.499 -24.287 51.011  1.0 90.86 ? 319 VAL A CA  1 O43570 UNP 319 V 
ATOM 2498 C C   . VAL A 1 319 ? -29.897 -23.996 51.555  1.0 90.86 ? 319 VAL A C   1 O43570 UNP 319 V 
ATOM 2499 C CB  . VAL A 1 319 ? -27.624 -23.017 51.001  1.0 90.86 ? 319 VAL A CB  1 O43570 UNP 319 V 
ATOM 2500 O O   . VAL A 1 319 ? -30.172 -24.290 52.721  1.0 90.86 ? 319 VAL A O   1 O43570 UNP 319 V 
ATOM 2501 C CG1 . VAL A 1 319 ? -27.699 -22.242 52.325  1.0 90.86 ? 319 VAL A CG1 1 O43570 UNP 319 V 
ATOM 2502 C CG2 . VAL A 1 319 ? -26.151 -23.387 50.782  1.0 90.86 ? 319 VAL A CG2 1 O43570 UNP 319 V 
ATOM 2503 N N   . VAL A 1 320 ? -30.810 -23.482 50.727  1.0 92.02 ? 320 VAL A N   1 O43570 UNP 320 V 
ATOM 2504 C CA  . VAL A 1 320 ? -32.206 -23.228 51.115  1.0 92.02 ? 320 VAL A CA  1 O43570 UNP 320 V 
ATOM 2505 C C   . VAL A 1 320 ? -32.932 -24.534 51.447  1.0 92.02 ? 320 VAL A C   1 O43570 UNP 320 V 
ATOM 2506 C CB  . VAL A 1 320 ? -32.938 -22.426 50.021  1.0 92.02 ? 320 VAL A CB  1 O43570 UNP 320 V 
ATOM 2507 O O   . VAL A 1 320 ? -33.559 -24.628 52.503  1.0 92.02 ? 320 VAL A O   1 O43570 UNP 320 V 
ATOM 2508 C CG1 . VAL A 1 320 ? -34.446 -22.316 50.285  1.0 92.02 ? 320 VAL A CG1 1 O43570 UNP 320 V 
ATOM 2509 C CG2 . VAL A 1 320 ? -32.385 -20.997 49.944  1.0 92.02 ? 320 VAL A CG2 1 O43570 UNP 320 V 
ATOM 2510 N N   . VAL A 1 321 ? -32.807 -25.571 50.613  1.0 91.07 ? 321 VAL A N   1 O43570 UNP 321 V 
ATOM 2511 C CA  . VAL A 1 321 ? -33.438 -26.882 50.850  1.0 91.07 ? 321 VAL A CA  1 O43570 UNP 321 V 
ATOM 2512 C C   . VAL A 1 321 ? -32.911 -27.531 52.131  1.0 91.07 ? 321 VAL A C   1 O43570 UNP 321 V 
ATOM 2513 C CB  . VAL A 1 321 ? -33.243 -27.807 49.632  1.0 91.07 ? 321 VAL A CB  1 O43570 UNP 321 V 
ATOM 2514 O O   . VAL A 1 321 ? -33.703 -27.993 52.956  1.0 91.07 ? 321 VAL A O   1 O43570 UNP 321 V 
ATOM 2515 C CG1 . VAL A 1 321 ? -33.678 -29.253 49.911  1.0 91.07 ? 321 VAL A CG1 1 O43570 UNP 321 V 
ATOM 2516 C CG2 . VAL A 1 321 ? -34.082 -27.311 48.447  1.0 91.07 ? 321 VAL A CG2 1 O43570 UNP 321 V 
ATOM 2517 N N   . VAL A 1 322 ? -31.593 -27.518 52.349  1.0 90.73 ? 322 VAL A N   1 O43570 UNP 322 V 
ATOM 2518 C CA  . VAL A 1 322 ? -30.966 -28.043 53.572  1.0 90.73 ? 322 VAL A CA  1 O43570 UNP 322 V 
ATOM 2519 C C   . VAL A 1 322 ? -31.420 -27.247 54.794  1.0 90.73 ? 322 VAL A C   1 O43570 UNP 322 V 
ATOM 2520 C CB  . VAL A 1 322 ? -29.429 -28.042 53.443  1.0 90.73 ? 322 VAL A CB  1 O43570 UNP 322 V 
ATOM 2521 O O   . VAL A 1 322 ? -31.752 -27.838 55.822  1.0 90.73 ? 322 VAL A O   1 O43570 UNP 322 V 
ATOM 2522 C CG1 . VAL A 1 322 ? -28.728 -28.386 54.766  1.0 90.73 ? 322 VAL A CG1 1 O43570 UNP 322 V 
ATOM 2523 C CG2 . VAL A 1 322 ? -28.977 -29.083 52.410  1.0 90.73 ? 322 VAL A CG2 1 O43570 UNP 322 V 
ATOM 2524 N N   . SER A 1 323 ? -31.515 -25.921 54.683  1.0 88.93 ? 323 SER A N   1 O43570 UNP 323 S 
ATOM 2525 C CA  . SER A 1 323 ? -32.002 -25.061 55.766  1.0 88.93 ? 323 SER A CA  1 O43570 UNP 323 S 
ATOM 2526 C C   . SER A 1 323 ? -33.453 -25.384 56.124  1.0 88.93 ? 323 SER A C   1 O43570 UNP 323 S 
ATOM 2527 C CB  . SER A 1 323 ? -31.854 -23.583 55.398  1.0 88.93 ? 323 SER A CB  1 O43570 UNP 323 S 
ATOM 2528 O O   . SER A 1 323 ? -33.759 -25.602 57.297  1.0 88.93 ? 323 SER A O   1 O43570 UNP 323 S 
ATOM 2529 O OG  . SER A 1 323 ? -30.492 -23.278 55.205  1.0 88.93 ? 323 SER A OG  1 O43570 UNP 323 S 
ATOM 2530 N N   . ILE A 1 324 ? -34.339 -25.515 55.129  1.0 89.33 ? 324 ILE A N   1 O43570 UNP 324 I 
ATOM 2531 C CA  . ILE A 1 324 ? -35.740 -25.923 55.327  1.0 89.33 ? 324 ILE A CA  1 O43570 UNP 324 I 
ATOM 2532 C C   . ILE A 1 324 ? -35.813 -27.311 55.977  1.0 89.33 ? 324 ILE A C   1 O43570 UNP 324 I 
ATOM 2533 C CB  . ILE A 1 324 ? -36.513 -25.876 53.985  1.0 89.33 ? 324 ILE A CB  1 O43570 UNP 324 I 
ATOM 2534 O O   . ILE A 1 324 ? -36.589 -27.513 56.915  1.0 89.33 ? 324 ILE A O   1 O43570 UNP 324 I 
ATOM 2535 C CG1 . ILE A 1 324 ? -36.670 -24.414 53.504  1.0 89.33 ? 324 ILE A CG1 1 O43570 UNP 324 I 
ATOM 2536 C CG2 . ILE A 1 324 ? -37.908 -26.526 54.119  1.0 89.33 ? 324 ILE A CG2 1 O43570 UNP 324 I 
ATOM 2537 C CD1 . ILE A 1 324 ? -37.136 -24.291 52.046  1.0 89.33 ? 324 ILE A CD1 1 O43570 UNP 324 I 
ATOM 2538 N N   . TRP A 1 325 ? -34.992 -28.264 55.530  1.0 87.32 ? 325 TRP A N   1 O43570 UNP 325 W 
ATOM 2539 C CA  . TRP A 1 325 ? -34.941 -29.612 56.098  1.0 87.32 ? 325 TRP A CA  1 O43570 UNP 325 W 
ATOM 2540 C C   . TRP A 1 325 ? -34.486 -29.609 57.567  1.0 87.32 ? 325 TRP A C   1 O43570 UNP 325 W 
ATOM 2541 C CB  . TRP A 1 325 ? -34.043 -30.493 55.226  1.0 87.32 ? 325 TRP A CB  1 O43570 UNP 325 W 
ATOM 2542 O O   . TRP A 1 325 ? -35.123 -30.242 58.414  1.0 87.32 ? 325 TRP A O   1 O43570 UNP 325 W 
ATOM 2543 C CG  . TRP A 1 325 ? -33.985 -31.922 55.662  1.0 87.32 ? 325 TRP A CG  1 O43570 UNP 325 W 
ATOM 2544 C CD1 . TRP A 1 325 ? -34.883 -32.879 55.337  1.0 87.32 ? 325 TRP A CD1 1 O43570 UNP 325 W 
ATOM 2545 C CD2 . TRP A 1 325 ? -32.978 -32.581 56.489  1.0 87.32 ? 325 TRP A CD2 1 O43570 UNP 325 W 
ATOM 2546 C CE2 . TRP A 1 325 ? -33.341 -33.954 56.627  1.0 87.32 ? 325 TRP A CE2 1 O43570 UNP 325 W 
ATOM 2547 C CE3 . TRP A 1 325 ? -31.778 -32.167 57.107  1.0 87.32 ? 325 TRP A CE3 1 O43570 UNP 325 W 
ATOM 2548 N NE1 . TRP A 1 325 ? -34.511 -34.079 55.909  1.0 87.32 ? 325 TRP A NE1 1 O43570 UNP 325 W 
ATOM 2549 C CH2 . TRP A 1 325 ? -31.347 -34.435 57.910  1.0 87.32 ? 325 TRP A CH2 1 O43570 UNP 325 W 
ATOM 2550 C CZ2 . TRP A 1 325 ? -32.551 -34.872 57.333  1.0 87.32 ? 325 TRP A CZ2 1 O43570 UNP 325 W 
ATOM 2551 C CZ3 . TRP A 1 325 ? -30.967 -33.084 57.807  1.0 87.32 ? 325 TRP A CZ3 1 O43570 UNP 325 W 
ATOM 2552 N N   . LEU A 1 326 ? -33.450 -28.836 57.908  1.0 87.13 ? 326 LEU A N   1 O43570 UNP 326 L 
ATOM 2553 C CA  . LEU A 1 326 ? -32.975 -28.672 59.286  1.0 87.13 ? 326 LEU A CA  1 O43570 UNP 326 L 
ATOM 2554 C C   . LEU A 1 326 ? -34.021 -27.993 60.184  1.0 87.13 ? 326 LEU A C   1 O43570 UNP 326 L 
ATOM 2555 C CB  . LEU A 1 326 ? -31.661 -27.868 59.289  1.0 87.13 ? 326 LEU A CB  1 O43570 UNP 326 L 
ATOM 2556 O O   . LEU A 1 326 ? -34.217 -28.425 61.325  1.0 87.13 ? 326 LEU A O   1 O43570 UNP 326 L 
ATOM 2557 C CG  . LEU A 1 326 ? -30.430 -28.624 58.752  1.0 87.13 ? 326 LEU A CG  1 O43570 UNP 326 L 
ATOM 2558 C CD1 . LEU A 1 326 ? -29.244 -27.663 58.681  1.0 87.13 ? 326 LEU A CD1 1 O43570 UNP 326 L 
ATOM 2559 C CD2 . LEU A 1 326 ? -30.040 -29.802 59.650  1.0 87.13 ? 326 LEU A CD2 1 O43570 UNP 326 L 
ATOM 2560 N N   . PHE A 1 327 ? -34.726 -26.975 59.679  1.0 83.11 ? 327 PHE A N   1 O43570 UNP 327 F 
ATOM 2561 C CA  . PHE A 1 327 ? -35.826 -26.325 60.397  1.0 83.11 ? 327 PHE A CA  1 O43570 UNP 327 F 
ATOM 2562 C C   . PHE A 1 327 ? -36.990 -27.290 60.652  1.0 83.11 ? 327 PHE A C   1 O43570 UNP 327 F 
ATOM 2563 C CB  . PHE A 1 327 ? -36.295 -25.068 59.646  1.0 83.11 ? 327 PHE A CB  1 O43570 UNP 327 F 
ATOM 2564 O O   . PHE A 1 327 ? -37.479 -27.371 61.781  1.0 83.11 ? 327 PHE A O   1 O43570 UNP 327 F 
ATOM 2565 C CG  . PHE A 1 327 ? -35.652 -23.790 60.152  1.0 83.11 ? 327 PHE A CG  1 O43570 UNP 327 F 
ATOM 2566 C CD1 . PHE A 1 327 ? -36.145 -23.182 61.323  1.0 83.11 ? 327 PHE A CD1 1 O43570 UNP 327 F 
ATOM 2567 C CD2 . PHE A 1 327 ? -34.579 -23.194 59.463  1.0 83.11 ? 327 PHE A CD2 1 O43570 UNP 327 F 
ATOM 2568 C CE1 . PHE A 1 327 ? -35.569 -21.990 61.798  1.0 83.11 ? 327 PHE A CE1 1 O43570 UNP 327 F 
ATOM 2569 C CE2 . PHE A 1 327 ? -33.999 -22.007 59.940  1.0 83.11 ? 327 PHE A CE2 1 O43570 UNP 327 F 
ATOM 2570 C CZ  . PHE A 1 327 ? -34.495 -21.403 61.107  1.0 83.11 ? 327 PHE A CZ  1 O43570 UNP 327 F 
ATOM 2571 N N   . ARG A 1 328 ? -37.385 -28.093 59.653  1.0 82.58 ? 328 ARG A N   1 O43570 UNP 328 R 
ATOM 2572 C CA  . ARG A 1 328 ? -38.413 -29.135 59.816  1.0 82.58 ? 328 ARG A CA  1 O43570 UNP 328 R 
ATOM 2573 C C   . ARG A 1 328 ? -37.990 -30.195 60.834  1.0 82.58 ? 328 ARG A C   1 O43570 UNP 328 R 
ATOM 2574 C CB  . ARG A 1 328 ? -38.760 -29.765 58.456  1.0 82.58 ? 328 ARG A CB  1 O43570 UNP 328 R 
ATOM 2575 O O   . ARG A 1 328 ? -38.779 -30.534 61.712  1.0 82.58 ? 328 ARG A O   1 O43570 UNP 328 R 
ATOM 2576 C CG  . ARG A 1 328 ? -39.640 -28.837 57.603  1.0 82.58 ? 328 ARG A CG  1 O43570 UNP 328 R 
ATOM 2577 C CD  . ARG A 1 328 ? -40.018 -29.514 56.280  1.0 82.58 ? 328 ARG A CD  1 O43570 UNP 328 R 
ATOM 2578 N NE  . ARG A 1 328 ? -40.993 -28.710 55.516  1.0 82.58 ? 328 ARG A NE  1 O43570 UNP 328 R 
ATOM 2579 N NH1 . ARG A 1 328 ? -41.470 -30.264 53.886  1.0 82.58 ? 328 ARG A NH1 1 O43570 UNP 328 R 
ATOM 2580 N NH2 . ARG A 1 328 ? -42.500 -28.290 53.856  1.0 82.58 ? 328 ARG A NH2 1 O43570 UNP 328 R 
ATOM 2581 C CZ  . ARG A 1 328 ? -41.646 -29.091 54.429  1.0 82.58 ? 328 ARG A CZ  1 O43570 UNP 328 R 
ATOM 2582 N N   . ARG A 1 329 ? -36.733 -30.652 60.804  1.0 79.46 ? 329 ARG A N   1 O43570 UNP 329 R 
ATOM 2583 C CA  . ARG A 1 329 ? -36.204 -31.635 61.769  1.0 79.46 ? 329 ARG A CA  1 O43570 UNP 329 R 
ATOM 2584 C C   . ARG A 1 329 ? -36.162 -31.088 63.201  1.0 79.46 ? 329 ARG A C   1 O43570 UNP 329 R 
ATOM 2585 C CB  . ARG A 1 329 ? -34.828 -32.120 61.284  1.0 79.46 ? 329 ARG A CB  1 O43570 UNP 329 R 
ATOM 2586 O O   . ARG A 1 329 ? -36.476 -31.821 64.138  1.0 79.46 ? 329 ARG A O   1 O43570 UNP 329 R 
ATOM 2587 C CG  . ARG A 1 329 ? -34.375 -33.397 62.008  1.0 79.46 ? 329 ARG A CG  1 O43570 UNP 329 R 
ATOM 2588 C CD  . ARG A 1 329 ? -33.030 -33.877 61.448  1.0 79.46 ? 329 ARG A CD  1 O43570 UNP 329 R 
ATOM 2589 N NE  . ARG A 1 329 ? -32.611 -35.160 62.052  1.0 79.46 ? 329 ARG A NE  1 O43570 UNP 329 R 
ATOM 2590 N NH1 . ARG A 1 329 ? -30.469 -35.181 61.218  1.0 79.46 ? 329 ARG A NH1 1 O43570 UNP 329 R 
ATOM 2591 N NH2 . ARG A 1 329 ? -31.178 -36.890 62.463  1.0 79.46 ? 329 ARG A NH2 1 O43570 UNP 329 R 
ATOM 2592 C CZ  . ARG A 1 329 ? -31.426 -35.734 61.910  1.0 79.46 ? 329 ARG A CZ  1 O43570 UNP 329 R 
ATOM 2593 N N   . LYS A 1 330 ? -35.813 -29.807 63.388  1.0 73.56 ? 330 LYS A N   1 O43570 UNP 330 K 
ATOM 2594 C CA  . LYS A 1 330 ? -35.894 -29.134 64.699  1.0 73.56 ? 330 LYS A CA  1 O43570 UNP 330 K 
ATOM 2595 C C   . LYS A 1 330 ? -37.338 -28.968 65.179  1.0 73.56 ? 330 LYS A C   1 O43570 UNP 330 K 
ATOM 2596 C CB  . LYS A 1 330 ? -35.176 -27.771 64.673  1.0 73.56 ? 330 LYS A CB  1 O43570 UNP 330 K 
ATOM 2597 O O   . LYS A 1 330 ? -37.575 -29.127 66.372  1.0 73.56 ? 330 LYS A O   1 O43570 UNP 330 K 
ATOM 2598 C CG  . LYS A 1 330 ? -33.663 -27.886 64.924  1.0 73.56 ? 330 LYS A CG  1 O43570 UNP 330 K 
ATOM 2599 C CD  . LYS A 1 330 ? -33.020 -26.491 65.024  1.0 73.56 ? 330 LYS A CD  1 O43570 UNP 330 K 
ATOM 2600 C CE  . LYS A 1 330 ? -31.526 -26.585 65.374  1.0 73.56 ? 330 LYS A CE  1 O43570 UNP 330 K 
ATOM 2601 N NZ  . LYS A 1 330 ? -30.877 -25.247 65.430  1.0 73.56 ? 330 LYS A NZ  1 O43570 UNP 330 K 
ATOM 2602 N N   . SER A 1 331 ? -38.284 -28.686 64.280  1.0 62.03 ? 331 SER A N   1 O43570 UNP 331 S 
ATOM 2603 C CA  . SER A 1 331 ? -39.711 -28.583 64.620  1.0 62.03 ? 331 SER A CA  1 O43570 UNP 331 S 
ATOM 2604 C C   . SER A 1 331 ? -40.285 -29.929 65.082  1.0 62.03 ? 331 SER A C   1 O43570 UNP 331 S 
ATOM 2605 C CB  . SER A 1 331 ? -40.503 -28.028 63.433  1.0 62.03 ? 331 SER A CB  1 O43570 UNP 331 S 
ATOM 2606 O O   . SER A 1 331 ? -40.918 -29.990 66.132  1.0 62.03 ? 331 SER A O   1 O43570 UNP 331 S 
ATOM 2607 O OG  . SER A 1 331 ? -41.757 -27.581 63.895  1.0 62.03 ? 331 SER A OG  1 O43570 UNP 331 S 
ATOM 2608 N N   . ILE A 1 332 ? -39.949 -31.026 64.391  1.0 62.08 ? 332 ILE A N   1 O43570 UNP 332 I 
ATOM 2609 C CA  . ILE A 1 332 ? -40.356 -32.391 64.774  1.0 62.08 ? 332 ILE A CA  1 O43570 UNP 332 I 
ATOM 2610 C C   . ILE A 1 332 ? -39.777 -32.774 66.148  1.0 62.08 ? 332 ILE A C   1 O43570 UNP 332 I 
ATOM 2611 C CB  . ILE A 1 332 ? -39.981 -33.393 63.655  1.0 62.08 ? 332 ILE A CB  1 O43570 UNP 332 I 
ATOM 2612 O O   . ILE A 1 332 ? -40.511 -33.229 67.017  1.0 62.08 ? 332 ILE A O   1 O43570 UNP 332 I 
ATOM 2613 C CG1 . ILE A 1 332 ? -40.805 -33.099 62.376  1.0 62.08 ? 332 ILE A CG1 1 O43570 UNP 332 I 
ATOM 2614 C CG2 . ILE A 1 332 ? -40.224 -34.848 64.097  1.0 62.08 ? 332 ILE A CG2 1 O43570 UNP 332 I 
ATOM 2615 C CD1 . ILE A 1 332 ? -40.268 -33.788 61.114  1.0 62.08 ? 332 ILE A CD1 1 O43570 UNP 332 I 
ATOM 2616 N N   . LYS A 1 333 ? -38.495 -32.472 66.415  1.0 57.59 ? 333 LYS A N   1 O43570 UNP 333 K 
ATOM 2617 C CA  . LYS A 1 333 ? -37.888 -32.703 67.743  1.0 57.59 ? 333 LYS A CA  1 O43570 UNP 333 K 
ATOM 2618 C C   . LYS A 1 333 ? -38.464 -31.824 68.865  1.0 57.59 ? 333 LYS A C   1 O43570 UNP 333 K 
ATOM 2619 C CB  . LYS A 1 333 ? -36.362 -32.543 67.676  1.0 57.59 ? 333 LYS A CB  1 O43570 UNP 333 K 
ATOM 2620 O O   . LYS A 1 333 ? -38.358 -32.196 70.029  1.0 57.59 ? 333 LYS A O   1 O43570 UNP 333 K 
ATOM 2621 C CG  . LYS A 1 333 ? -35.678 -33.752 67.021  1.0 57.59 ? 333 LYS A CG  1 O43570 UNP 333 K 
ATOM 2622 C CD  . LYS A 1 333 ? -34.155 -33.652 67.185  1.0 57.59 ? 333 LYS A CD  1 O43570 UNP 333 K 
ATOM 2623 C CE  . LYS A 1 333 ? -33.479 -34.923 66.660  1.0 57.59 ? 333 LYS A CE  1 O43570 UNP 333 K 
ATOM 2624 N NZ  . LYS A 1 333 ? -32.042 -34.971 67.035  1.0 57.59 ? 333 LYS A NZ  1 O43570 UNP 333 K 
ATOM 2625 N N   . LYS A 1 334 ? -39.053 -30.664 68.550  1.0 53.79 ? 334 LYS A N   1 O43570 UNP 334 K 
ATOM 2626 C CA  . LYS A 1 334 ? -39.771 -29.821 69.528  1.0 53.79 ? 334 LYS A CA  1 O43570 UNP 334 K 
ATOM 2627 C C   . LYS A 1 334 ? -41.228 -30.258 69.736  1.0 53.79 ? 334 LYS A C   1 O43570 UNP 334 K 
ATOM 2628 C CB  . LYS A 1 334 ? -39.670 -28.330 69.141  1.0 53.79 ? 334 LYS A CB  1 O43570 UNP 334 K 
ATOM 2629 O O   . LYS A 1 334 ? -41.812 -29.866 70.744  1.0 53.79 ? 334 LYS A O   1 O43570 UNP 334 K 
ATOM 2630 C CG  . LYS A 1 334 ? -38.654 -27.579 70.018  1.0 53.79 ? 334 LYS A CG  1 O43570 UNP 334 K 
ATOM 2631 C CD  . LYS A 1 334 ? -38.600 -26.084 69.662  1.0 53.79 ? 334 LYS A CD  1 O43570 UNP 334 K 
ATOM 2632 C CE  . LYS A 1 334 ? -37.692 -25.329 70.643  1.0 53.79 ? 334 LYS A CE  1 O43570 UNP 334 K 
ATOM 2633 N NZ  . LYS A 1 334 ? -37.651 -23.869 70.359  1.0 53.79 ? 334 LYS A NZ  1 O43570 UNP 334 K 
ATOM 2634 N N   . GLY A 1 335 ? -41.790 -31.047 68.818  1.0 53.03 ? 335 GLY A N   1 O43570 UNP 335 G 
ATOM 2635 C CA  . GLY A 1 335 ? -43.135 -31.622 68.908  1.0 53.03 ? 335 GLY A CA  1 O43570 UNP 335 G 
ATOM 2636 C C   . GLY A 1 335 ? -43.219 -32.853 69.814  1.0 53.03 ? 335 GLY A C   1 O43570 UNP 335 G 
ATOM 2637 O O   . GLY A 1 335 ? -44.185 -32.971 70.556  1.0 53.03 ? 335 GLY A O   1 O43570 UNP 335 G 
ATOM 2638 N N   . ASP A 1 336 ? -42.180 -33.695 69.840  1.0 53.67 ? 336 ASP A N   1 O43570 UNP 336 D 
ATOM 2639 C CA  . ASP A 1 336 ? -42.159 -34.929 70.654  1.0 53.67 ? 336 ASP A CA  1 O43570 UNP 336 D 
ATOM 2640 C C   . ASP A 1 336 ? -41.844 -34.714 72.146  1.0 53.67 ? 336 ASP A C   1 O43570 UNP 336 D 
ATOM 2641 C CB  . ASP A 1 336 ? -41.171 -35.940 70.035  1.0 53.67 ? 336 ASP A CB  1 O43570 UNP 336 D 
ATOM 2642 O O   . ASP A 1 336 ? -42.015 -35.620 72.954  1.0 53.67 ? 336 ASP A O   1 O43570 UNP 336 D 
ATOM 2643 C CG  . ASP A 1 336 ? -41.820 -36.998 69.134  1.0 53.67 ? 336 ASP A CG  1 O43570 UNP 336 D 
ATOM 2644 O OD1 . ASP A 1 336 ? -43.062 -37.131 69.152  1.0 53.67 ? 336 ASP A OD1 1 O43570 UNP 336 D 
ATOM 2645 O OD2 . ASP A 1 336 ? -41.038 -37.649 68.405  1.0 53.67 ? 336 ASP A OD2 1 O43570 UNP 336 D 
ATOM 2646 N N   . ASN A 1 337 ? -41.428 -33.509 72.550  1.0 51.04 ? 337 ASN A N   1 O43570 UNP 337 N 
ATOM 2647 C CA  . ASN A 1 337 ? -41.100 -33.189 73.949  1.0 51.04 ? 337 ASN A CA  1 O43570 UNP 337 N 
ATOM 2648 C C   . ASN A 1 337 ? -42.204 -32.405 74.685  1.0 51.04 ? 337 ASN A C   1 O43570 UNP 337 N 
ATOM 2649 C CB  . ASN A 1 337 ? -39.684 -32.569 74.026  1.0 51.04 ? 337 ASN A CB  1 O43570 UNP 337 N 
ATOM 2650 O O   . ASN A 1 337 ? -41.945 -31.747 75.695  1.0 51.04 ? 337 ASN A O   1 O43570 UNP 337 N 
ATOM 2651 C CG  . ASN A 1 337 ? -38.628 -33.532 74.556  1.0 51.04 ? 337 ASN A CG  1 O43570 UNP 337 N 
ATOM 2652 N ND2 . ASN A 1 337 ? -37.435 -33.050 74.809  1.0 51.04 ? 337 ASN A ND2 1 O43570 UNP 337 N 
ATOM 2653 O OD1 . ASN A 1 337 ? -38.824 -34.711 74.767  1.0 51.04 ? 337 ASN A OD1 1 O43570 UNP 337 N 
ATOM 2654 N N   . LYS A 1 338 ? -43.450 -32.469 74.199  1.0 48.65 ? 338 LYS A N   1 O43570 UNP 338 K 
ATOM 2655 C CA  . LYS A 1 338 ? -44.628 -31.910 74.875  1.0 48.65 ? 338 LYS A CA  1 O43570 UNP 338 K 
ATOM 2656 C C   . LYS A 1 338 ? -45.655 -33.005 75.168  1.0 48.65 ? 338 LYS A C   1 O43570 UNP 338 K 
ATOM 2657 C CB  . LYS A 1 338 ? -45.254 -30.784 74.032  1.0 48.65 ? 338 LYS A CB  1 O43570 UNP 338 K 
ATOM 2658 O O   . LYS A 1 338 ? -46.463 -33.330 74.310  1.0 48.65 ? 338 LYS A O   1 O43570 UNP 338 K 
ATOM 2659 C CG  . LYS A 1 338 ? -44.491 -29.455 74.120  1.0 48.65 ? 338 LYS A CG  1 O43570 UNP 338 K 
ATOM 2660 C CD  . LYS A 1 338 ? -45.289 -28.363 73.395  1.0 48.65 ? 338 LYS A CD  1 O43570 UNP 338 K 
ATOM 2661 C CE  . LYS A 1 338 ? -44.615 -26.996 73.538  1.0 48.65 ? 338 LYS A CE  1 O43570 UNP 338 K 
ATOM 2662 N NZ  . LYS A 1 338 ? -45.439 -25.934 72.906  1.0 48.65 ? 338 LYS A NZ  1 O43570 UNP 338 K 
ATOM 2663 N N   . GLY A 1 339 ? -45.694 -33.467 76.419  1.0 43.13 ? 339 GLY A N   1 O43570 UNP 339 G 
ATOM 2664 C CA  . GLY A 1 339 ? -46.945 -33.940 77.018  1.0 43.13 ? 339 GLY A CA  1 O43570 UNP 339 G 
ATOM 2665 C C   . GLY A 1 339 ? -46.946 -35.352 77.595  1.0 43.13 ? 339 GLY A C   1 O43570 UNP 339 G 
ATOM 2666 O O   . GLY A 1 339 ? -47.607 -36.231 77.061  1.0 43.13 ? 339 GLY A O   1 O43570 UNP 339 G 
ATOM 2667 N N   . VAL A 1 340 ? -46.351 -35.524 78.776  1.0 47.48 ? 340 VAL A N   1 O43570 UNP 340 V 
ATOM 2668 C CA  . VAL A 1 340 ? -46.914 -36.426 79.793  1.0 47.48 ? 340 VAL A CA  1 O43570 UNP 340 V 
ATOM 2669 C C   . VAL A 1 340 ? -47.071 -35.600 81.069  1.0 47.48 ? 340 VAL A C   1 O43570 UNP 340 V 
ATOM 2670 C CB  . VAL A 1 340 ? -46.090 -37.717 79.998  1.0 47.48 ? 340 VAL A CB  1 O43570 UNP 340 V 
ATOM 2671 O O   . VAL A 1 340 ? -46.158 -35.498 81.880  1.0 47.48 ? 340 VAL A O   1 O43570 UNP 340 V 
ATOM 2672 C CG1 . VAL A 1 340 ? -46.804 -38.654 80.985  1.0 47.48 ? 340 VAL A CG1 1 O43570 UNP 340 V 
ATOM 2673 C CG2 . VAL A 1 340 ? -45.904 -38.493 78.687  1.0 47.48 ? 340 VAL A CG2 1 O43570 UNP 340 V 
ATOM 2674 N N   . ILE A 1 341 ? -48.211 -34.914 81.202  1.0 55.76 ? 341 ILE A N   1 O43570 UNP 341 I 
ATOM 2675 C CA  . ILE A 1 341 ? -48.602 -34.243 82.449  1.0 55.76 ? 341 ILE A CA  1 O43570 UNP 341 I 
ATOM 2676 C C   . ILE A 1 341 ? -49.462 -35.236 83.230  1.0 55.76 ? 341 ILE A C   1 O43570 UNP 341 I 
ATOM 2677 C CB  . ILE A 1 341 ? -49.304 -32.886 82.195  1.0 55.76 ? 341 ILE A CB  1 O43570 UNP 341 I 
ATOM 2678 O O   . ILE A 1 341 ? -50.616 -35.482 82.886  1.0 55.76 ? 341 ILE A O   1 O43570 UNP 341 I 
ATOM 2679 C CG1 . ILE A 1 341 ? -48.318 -31.903 81.517  1.0 55.76 ? 341 ILE A CG1 1 O43570 UNP 341 I 
ATOM 2680 C CG2 . ILE A 1 341 ? -49.832 -32.291 83.518  1.0 55.76 ? 341 ILE A CG2 1 O43570 UNP 341 I 
ATOM 2681 C CD1 . ILE A 1 341 ? -48.930 -30.549 81.130  1.0 55.76 ? 341 ILE A CD1 1 O43570 UNP 341 I 
ATOM 2682 N N   . TYR A 1 342 ? -48.873 -35.815 84.273  1.0 48.47 ? 342 TYR A N   1 O43570 UNP 342 Y 
ATOM 2683 C CA  . TYR A 1 342 ? -49.556 -36.641 85.267  1.0 48.47 ? 342 TYR A CA  1 O43570 UNP 342 Y 
ATOM 2684 C C   . TYR A 1 342 ? -50.440 -35.732 86.140  1.0 48.47 ? 342 TYR A C   1 O43570 UNP 342 Y 
ATOM 2685 C CB  . TYR A 1 342 ? -48.486 -37.385 86.098  1.0 48.47 ? 342 TYR A CB  1 O43570 UNP 342 Y 
ATOM 2686 O O   . TYR A 1 342 ? -49.929 -34.816 86.785  1.0 48.47 ? 342 TYR A O   1 O43570 UNP 342 Y 
ATOM 2687 C CG  . TYR A 1 342 ? -48.674 -38.885 86.203  1.0 48.47 ? 342 TYR A CG  1 O43570 UNP 342 Y 
ATOM 2688 C CD1 . TYR A 1 342 ? -49.290 -39.442 87.341  1.0 48.47 ? 342 TYR A CD1 1 O43570 UNP 342 Y 
ATOM 2689 C CD2 . TYR A 1 342 ? -48.187 -39.727 85.183  1.0 48.47 ? 342 TYR A CD2 1 O43570 UNP 342 Y 
ATOM 2690 C CE1 . TYR A 1 342 ? -49.416 -40.840 87.463  1.0 48.47 ? 342 TYR A CE1 1 O43570 UNP 342 Y 
ATOM 2691 C CE2 . TYR A 1 342 ? -48.314 -41.124 85.302  1.0 48.47 ? 342 TYR A CE2 1 O43570 UNP 342 Y 
ATOM 2692 O OH  . TYR A 1 342 ? -49.036 -43.033 86.553  1.0 48.47 ? 342 TYR A OH  1 O43570 UNP 342 Y 
ATOM 2693 C CZ  . TYR A 1 342 ? -48.925 -41.684 86.443  1.0 48.47 ? 342 TYR A CZ  1 O43570 UNP 342 Y 
ATOM 2694 N N   . LYS A 1 343 ? -51.761 -35.952 86.168  1.0 56.87 ? 343 LYS A N   1 O43570 UNP 343 K 
ATOM 2695 C CA  . LYS A 1 343 ? -52.662 -35.309 87.144  1.0 56.87 ? 343 LYS A CA  1 O43570 UNP 343 K 
ATOM 2696 C C   . LYS A 1 343 ? -52.811 -36.221 88.372  1.0 56.87 ? 343 LYS A C   1 O43570 UNP 343 K 
ATOM 2697 C CB  . LYS A 1 343 ? -54.040 -34.999 86.532  1.0 56.87 ? 343 LYS A CB  1 O43570 UNP 343 K 
ATOM 2698 O O   . LYS A 1 343 ? -53.268 -37.349 88.194  1.0 56.87 ? 343 LYS A O   1 O43570 UNP 343 K 
ATOM 2699 C CG  . LYS A 1 343 ? -54.067 -33.673 85.755  1.0 56.87 ? 343 LYS A CG  1 O43570 UNP 343 K 
ATOM 2700 C CD  . LYS A 1 343 ? -55.503 -33.341 85.321  1.0 56.87 ? 343 LYS A CD  1 O43570 UNP 343 K 
ATOM 2701 C CE  . LYS A 1 343 ? -55.574 -31.962 84.654  1.0 56.87 ? 343 LYS A CE  1 O43570 UNP 343 K 
ATOM 2702 N NZ  . LYS A 1 343 ? -56.968 -31.612 84.279  1.0 56.87 ? 343 LYS A NZ  1 O43570 UNP 343 K 
ATOM 2703 N N   . PRO A 1 344 ? -52.473 -35.774 89.596  1.0 51.87 ? 344 PRO A N   1 O43570 UNP 344 P 
ATOM 2704 C CA  . PRO A 1 344 ? -52.758 -36.528 90.810  1.0 51.87 ? 344 PRO A CA  1 O43570 UNP 344 P 
ATOM 2705 C C   . PRO A 1 344 ? -54.222 -36.334 91.229  1.0 51.87 ? 344 PRO A C   1 O43570 UNP 344 P 
ATOM 2706 C CB  . PRO A 1 344 ? -51.779 -36.017 91.872  1.0 51.87 ? 344 PRO A CB  1 O43570 UNP 344 P 
ATOM 2707 O O   . PRO A 1 344 ? -54.761 -35.232 91.132  1.0 51.87 ? 344 PRO A O   1 O43570 UNP 344 P 
ATOM 2708 C CG  . PRO A 1 344 ? -51.173 -34.731 91.299  1.0 51.87 ? 344 PRO A CG  1 O43570 UNP 344 P 
ATOM 2709 C CD  . PRO A 1 344 ? -51.843 -34.511 89.944  1.0 51.87 ? 344 PRO A CD  1 O43570 UNP 344 P 
ATOM 2710 N N   . ALA A 1 345 ? -54.860 -37.403 91.707  1.0 44.75 ? 345 ALA A N   1 O43570 UNP 345 A 
ATOM 2711 C CA  . ALA A 1 345 ? -56.171 -37.344 92.341  1.0 44.75 ? 345 ALA A CA  1 O43570 UNP 345 A 
ATOM 2712 C C   . ALA A 1 345 ? -56.007 -36.992 93.827  1.0 44.75 ? 345 ALA A C   1 O43570 UNP 345 A 
ATOM 2713 C CB  . ALA A 1 345 ? -56.877 -38.694 92.139  1.0 44.75 ? 345 ALA A CB  1 O43570 UNP 345 A 
ATOM 2714 O O   . ALA A 1 345 ? -55.452 -37.780 94.589  1.0 44.75 ? 345 ALA A O   1 O43570 UNP 345 A 
ATOM 2715 N N   . THR A 1 346 ? -56.512 -35.833 94.246  1.0 56.84 ? 346 THR A N   1 O43570 UNP 346 T 
ATOM 2716 C CA  . THR A 1 346 ? -56.635 -35.451 95.659  1.0 56.84 ? 346 THR A CA  1 O43570 UNP 346 T 
ATOM 2717 C C   . THR A 1 346 ? -58.107 -35.259 96.009  1.0 56.84 ? 346 THR A C   1 O43570 UNP 346 T 
ATOM 2718 C CB  . THR A 1 346 ? -55.800 -34.207 96.031  1.0 56.84 ? 346 THR A CB  1 O43570 UNP 346 T 
ATOM 2719 O O   . THR A 1 346 ? -58.779 -34.374 95.488  1.0 56.84 ? 346 THR A O   1 O43570 UNP 346 T 
ATOM 2720 C CG2 . THR A 1 346 ? -54.507 -34.613 96.737  1.0 56.84 ? 346 THR A CG2 1 O43570 UNP 346 T 
ATOM 2721 O OG1 . THR A 1 346 ? -55.421 -33.450 94.901  1.0 56.84 ? 346 THR A OG1 1 O43570 UNP 346 T 
ATOM 2722 N N   . LYS A 1 347 ? -58.600 -36.128 96.900  1.0 47.55 ? 347 LYS A N   1 O43570 UNP 347 K 
ATOM 2723 C CA  . LYS A 1 347 ? -59.822 -35.929 97.685  1.0 47.55 ? 347 LYS A CA  1 O43570 UNP 347 K 
ATOM 2724 C C   . LYS A 1 347 ? -59.517 -34.921 98.794  1.0 47.55 ? 347 LYS A C   1 O43570 UNP 347 K 
ATOM 2725 C CB  . LYS A 1 347 ? -60.255 -37.253 98.346  1.0 47.55 ? 347 LYS A CB  1 O43570 UNP 347 K 
ATOM 2726 O O   . LYS A 1 347 ? -58.532 -35.101 99.503  1.0 47.55 ? 347 LYS A O   1 O43570 UNP 347 K 
ATOM 2727 C CG  . LYS A 1 347 ? -60.947 -38.257 97.413  1.0 47.55 ? 347 LYS A CG  1 O43570 UNP 347 K 
ATOM 2728 C CD  . LYS A 1 347 ? -61.345 -39.505 98.220  1.0 47.55 ? 347 LYS A CD  1 O43570 UNP 347 K 
ATOM 2729 C CE  . LYS A 1 347 ? -62.198 -40.470 97.389  1.0 47.55 ? 347 LYS A CE  1 O43570 UNP 347 K 
ATOM 2730 N NZ  . LYS A 1 347 ? -62.649 -41.627 98.205  1.0 47.55 ? 347 LYS A NZ  1 O43570 UNP 347 K 
ATOM 2731 N N   . MET A 1 348 ? -60.374 -33.924 98.971  1.0 53.30 ? 348 MET A N   1 O43570 UNP 348 M 
ATOM 2732 C CA  . MET A 1 348 ? -60.462 -33.145 100.206 1.0 53.30 ? 348 MET A CA  1 O43570 UNP 348 M 
ATOM 2733 C C   . MET A 1 348 ? -61.899 -32.636 100.355 1.0 53.30 ? 348 MET A C   1 O43570 UNP 348 M 
ATOM 2734 C CB  . MET A 1 348 ? -59.421 -32.003 100.229 1.0 53.30 ? 348 MET A CB  1 O43570 UNP 348 M 
ATOM 2735 O O   . MET A 1 348 ? -62.300 -31.688 99.688  1.0 53.30 ? 348 MET A O   1 O43570 UNP 348 M 
ATOM 2736 C CG  . MET A 1 348 ? -58.353 -32.251 101.302 1.0 53.30 ? 348 MET A CG  1 O43570 UNP 348 M 
ATOM 2737 S SD  . MET A 1 348 ? -57.080 -30.963 101.400 1.0 53.30 ? 348 MET A SD  1 O43570 UNP 348 M 
ATOM 2738 C CE  . MET A 1 348 ? -56.421 -31.322 103.051 1.0 53.30 ? 348 MET A CE  1 O43570 UNP 348 M 
ATOM 2739 N N   . GLU A 1 349 ? -62.667 -33.313 101.207 1.0 54.85 ? 349 GLU A N   1 O43570 UNP 349 E 
ATOM 2740 C CA  . GLU A 1 349 ? -63.770 -32.710 101.954 1.0 54.85 ? 349 GLU A CA  1 O43570 UNP 349 E 
ATOM 2741 C C   . GLU A 1 349 ? -63.198 -32.313 103.316 1.0 54.85 ? 349 GLU A C   1 O43570 UNP 349 E 
ATOM 2742 C CB  . GLU A 1 349 ? -64.962 -33.676 102.099 1.0 54.85 ? 349 GLU A CB  1 O43570 UNP 349 E 
ATOM 2743 O O   . GLU A 1 349 ? -62.567 -33.119 104.000 1.0 54.85 ? 349 GLU A O   1 O43570 UNP 349 E 
ATOM 2744 C CG  . GLU A 1 349 ? -66.037 -33.399 101.037 1.0 54.85 ? 349 GLU A CG  1 O43570 UNP 349 E 
ATOM 2745 C CD  . GLU A 1 349 ? -67.213 -34.390 101.083 1.0 54.85 ? 349 GLU A CD  1 O43570 UNP 349 E 
ATOM 2746 O OE1 . GLU A 1 349 ? -68.318 -33.987 100.655 1.0 54.85 ? 349 GLU A OE1 1 O43570 UNP 349 E 
ATOM 2747 O OE2 . GLU A 1 349 ? -66.984 -35.563 101.458 1.0 54.85 ? 349 GLU A OE2 1 O43570 UNP 349 E 
ATOM 2748 N N   . THR A 1 350 ? -63.350 -31.036 103.642 1.0 53.23 ? 350 THR A N   1 O43570 UNP 350 T 
ATOM 2749 C CA  . THR A 1 350 ? -62.937 -30.382 104.882 1.0 53.23 ? 350 THR A CA  1 O43570 UNP 350 T 
ATOM 2750 C C   . THR A 1 350 ? -63.980 -30.597 105.974 1.0 53.23 ? 350 THR A C   1 O43570 UNP 350 T 
ATOM 2751 C CB  . THR A 1 350 ? -62.745 -28.865 104.648 1.0 53.23 ? 350 THR A CB  1 O43570 UNP 350 T 
ATOM 2752 O O   . THR A 1 350 ? -65.158 -30.307 105.768 1.0 53.23 ? 350 THR A O   1 O43570 UNP 350 T 
ATOM 2753 C CG2 . THR A 1 350 ? -61.270 -28.493 104.532 1.0 53.23 ? 350 THR A CG2 1 O43570 UNP 350 T 
ATOM 2754 O OG1 . THR A 1 350 ? -63.363 -28.414 103.453 1.0 53.23 ? 350 THR A OG1 1 O43570 UNP 350 T 
ATOM 2755 N N   . GLU A 1 351 ? -63.529 -31.047 107.145 1.0 49.88 ? 351 GLU A N   1 O43570 UNP 351 E 
ATOM 2756 C CA  . GLU A 1 351 ? -64.284 -31.001 108.398 1.0 49.88 ? 351 GLU A CA  1 O43570 UNP 351 E 
ATOM 2757 C C   . GLU A 1 351 ? -64.492 -29.558 108.875 1.0 49.88 ? 351 GLU A C   1 O43570 UNP 351 E 
ATOM 2758 C CB  . GLU A 1 351 ? -63.560 -31.801 109.496 1.0 49.88 ? 351 GLU A CB  1 O43570 UNP 351 E 
ATOM 2759 O O   . GLU A 1 351 ? -63.640 -28.682 108.704 1.0 49.88 ? 351 GLU A O   1 O43570 UNP 351 E 
ATOM 2760 C CG  . GLU A 1 351 ? -63.795 -33.312 109.365 1.0 49.88 ? 351 GLU A CG  1 O43570 UNP 351 E 
ATOM 2761 C CD  . GLU A 1 351 ? -63.011 -34.137 110.400 1.0 49.88 ? 351 GLU A CD  1 O43570 UNP 351 E 
ATOM 2762 O OE1 . GLU A 1 351 ? -63.518 -35.219 110.775 1.0 49.88 ? 351 GLU A OE1 1 O43570 UNP 351 E 
ATOM 2763 O OE2 . GLU A 1 351 ? -61.886 -33.720 110.756 1.0 49.88 ? 351 GLU A OE2 1 O43570 UNP 351 E 
ATOM 2764 N N   . ALA A 1 352 ? -65.643 -29.347 109.509 1.0 46.87 ? 352 ALA A N   1 O43570 UNP 352 A 
ATOM 2765 C CA  . ALA A 1 352 ? -65.989 -28.168 110.275 1.0 46.87 ? 352 ALA A CA  1 O43570 UNP 352 A 
ATOM 2766 C C   . ALA A 1 352 ? -65.943 -28.494 111.779 1.0 46.87 ? 352 ALA A C   1 O43570 UNP 352 A 
ATOM 2767 C CB  . ALA A 1 352 ? -67.381 -27.696 109.827 1.0 46.87 ? 352 ALA A CB  1 O43570 UNP 352 A 
ATOM 2768 O O   . ALA A 1 352 ? -66.398 -29.558 112.190 1.0 46.87 ? 352 ALA A O   1 O43570 UNP 352 A 
ATOM 2769 N N   . HIS A 1 353 ? -65.520 -27.491 112.553 1.0 56.68 ? 353 HIS A N   1 O43570 UNP 353 H 
ATOM 2770 C CA  . HIS A 1 353 ? -65.746 -27.256 113.987 1.0 56.68 ? 353 HIS A CA  1 O43570 UNP 353 H 
ATOM 2771 C C   . HIS A 1 353 ? -64.769 -27.794 115.055 1.0 56.68 ? 353 HIS A C   1 O43570 UNP 353 H 
ATOM 2772 C CB  . HIS A 1 353 ? -67.215 -27.478 114.390 1.0 56.68 ? 353 HIS A CB  1 O43570 UNP 353 H 
ATOM 2773 O O   . HIS A 1 353 ? -64.548 -28.992 115.190 1.0 56.68 ? 353 HIS A O   1 O43570 UNP 353 H 
ATOM 2774 C CG  . HIS A 1 353 ? -68.125 -26.416 113.839 1.0 56.68 ? 353 HIS A CG  1 O43570 UNP 353 H 
ATOM 2775 C CD2 . HIS A 1 353 ? -68.995 -26.525 112.788 1.0 56.68 ? 353 HIS A CD2 1 O43570 UNP 353 H 
ATOM 2776 N ND1 . HIS A 1 353 ? -68.207 -25.125 114.306 1.0 56.68 ? 353 HIS A ND1 1 O43570 UNP 353 H 
ATOM 2777 C CE1 . HIS A 1 353 ? -69.100 -24.467 113.552 1.0 56.68 ? 353 HIS A CE1 1 O43570 UNP 353 H 
ATOM 2778 N NE2 . HIS A 1 353 ? -69.605 -25.277 112.610 1.0 56.68 ? 353 HIS A NE2 1 O43570 UNP 353 H 
ATOM 2779 N N   . ALA A 1 354 ? -64.412 -26.811 115.904 1.0 44.11 ? 354 ALA A N   1 O43570 UNP 354 A 
ATOM 2780 C CA  . ALA A 1 354 ? -63.816 -26.804 117.248 1.0 44.11 ? 354 ALA A CA  1 O43570 UNP 354 A 
ATOM 2781 C C   . ALA A 1 354 ? -62.285 -26.744 117.346 1.0 44.11 ? 354 ALA A C   1 O43570 UNP 354 A 
ATOM 2782 C CB  . ALA A 1 354 ? -64.502 -27.812 118.172 1.0 44.11 ? 354 ALA A CB  1 O43570 UNP 354 A 
ATOM 2783 O O   . ALA A 1 354 ? -61.606 -27.751 117.061 1.0 44.11 ? 354 ALA A O   1 O43570 UNP 354 A 
ATOM 2784 O OXT . ALA A 1 354 ? -61.853 -25.635 117.741 1.0 44.11 ? 354 ALA A OXT 1 O43570 UNP 354 A 
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