| Protein name |
Integrin alpha-V
|
| Main knot |
31 (85%)
|
| Global pLDDT |
88.19
|
| Species |
Human
|
| UniProt | |
| Structure Prediction Model |
AlphaFold v4:
 P06756
|
| PDB structures | |
| Structures in KnotProt |
 1JV2 A, Artifact S +3.1: 31-987 1L5G A, Artifact S +3.1: 31-987 1M1X A, Artifact K +3.1: 31-987 1U8C A, Artifact S +3.1: 31-987 3IJE A, Artifact K +3.1: 31-997 4G1E A, Artifact K +3.1, +3.1, 4.1, +3.1, +3.1: 31-989 4G1M A, Artifact K 4.1, +3.1: 31-989 4MMX A, Artifact S +3.1: 31-989 4MMY A, Artifact K +3.1: 31-989 4MMZ A, Artifact K +3.1: 31-989 6AVQ A, -3.1: 31-987 6AVR A, -3.1: 31-987 6AVU A, -3.1: 31-987
|
| Model length |
1048
|
| AlphaFold deposition date |
2022-06-01
|
| AlphaKnot deposition date |
2023-01-27
|
| Knot pLDDT | Knot core range | Knot core length | Knot tails range | N-end length | C-end length | Main Knot | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
 |
88.7 | 378-912 | 535 | 1-377, 913-1048 | 377 | 136 |
|
Model Sequence |
MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHVFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET
|
| Protein name |
Integrin alpha-V
|
| Main knot |
31 (88%)
|
| Knot fingerprint |
K 31 31 41 31 31
|
| Global pLDDT |
88.3
|
| Species |
Human
|
| UniProt | |
| Structure Prediction Model |
AlphaFold v1:
P06756
|
| PDB structures | |
| Structures in KnotProt |
1JV2 A, Artifact S +3.1: 31-987 1L5G A, Artifact S +3.1: 31-987 1M1X A, Artifact K +3.1: 31-987 1U8C A, Artifact S +3.1: 31-987 3IJE A, Artifact K +3.1: 31-997 4G1E A, Artifact K +3.1, +3.1, 4.1, +3.1, +3.1: 31-989 4G1M A, Artifact K 4.1, +3.1: 31-989 4MMX A, Artifact S +3.1: 31-989 4MMY A, Artifact K +3.1: 31-989 4MMZ A, Artifact K +3.1: 31-989 6AVQ A, -3.1: 31-987 6AVR A, -3.1: 31-987 6AVU A, -3.1: 31-987
|
| Model length |
1048
|
| AlphaFold deposition date |
2021-07-01
|
| AlphaKnot deposition date |
2021-12-18
|
| Knot pLDDT | Knot core range | Knot core length | Knot tails range | N-end length | C-end length | Main Knot | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
77.4 | 780-979 | 200 | 1-779, 980-1048 | 779 | 69 |
|
Knot | ||||
 |
80.2 | 804-955 | 152 | 1-803, 956-1048 | 803 | 93 | Slipknot |
Model Sequence |
MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHVFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET
|
| Domain |
Eukaryota
|
| Family |
Hominidae
|
| Species (Full Name) |
Homo sapiens
|
| PFAM codes |
PF00357, PF01839, PF08441
|
| InterPro codes |
 IPR000413, IPR013517, IPR013519, IPR013649, IPR018184, IPR028994, IPR032695
|
| PDB structures (whole Protein) |
 1JV2 A: 31-987 1L5G A: 31-987 1M1X A: 31-987 1U8C A: 31-987 3IJE A: 31-997 4G1E A: 31-989 4G1M A: 31-989 4MMX A: 31-989 4MMY A: 31-989 4MMZ A: 31-989 4O02 A: 31-992 4UM8 A/C: 31-625 4UM9 A/C: 31-625 5FFG A: 31-625 5FFO A/E: 31-625 5NEM A: 31-624 5NER A: 31-624 5NET A: 31-624 5NEU A: 31-624 6AVQ A: 31-987 6AVR A: 31-987 6AVU A: 31-987 6DJP A: 31-995 6MK0 A: 31-984 6MSL A: 31-997 6MSU A: 31-997 6NAJ A: 31-984 6OM1 A/C/E/G: 31-624 6OM2 A/C: 31-624 6UJA A: 31-1048 6UJB A: 31-1048 6UJC A: 31-1048 7Y1T A: 1-625
|
#similar chains with experimentally solved models (PDB) in the AlphaKnot 2.0 database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains with experimentally solved models not found in AlphaKnot 2.0 database but found in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
P06756