P08514 | AlphaKnot 2.0

AF4

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Information

Protein name	Integrin alpha-IIb
Main knot	3₁ (88%)
Global pLDDT	88.12
Species	Human
UniProt	P08514
Structure Prediction Model	AlphaFold v4: P08514
PDB structures	1DPK A 1DPQ A 1KUP A 1KUZ A 1M8O A 1S4W A 1TYE A/C/E 2K1A A 2K9J A 2KNC A 2MTP B 2N9Y A 2VC2 A 2VDK A 2VDL A 2VDM A 2VDN A 2VDO A 2VDP A 2VDQ A 2VDR A 3FCS A/C 3FCU A/C/E 3NID A/C 3NIF A/C 3NIG A/C 3T3M A/C 3T3P A/C 3ZDX A/C 3ZDY A/C 3ZDZ A/C 3ZE0 A/C 3ZE1 A/C 3ZE2 A/C 4CAK A 4Z7N A/C 4Z7O A/C 4Z7Q A/C 5HDB A/C 6V4P A 7KN0 A 7L8P A/C 7LA4 A 7TCT A/C 7TD8 A/C 7THO A/C 7TMZ A/C 7TPD A/C 7U60 A/C 7U9F A/C 7U9V A/C 7UBR A/C 7UCY A/C 7UDG A/C 7UDH A/C 7UE0 A/C 7UFH A/C 7UH8 A/C 7UJE A/C 7UJK A/C 7UK9 A/C 7UKO A/C 7UKP A/C 7UKT A/C
Structures in KnotProt	3FCS A/C, Artifact S +3.1: 32-989
Structure in AlphaLasso	P08514: LL_-4,-3 L₀
Model length	1039
AlphaFold deposition date	2022-06-01
AlphaKnot deposition date	2023-01-27

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Knot types & Model sequence

					Knot pLDDT	Knot core range	Knot core length	Knot tails range	N-end length	C-end length	Main Knot
					78.5	785-985	201	1-784, 986-1039	784	54

Model Sequence

MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE

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AF1-Unsure

Categories voted by users:

Information

Protein name	Integrin alpha-IIb
Main knot	3₁ (88%)
Knot fingerprint	K 3₁ 3₁ 4₁ 3₁ 3₁
Global pLDDT	88.3
Species	Human
UniProt	P08514
Structure Prediction Model	AlphaFold v1: P08514
PDB structures	1DPK A 1DPQ A 1JX5 A 1KUP A 1KUZ A 1M8O A 1RN0 A 1S4W A 1TYE A/C/E 1UV9 A 2K1A A 2K9J A 2KNC A 2MTP B 2N9Y A 2VC2 A 2VDK A 2VDL A 2VDM A 2VDN A 2VDO A 2VDP A 2VDQ A 2VDR A 3FCS A/C 3FCU A/C/E 3NID A/C 3NIF A/C 3NIG A/C 3T3M A/C 3T3P A/C 3ZDX A/C 3ZDY A/C 3ZDZ A/C 3ZE0 A/C 3ZE1 A/C 3ZE2 A/C 4CAK A 4Z7N A/C 4Z7O A/C 4Z7Q A/C 5HDB A/C 6V4P A
Structures in KnotProt	3FCS A/C, Artifact S +3.1: 32-989
Structure in AlphaLasso	P08514: LL_-4,-3 L₀
Model length	1039
AlphaFold deposition date	2021-07-01
AlphaKnot deposition date	2021-12-18

Knot map

Knot cutoff: 48%

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Knot types & Model sequence

					Knot pLDDT	Knot core range	Knot core length	Knot tails range	N-end length	C-end length	Main Knot
					76.4	790-986	197	1-789, 987-1039	789	53		Knot
					79.0	808-960	153	1-807, 961-1039	807	79		Slipknot

Model Sequence

Comments

Domain	Eukaryota
Family	Hominidae
Species (Full Name)	Homo sapiens
PFAM codes	PF00357, PF01839, PF08441
InterPro codes	IPR000413, IPR013517, IPR013519, IPR013649, IPR018184, IPR028994, IPR032695
PDB structures (whole Protein)	1DPK A: 1020-1039 1DPQ A: 1020-1039 1JX5 A: 32-483 1KUP A: 1018-1028 1KUZ A: 1018-1028 1M8O A: 1020-1039 1RN0 A: 32-482 1S4W A: 1020-1039 1TYE A/C/E: 32-483 1UV9 A: 32-973 2K1A A: 989-1029 2K9J A: 989-1029 2KNC A: 991-1039 2MTP B: 1019-1039 2N9Y A: 989-1029 2VC2 A: 32-483 2VDK A: 32-483 2VDL A: 32-483 2VDM A: 32-483 2VDN A: 32-483 2VDO A: 32-483 2VDP A: 32-483 2VDQ A: 32-483 2VDR A: 32-483 3FCS A/C: 32-989 3FCU A/C/E: 32-488 3NID A/C: 32-488 3NIF A/C: 32-488 3NIG A/C: 32-488 3T3M A/C: 32-488 3T3P A/C: 32-488 3ZDX A/C: 32-488 3ZDY A/C: 32-488 3ZDZ A/C: 32-488 3ZE0 A/C: 32-488 3ZE1 A/C: 32-488 3ZE2 A/C: 32-488 4CAK A: 32-989 4Z7N A/C: 32-486 4Z7O A/C: 32-486 4Z7Q A/C: 32-485 5HDB A/C: 32-485 6V4P A: 1-963 7KN0 A: 989-1029 7L8P A/C: 32-488 7LA4 A: 1-1039 7TCT A/C: 32-488 7TD8 A/C: 32-484 7THO A/C: 32-485 7TMZ A/C: 32-485 7TPD A/C: 32-488 7U60 A/C: 32-486 7U9F A/C: 32-485 7U9V A/C: 32-485 7UBR A/C: 32-485 7UCY A/C: 32-488 7UDG A/C: 32-488 7UDH A/C: 32-488 7UE0 A/C: 32-488 7UFH A/C: 32-488 7UH8 A/C: 32-488 7UJE A/C: 32-485 7UJK A/C: 32-488 7UK9 A/C: 32-488 7UKO A/C: 32-488 7UKP A/C: 32-488 7UKT A/C: 32-488

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P08514F1

AF4

Model Sequence

AF1-Unsure

Model Sequence