P25054 | AlphaKnot 2.0

AF1-Unassigned

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Information

Protein name	Adenomatous polyposis coli protein
Main knot	Unknown (100%)
Knot fingerprint	K Unknown(x4) 6₁(x15) 4₁ 3₁(x9)
Global pLDDT	41.9
Species	Human
UniProt	P25054
Structure Prediction Model	AlphaFold v1: P25054
PDB structures	1EMU B 1T08 C 1TH1 C/D 1V18 B 2RQU B
Model length	1400
AlphaFold deposition date	2021-07-01
AlphaKnot deposition date	2021-12-18

Knot map

Knot cutoff: 48%

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Knot types & Model sequence

Knot pLDDT	Knot core range	Knot core length	Knot tails range	N-end length	C-end length
41.1	199-1193	995	1-198, 1194-1400	198	207	Knot
43.7	223-753	531	1-222, 754-1400	222	647	Slipknot
41.9	67-1235	1169	1-66, 1236-1400	66	165	Slipknot
41.1	409-1202	794	1-408, 1203-1400	408	198	Slipknot

Model Sequence

IASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQSGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSA

Knotting comparison of models

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Comments

Domain	Eukaryota
Family	Hominidae
Species (Full Name)	Homo sapiens
PDB structures (whole Protein)	1DEB A/B: 2-55 1EMU B: 2034-2049 1JPP C/D: 1021-1035 1M5I A: 126-250 1T08 C: 1484-1498 1TH1 C/D: 1362-1540 1V18 B: 1482-1528 2RQU B: 1578-1596 3AU3 A: 396-732 3NMW A/B: 407-751 3NMX A/B/C: 407-751 3NMZ A/B: 303-739 3QHE A/C: 396-732 3RL7 G/H/I/J/K/L: 2833-2843 3RL8 F: 2833-2843 3T7U A/B: 407-775 4G69 B: 2833-2843 4YJE A: 407-751 4YJL A/B/C/D/E/F: 407-751 4YK6 A: 407-751 5B6G A: 407-751 5IZ6 A: 407-751 5IZ8 A/B: 407-751 5IZ9 A: 407-751 5IZA A: 407-751 5Z8H A: 407-741 7F6M A: 407-751 7F7O A: 407-738 7XTY C/D: 2833-2843 8GSJ A: 407-738 8X2Q A: 126-250

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similar chains with experimentally solved models (PDB) in the AlphaKnot 2.0 database (?% sequence similarity)

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similar chains with experimentally solved models not found in AlphaKnot 2.0 database but found in thePDB database (?% sequence similarity)

#similar chains with experimentally solved models (PDB) in the AlphaKnot 2.0 database (?% sequence similarity)
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#similar chains, but unknotted
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        #similar chains with experimentally solved models not found in AlphaKnot 2.0 database but found in the pdb database (?% sequence similarity)
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P25054F8

AF1-Unassigned

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Model Sequence