| Knot pLDDT | Knot core range | Knot core length | Knot tails range | N-end length | C-end length | Main Knot | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
 |
97.6 | 26-282 | 257 | 1-25, 283-395 |
|
Model Sequence |
MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY
|
| Protein name |
S-adenosylmethionine synthase isoform type-2
|
| Main knot |
31 (66%)
|
| Knot fingerprint |
K 31
|
| Global pLDDT |
96.2
|
| Species |
Human
|
| UniProt | |
| Structure Prediction Model |
AlphaFold v1:
 P31153
|
| PDB structures | |
| Structures in KnotProt |
 2P02 A, K +3.1: 1-395 4KTT A/B/C/D, K +3.1: 1-395 4KTV A/B/C/D, K +3.1: 1-395 4NDN A/B/C/D, K +3.1: 1-395 5A19 A, K +3.1: 1-395 5A1G A, K +3.1: 1-395 5A1I A, K +3.1: 1-395 5UGH A/B/C/D, K +3.1, +3.1: 1-395 6FAJ A/B, +3.1: 1-395 6FBN A/B, +3.1: 1-395 6FBO A, +3.1: 1-395 6FBP A/B, +3.1: 1-395 6FCB A, +3.1: 1-395 6FCD A, +3.1: 1-395 6FWB A/B/C/D, +3.1: 1-394 6G6R A, +3.1: 1-395 6P9V A, +3.1: 1-395 6WKB A/B, +3.1: 1-395 7BHR A, +3.1: 1-395 7BHS A, +3.1: 1-395 7BHT A, +3.1: 1-395 7BHU A, +3.1: 1-395 7BHV A, +3.1: 1-395 7BHW A, +3.1: 1-395 7BHX A, +3.1: 1-395 7KCC A, +3.1: 1-395 7KCE A, +3.1: 1-395 7KCF A, +3.1: 1-395 7KDA A, +3.1: 1-395 7KDB A, +3.1: 1-395 7L1A A, +3.1: 1-395
|
| Model length |
395
|
| AlphaFold deposition date |
2021-07-01
|
| AlphaKnot deposition date |
2021-12-18
|
Knot cutoff: 48%
| Knot pLDDT | Knot core range | Knot core length | Knot tails range | N-end length | C-end length | Main Knot | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
97.6 | 26-280 | 255 | 1-25, 281-395 |
|
Model Sequence |
MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY
|
| Knot pLDDT | Knot core range | Knot core length | Knot tails range | N-end length | C-end length | Main Knot | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
73.9 | 26-286 | 261 | 1-25, 287-395 |
|
Model Sequence |
MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY
|
| Domain |
Eukaryota
|
| Family |
Hominidae
|
| Species (Full Name) |
Homo sapiens
|
| PFAM codes |
PF00438, PF02772, PF02773
|
| InterPro codes |
 IPR002133, IPR022628, IPR022629, IPR022630, IPR022631, IPR022636
|
| PDB structures (whole Protein) |
 2P02 A: 1-395 4KTT A/B/C/D: 1-395 4KTV A/B/C/D: 1-395 4NDN A/B/C/D: 1-395 5A19 A: 1-395 5A1G A: 1-395 5A1I A: 1-395 5UGH A/B/C/D: 1-395 6FAJ A/B: 1-395 6FBN A/B: 1-395 6FBO A: 1-395 6FBP A/B: 1-395 6FCB A: 1-395 6FCD A: 1-395 6FWB A/B/C/D: 1-394 6G6R A: 1-395 6P9V A: 1-395 6WKB A/B: 1-395 7BHR A: 1-395 7BHS A: 1-395 7BHT A: 1-395 7BHU A: 1-395 7BHV A: 1-395 7BHW A: 1-395 7BHX A: 1-395 7KCC A: 1-395 7KCE A: 1-395 7KCF A: 1-395 7KDA A: 1-395 7KDB A: 1-395 7L1A A: 1-395 7LNH A/B: 1-395 7RW5 A/B/C/D: 1-395 7RW7 A: 1-395 7RWG A: 1-395 7RWH A: 1-395 7RXV A: 1-395 7RXW A: 1-395 7RXX A: 1-395
|
#similar chains with experimentally solved models (PDB) in the AlphaKnot 2.0 database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains with experimentally solved models not found in AlphaKnot 2.0 database but found in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
P31153