Q03164 | AlphaKnot 2.0

AF1-Unassigned

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Information

Protein name	Histone-lysine N-methyltransferase 2A
Main knot	Unknown (84%)
Knot fingerprint	K Unknown 3₁#5₁(x4) 5₁(x17) 3₁(x8)
Global pLDDT	39.4
Species	Human
UniProt	Q03164
Structure Prediction Model	AlphaFold v1: Q03164
PDB structures	2AGH C 2LXS B 2LXT B 5SVH B
Model length	1400
AlphaFold deposition date	2021-07-01
AlphaKnot deposition date	2021-12-18

Knot map

Knot cutoff: 48%

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Knot types & Model sequence

Knot pLDDT	Knot core range	Knot core length	Knot tails range	N-end length	C-end length
39.7	60-1258	1199	1-59, 1259-1400	59	142	Knot
41.3	473-869	397	1-472, 870-1400	472	531	Slipknot
43.0	465-1059	595	1-464, 1060-1400	464	341	Slipknot
39.8	118-1348	1231	1-117, 1349-1400	117	52	Slipknot

Model Sequence

SPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSS

Knotting comparison of models

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Comments

Domain	Eukaryota
Family	Hominidae
Species (Full Name)	Homo sapiens
PDB structures (whole Protein)	2AGH C: 2840-2869 2J2S A: 1143-1214 2JYI A: 1147-1203 2KKF A: 1147-1203 2KU7 A: 1585-1628 2KYU A: 1564-1628 2LXS B: 2840-2858 2LXT B: 2840-2858 2MSR A: 140-160 2MTN A: 110-160 2W5Y A: 3785-3969 2W5Z A: 3785-3969 3EG6 C: 3762-3773 3EMH B: 3764-3776 3LQH A: 1566-1784 3LQI A/B/C: 1566-1784 3LQJ A/B: 1566-1784 3P4F C: 3761-3770 3U85 B: 6-25 3U88 M/N: 103-153 4ESG C/D: 3755-3771 4GQ6 B: 6-15 4NW3 A: 1147-1204 5F5E A: 3813-3969 5F6L A: 3813-3969 5SVH B: 2839-2869 6EMQ A: 111-160 6KIU K: 3754-3969 6KIV K: 3754-3969 6KIX K: 3754-3969 6KIZ K: 3754-3969 6PWV C: 3762-3969 6PWW C: 3762-3969 6U9K A/B: 3813-3969 6U9M A/B: 3813-3969 6U9N A/B: 3813-3969 6U9R A/B: 3813-3969 6W5I C: 3762-3969 6W5M C: 3762-3969 6W5N C: 3762-3969

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similar chains with experimentally solved models not found in AlphaKnot 2.0 database but found in thePDB database (?% sequence similarity)

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Q03164F12

AF1-Unassigned

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Model Sequence