Q12791 | AlphaKnot 2.0

AF4

Categories voted by users:

Information

Protein name	Calcium-activated potassium channel subunit alpha-1
Main knot	3₁ (69%)
Global pLDDT	76.98
Species	Human
UniProt	Q12791
Structure Prediction Model	AlphaFold v4: Q12791
PDB structures	2K44 A 3MT5 A 3NAF A 6ND0 A/B/C/D 6V22 A/B/C/D 6V35 A/B/C/D 6V38 A/B/C/D 6V3G A/B/C/D 6V5A A
Structures in KnotProt	3MT5 A, K -3.1: 406-1179 6ND0 A/B/C/D, -3.1: 292-1175 6V22 A/B/C/D, -3.1: 66-1179 6V35 A/B/C/D, -3.1: 66-1179 6V3G A/B/C/D, -3.1: 66-1179 6V5A A, -3.1: 406-1179
Structure in AlphaLasso	Q12791: L_+3C
Model length	1236
AlphaFold deposition date	2022-06-01
AlphaKnot deposition date	2023-01-27

Help

Knot types & Model sequence

					Knot pLDDT	Knot core range	Knot core length	Knot tails range	N-end length	C-end length	Main Knot
					78.4	413-1046	634	1-412, 1047-1236	412	190

Model Sequence

MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSERDCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFRAFEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKSRESRDKQKYVQEERL

Comments

AF1-Knot

Categories voted by users:

Information

Protein name	Calcium-activated potassium channel subunit alpha-1
Main knot	3₁ (72%)
Knot fingerprint	K 3₁ 3₁ 3₁
Global pLDDT	76.0
Species	Human
UniProt	Q12791
Structure Prediction Model	AlphaFold v1: Q12791
PDB structures	2K44 A 3MT5 A 3NAF A 6ND0 A/B/C/D 6V22 A/B/C/D 6V35 A/B/C/D 6V38 A/B/C/D 6V3G A/B/C/D 6V5A A
Structures in KnotProt	3MT5 A, K -3.1: 406-1179 6ND0 A/B/C/D, -3.1: 292-1175 6V22 A/B/C/D, -3.1: 66-1179 6V35 A/B/C/D, -3.1: 66-1179 6V3G A/B/C/D, -3.1: 66-1179 6V5A A, -3.1: 406-1179
Structure in AlphaLasso	Q12791: L_+3C
Model length	1236
AlphaFold deposition date	2021-07-01
AlphaKnot deposition date	2021-12-18

Knot map

Knot cutoff: 48%

Help Knotting data interpretation

Help

Knot types & Model sequence

					Knot pLDDT	Knot core range	Knot core length	Knot tails range	N-end length	C-end length	Main Knot
					76.1	551-1084	534	1-550, 1085-1236	550	152

Model Sequence

Comments

Domain	Eukaryota
Family	Hominidae
Species (Full Name)	Homo sapiens
PFAM codes	PF00520, PF03493
InterPro codes	IPR003929, IPR005821, IPR036291
PDB structures (whole Protein)	2K44 A: 257-284 3MT5 A: 406-1179 3NAF A: 395-681,782-1182 6ND0 A/B/C/D: 292-1175 6V22 A/B/C/D: 66-1179 6V35 A/B/C/D: 66-1179 6V38 A/B/C/D: 66-1179 6V3G A/B/C/D: 66-1179 6V5A A: 406-1179

...loading similar chains, please wait...
similar chains with experimentally solved models (PDB) in the AlphaKnot 2.0 database (?% sequence similarity)

...loading similar chains, please wait...
similar chains with experimentally solved models not found in AlphaKnot 2.0 database but found in thePDB database (?% sequence similarity)

#similar chains with experimentally solved models (PDB) in the AlphaKnot 2.0 database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
        #similar chains with experimentally solved models not found in AlphaKnot 2.0 database but found in the pdb database (?% sequence similarity)
        ...loading similar chains, please wait...

Q12791F1

AF4

Model Sequence

AF1-Knot

Model Sequence