Q8NEZ4F9

Histone-lysine N-methyltransferase 2C
AF1-Unassigned
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Information
Protein name
Histone-lysine N-methyltransferase 2C
Main knot
Unknown (59%)
Knot fingerprint
K Unknown 62(x10) 41(x6) 31(x4)
Global pLDDT
45.8
Species
Human
UniProt
Structure Prediction Model
AlphaFold v1:  Q8NEZ4
PDB structures
Model length
1400
AlphaFold deposition date
2021-07-01
AlphaKnot deposition date
2021-12-18
Knot map

Knot cutoff: 48%


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Knot types & Model sequence
Knot pLDDT Knot core range Knot core length Knot tails range N-end length C-end length Main Knot
40.2 334-1106 773 1-333, 1107-1400 333 294 Knot
37.7 322-618 297 1-321, 619-1400 321 782 Slipknot
40.1 284-892 609 1-283, 893-1400 283 508 Slipknot
40.5 369-897 529 1-368, 898-1400 368 503 Slipknot
Model Sequence
NSAFNPMASDPNNSWTSSAPTVEGENDTMSNAQRSTLKWEKEEALGEMATVAPVLYTNINFPNLKEEFPDWTTRVKQIAKLWRKASSQERAPYVQKARDNRAALRINKVQMSNDSMKRQQQQDSIDPSSRIDSELFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQQQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIAGRQEKGSQDSPAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPRYAVFPKDQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLVPPQQIQGSGVSPQLRRSVSVDMPRPLNNSQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGSVVEASSNLRHGNFIPRPDFPGPRHTDPMRRPPQGLPNQLPVHPDLEQVPPSQQEQGHSVHSSSMVMRTLNHPLGGEFSEAPLSTSVPSETTSDNLQITTQPSDGLEEKLDSDDPSVKELDVKDLEGVEVKDLDDEDLENLNLDTEDGKVVELDTLDNLETNDPNLDDLLRSGEFDIIAYTDPELDMGDKKSMFNEELDLPIDDKLDNQCVSVEPKKKEQENKTLVLSDKHSPQKKSTVTNEVKTEVLSPNSKVESKCETEKNDENKDNVDTPCSQASAHSDLNDGEKTSLHPCDPDLFEKRTNRETAGPSANVIQASTQLPAQDVINSCGITGSTPVLSSLLANEKSDNSDIRPSGSPPPPTLPASPSNHVSSLPPFIAPPGRVLDNAMNSNVTVVSRVNHVFSQGVQVNPGLIPGQSTV
Knotting comparison of models
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Comments
Domain Eukaryota
Family Hominidae
Species (Full Name) Homo sapiens
PDB structures (whole Protein)  2YSM A: 342-439  2YUK A: 1631-1713  3UVL B: 4707-4717  4ERY D: 4703-4716  5F59 A: 4757-4910  5F6K C/E: 4757-4911  6KIW K: 4707-4911  6MLC A/B/C/D: 1055-1144
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similar chains with experimentally solved models (PDB) in the AlphaKnot 2.0 database (?% sequence similarity)
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similar chains with experimentally solved models not found in AlphaKnot 2.0 database but found in thePDB database (?% sequence similarity)

 
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